ライフサイエンスコーパス: acetylglucosaminidase

1 N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase).

2 , BgaA, a beta-galactosidase, and StrH, an N-acetylglucosaminidase.

3 pecificity expected of the processing beta-N-acetylglucosaminidase.

4 cture used to confirm that SleL acts as an N-acetylglucosaminidase.

5 trated that ACS activity co-localized with N-acetylglucosaminidase.

6 c hydrolases, a chitodextrinase and a beta-N-acetylglucosaminidase.

7 tic transglycosylases but rather as a beta-N-acetylglucosaminidase.

8 ve cloned the cDNA and gene encoding alpha-N-acetylglucosaminidase.

9 ases but also contains a subfamily of beta-N-acetylglucosaminidases.

10 ficantly greater in the presence of beta-d-N-acetylglucosaminidase (410 +/- 60%, p < 0.01).

11 utation in the gene (NAGLU) encoding alpha-N-acetylglucosaminidase, a lysosomal enzyme required for t

12 that the satellites are the products of an N-acetylglucosaminidase activity that differs from the atl

13 genous levels of specific, processing beta-N-acetylglucosaminidase activity were significantly reduce

14 olase family associated with peptidoglycan N-acetylglucosaminidase activity, suggesting that T6S pept

15 2 as chemoattractants and inducers of beta-N-acetylglucosaminidase activity.

16 N-Acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase, also known as "uncovering" enzyme

17 ve developed an assay system for endo-beta-N-acetylglucosaminidase and glycoamidase (PNGase), using E

18 They were totally deficient in alpha-N-acetylglucosaminidase and had massive accumulation of he

19 We demonstrate that Acm2 is an N-acetylglucosaminidase and identify the pattern of O-glyc

20 GLU gene, resulting in deficiency of alpha-N-acetylglucosaminidase and lysosomal accumulation of hepa

21 beta-GlcNAc moiety by treatment with beta-N-acetylglucosaminidase and selective extension of the oth

22 ne with (Man(9)GlcNAc(2))Asn for endo-beta-N-acetylglucosaminidase and the other with Ala-Ser-Phe-(Ma

23 acid sequence comparisons, the novel beta-N-acetylglucosaminidase appears to be conserved in all 12

24 ll-separating activity of BslO, a putative N-acetylglucosaminidase bearing three N-terminal S-layer h

25 Drug inhibition of OGT and OGA (N-acetylglucosaminidase) blocked transcription during prei

26 lcNAc from proteins (peptide O-GlcNAc-beta-N-acetylglucosaminidase), can be used to increase O-GlcNAc

27 Endo-beta-N-acetylglucosaminidase completely removed the radiolabel

28 Alpha-N-acetylglucosaminidase deficiency (mucopolysaccharidosis

29 The phenotype of the alpha-N-acetylglucosaminidase-deficient mice is sufficiently sim

30 N-Acetylglucosamine-1-phosphodiester alpha-N-Acetylglucosaminidase (EC 3.1.4.45; phosphodiester alpha

31 us suggestion that the broad-spectrum beta-N-acetylglucosaminidase encoded by the SfGlcNAcase-3/SfHex

32 297 by the streptococcal enzyme endo-beta-N-acetylglucosaminidase (EndoS) induced a dominant suppres

33 ical synthesis was combined with endo-beta-N-acetylglucosaminidase (ENGase) catalysis to allow the co

34 modifications are generated when endo-beta-N-acetylglucosaminidase (ENGase) cleaves N-linked glycans.

35 The endo-beta-N-acetylglucosaminidases (ENGases) are an enzyme class (EC

36 III B) is caused by a deficiency of alpha-N-acetylglucosaminidase enzyme (Naglu), leading to accumul

37 cted protein sequence is unique among beta-N-acetylglucosaminidases excepting Cht60, recently cloned

38 lases comprise an endoenzyme, and the beta-N-acetylglucosaminidase, ExoI, reported here.

39 Endo-beta-N-acetylglucosaminidase F(3) cleaves the beta(1-4) link be

40 r Flavobacterium meningosepticum endo-beta-N-acetylglucosaminidases F2 and F3.

41 ng peptide : N-glycosidase F and endo-beta-N-acetylglucosaminidase F3 resulted in the formation of cr

42 can be either trimmed by a processing beta-N-acetylglucosaminidase (FDL) to produce paucimannosidic N

43 The endo-beta-N-acetylglucosaminidase from Arthrobacter protophormiae (E

44 ansglycosylation activity of the endo-beta-N-acetylglucosaminidase from Arthrobacter protophormiae (E

45 on a representative member, the Nag3 beta-N-acetylglucosaminidase from Cellulomonas fimi, we now sho

46 Endo-beta-N-acetylglucosaminidase from Streptococcus pneumoniae (End

47 ansglycosylation activity of the endo-beta-N-acetylglucosaminidases from Arthrobacter protophormiae (

48 companying papers describe two unique beta-N-acetylglucosaminidases from Vibrio furnissii.

49 t allows sequential isolation of endo-beta-N-acetylglucosaminidase H (EC 3.2.1.96)-released high-mann

50 immunoprecipitates digested with endo-beta-N-acetylglucosaminidase H (Endo H), indicate that ZP3 is s

51 paragine amidase (PNGase F)- and endo-beta-N-acetylglucosaminidase H (Endo H)-released oligosaccharid

52 Using endo-beta-N-acetylglucosaminidase H and peptide:N-glycosidase F sens

53 rylated, but it was sensitive to endo-beta-N-acetylglucosaminidase H and to glycopeptidase A.

54 ion to functional heterogeneity, endo-beta-N-acetylglucosaminidase H digestion and glycomic profiling

55 etry, brefeldin A treatment, and endo-beta-N-acetylglucosaminidase H digestion suggested that glycosy

56 ked oligosaccharides released by endo-beta-N-acetylglucosaminidase H from Schizosaccharomyces pombe g

57 action of Streptomyces plicatus endo-beta-N-acetylglucosaminidase H on RNase B.

58 Both proteins remained endo-beta-N-acetylglucosaminidase H sensitive, indicating that the C

59 secreted enzyme were cleaved by endo-beta-N-acetylglucosaminidase H, with phosphate present on the s

60 an bind GlcNAc through the N-terminal beta-N-acetylglucosaminidase homology domain.

61 acetylglucosaminyltransferase and O-linked N-acetylglucosaminidase in an antagonistic manner.

62 re potent and selective inhibitors of beta-N-acetylglucosaminidases in the submicromolar range.

63 absence of this specific, processing beta-N-acetylglucosaminidase is a key factor distinguishing the

64 age disorder caused by deficiency of alpha-N-acetylglucosaminidase; it is characterized by profound m

65 Identified herein as an N-acetylglucosaminidase, LytB is involved also in coloniza

66 this route for prenatal delivery of alpha-N-acetylglucosaminidase (Naglu) enzyme into the enzyme-def

67 erotype 2/5 (rAAV2/5) encoding human alpha-N-acetylglucosaminidase (NAGLU) plus immunosuppressive the

68 use is mutation in the gene encoding alpha-N-acetylglucosaminidase (NAGLU), deficiency of NAGLU, and

69 caused by a deficiency of lysosomal alpha-N-acetylglucosaminidase (NAGLU).

70 The N-acetylglucosaminidase NagZ of Pseudomonas aeruginosa cat

71 ied transgenic mice that over express beta-N-acetylglucosaminidase (O-GlcNAcase), an enzyme that cata

72 rase (OGT), which adds the sugar, and beta-N-acetylglucosaminidase (O-GlcNAcase), which hydrolyzes it

73 f N-acetylglucosamine is regulated by beta-N-acetylglucosaminidase (O-GlcNAcase), which was previousl

74 ther characterize the recently cloned beta-N-acetylglucosaminidase, O-GlcNAcase.

75 gene encodes the specific, processing beta-N-acetylglucosaminidase of Drosophila melanogaster.

76 The beta-N-acetylglucosaminidase of Escherichia coli was found to h

77 -fdl encodes the specific, processing beta-N-acetylglucosaminidase of S. frugiperda and validate our

78 ucosaminyltransferase) and removal (O-beta-N-acetylglucosaminidase) of the monosaccharide.

79 sive disease caused by deficiency of alpha-N-acetylglucosaminidase, one of the enzymes required for t

80 gars on these moieties with mannosidase or N-acetylglucosaminidase, or the cleavage of the protein th

81 In the absence of the sleL-encoded N-acetylglucosaminidase, other cortex-lytic enzymes break

82 N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase (phosphodiester alpha-GlcNAcase) w

83 as a natural substrate for beta-(1 --> 4) N-acetylglucosaminidase producing a species possessing a s

84 ct inhibition of the peptide O-GlcNAc-beta-N-acetylglucosaminidase since neither the O-GlcNAc transfe

85 ase (NanA), beta-galactosidase (BgaA), and N-acetylglucosaminidase (StrH), have been previously demon

86 ear the amino or the carboxyl end of alpha-N-acetylglucosaminidase, suggesting a role for these regio

87 concluded that dspB encodes a soluble beta-N-acetylglucosaminidase that causes detachment and dispers

88 at this gene encodes a broad-spectrum beta-N-acetylglucosaminidase that functions in glycan and chiti

89 SleL is an N-acetylglucosaminidase that plays the major role in hydro

90 olase family GH85 is a family of endo-beta-N-acetylglucosaminidases that is responsible for the hydro

91 stent with this observation, inhibition of N-acetylglucosaminidase, the enzyme involved in the remova

92 N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase ("uncovering enzyme" (UCE)).

93 GlcNAc-1-phosphodiester-N-acetylglucosaminidase ("uncovering enzyme" (UCE); EC 3.1

94 sferase) and GlcNAc-1-phosphodiester alpha-N-acetylglucosaminidase ("uncovering enzyme" or UCE).

95 estion by protein phosphatase 1 and beta-d-N-acetylglucosaminidase was more pronounced in STZ-diabeti

96 An exception to this is beta-N-acetylglucosaminidase, where 15% of the activity binds t

97 eatment of the soluble complexes with beta-N-acetylglucosaminidase, which catalyzes hydrolysis of the

98 e structure is produced by an unusual beta-N-acetylglucosaminidase, which removes the terminal N-acet