ライフサイエンスコーパス: acetylcholine

1 shows unique modulation by endogenous DA and acetylcholine.

2 tic acid produced by enzymatic hydrolysis of acetylcholine.

3 tion by enhancing the presynaptic release of acetylcholine.

4 the neocortical tone is sustained mainly by acetylcholine.

5 he enzyme that produces the neurotransmitter acetylcholine.

6 s that are altered by nicotine, menthol, and acetylcholine.

7 s (NB) of Meynert, the source of neocortical acetylcholine [9, 10], provides a potential method of im

8 en the predominant efferent neurotransmitter acetylcholine (ACh) activates calyceal nicotinic ACh rec

9 on of the endothelium-dependent vasodilators acetylcholine (ACh) and adenosine triphosphate (ATP), th

10 urons excite Renshaw cells by releasing both acetylcholine (ACh) and glutamate.

11 xplained as a function of neuromodulation by acetylcholine (ACh) and norepinephrine (NE) and afferent

12 apeutic potential.SIGNIFICANCE STATEMENT The acetylcholine (ACh) arousal system in the brain is neede

13 he AcFETs were used to record the release of acetylcholine (ACh) by neuronal tissue cultivated on the

14 An essential biological sensor for acetylcholine (ACh) detection is constructed by immobili

15 one (PT-1284 ( 1: )) was shown to potentiate acetylcholine (ACh) in an M1 fluorometric imaging plate

16 Here we demonstrate a role for acetylcholine (ACh) in Drosophila.

17 KEY POINTS: Phasic release of acetylcholine (ACh) in the neocortex facilitates attenti

18 Phasic release of acetylcholine (ACh) in the neocortex facilitates attenti

19 Acetylcholine (ACh) increased [Ca(2+) ]i with a time cou

20 Acetylcholine (ACh) is a potent neuromodulator capable o

21 The neuromodulator acetylcholine (ACh) is crucial for several cognitive fun

22 pletion studies show that the neuromodulator acetylcholine (ACh) is essential to dlPFC working memory

23 Acetylcholine (ACh) is the most important parasympatheti

24 A novel study shows that increasing cortical acetylcholine (ACh) levels alter specific aspects of the

25 s (GTs), which is associated with attenuated acetylcholine (ACh) levels in prefrontal cortex.

26 e under altered brain states associated with acetylcholine (ACh) levels, such as attention and arousa

27 erentiation and fusion, significantly larger acetylcholine (ACh) receptor clusters, and increased exp

28 ABSTRACT: Gq -coupled M1-type muscarinic acetylcholine (ACh) receptors (mAChRs) mediate two disti

29 Gq -coupled M1-type muscarinic acetylcholine (ACh) receptors (mAChRs) mediate two disti

30 erneurons (CINs) and activation of nicotinic acetylcholine (ACh) receptors (nAChRs) in DA neuron (DAN

31 KEY POINTS: Neuromuscular acetylcholine (ACh) receptors have a high affinity for t

32 e a retrograde synaptic signal that inhibits acetylcholine (ACh) release at neuromuscular junctions.

33 ABSTRACT: Acetylcholine (ACh) released at the vertebrate nerve-mus

34 uft cells and nerves are the main sources of acetylcholine (ACh) within the gastric mucosa.

35 tagonist, atropine, eliminated the effect of acetylcholine (ACh), but not of light, on isolated mouse

36 capacity to produce, release, and respond to acetylcholine (ACh), but the functional role of choliner

37 We therefore investigated how acetylcholine (ACh), known to drive brain states of atte

38 howed that activation of CB2Rs by GW reduced acetylcholine (ACh)-, but not cholecystokinin (CCK)-indu

39 Therefore, in neuropathic pain rats, the acetylcholine (ACh)-dependent increase in neuronal excit

40 scle contraction was evaluated by inhibiting acetylcholine (ACh)-induced Pak activation through the e

41 vels of important neurotransmitters, such as acetylcholine (ACh).

42 oltage-clamp method to quantify responses to acetylcholine (ACh): agonist sensitivity (EC50), maximal

43 f the paradigm neurotransmitter receptor for acetylcholine (AChR) display a series of cholesterol con

44 hat the CT neurons are potently modulated by acetylcholine acting on both nicotinic and muscarinic ac

45 Unexpectedly, even in the absence of acetylcholine, after G-protein inactivation with pertuss

46 -cell currents in response to application of acetylcholine alone or co-applied with PhTX analogue wer

47 utamate, gamma-aminobutyric acid (GABA), and acetylcholine, also have associated proteins, which may

48 eurotransmitters as endogenous motor neurons-acetylcholine and a combination of adenosine triphosphat

49 e that sequential neuromodulation of STDP by acetylcholine and dopamine offers an efficacious model o

50 rminals, which, in turn, enhances release of acetylcholine and inhibition of the IHCs.

51 acid, an antagonist of both alpha7 nicotinic acetylcholine and N-methyl-D-aspartate receptors.

52 in part to the functional similarity between acetylcholine and nicotine, a known appetite suppressant

53 inobutyric acid (GABA), dopamine, serotonin, acetylcholine and opioids-and numerous ion channels were

54 riction, as evidenced by increased pulmonary acetylcholine and phosphorylated myosin light chain 2 in

55 4 serotonin, dopamine, histamine, melatonin, acetylcholine, and adrenergic receptors.

56 Here we assess the roles of noradrenaline, acetylcholine, and dopamine within a single, unified com

57 itions requires understanding how glutamate, acetylcholine, and GABA signals are precisely coordinate

58 arkedly improved positive cooperativity with acetylcholine, and retained exquisite selectivity for th

59 s a brainstem nucleus containing glutamate-, acetylcholine-, and GABA-releasing neurons with connecti

60 Hugin neuropeptide and acetylcholine are both necessary for the regulatory effe

61 minant of signalling by the neurotransmitter acetylcholine at both central and peripheral cholinergic

62 olinesterase (AChE) is crucial for degrading acetylcholine at cholinergic synapses.

63 rectly quantified the local concentration of acetylcholine at the neuromuscular junction of frog cuta

64 results link visuospatial tuning effects of acetylcholine at the neuronal and perceptual levels and

65 tly measure the quantity and distribution of acetylcholine at the subcellular level.

66 of 14 neurochemicals, including dopamine and acetylcholine, at basal conditions.

67 FASD pup brains showed evidence of altered acetylcholine availability and Dnmt3a mRNA was reduced i

68 l data in mouse hippocampal slices show that acetylcholine biases STDP toward synaptic depression, wh

69 Through studies with ligand binding to the acetylcholine binding protein (AChBP), we previously ide

70 llular domains of adjacent subunits lies the acetylcholine binding site, composed of a principal comp

71 izophrenia, but the high conservation of the acetylcholine-binding pocket has spurred current researc

72 ace plasmon resonance spectroscopy of alpha7-acetylcholine-binding protein (AChBP), a humanized chime

73 ei have 15 Cys-loop receptor subunits and an acetylcholine-binding protein (AChBP).

74 Acetylcholine caused endothelium-dependent dilatation th

75 ta2 was potentiated at low concentrations of acetylcholine chloride (ACh) and physostigmine, whereas

76 Compared with neuronal nicotinic acetylcholine cholinergic receptors (nAChRs) assembled f

77 Acetylcholine concentration-response curves and maximum

78 We investigated whether a stable analogue of acetylcholine could raise ventricular fibrillation thres

79 er negatively-charged neurotransmitters like acetylcholine demonstrated the selectivity of our detect

80 The neurotransmitter acetylcholine, derived from the medial septum/diagonal b

81 n intensity at AJs, (iii) AJ width, and (iv) acetylcholine dilatation.

82 ith the FBA, saracatinib no longer increased acetylcholine dilatation.

83 and [(3)H]NMS binding was reduced by Zn(2+), acetylcholine displacement of [(3)H]NMS binding was enha

84 S binding was enhanced by Mg(2+) and Zn(2+), acetylcholine displacement of [(3)H]pirenzepine was redu

85 We demonstrate that optogenetically-enhanced acetylcholine during initial contextual exploration lead

86 een assessed for their capacities to inhibit acetylcholine esterase but, in contrast to the predictio

87 e residues and HbA1c but no association with acetylcholine esterase was noticed.

88 c integrity through binding the ColQ tail of acetylcholine esterase.

89 se intolerance with no significant change in acetylcholine esterase.

90 Removal of acetylcholine from prefrontal cortex can disrupt short-t

91 expressed by subpopulations of neurons using acetylcholine, GABA, or serotonin as neurotransmitters.

92 ate of head undulations by acting through an acetylcholine-gated channel and a muscarinic acetylcholi

93 ss Cre recombinase only in neurons producing acetylcholine, glutamate, or GABA.

94 Acetylcholine has long been proposed to influence feedin

95 he rate-limiting enzyme in the production of acetylcholine (i.e., choline acetyltransferase).

96 ses reveal that these neurons likely release acetylcholine in addition to serotonin and that exogenou

97 Endothelium-dependent responses to acetylcholine in pressurized mesenteric arteries were re

98 nergic stimulation requires local release of acetylcholine in the basal forebrain and activation of c

99 Acetylcholine in the neocortex is critical for executive

100 ith higher amounts of dopamine compared with acetylcholine in the striatum.

101 nergistic effects in extracellular levels of acetylcholine in the ventral hippocampus.

102 cking antibody, FBA) inhibited dilatation to acetylcholine in young, but not old, arteries.

103 Endothelium-dependent vasodilators, such as acetylcholine, increase intracellular Ca(2+) through act

104 sham-operated animals, focal application of acetylcholine induced a left shift of the input/output c

105 sensor, we confirmed that atropine inhibited acetylcholine-induced decreases in cAMP.

106 helial dysfunction, as evidenced by impaired acetylcholine-induced relaxation of aortic segments and

107 Acetylcholine-induced vasodilation was also impaired in

108 ts to H2O2 for 6 hours dramatically impaired acetylcholine-induced vasorelaxation, reduced NO levels

109 Plk1 knockdown inhibited acetylcholine-induced vimentin phosphorylation at Ser-56

110 l selective attention.SIGNIFICANCE STATEMENT Acetylcholine influences how visual cortical neurons int

111 or the first time that label-free imaging of acetylcholine is achieved with frequency-modulated spect

112 Acetylcholine is an important neurotransmitter that rela

113 ing presynaptic choline uptake and releasing acetylcholine is attenuated in sign-trackers.

114 .SIGNIFICANCE STATEMENT The neurotransmitter acetylcholine is known to be important for cognitive pro

115 Acetylcholine is released in the prefrontal cortex (PFC)

116 The release of acetylcholine is therefore responsible for spontaneous d

117 placement sensor for discriminating choline, acetylcholine, L-carnitine, and glycine betaine effectiv

118 nd to examine sex differences in the dose of acetylcholine leading to a positive acetylcholine provoc

119 shares a highly conserved binding site with acetylcholine, making it difficult to evolve resistance

120 In contrast, stimulation of alpha7 nAChRs by acetylcholine may mediate the increased depression-like

121 dihydroquinoline-3-carboxylic acid, enhanced acetylcholine-mediated phosphorylation at Ser(228) These

122 ted with DHI exhibited significantly greater acetylcholine-mediated relaxation.

123 The neuromodulator acetylcholine modulates spatial integration in visual co

124 gic GABAA , muscarinic M1 , M2 and nicotinic acetylcholine (nACh; alpha4 beta2 subtype), noradrenergi

125 yed by the choline transporter in sustaining acetylcholine neurotransmission at both central and neur

126 addition to the endogenous neurotransmitter acetylcholine, nicotine also binds and activates nAChRs

127 ects of the parasympathetic neurotransmitter acetylcholine on heart rate leading to tachycardia.

128 in this brain region mediate the effects of acetylcholine on the release of other neurotransmitters

129 Stimulation of lymphatic endothelium by acetylcholine or a TRPV4 channel agonist increased intra

130 em, a neurophysiological "two-concentration" acetylcholine or carbachol paradigm was developed and va

131 In this study, we present the first acetylcholine/oxygen hybrid enzymatic fuel cell for the

132 attenuated by fire simulation in response to acetylcholine (P=0.01) and sodium nitroprusside (P=0.004

133 We also used spirometry to test BHR to acetylcholine (PC20Ach).

134 e, which is characterized by degeneration of acetylcholine-producing neurons.

135 dose of acetylcholine leading to a positive acetylcholine provocation test (ACH test).

136 at the neuromuscular junction, primarily the acetylcholine receptor (AChR) and the muscle-specific ki

137 protein at synapse), which is essential for acetylcholine receptor (AChR) clustering and NMJ (neurom

138 xamined expression of genes involved in anti-acetylcholine receptor (AChR) response in MG, MHC class

139 er they produce autoantibodies targeting the acetylcholine receptor (AChR-MG) or muscle specific kina

140 Two alpha4beta2 nicotinic acetylcholine receptor (alpha4beta2-nAChR) isoforms exis

141 ccumulation in BMEC through Alpha7 nicotinic acetylcholine receptor (alpha7 nAChR).

142 ormal and cancer cells, the alpha7 nicotinic acetylcholine receptor (alpha7-nAChR), was more highly e

143 ypothesized that agonism on alpha7 nicotinic acetylcholine receptor (alpha7nAChR) in fetal microglia

144 show that ILC2s express the alpha7-nicotinic acetylcholine receptor (alpha7nAChR), which is thought t

145 linergic fibers through the alpha7-nicotinic acetylcholine receptor (alpha7nAChR), whose activation d

146 teric modulators (PAMs) of the M1 muscarinic acetylcholine receptor (M1 mAChR) are a promising strate

147 ne receptors, particularly the M1 muscarinic acetylcholine receptor (M1 mAChR), which was previously

148 The M2 muscarinic acetylcholine receptor (M2R) was found to exhibit depola

149 function regulated through the M3-muscarinic acetylcholine receptor (M3-mAChR).

150 uction of antinuclear and anti-M3 muscarinic acetylcholine receptor (M3R) autoantibodies and impairme

151 stibular afferents is mediated by muscarinic acetylcholine receptor (mAChR) activation and the subseq

152 Muscarinic acetylcholine receptor (mAChR) activation in rRPa contri

153 Nanoinjections of the muscarinic acetylcholine receptor (mAChR) agonist, oxotremorine, or

154 Muscarinic acetylcholine receptor (mAChR) blockade by scopolamine p

155 e allosteric modulators of the M5 muscarinic acetylcholine receptor (mAChR) have been described, but

156 in signaling of the M1 subtype of muscarinic acetylcholine receptor (mAChR) in the prefrontal cortex

157 Selective activation of the M1 muscarinic acetylcholine receptor (mAChR) via a positive allosteric

158 ve processes that are modulated by nicotinic acetylcholine receptor (nAChR) activation by cholinergic

159 ending plasma levels of the alpha7-nicotinic acetylcholine receptor (nAChR) agonist 3-(2,4-dimethoxyb

160 Among them is epibatidine, a nicotinic acetylcholine receptor (nAChR) agonist that is lethal at

161 icotine or ABT-418, an alpha4beta2 nicotinic acetylcholine receptor (nAChR) agonist, normalized MSO t

162 GeXIVA inhibits the alpha9alpha10 nicotinic acetylcholine receptor (nAChR) and is analgesic in anima

163 These effects were blocked by the nicotinic acetylcholine receptor (nAChR) antagonist mecamylamine.

164 a desensitized state of the alpha7 nicotinic acetylcholine receptor (nAChR) have been associated with

165 with this soluble surrogate of the nicotinic acetylcholine receptor (nAChR) in a cooperative fashion,

166 The nicotinic acetylcholine receptor (nAChR) is a major target of auto

167 The alpha4beta2 nicotinic acetylcholine receptor (nAChR) is important in central n

168 al role in the characterization of nicotinic acetylcholine receptor (nAChR) structure and function an

169 A7, the gene coding for the alpha7 nicotinic acetylcholine receptor (nAChR), and manifest a variable

170 CHRNA7, encoding for the alpha7 nicotinic acetylcholine receptor (nAChR), has been suggested as a

171 (PAMs) acting on the human alpha7 nicotinic acetylcholine receptor (nAChR).

172 hat the Chrm4 transcript encoding muscarinic acetylcholine receptor 4 (M4) is excessively translated,

173 ipts of several targets, including nicotinic acetylcholine receptor alpha 1 and alpha 2 subunit, the

174 s, RV inflammation, and RV alpha-7 nicotinic acetylcholine receptor and muscarinic acetylcholine type

175 Scopolamine (hyoscine) is a muscarinic acetylcholine receptor antagonist that has traditionally

176 that scopolamine, a nonselective muscarinic acetylcholine receptor antagonist, produces rapid antide

177 eaningful improvements in patients with anti-acetylcholine receptor antibody-positive refractory gene

178 us receptor activity using the muscarinic M2 acetylcholine receptor as a model.

179 of response to rituximab in the treatment of acetylcholine receptor autoantibody-positive (AChR+) gen

180 ination/retraction, vesicle accumulation and acetylcholine receptor clustering and acetylcholinestera

181 Studies of the mutant acetylcholine receptor expressed in HEK 293 cells reveal

182 bind to the binding pocket of the muscarinic acetylcholine receptor formed by transmembrane alpha-hel

183 at most synaptic sites, induction of "fetal" acetylcholine receptor gamma subunit (AChRgamma), reduct

184 ociations with sequence variants in nicotine acetylcholine receptor genes and at other loci.

185 its are the most abundant class of nicotinic acetylcholine receptor in the brain.

186 The muscarinic acetylcholine receptor is an important modulator of medi

187 cini preferentially expressed the muscarinic acetylcholine receptor M3 and maintained physiological r

188 Targeting acetylcholine receptor M3 prevents the progression of ai

189 pecific mechanisms of alpha3beta4*-nicotinic acetylcholine receptor modulation by the prototoxin lynx

190 ed TGFBR2 and the nicotinic antiinflammatory acetylcholine receptor nAChRa7 as murine and human miR-2

191 dependence and stimulation of the nicotinic acetylcholine receptor on the ability to interpret valen

192 a presynaptic inhibition of alpha7-nicotinic acetylcholine receptor signaling.

193 igra pars reticulata (SNr) act on muscarinic acetylcholine receptor subtype 4 (M4) to oppose cAMP-dep

194 in (MyoG), Hdac4, Ampd3, Trim63 (MuRF1), and acetylcholine receptor subunit alpha1 (Chrna1).

195 h ion channels of the ligand-gated nicotinic acetylcholine receptor superfamily (namely alpha-amino-3

196 In PAH RV samples, alpha-7 nicotinic acetylcholine receptor was increased and acetylcholinest

197 Expression of nicotinic (alpha-7 nicotinic acetylcholine receptor) and muscarinic (muscarinic acety

198 -inflammatory alpha7-nAChR (alpha7-nicotinic acetylcholine receptor) was similar in young SHR and WKY

199 The alpha7 nicotinic acetylcholine receptor, encoded by the CHRNA7 gene, has

200 acetylcholine-gated channel and a muscarinic acetylcholine receptor, respectively.

201 probe the ion channel pore of the nicotinic acetylcholine receptor, which is a prototypical Cys-loop

202 ll types expressing alpha8 subunit nicotinic acetylcholine receptor, while SPO and cOv are characteri

203 SS), or secondhand smoke, promoted nicotinic acetylcholine receptor-dependent exacerbation of AA and

204 ntiinflammatory effects via alpha7 nicotinic acetylcholine receptor-expressing splenic macrophages.

205 elicit protean agonism at the muscarinic M2 acetylcholine receptor.

206 ) and elevated circulating concentrations of acetylcholine-receptor antibody.

207 d protein, is required for the clustering of acetylcholine receptors (AChRs) at synaptic sites betwee

208 We used mutations to construct endplate acetylcholine receptors (AChRs) having only one function

209 ing the timing of expression of postsynaptic acetylcholine receptors (AChRs) impacts presynaptic rele

210 for the proper distribution of extrasynaptic acetylcholine receptors (AChRs) in Caenorhabditis elegan

211 BLA principal neurons through activation of acetylcholine receptors (AChRs), (2) enhances glutamater

212 mechanism that regulates the distribution of acetylcholine receptors (AChRs).

213 and beta4-subunit-containing human nicotinic acetylcholine receptors (alpha3beta4*-nAChRs).

214 lted from local blockade of alpha7-nicotinic acetylcholine receptors (alpha7nAChR).

215 ation of neural signals and alpha7 nicotinic acetylcholine receptors (alpha7nAChRs) on splenic macrop

216 onsmokers following stimulation of nicotinic acetylcholine receptors (familywise error-corrected P <

217 itulated with blockade of M1-type muscarinic acetylcholine receptors (M1-AChR); however, the cellular

218 with beta-arrestin binding to M1 muscarinic acetylcholine receptors (M1Rs) in two different binding

219 ulation and synaptic clustering of nicotinic acetylcholine receptors (nAChR) during neurotrophic fact

220 sociations between variants in the nicotinic acetylcholine receptors (nAChR) subunits and nicotine de

221 Nicotinic acetylcholine receptors (nAChRs) and gamma-aminobutyric

222 Neuronal nicotinic acetylcholine receptors (nAChRs) are promising drug targ

223 alpha7 nicotinic acetylcholine receptors (nAChRs) are ubiquitous in the n

224 Nicotinic acetylcholine receptors (nAChRs) assemble in the endopla

225 Nicotinic acetylcholine receptors (nAChRs) belong to the family of

226 ficant cholinergic innervation and nicotinic acetylcholine receptors (nAChRs) contribute greatly to t

227 t widely co-abused substances, and nicotinic acetylcholine receptors (nAChRs) contribute to the behav

228 hances nicotine-induced changes in nicotinic acetylcholine receptors (nAChRs) expressed on midbrain D

229 d shows high binding affinity with nicotinic acetylcholine receptors (nAChRs) expressed on the surfac

230 Antagonists of alpha9alpha10 nicotinic acetylcholine receptors (nAChRs) have been proposed as a

231 a suggest a complex interaction of nicotinic acetylcholine receptors (nAChRs) in regulating vestibula

232 KEY POINTS: Neuronal nicotinic acetylcholine receptors (nAChRs) play a fundamental role

233 Blocking beta2 or alpha7 nicotinic acetylcholine receptors (nAChRs) prevents, respectively,

234 but very little is known about how nicotinic acetylcholine receptors (nAChRs) regulate LHb activity.

235 ression and clustering of neuronal nicotinic acetylcholine receptors (nAChRs) remain poorly defined.

236 t of aging on presynaptic neuronal nicotinic acetylcholine receptors (nAChRs) within the circuitry of

237 actions through a family of brain nicotinic acetylcholine receptors (nAChRs).

238 w that endogenous Galphaq-coupled muscarinic acetylcholine receptors activate PKA.

239 Using alpha4beta2 nicotinic acetylcholine receptors and the alpha4beta2-selective po

240 Nicotinic acetylcholine receptors are ligand-gated ion channels th

241 Nicotinic acetylcholine receptors can be assembled from either hom

242 Acetylcholine receptors comprising alpha4 and beta2 subu

243 This work suggests that overstimulation of acetylcholine receptors could disrupt neuronal processin

244 myoblast differentiation and aggregation of acetylcholine receptors for the establishment of neuromu

245 rons receive cholinergic input via nicotinic acetylcholine receptors from the Kenyon cells; knocking

246 predict alcohol, and suggest that nicotinic acetylcholine receptors in the NAc are critical for this

247 rug scopolamine was used to block muscarinic acetylcholine receptors involved in working memory.

248 ivation of 42 genes, including the nicotinic acetylcholine receptors nAChRalpha1 and nAChRalpha3, in

249 Up-regulation of nicotinic acetylcholine receptors normalized before day 4 followin

250 nd acute effects of stimulation of nicotinic acetylcholine receptors on behavioral and neural signatu

251 r in animals through inhibition of nicotinic acetylcholine receptors present in the central nervous s

252 h can also activate, potentiate, and inhibit acetylcholine receptors, including neuronal nicotinic re

253 ies conducted on the extracellular domain of acetylcholine receptors, ion channels from prokaryote ho

254 strategy is to selectively target muscarinic acetylcholine receptors, particularly the M1 muscarinic

255 species from all five subtypes of muscarinic acetylcholine receptors, suggesting allosteric binding.

256 line acting on both nicotinic and muscarinic acetylcholine receptors.

257 responses that result from poorly clustered acetylcholine receptors.

258 eting the cannabinoid 1 and alpha7 nicotinic acetylcholine receptors.

259 an be rescued by an antagonist of muscarinic acetylcholine receptors.

260 tein-coupled receptors, including muscarinic acetylcholine receptors.

261 recruited nerves drive cancer growth through acetylcholine-regulated Wnt signaling and stimulation of

262 est the relationship between novelty-induced acetylcholine release and later contextual associability

263 rdings revealed that the high probability of acetylcholine release at these synapses allowed muscarin

264 These results demonstrate that acetylcholine release can cause slow inhibition of princ

265 These results indicate that acetylcholine release coordinates neural oscillations du

266 in prefrontal network synchrony modulated by acetylcholine release during cue detection.

267 Rhythmic neural activity and increases in acetylcholine release in the prefrontal cortex contribut

268 with shock, suggesting that novelty-induced acetylcholine release primes future contextual associati

269 ease, suggesting that feedback inhibition of acetylcholine release was not involved.

270 t system, via phasic increases in prefrontal acetylcholine release, plays an essential role in attent

271 ical methods, we demonstrate that cue-evoked acetylcholine release, through distinct actions at both

272 st confirmed that detected cues evoke phasic acetylcholine release.

273 ction is thought to be primarily mediated by acetylcholine released from cholinergic interneurons (Ch

274 nses after inhibition of NO synthase blunted acetylcholine responses in KK and lean controls, but had

275 n of the rabies virus glycoprotein inhibited acetylcholine responses of alpha4beta2 nicotinic recepto

276 Acetylcholine responses were improved (P<0.05) with Temp

277 holinesterase (AChE), an enzyme specific for acetylcholine, resulting in AuQC@BSA-AChE.

278 sed epibatidine sensitivity but at a cost of acetylcholine sensitivity.

279 nvolved in sleep control are GABA, dopamine, acetylcholine, serotonin, and several neuropeptides.

280 nAChRs) contribute greatly to the effects of acetylcholine signaling.

281 ey also reveal distinct roles for orexin and acetylcholine signals in NAc shell for hedonic reactions

282 ilities.SIGNIFICANCE STATEMENT The nicotinic acetylcholine system plays a central role in neuromodula

283 in most insects, catalyses the breakdown of acetylcholine, thereby terminating synaptic transmission

284 ely, based on a difference in the potency of acetylcholine to activate them.

285 , reconstituted SlCAT2 showed competence for acetylcholine transport, which was also inhibited by met

286 brain sections stained for either vesicular acetylcholine transporter or choline acetyltransferase (

287 The septal cells stained for vesicular acetylcholine transporter, but not for ChAT, have enlarg

288 amicol, a SPECT radiotracer of the vesicular acetylcholine transporter, to evaluate in vivo in DLB th

289 ain sections immunostained for the vesicular acetylcholine transporter.

290 f (123)I-iodobenzovesamicol to the vesicular acetylcholine transporter.

291 No difference in muscarinic acetylcholine type 2 receptor expression was observed.

292 otinic acetylcholine receptor and muscarinic acetylcholine type 2 receptor expression, as well.

293 choline receptor) and muscarinic (muscarinic acetylcholine type 2 receptor) receptors, and acetylchol

294 We found that acetylcholine upregulated the PCTR biosynthetic pathway

295 Venular dilatation to acetylcholine was blunted in OZR vs. LZR due to increase

296 o the organic cations Tetraethylammonium and Acetylcholine were transported indicating involvement of

297 nted endothelium-dependent vasorelaxation to acetylcholine, which was normalized by a specific Nox2 N

298 nted endothelium-dependent vasorelaxation to acetylcholine, which was normalized by a specific Nox2 N

299 Female patients were more sensitive to acetylcholine with vasomotor dysfunction occurring at lo

300 ), l-aspartate, gamma-aminobutyric acid, and acetylcholine, with l-Glu eliciting the highest increase