ライフサイエンスコーパス: acetylglucosamine

1 idic linkages of N-acetylgalactosamine and N-acetylglucosamine.

2 ic reactions involving uridine diphosphate N-acetylglucosamine.

3 (OGT) modifies intracellular proteins with N-acetylglucosamine.

4 ose, alpha-glucose, beta-glucose, and beta-N-acetylglucosamine.

5 instantaneous reaction with substrate UDP-N-acetylglucosamine.

6 increased binding capacity of ficolin-2 to N-acetylglucosamine.

7 ucosamine (neosamine) series prepared from N-acetylglucosamine.

8 well as UDP-N-acetylgalactosamine and UDP-N-acetylglucosamine.

9 lipoprotein YceK, toxin HicA, or MurA (UDP-N-acetylglucosamine 1-carboxyvinyltransferase) suppressed

10 tic identified two signaling muropeptides (N-acetylglucosamine-1,6-anhydro-N-acetylmuramyl pentapepti

11 DP-GlcNAc biosynthesis, converting UTP and N-acetylglucosamine-1-phosphate (GlcNAc-1P) to UDP-GlcNAc.

12 Eight N-acetylglucosamine-1-phosphate and N-acetylgalactosamine-

13 struction of a defined mutation in the UDP-N-acetylglucosamine-1-phosphate transferase gene, wecA, in

14 struction of a defined mutation in the UDP-N-acetylglucosamine-1-phosphate transferase gene, wecA, in

15 al and chemoenzymatic syntheses relying on N-acetylglucosamine-1-phosphate uridylyltransferase (GlmU)

16 n the mammalian transmembrane glycoprotein N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosa

17 UDP-GlcNAc:lysosomal enzyme N-acetylglucosamine-1-phosphotransferase (GlcNAc-1-phospho

18 he Golgi enzyme UDP-GlcNAc:lysosomal enzymeN-acetylglucosamine-1-phosphotransferase (GlcNAc-1-phospho

19 ta subunits of UDP-GlcNAc:lysosomal enzyme N-acetylglucosamine-1-phosphotransferase (phosphotransfera

20 The Golgi-resident N-acetylglucosamine-1-phosphotransferase (PT) complex is c

21 ineered to carry a mutation in the Gnptab (N-acetylglucosamine-1-phosphotransferase subunits alpha/be

22 sosomal storage disorder caused by loss of N-acetylglucosamine-1-phosphotransferase, which tags lysos

23 hosphate uridylyltransferase (galU), a UDP-N-acetylglucosamine 2-epimerase (wecB) and a UDP-N-acetyl-

24 protein with key enzymatic activities, UDP-N-acetylglucosamine 2-epimerase and N-acetylmannosamine ki

25 Using UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase

26 he key enzyme of sialic acid biosynthesis, N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase

27 paucimannosylation (mannose(1-3)fucose(0-1)N-acetylglucosamine(2)Asn).

28 sis of sialic acid is the bifunctional UDP-N-acetylglucosamine-2-epimerase/N-acetylmannosamine kinase

29 etylmannosamine kinase (MNK) domain of UDP-N-acetylglucosamine-2-epimerase/N-acetylmannosamine kinase

30 e (UDP)-sugar donors, UDP-4-deoxy-4-fluoro-N-acetylglucosamine (4FGlcNAc) and UDP-4-deoxy-4-fluoro-N-

31 Sulf1 codes for an N-acetylglucosamine 6-O-endosulfatase, an enzyme that spec

32 Mice deficient in N-acetylglucosamine-6-O-sulfotransferase-1 (GlcNAc6ST-1) f

33 clear cells and identified 2 autoantigens, N-acetylglucosamine-6-sulfatase (GNS) and filamin A (FLNA)

34 Uridine diphospho-N-acetylglucosamine, a product of the hexosamine synthetic

35 UDP-N-acetylglucosamine acyltransferase (LpxA) and UDP-3-O-(ac

36 UDP-N-acetylglucosamine acyltransferase (LpxA) and UDP-3-O-(R-

37 ase of the structures containing bisecting N-acetylglucosamine along with bi- and trisialylated trian

38 t resulting in IgG molecules with only one N-acetylglucosamine and a fucose residue was fully able to

39 the C6 and C1 hydroxyl groups of mannose, N-acetylglucosamine and glucose respectively.

40 in a ligand-free form, in complex with the N-acetylglucosamine and N-acetylgalactosamine products of

41 These structures showed N-acetylglucosamine and N-acetylgalactosamine to be recogn

42 to catalyze the in vitro incorporation of N-acetylglucosamine and N-acetylgalactosamine to oligosacc

43 tion-dependent manner and was inhibited by N-acetylglucosamine and N-acetylgalactosamine.

44 ypical M. xanthus lipids, fucose, mannose, N-acetylglucosamine and N-acetylgalactoseamine carbohydrat

45 e glycosylation form, with high amounts of N-acetylglucosamine and sialic acid.

46 ll producing an identical polymer from UDP-N-acetylglucosamine and UDP-glucuronic acid.

47 2 able to utilize both uridine diphosphate N-acetylglucosamine and uridine diphosphate N-acetylgalact

48 cell wall precursors, UDP-Glucose and UDP-N-acetylglucosamine are efficiently used to initiate trans

49 ne O-GlcNAcylation (O-GlcNAc=O-linked beta-N-acetylglucosamine) are largely unexplored.

50 se cytoplasmic UDP-glucuronic acid and UDP-N-acetylglucosamine as substrates.

51 successive coupled enzyme assays using UDP-n-acetylglucosamine as the initial sugar substrate.

52 Similar to alginate and poly-beta-1,6 N-acetylglucosamine, bacterial cellulose is implicated in

53 fer of GalNAc to the simple sugar acceptor N-acetylglucosamine-beta-p-nitrophenol (GlcNAcbeta-pNP) is

54 trisaccharide [N-acetylgalactosamine-beta3-N-acetylglucosamine-beta4-(phosphate-6-)mannose] is requir

55 to the GalFuc-binding lectin CGL2 and the N-acetylglucosamine-binding lectin XCL, the mutant was res

56 agellar and type III secretion systems and N-acetylglucosamine-binding protein GpbA while inducing ge

57 embrane protein, as well as spermidine and N-acetylglucosamine biosynthesis, all contribute to surami

58 utation using both the UDP-glucose and UDP-N-acetylglucosamine bound structures of the wild-type prot

59 tor endocytosis and signaling by promoting N-acetylglucosamine branching of Asn (N)-linked glycans.

60 of uridyldiphospho-3-O-(R-hydroxydecanoyl)-N-acetylglucosamine by the enzyme LpxC.

61 A fluoro-tagged N-acetylglucosamine-capped glycolipid that can form lipid

62 for receptor function, and elongation with N-acetylglucosamine, catalyzed by members of the Fringe fa

63 Inhibition of hexokinase by N-acetylglucosamine causes its dissociation from mitochond

64 easured by the incorporation of the [(14)C]N-acetylglucosamine cell wall precursor.

65 et al. (2016) report that detection of the N-acetylglucosamine component of peptidoglycan by the glyc

66 le the UT-A1 in lipid rafts was the mature N-acetylglucosamine-containing form, as detected by wheat

67 ns confer recognitional specificity toward N-acetylglucosamine-containing signaling molecules, such a

68 Exposure to bacteria or their N-acetylglucosamine-containing surface polysaccharides, in

69 nhibitor of UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase (LpxC) in Gram-negative ba

70 mined and found to be a member of the PIG-LN-acetylglucosamine deacetylase family; GalB is structural

71 made of repeating N-acetylmuramic acid and N-acetylglucosamine disaccharides cross-linked by pentapep

72 synthetic pathway (HBSP) that produces UDP-N-acetylglucosamine for O-linked N-acetylglucosamine modif

73 OGT catalyses the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine (UDP-GlcN

74 e pools of UDP-glucose, UDP-galactose, UDP-N-acetylglucosamine, GDP-mannose, and GDP-fucose in Plasmo

75 hase 1-3 (HAS1-3) isoenzymes that transfer N-acetylglucosamine (GlcNAc) and glucuronic acid (GlcUA) i

76 sugar-aromatic interactions, with glucose, N-acetylglucosamine (GlcNAc) and mannose in between.

77 lycan (PGN) consists of repeating units of N-acetylglucosamine (GlcNAc) and N-acetylmuramic acid (Mur

78 on of nucleocytoplasmic proteins with beta-N-acetylglucosamine (GlcNAc) and regulates numerous biolog

79 particular with higher levels of beta-1,6-N-acetylglucosamine (GlcNAc) branched N-glycans.

80 on is altered by deleting two Bdellovibrio N-acetylglucosamine (GlcNAc) deacetylases, one of which we

81 The sugar N-acetylglucosamine (GlcNAc) enhances N-glycan branching a

82 N-acetylglucosamine (GlcNAc) exists ubiquitously as a comp

83 ate addition and removal, respectively, of N-acetylglucosamine (GlcNAc) from intracellular protein su

84 -GlcNAc transferase (OGT), which transfers N-acetylglucosamine (GlcNAc) from the nucleotide sugar don

85 outstanding affinities for derivatives of N-acetylglucosamine (GlcNAc) in aqueous solution.

86 (OGT) mediates post-translational O-linked N-acetylglucosamine (GlcNAc) modification.

87 usly that varphi11 requires alpha- or beta-N-acetylglucosamine (GlcNAc) moieties on cell wall teichoi

88 ase that mediates the O-linked addition of N-acetylglucosamine (GlcNAc) moieties to Ser and Thr resid

89 proteins via O-linked addition of a single N-acetylglucosamine (GlcNAc) moiety.

90 scribed here, is attached to the remaining N-acetylglucosamine (GlcNAc) of IgG, using a mutant endogl

91 To study the effect of short N-acetylglucosamine (GlcNAc) oligosaccharides on the physi

92 Dynamic cycling of N-Acetylglucosamine (GlcNAc) on serine and threonine resid

93 ide variety of substrates which contain an N-acetylglucosamine (GlcNAc) residue to act as an 'accepto

94 ranslationally modified by adding O-linked N-acetylglucosamine (GlcNAc) residue to serine or threonin

95 dules recognize polysaccharides containing N-acetylglucosamine (GlcNAc) residues including peptidogly

96 reducing end glucose of CPS and the beta-D-N-acetylglucosamine (GlcNAc) residues of peptidoglycan (PG

97 Chitin, a homopolymer of beta1,4-linked N-acetylglucosamine (GlcNAc) residues, is a key component

98 lyrhamnose backbone with an immunodominant N-acetylglucosamine (GlcNAc) side chain, which is the basi

99 d consists of a polyrhamnose polymer, with N-acetylglucosamine (GlcNAc) side chains, which is an esse

100 MX regulates formation of N-acetylglucosamine (GlcNAc) terminated N-glycans that par

101 core-2 O-glycan branch through addition of N-acetylglucosamine (GlcNAc) to a core-1 O-glycan structur

102 c Fringe) and MFNG (Manic Fringe) transfer N-acetylglucosamine (GlcNAc) to O-fucose attached to EGF-l

103 The transfer of N-acetylglucosamine (GlcNAc) to Ser or Thr in cytoplasmic

104 odifies protein function by attaching beta-N-acetylglucosamine (GlcNAc) to serine and threonine resid

105 ions of PgaB show a binding preference for N-acetylglucosamine (GlcNAc) to the N-terminal domain and

106 O-linked N-acetylglucosamine (GlcNAc) transferase (OGT) is the only

107 Here, we show that O-linked N-acetylglucosamine (GlcNAc) transferase (OGT), an enzyme

108 nctional homologue of the Candida albicans N-acetylglucosamine (GlcNAc) transporter NGT1, and represe

109 e for glycolysis and chitobiose to produce N-acetylglucosamine (GlcNAc), a key component of the bacte

110 ibed to contain the sugars rhamnose (Rha), N-acetylglucosamine (GlcNAc), galactose (Gal), xylose (Xyl

111 Various stimuli, including N-acetylglucosamine (GlcNAc), induce the fungal pathogen C

112 hesis of a tetra-antennary glycan that has N-acetylglucosamine (GlcNAc), N-acetyllactosamine (LacNAc)

113 entation of culture media with uridine and N-acetylglucosamine (GlcNAc), precursors for the hexosamin

114 nslational modification with O-linked beta-N-acetylglucosamine (GlcNAc), promoted apoptosis through a

115 to form hyphae in response to the inducer N-acetylglucosamine (GlcNAc), suggesting that a basal leve

116 death domain-containing host proteins with N-acetylglucosamine (GlcNAc), thereby blocking extrinsic a

117 ry glycan [A3(2,4,2) type] terminated with N-acetylglucosamine (GlcNAc), which is generated by N-acet

118 rom the cheaper and commercially available N-acetylglucosamine (GlcNAc).

119 are mainly composed of virally synthesized N-acetylglucosamine (GlcNAc).

120 results of many cysteine residues bound to N-acetylglucosamine (GlcNAc).

121 n, demonstrating that the 6-O-sulfation of N-acetylglucosamine (GlcNAc-6-O-sulfation) is highly conse

122 glycan precursor [glucose(Glc)](3)(Man)(9)[N-acetylglucosamine(GlcNAc)](2).

123 is functionally modified by O-linked beta-N-acetylglucosamine glycosylation (O-GlcNAcylation).

124 is the presence of a nonreducing terminal N-acetylglucosamine; however, this residue is normally abs

125 amine transferase (OGT), and O-linked beta-N-acetylglucosamine hydrolase in control and IPAH cells an

126 ial cells as demonstrated by inhibition of N-acetylglucosamine incorporation into polymeric cell wall

127 In H. jecorina-produced HjCel3A, a single N-acetylglucosamine is present at both sites, whereas in P

128 Also, N-acetylglucosamine is selectively oxidized at C3.

129 Chitin, a biopolymer of N-acetylglucosamine, is abundant in invertebrates and fung

130 on of chitin, a beta-1,4 linked polymer of N-acetylglucosamine, is of major interest in areas varying

131 Specificity studies with human N-acetylglucosamine kinase and hexokinase IV indicated a h

132 es residues that are already modified with N-acetylglucosamine, likely by converting into a relaxed c

133 O-linked N-acetylglucosamine linkage (O-GlcNAcylation) to serine or

134 osphate-N-acetylmuramic acid(pentapeptide)-N-acetylglucosamine (lipid II), which is readily accessibl

135 for a unique phosphotransferase system and N-acetylglucosamine metabolism suggests an important ecolo

136 duces UDP-N-acetylglucosamine for O-linked N-acetylglucosamine modification (O-GlcNAcylation) of prot

137 ed by cAMP (EPAC), involving also O-linked N-acetylglucosamine modification downstream of the hexosam

138 s resulted in reduced global O-linked beta-N-acetylglucosamine modification levels and abrogated PASM

139 We measured the levels of O-linked beta-N-acetylglucosamine modification, O-linked beta-N-acetylgl

140 iosynthetic pathway, which allows O-linked N-acetylglucosamine modifications of proteins.

141 he addition of the phosphothreonine to the N-acetylglucosamine moiety and CD0243 transfers the methyl

142 ongest interactions are established by the N-acetylglucosamine moiety in the central region of the en

143 omposed of N-acetylmuramic acid-(beta-1,4)-N-acetylglucosamine (MurNAc-GlcNAc) disaccharides associat

144 g amino sugars [i.e., N-acetylmuramic acid-N-acetylglucosamine (MurNAc-GlcNAc)] from attached peptido

145 enzymes phosphomannomutase (PMM), phospho-N-acetylglucosamine mutase (PAGM) and phosphoglucomutase (

146 s was reduced by selective inactivation of N-acetylglucosamine N-deacetylase-N-sulfotransferase (Ndst

147 uniform responses (d-lactose, d-galactose, N-acetylglucosamine, N-acetylneuraminic acid), 'all-or-non

148 tility, decreased chemotactic responses to N-acetylglucosamine (NAG) and attenuated ability to dissem

149 g azides and alkynes were installed on tri-N-acetylglucosamine (NAG)3, a PG mimic, as well as PG isol

150 onal addition and removal of O-linked beta-N-acetylglucosamine (O-GlcNAc) also occurs on serine resid

151 signaling pathway, terminating in O-linked-N-acetylglucosamine (O-GlcNAc) cycling, is a key sensor of

152 O-linked beta-N-acetylglucosamine (O-GlcNAc) glycosylation is a regulato

153 ion controlled by the enzyme O-linked-beta-N-acetylglucosamine (O-GlcNAc) glycosyltransferase as comp

154 ar and cytosolic proteins by O-linked beta-N-acetylglucosamine (O-GlcNAc) has been shown to play an i

155 O-Linked beta-N-acetylglucosamine (O-GlcNAc) is a carbohydrate post-tran

156 O-Linked beta-N-acetylglucosamine (O-GlcNAc) is a post-translational mod

157 O-linked N-acetylglucosamine (O-GlcNAc) is a post-translational mod

158 ational protein modification O-linked beta-N-acetylglucosamine (O-GlcNAc) is a proposed nutrient sens

159 O-linked N-acetylglucosamine (O-GlcNAc) is a reversible posttransla

160 O-linked beta-N-acetylglucosamine (O-GlcNAc) is a reversible posttransla

161 Glycosylation with O-linked beta-N-acetylglucosamine (O-GlcNAc) is one of the protein glyco

162 Cellular O-linked N-acetylglucosamine (O-GlcNAc) levels are modulated by two

163 O-Linked beta-N-acetylglucosamine (O-GlcNAc) modification found on the s

164 We studied O-linked beta-N-acetylglucosamine (O-GlcNAc) modification of contractile

165 O-linked beta-N-acetylglucosamine (O-GlcNAc) modification of cytoplasmic

166 efute the hypothesis of extensive O-linked N-acetylglucosamine (O-GlcNAc) modification of endogenous

167 Although the O-linked N-acetylglucosamine (O-GlcNAc) modification of the RNA pol

168 O-linked N-acetylglucosamine (O-GlcNAc) modifications regulate the

169 how that Oct1 is modified by O-linked beta-N-acetylglucosamine (O-GlcNAc) moieties.

170 study, we show that TAB1 is modified with N-acetylglucosamine (O-GlcNAc) on a single site, Ser395.

171 osttranslational addition of O-linked beta-N-acetylglucosamine (O-GlcNAc) on intracellular proteins.

172 Dynamic cycling of O-linked beta-N-acetylglucosamine (O-GlcNAc) on nucleocytoplasmic protei

173 Evidence suggests that the O-linked N-acetylglucosamine (O-GlcNAc) posttranslational modificat

174 is study, we demonstrate that the O-linked N-acetylglucosamine (O-GlcNAc) processing enzymes, O-GlcNA

175 t-translational modification O-linked beta-N-acetylglucosamine (O-GlcNAc) regulates thousands of nucl

176 ss of interest is the addition of O-linked N-acetylglucosamine (O-GlcNAc) residues onto nuclear and c

177 the covalent addition of an O-linked beta-N-acetylglucosamine (O-GlcNAc) sugar moiety to hydroxyl gr

178 ed, in part, by the attachment of O-linked N-acetylglucosamine (O-GlcNAc) to proteins (O-GlcNAcylatio

179 e reversibly glycosylated by O-linked beta-N-acetylglucosamine (O-GlcNAc) to regulate their function,

180 ational addition of a single O-linked beta-N-acetylglucosamine (O-GlcNAc) to serine or threonine resi

181 st-translational addition of O-linked beta-N-acetylglucosamine (O-GlcNAc) to various nuclear and cyto

182 O-linked N-acetylglucosamine (O-GlcNAc) transferase (OGT) is an ess

183 Here we demonstrate that O-linked beta-N-acetylglucosamine (O-GlcNAc) transferase (OGT) is requir

184 The nutrient sensor O-linked-beta-N-acetylglucosamine (O-GlcNAc) transferase (OGT) modifies

185 N-Acetylglucosamine (O-GlcNAc) transferase (OGT) regulates

186 w that DELLAs are modified by the O-linked N-acetylglucosamine (O-GlcNAc) transferase (OGT) SECRET AG

187 ine biosynthesis pathway and O-linked beta-N-acetylglucosamine (O-GlcNAc) transferase (OGT) to potent

188 TET2 and TET3 associate with O-linked beta-N-acetylglucosamine (O-GlcNAc) transferase (OGT), an enzym

189 We identifed O-linked-N-acetylglucosamine (O-GlcNAc) transferase (OGT), an X-lin

190 AMPK directly phosphorylates O-linked beta-N-acetylglucosamine (O-GlcNAc) transferase (OGT).

191 t-responsive glycosyltransferase, O-linked N-acetylglucosamine (O-GlcNAc) transferase (OGT).

192 We demonstrate that O-linked N-acetylglucosamine (O-GlcNAc), a post-translational modif

193 One such signal, O-linked beta-N-acetylglucosamine (O-GlcNAc), is an essential post-trans

194 h a modification in the amount of O-linked N-acetylglucosamine (O-GlcNAc)-modified proteins and in th

195 ovalent modification of CaMKII by O-linked N-acetylglucosamine (O-GlcNAc).

196 olic and nuclear proteins by O-linked beta-N-acetylglucosamine (O-GlcNAc).

197 oteins by monosaccharides of O-linked beta-N-acetylglucosamine (O-GlcNAc).

198 uclear and cytoplasmic protein by O-linked N-acetylglucosamine (O-GlcNAc).

199 n of serine/threonine residues by O-linked N-acetylglucosamine (O-GlcNAc).

200 modification of proteins by O-linked beta-N-acetylglucosamine (O-GlcNAcylation) is a key metabolic r

201 ty and protein glycosylation with O-linked N-acetylglucosamine (O-GlcNAcylation) on HA and chondroiti

202 modification of proteins with beta-linked N-acetylglucosamine (O-GlcNAcylation) via overexpression o

203 eased modification of proteins by O-linked N-acetylglucosamine (O-GlcNAcylation).

204 de beta-N-acetylmuramic acid, (1-->4)-beta-N-acetylglucosamine of staphylococcal peptidoglycan.

205 ween the aromatic side chain and the first N-acetylglucosamine of the glycan.

206 ation, sialylation, and level of bisecting N-acetylglucosamine of the IgG glycans.

207 fy the pattern of O-glycosylation (21 mono-N-acetylglucosamines) of its AST domain.

208 mmatory and stress responses, and O-linked N-acetylglucosamine (OGN) transferase (OGT), an enzyme tha

209 he reaction of free MurA and substrate UDP-N-acetylglucosamine or isomer UDP-N-acetylgalactosamine.

210 hydrolyze the beta-linkages joining either N-acetylglucosamine or N-acetylgalactosamine to a wide var

211 O-Linked beta-N-acetylglucosamine, or O-GlcNAc, is a dynamic post-transl

212 ubstrates (a mix of substrates, glutamine, N-acetylglucosamine, or pyruvate) revealed contrasting cap

213 us route of infection due to poly-beta-1,6-N-acetylglucosamine overproduction.

214 lly predicted putative miR-185 targets UDP-N-acetylglucosamine-peptide N-acetylglucosaminyltransferas

215 ct O antigen, a capsule mutant, and a poly-N-acetylglucosamine (PGA) mutant.

216 ysaccharide intercellular adhesin, or poly N-acetylglucosamine (PIA/PNAG).

217 Poly-N-acetylglucosamine (PNAG) is a major component of the Sta

218 conserved cell surface polysaccharide poly-N-acetylglucosamine (PNAG) were effective at mediating red

219 encoding the biosynthesis of poly-beta-1,6-N-acetylglucosamine (PNAG), a major biofilm matrix compone

220 isolate and found to be negative for poly-N-acetylglucosamine (PNAG)-like material by immunoblot ass

221 adly expressed microbial carbohydrate poly-N-acetylglucosamine (PNAG).

222 Two intracellular enzymes, UDP-N-acetylglucosamine-polypeptide beta-N-acetylglucosaminyl

223 se O-GlcNAc transferase (uridine diphospho-N-acetylglucosamine:polypeptide beta-N-acetylaminyltransfe

224 UDP-N-acetylglucosamine pyrophosphorylase (UAP) is the final e

225 mmy codes for the single UDP-N-acetylglucosamine pyrophosphorylase in Drosophila, and i

226 FGFR1c2 can tolerate an HS chain having an N-acetylglucosamine residue at its non-reducing end.

227 d to the proximal (reducing-terminal) core N-acetylglucosamine residue of N-glycans by beta1,4-linked

228 lpha1,3 moiety attached to the distal core N-acetylglucosamine residue was detected.

229 tode glycan cores, specifically the distal N-acetylglucosamine residue; this result is in accordance

230 glycan structure of seven mannosyl and two N-acetylglucosamine residues (Man7GlcNAc2) on misfolded gl

231 linear tetrasaccharide that contained two N-acetylglucosamine residues and a free OH group gave two

232 Cnm and strongly suggested the presence of N-acetylglucosamine residues attached to Cnm.

233 ves the attachment of single beta-O-linked N-acetylglucosamine residues to serine and threonine resid

234 nds between N-acetylmuramic acid (NAM) and N-acetylglucosamine residues with concomitant formation of

235 O-fucosyl or 6-O-sulfo substituents in the N-acetylglucosamine residues.

236 lus niger in deglycosylated and Asn-linked N-acetylglucosamine-stub forms reveal a 10(2/3)-turn paral

237 magnetic resonance and shown to contain an N-acetylglucosamine substituted with a phosphorylated N-me

238 e for the selective phosphorylation of the N-acetylglucosamine sugar in a teicoplanin A2-2 derivative

239 dynamically modified with an O-linked beta-N-acetylglucosamine sugar in response to hypoxia.

240 The enzymatic addition of a single beta-D-N-acetylglucosamine sugar molecule on serine and/or threon

241 ion consisting of the addition of a single N-acetylglucosamine sugar to serine and threonine residues

242 ated post-translational addition of beta-D-N-acetylglucosamine sugars to nuclear and cytoplasmic prot

243 vidently, hexosamine pathway activation or N-acetylglucosamine supplementation induces distinct prote

244 control of HmsHFRS-dependent poly-beta-1,6-N-acetylglucosamine synthesis.

245 The dynamic cycling of N-acetylglucosamine (termed O-GlcNAcylation) on serine or

246 idue is in closer proximity (7.6 A) to the N-acetylglucosamine than the two other sugar rings present

247 Chitin is a polymer of N-acetylglucosamine that is abundant and widely found in t

248 mmasome activation is caused by release of N-acetylglucosamine that is detected in the cytosol by the

249 tic itineraries for other sugars; for beta-N-acetylglucosamine, the key N-acetyl arm confounds the pu

250 These results demonstrate that glucose and N-acetylglucosamine, the most readily available chiral bui

251 K3, which is essential for the transfer of N-acetylglucosamine to arginine residues (arginine-GlcNAcy

252 Sf-GNT-I transferred N-acetylglucosamine to Man(5)GlcNAc(2), Man(3)GlcNAc(2), a

253 Sf-GNT-II only transferred N-acetylglucosamine to Man(alpha1-6)[GlcNAc(beta1-2)Man(al

254 etylmannosamine kinase that transforms UDP-N-acetylglucosamine to N-acetylmannosamine (ManNAc) follow

255 Fringe enzymes add N-acetylglucosamine to O-fucose and modify Notch signaling

256 such modification is addition of O-linked N-acetylglucosamine to serine or threonine residues, known

257 dification involving the O-linkage of beta-N-acetylglucosamine to serine/threonine residues of membra

258 Addition of the N-glycan precursor N-acetylglucosamine to the growth medium slows aging in wi

259 nctions as a ligase that adds the terminal N-acetylglucosamine to the lipooligosaccharide core of Y.

260 e essential mammalian enzyme O-linked beta-N-acetylglucosamine transferase (O-GlcNAc transferase, her

261 involved in cell metabolism: O-linked beta-N-acetylglucosamine transferase (OGT) and isocitrate dehyd

262 O-Linked N-acetylglucosamine transferase (OGT) catalyzes O-GlcNAcyl

263 O-Linked beta-N-acetylglucosamine transferase (OGT) is an essential huma

264 O-linked N-acetylglucosamine transferase (OGT) is found in all meta

265 umors from colon tumor cells with O-linked N-acetylglucosamine transferase (OGT) knockdown grew signi

266 tylglucosamine modification, O-linked beta-N-acetylglucosamine transferase (OGT), and O-linked beta-N

267 with host cell factor-1 (HCF-1), O-linked N-acetylglucosamine transferase (OGT), and the polycomb gr

268 es in proteins by the enzyme O-linked beta-N-acetylglucosamine transferase (OGT), whereas the enzyme

269 s an essential substrate for O-linked beta-N-acetylglucosamine transferase (OGT), which glycosylates

270 s a putative serine and threonine O-linked N-acetylglucosamine transferase (OGT).

271 also interacts with the O-GlcNAc (O-linked N-acetylglucosamine) transferase SPINDLY required for prop

272 LPH3 supports incorporation of both core 2 N-acetylglucosamine-transferase 1 and alpha-2,6-sialyltran

273 o control the Golgi localization of core 2 N-acetylglucosamine-transferase 1.

274 hat EXTL2 exhibited much stronger in vitro N-acetylglucosamine-transferase activity related to elonga

275 SLC35A3 is considered the main UDP-N-acetylglucosamine transporter (NGT) in mammals.

276 lactose transporter (UGT; SLC35A2) and UDP-N-acetylglucosamine transporter (NGT; SLC35A3) form hetero

277 000) as an ER-localized facilitator of UDP-N-acetylglucosamine (UDP-GlcNAc) and UDP-N-acetylgalactosa

278 we show that TpeL preferably utilizes UDP-N-acetylglucosamine (UDP-GlcNAc) as a sugar donor.

279 osamine biosynthetic pathway, increase UDP-N-acetylglucosamine (UDP-GlcNAc) availability, and lead to

280 thatlymphostatin binds uridine diphosphate-N-acetylglucosamine (UDP-GlcNAc) but not UDP-glucose (UDP-

281 athway (HBP) generates uridine diphosphate N-acetylglucosamine (UDP-GlcNAc) for glycan synthesis and

282 The sugar nucleotide UDP-N-acetylglucosamine (UDP-GlcNAc) is an essential metabolit

283 Uridine 5'-diphosphate-N-acetylglucosamine (UDP-GlcNAc) is the donor sugar substr

284 The HBP end product UDP-N-acetylglucosamine (UDP-GlcNAc) is used in enzymatic post

285 kingly, addition of the HBP metabolite UDP-N-acetylglucosamine (UDP-GlcNAc) to CRPC-like cells signif

286 e transfer of N-acetylglucosamine from UDP-N-acetylglucosamine (UDP-GlcNAc) to serines and threonines

287 ntracellular levels of uridine diphosphate-N-acetylglucosamine (UDP-GlcNAc), a key precursor of LacNA

288 mine are precursors of uridine diphosphate N-acetylglucosamine (UDP-GlcNAc), a substrate for cellular

289 iosynthesis precursor, uridine diphosphate N-acetylglucosamine (UDP-GlcNAc), was monitored by recordi

290 In complex with the cosubstrate UDP-N-acetylglucosamine (UDP-GlcNAc),O-linked-GlcNAc transfera

291 way (HBP), to increase uridine diphosphate-N-acetylglucosamine (UDP-GlcNAc).

292 es UDP-glucuronic acid (UDP-GlcUA) and UDP-N-acetylglucosamine (UDP-GlcNAc).

293 lyzes the formation of uridine diphosphate-N-acetylglucosamine (UDP-GlcNAc).

294 -glucuronic acid, and UGT3 enzymes use UDP-N-acetylglucosamine, UDP-glucose, and UDP-xylose to conjug

295 , ChiA variants with weaker binding of the N-acetylglucosamine unit either in substrate-binding site

296 core alpha1,3-fucosylation of the proximal N-acetylglucosamine was abolished, the degree of galactosy

297 ties for uncharged substrates (glucose and N-acetylglucosamine) were also enhanced, despite competiti

298 ep in the synthesis of uridine diphosphate N-acetylglucosamine, which is required for the biosynthesi

299 rsion of UDP-N-acetylgalactosamine and UDP-N-acetylglucosamine while the bacterial enzyme cannot.

300 beta4 addition of N-acetylgalactosamine to N-acetylglucosamine with formation of the N,N-diacetyllact