ライフサイエンスコーパス: acetyltransferase

1 e production of acetylcholine (i.e., choline acetyltransferase).

2 the first report of a virally encoded sugar acetyltransferase.

3 in of H3K36me3, and the KAT5 (TIP60) histone acetyltransferase.

4 which is generated at DSBs by the Tip60/KAT5 acetyltransferase.

5 y attached leader peptides and a GNAT-type N-acetyltransferase.

6 alk mechanism, which is mediated by the Gcn5 acetyltransferase.

7 e yvoF gene product was identified to be the acetyltransferase.

8 lpha acetylation through activating the GCN5 acetyltransferase.

9 olyamine bound in an allosteric site of an N-acetyltransferase.

10 pendently of Smc3p's regulation by the Eco1p acetyltransferase.

11 interacting with and activating three lysine acetyltransferases.

12 anding the structure/function of non-histone acetyltransferases.

13 used to identify substrate sites of histone acetyltransferases.

14 an important feedback mechanism to regulate acetyltransferases.

15 nit by members of the Eco1 family of cohesin acetyltransferases.

16 into the virulence activity of YopJ class of acetyltransferases.

17 Mitochondrial acetyl-CoA acetyltransferase 1 (ACAT1) regulates pyruvate dehydroge

18 tetrameric form of mitochondrial acetyl-coA acetyltransferase 1 (ACAT1).

19 ession of HBP enzyme glucosamine-phosphate N-acetyltransferase 1 (GNPNAT1) is found to be significant

20 Histone acetyltransferase 1 (Hat1) catalyzes the acetylation of

21 Histone acetyltransferase 1 (HAT1), which catalyzes H4K5ac and H

22 We also uncovered the histone acetyltransferase 1 (HAT1)-RBBP7 lysine acetylase comple

23 dentified the SAT1 (spermidine/spermine N(1)-acetyltransferase 1) gene as a transcription target of p

24 N-alpha-acetyltransferase 10 protein (Naa10p) catalyzes N-alpha-

25 6 (TMPRSS6), transferrin receptor (TFR2), N-acetyltransferase 2 (arylamine N-acetyltransferase) (NAT

26 eotide polymorphism in the human arylamine N-acetyltransferase 2 (Nat2) gene has recently been identi

27 N-acetyltransferase 2 (NAT2) is the only known locus influ

28 leus in human cell lines and binds to lysine acetyltransferase 2A (KAT2A, also known as GCN5) in the

29 The lysine acetyltransferase 6 (KAT6) histone acetyltransferase (HA

30 The bacterial enzyme aminoglycoside acetyltransferase(6')-Ie/aminoglycoside phosphotransfera

31 Nalpha-Acetyltransferase 60 (Naa60 or NatF) was recently identi

32 K (lysine) acetyltransferase 8 (KAT8), an important component of th

33 K(lysine) acetyltransferase 8 (KAT8, also known as MOF) mediates t

34 encodes the neuronal NAA-synthetic enzyme N-acetyltransferase-8-like.

35 The OAP gene cluster consists of a PG O-acetyltransferase A (patA) for translocation of acetate

36 After overexpression of arylalkylamine N-acetyltransferase (AANAT; the enzyme regulating melatoni

37 rast to previous dCas9-based activators, the acetyltransferase activates genes from enhancer regions

38 with deSUMOylase, deubiquitinase, or, even, acetyltransferase activities.

39 t acts as a pioneer factor, recruiting H3K27 acetyltransferase activity and opening the locus for tra

40 Pharmacological inhibition of P300 acetyltransferase activity by a specific inhibitor impro

41 Reduction of precuneus choline acetyltransferase activity co-occurs with greater beta-a

42 4 fusions resulted in loss of histone lysine acetyltransferase activity in a dominant-negative fashio

43 This binding activates N-acetyltransferase activity in the C-terminal GCN5-relate

44 n mutant illustrated the requirement for MOF acetyltransferase activity in the clonogenic capacity of

45 ESK1 has xylan O-acetyltransferase activity in vitro.

46 We suggest that P300 acetyltransferase activity may be a promising therapeuti

47 of mechanosensitivity is dependent upon the acetyltransferase activity of Atat1, which when absent l

48 esidues, S349 and S351, are required for the acetyltransferase activity of HopZ1a in vitro and are in

49 tic co-factor and significantly enhances the acetyltransferase activity of several YopJ family effect

50 ion of RUVBL1 is critically required for the acetyltransferase activity of TIP60, promoting histone H

51 RSV infection activates BRD4 acetyltransferase activity on histone H3 Lys (K) 122, de

52 We also find that impairing KAT2A/2B-acetyltransferase activity results in diminished phospho

53 elucidated the regulatory mechanisms of p300 acetyltransferase activity, but it is not known whether

54 additional amino acid residues important for acetyltransferase activity, we isolated and characterize

55 ve small molecule inhibitors of their lysine acetyltransferase activity, we validate CBP/p300 as ther

56 The Mtb Rv2170 protein shows lysine acetyltransferase activity, which is capable of post-tra

57 spho-Ser 2 RNA Pol II formation, and histone acetyltransferase activity.

58 unction is mediated via its targeted histone acetyltransferase activity.

59 Ralstonia solanacerum, also abolished their acetyltransferase activity.

60 polymerase II, and by its intrinsic histone acetyltransferase activity.

61 re transcriptional coactivators with histone acetyltransferase activity.

62 increased the protein level of HIPK2 via its acetyltransferase activity.

63 Agmatine N-acetyltransferase (AgmNAT) catalyzes the formation of N-

64 Although it is known that the alpha-tubulin acetyltransferase (alphaTAT1) is the primary enzyme resp

65 x structure with those of 14-3-3:serotonin N-acetyltransferase and 14-3-3:heat shock protein beta-6 c

66 SRP2BP, a coactivator for CRP2, is a histone acetyltransferase and a driver of smooth muscle gene exp

67 e identified KAT9 and HDAC3 as the potential acetyltransferase and deacetylase, respectively, for PGK

68 inding activity is also promoted by the Eco1 acetyltransferase and inhibited by Wpl1.

69 ce staining using antibodies against choline-acetyltransferase and neurofilament was performed to dif

70 w small molecule induced recruitment of P300 acetyltransferase and the acetylation of H3K27 at precis

71 C/EBPepsilon acetylation levels by the p300 acetyltransferase and the sirtuin 1 deacetylase controls

72 ons, suggesting that BRPF1 targets these two acetyltransferases and additional partners in humans.

73 ty to depletion and/or inhibition of histone acetyltransferases and CDK9 and less sensitivity to hist

74 Histone acetyltransferases and histone deacetylases (HDACs) are

75 controlled by the opposing action of histone acetyltransferases and histone deacetylases (HDACs).

76 identify CBP, p300, and pCAF as RhoGDIalpha-acetyltransferases and Sirt2 and HDAC6 as specific deace

77 ct coactivator complexes, SAGA (Spt Ada Gcn5 acetyltransferase) and ATAC (Ada Two A-containing).

78 f microtubule stabilizers, including tubulin acetyltransferases; and (3) genetic epistasis suggests t

79 In both yeasts, these acetyltransferases are essential for cell viability.

80 d mass spectrometry, we identified the EP300 acetyltransferase as uniquely associated with BRD4 throu

81 F1 encodes a protein modifier of two histone acetyltransferases associated with ID: KAT6A (also known

82 Thus, KAT7-containing acetyltransferases associating with the Mis18 complex pr

83 rt therapies targeting endoplasmic reticulum acetyltransferases, ATase1 and ATase2, for a subset of c

84 onstrate that mice lacking the alpha-tubulin acetyltransferase Atat1 in sensory neurons display profo

85 nd identifying substrates for the N-terminal acetyltransferase B (NatB) complex.

86 Peptidoglycan O-acetyltransferase B (PatB) catalyzes the O-acetylation o

87 cation of acetate into the periplasm, a PG O-acetyltransferase B (patB) for O-acetylation, and an O-a

88 eads to a specific activation of the histone acetyltransferase Brd2, which results in histone H3K27 a

89 first time, the structural regulation of an acetyltransferase by autoacetylation in a prokaryotic or

90 on of NOS with tyrosine hydroxylase, choline acetyltransferase, calbindin, calretinin, and serotonin,

91 own that pathogen effector proteins encoding acetyltransferases can directly acetylate host proteins

92 l (Cm) when resistant bacteria expressing Cm acetyltransferase (CAT) are present.

93 t purpose, we decided to use chloramphenicol acetyltransferase (CAT), as chloroplasts are particularl

94 ions but, rather, are required to orient its acetyltransferase catalytic site to the methylated histo

95 d that the L142 N-terminal domain is a sugar acetyltransferase, catalyzing the transfer of an acetyl

96 tically, DEX-bound GR recruits histone H3K27 acetyltransferase CBP to promote activation of C/EBPbeta

97 cetylation likely catalyzed by the conserved acetyltransferase CBP.

98 ation associated with recruitment of histone acetyltransferase CBP.

99 me1/2 methyltransferases MLL3/MLL4 and H3K27 acetyltransferases CBP/p300 are major enhancer epigenomi

100 ansferases MLL3/MLL4 (KMT2C/KMT2D) and H3K27 acetyltransferases CBP/p300 to recruit Brd4 to enhancers

101 immunohistochemical visualization of choline acetyltransferase (ChAT) and the low-affinity neurotroph

102 the critical neurotransmitter enzyme choline acetyltransferase (ChAT) by in vitro motor neurons, like

103 ally ubiquitinated proteins, reduced choline acetyltransferase (ChAT) enzyme expression, fragmented m

104 ing retrograde tracing combined with choline acetyltransferase (ChAT) immunohistochemistry in rats.

105 ales at 1 and 4 months of age, using choline acetyltransferase (ChAT) immunolabeling to identify chol

106 and interneurons immunoreactive for choline acetyltransferase (ChAT) in regions of the executive and

107 istochemistry 14 d after MI revealed choline acetyltransferase (ChAT) in stellate sympathetic neurons

108 iny neurons (MSNs) and D2-expressing choline acetyltransferase (ChAT) interneurons express Slc6a15, w

109 Selective deletion of p11 in cholinergic acetyltransferase (ChAT) neurons reduces tacrine-induced

110 lutamic acid decarboxylase (GAD) and choline acetyltransferase (ChAT) revealed that all CG neurons ar

111 ecause of their immunoreactivity for choline acetyltransferase (ChAT), contradictory findings, includ

112 ported to potentiate the activity of choline acetyltransferase (ChAT), the enzyme that produces the n

113 at CD4(+) T lymphocytes that express choline acetyltransferase (ChAT), which catalyzes the synthesis

114 able to glaucomatous damage, whereas choline acetyltransferase (ChAT)-positive and glycinergic AC sub

115 sicular acetylcholine transporter or choline acetyltransferase (ChAT).

116 ate decarboxylases (gad1, gad2), and choline acetyltransferase (chat).

117 essed this process by inhibiting the histone acetyltransferase coactivator p300, preventing the induc

118 The NuA4 acetyltransferase complex contains two of these reader m

119 The evolutionarily conserved histone acetyltransferase complex Elongator was identified as a

120 NuA4 is the only essential lysine acetyltransferase complex in Saccharomyces cerevisiae, w

121 The NuA4/TIP60 acetyltransferase complex is a key regulator of genome e

122 ractors were components of the TIP60 histone acetyltransferase complex.

123 ay also function independently of the lysine acetyltransferase complex.

124 hologous to subunits of a mammalian MOZ/MORF acetyltransferase complex.

125 protein required for the assembly of histone acetyltransferase complexes, where the gene of MOZ (mono

126 e describe a programmable, CRISPR-Cas9-based acetyltransferase consisting of the nuclease-null dCas9

127 We find that the ESCO1 acetyltransferase core is structurally homologous to the

128 ing (CREB) interaction domain of the histone acetyltransferase CREB-binding protein (CBP).

129 We also noted that the acetyltransferases CREB-binding protein and p300 both ca

130 N-alpha-acetyltransferase D (NatD) mediates N-alpha-terminal ace

131 Alteration of residues unique to the acetyltransferases did not alter the unique acyl donor s

132 n deregulated expression of dihydrolipoamide acetyltransferase (Dlat), a gene encoding the E2 subunit

133 was dependent on bacterial dihydrolipoamide acetyltransferase (DlaT), a major protein expressed on t

134 olved in histone acetylation via its histone acetyltransferase domain (HAT) and, as a result, activat

135 otransferase(2'')-Ia possesses an N-terminal acetyltransferase domain and a C-terminal phosphotransfe

136 Rescue experiments with a MOF histone acetyltransferase domain mutant illustrated the requirem

137 Missense mutations within the acetyltransferase domain of these proteins correlate wit

138 the role of missense mutations in the lysine acetyltransferase domain that are more frequently observ

139 ly of bacterial effectors depends on a novel acetyltransferase domain to acetylate signalling protein

140 se activity in the C-terminal GCN5-related N-acetyltransferase domain, which is required for GlcNAc-i

141 rrent inhibitors of the p300 and CBP histone acetyltransferase domains, including natural products, b

142 The acetyltransferase, E1a-binding protein (p300), is propos

143 Euonymus alatus diacylglycerol acetyltransferase (EaDAcT) catalyzes the transfer of an

144 DDK also phosphorylates the cohesin acetyltransferase Eco1 [8].

145 We show that cohesin acetyltransferase Eco1 targets lysine 20 at the sliding

146 -terminal lysines of the Smc3 subunit by the acetyltransferases Eco1 in Saccharomyces cerevisiae and

147 ate inhibitors of Mycobacterium tuberculosis acetyltransferase Eis, whose upregulation causes resista

148 Spermidine N-acetyltransferase, encoded by the gene speG, catalyzes t

149 gh-throughput screens against an amino-sugar acetyltransferase enzyme, PglD, involved in biosynthesis

150 al modification that is regulated by diverse acetyltransferase enzymes.

151 tically, far less is known about non-histone acetyltransferase enzymes.

152 c stress increased expression of the histone acetyltransferase EP300 and increased histone acetylatio

153 In turn, Hdac3 recruited histone acetyltransferase Ep300 to form an enhanceosome complex

154 es and concurrent recruitment of the histone acetyltransferase EP300 to MEF2 target gene regulatory e

155 gh induction of nuclear translocation of the acetyltransferase EP300, which increases histone H3K27 a

156 arrangements of the ZNF384 gene with histone acetyltransferases EP300 and CREBBP ZNF384-rearranged AL

157 rgic forebrain neurons, we activated choline acetyltransferase expressing neurons using channelrhodop

158 etyl-CREB-binding protein (CBP/p300) histone acetyltransferase expression in a time and dose-dependen

159 n the other hand, PAF increased p300 histone acetyltransferase expression, and the acetylation of his

160 T2A) is a member of the GNAT (Gcn5-related N-acetyltransferase) family of HATs.

161 Among them, the acetyltransferase from Euonymus fortunei possessed the h

162 rase activity, we isolated and characterized acetyltransferases from other acetyl-TAG-producing plant

163 ransgenic lines with decreased expression of acetyltransferases from the MYST family.

164 that mice lacking enzymatic activity of the acetyltransferase GCN5 ((Gcn5(hat/hat) )), which were pr

165 esidues, which specifically recruits histone acetyltransferase GCN5 for subsequent H3 acetylation.

166 Here we demonstrate a novel role of the acetyltransferase GCN5 in a previously undescribed mecha

167 We also find that the acetyltransferase Gcn5 synergizes with Spt3 to promote g

168 me remodelers INO80 or ISW1A, and the lysine acetyltransferases Gcn5 and Esa1 each contribute separat

169 presence of inactivating mutations in the O-acetyltransferase gene wciG Complementation studies in a

170 hemophilic red alga with the chloramphenicol acetyltransferase gene, rendering this organism insensit

171 hemophilic red alga with the chloramphenicol acetyltransferase gene, rendering this organism insensit

172 was recently reported, but the presence of O-acetyltransferase genes in the serotype 35C cps locus su

173 coccal serotype 33A has two membrane-bound O-acetyltransferase genes, wciG and wcjE A 33A wcjE-defici

174 Loss of the histone acetyltransferase (HAT) activity blocks oogenesis, while

175 ation; this microRNA alters HDAC and histone acetyltransferase (HAT) activity, which suggests a role

176 s two enzymatic modules, which house histone acetyltransferase (HAT) and deubiquitinase (DUB) activit

177 Chromatin remodeling through histone acetyltransferase (HAT) and histone deactylase (HDAC) en

178 Using steady-state histone acetyltransferase (HAT) assays, we show that an RNA bind

179 ain of PHF20, which recruits the MOF histone acetyltransferase (HAT) complex to ERalpha target gene p

180 nger 1) is a core subunit of the MOZ histone acetyltransferase (HAT) complex, critical for normal dev

181 he lysine acetyltransferase 6 (KAT6) histone acetyltransferase (HAT) complexes are highly conserved f

182 s an essential component of specific histone acetyltransferase (HAT) complexes.

183 phthora sojae acts as a modulator of histone acetyltransferase (HAT) in plants.

184 The histone acetyltransferase (HAT) inhibitor garcinol or vehicle wa

185 Several histone acetyltransferase (HAT) inhibitors with these liabilitie

186 this manner, we discovered the H4K16 histone acetyltransferase (HAT) MOF to be important for leukemia

187 cetylation of proteins, catalysed by histone acetyltransferases (HATs) and histone deacetylases (HDAC

188 Histone acetyltransferases (HATs) and histone deacetylases (HDAC

189 KAT6 histone acetyltransferases (HATs) are highly conserved in eukary

190 Although histone acetyltransferases (HATs) have been well characterized b

191 kDa protein) are two closely related histone acetyltransferases (HATs) that play a key role in the re

192 We assess the ability of seven histone acetyltransferases (HATs) to catalyze acylations on hist

193 nucleosome remodeling complexes, and histone acetyltransferases have been implicated in nucleosome di

194 Lysine acetyltransferases have been shown to regulate various s

195 MYST histone acetyltransferases have crucial functions in transcripti

196 Histone acetyltransferase HBO1 might acetylate this residue.

197 ctivity, and it diminished the total histone acetyltransferase/HDAC activity ratio in mouse lungs exp

198 DAC activity but increased the total histone acetyltransferase/HDAC activity ratio in mouse lungs.

199 The Eco1 acetyltransferase, helped by factors including Ctf4 and

200 ound that upregulated translation of choline acetyltransferase in the CPEB2 KO dorsal motor nucleus o

201 genes, including fucosyl-, galactosyl-, and acetyltransferases, in the corresponding Arabidopsis mut

202 m (ER) stress and protein levels of P300, an acetyltransferase involved in glucose production.

203 iciency of acetyl-CoA: alpha-glucosaminide N-acetyltransferase involved in the lysosomal catabolism o

204 ch encodes a plant-specific polysaccharide O-acetyltransferase involved in xylan acetylation.

205 We conclude that the CSRP2BP histone acetyltransferase is a coactivator for CRP2 that works s

206 The MYST family of histone acetyltransferases is autoacetylated at an active site l

207 , in the absence of NuA4, SAGA (Spt-Ada-Gcn5-acetyltransferase) is involved in targeting the TAF-inde

208 that ESKIMO1/XOAT1/TBL29, a xylan-specific O-acetyltransferase, is necessary for generation of the ev

209 lexes containing opposing lysine and histone acetyltransferase (KAT and HAT) and deacetylase (KDAC an

210 teins, and it also harbors lysine N(epsilon)-acetyltransferase (KAT) activity to catalyze the acetyla

211 , we explore an emerging concept that lysine acetyltransferase (KAT) enzymes drive cellular plasticit

212 NuA4 histone lysine (K) acetyltransferase (KAT) promotes transcriptional initiat

213 nically targeted, the role of histone lysine acetyltransferases (KAT) in malignancy is less well char

214 erize cellular functions of the human lysine acetyltransferases KAT2A (GCN5) and KAT2B (PCAF), we det

215 osome-binding domains and activates 3 lysine acetyltransferases (KAT6A, KAT6B, and KAT7), suggesting

216 complex is to transiently recruit the lysine acetyltransferase KAT7 to centromeres to facilitate the

217 on between CENP-A assembly factor M18BP1 and acetyltransferase KAT7/HBO1/MYST2.

218 Lysine acetyltransferases (KATs) are key mediators of cell sign

219 Lysine deacetylases (KDACs) and acetyltransferases (KATs) maintain the acetylation equil

220 enzyme YvoF is a close relative of maltose O-acetyltransferase (MAT).

221 tructure of the highly conserved zinc finger-acetyltransferase moiety of ESCO1 with accompanying stru

222 The histone acetyltransferase MOZ (MYST3, KAT6A) is the target of re

223 uvancy with a staphylococcal peptidoglycan O-acetyltransferase mutant reduces IL-10, increases IL-1be

224 One such enzyme is homologous to arylamine N-acetyltransferase (NAT) and has been identified in Fusar

225 y identified as an unconventional N-terminal acetyltransferase (NAT) because it localizes to organell

226 es and is mediated by a family of N-terminal acetyltransferases (NAT).

227 r (TFR2), N-acetyltransferase 2 (arylamine N-acetyltransferase) (NAT2), ABO blood group (ABO), and GR

228 The N-terminal acetyltransferase NatA is a heterodimeric complex consis

229 t of apocynin on the activity of arylamine N-acetyltransferases (NATs) in excised liver samples was e

230 al acetylation (NTA) catalysed by N-terminal acetyltransferases (Nats) is among the most common prote

231 (Nt-acetylation), carried out by N-terminal acetyltransferases (NATs), is a conserved and primary mo

232 yotic cell carried out by six amino-terminal acetyltransferases (NATs).

233 HR), or channelrhodopsin-2 (ChR2) in Choline acetyltransferase neurons (ChAT(+)) or Arch in LIM-homeo

234 Choline acetyltransferase neurons in the vertical diagonal band

235 n N-deacetylase PgdA and the peptidoglycan O-acetyltransferase OatA.

236 ins important for the recruitment of histone acetyltransferases of the MYST family to chromatin.

237 ins important for the recruitment of histone acetyltransferases of the MYST family to chromatin.

238 echanistically, Wnt3a does not alter histone acetyltransferase or deacetylase activities but, rather,

239 in protein activation, including the histone acetyltransferase p300 acetylated in its activation loop

240 ATA6 or transcriptional co-activator/histone acetyltransferase p300 decreased AQP5 expression, while

241 The histone acetyltransferase p300 is normally associated with the A

242 ators Sp1 and HIF-1 colocalized with histone acetyltransferase p300 on ncx1-Br with a consequent hype

243 Furthermore, we found that histone acetyltransferase p300 supported the recruitment of BRD4

244 tin association, and associates with histone acetyltransferase p300 to enhance Smad transcriptional a

245 DH:NAD(+) ratio regulate CtBP binding to the acetyltransferase p300, and regulate binding of p300 and

246 upon HDAC inhibition, partly by the histone acetyltransferase p300, and that both NF-kappaB and p300

247 L4 is required for enhancer-binding of H3K27 acetyltransferase p300, enhancer activation, and inducti

248 Yap strongly induces the acetyltransferase p300-mediated acetylation of the E3 li

249 4 methyltransferase) complex and the histone acetyltransferase p300.

250 ein fused to the catalytic core of the human acetyltransferase p300.

251 ivity was necessary for c-Myc binding to the acetyltransferase p300.

252 l-CoA and isobutyryl-CoA interacted with the acetyltransferase P300/CBP-associated factor (PCAF) in l

253 we identify a novel activity of the histone acetyltransferase p300/CREB-binding protein (CBP) in reg

254 between the DUX4 C-terminus and the histone acetyltransferases p300/CBP.

255 olecular level, hG9a interacted with histone acetyltransferase, p300/CBP, resulting in increased hist

256 The histone acetyltransferase paralogues p300 and CREB-binding prote

257 laphos resistance (BAR) and phosphinothricin acetyltransferase (PAT) genes, which convey resistance t

258 s modification, reversibly controlled by the acetyltransferase Pka, and the deacetylase CobB, affects

259 f cells was 197 +/- 23, and 92% were choline acetyltransferase positive, implying a cholinergic role.

260 Choline acetyltransferase-positive neurons were Fluorogold-negat

261 the transamination pathway activate the GCN5 acetyltransferase promoting acetylation of the transcrip

262 coli, PatZ (formerly YfiQ) is the only known acetyltransferase protein and is responsible for acetyl-

263 alkyl hydroperoxide reductase and acetyl-CoA acetyltransferase, recognizing TPT were crucial to TPT d

264 on during lung cancer progression.NatD is an acetyltransferase responsible for N-alpha-terminal acety

265 repairable DSBs also depends on the histone acetyltransferase Rtt109 and the cullin subunit Rtt101,

266 Indeed the mycobacterial Pat (protein lysine acetyltransferase), Rv0998, specifically acetylates MbtA

267 ide screen and demonstrated that the histone acetyltransferase SAGA and the activity of histone deace

268 The Spt-Ada-Gcn5-acetyltransferase (SAGA) chromatin-modifying complex is

269 Deubiquitination of H2B by the Spt-Ada-Gcn5 acetyltransferase (SAGA) coactivator complex is regulate

270 H2B is deubiquitinated by the Spt-Ada-Gcn5 acetyltransferase (SAGA) coactivator, which contains a f

271 The Spt-Ada-Gcn5 acetyltransferase (SAGA) H2B deubiquitinase module compe

272 snRNP) are also subunits of the Spt-Ada-Gcn5 acetyltransferase (SAGA) transcriptional coactivator com

273 m), an activator of spermidine/spermine N(1)-acetyltransferase (SAT1).

274 Depletion of the tubulin acetyltransferase TAT1 led to a significant increase in

275 campestris The P. syringae T3SE HopZ1a is an acetyltransferase that acetylates the pseudokinase AtZED

276 her, this study identifies the first histone acetyltransferase that activates ERalpha expression whic

277 a, suggesting MYST3 functioning as a histone acetyltransferase that activates ERalpha promoter.

278 e we reveal that one such toxin, TacT, is an acetyltransferase that blocks the primary amine group of

279 reticulum lumen, and ATase1 and ATase2, two acetyltransferases that acetylate endoplasmic reticulum

280 icant homology with some characterized sugar acetyltransferases that modify the C-4 amino group in th

281 When applied to N-acetyltransferases, this reveals sequence and structural

282 the methyltransferase MMSET (WHSC1) and the acetyltransferase Tip60 (KAT5) to the DSB, where local l

283 compaction pathway is defective, the histone acetyltransferase Tip60 is recruited to pericentric hete

284 ster regulator Foxp3 mediated by the histone acetyltransferase Tip60, which targeted Foxp3 for protea

285 cluding histone demethylase LSD1 and histone acetyltransferase Tip60.

286 how oncogenic events signal through distinct acetyltransferases to regulate cancer metabolism and sug

287 Th9 cells by binding and recruiting histone acetyltransferases to the Il9 locus at sites distinct fr

288 GmvT is an acetyltransferase toxin that inhibits protein translatio

289 these 2 CpGs impaired binding of the histone acetyltransferase/transcriptional coactivator p300 to th

290 tubulin, human neuronal protein C/D, choline acetyltransferase, tyrosine hydroxylase, neuronal nitric

291 Many histone acetyltransferases undergo autoacetylation, either throu

292 Remarkably, E. coli serine O-acetyltransferase uses a similar Gly-Asp-Gly-Ile motif t

293 Chromatin-monitoring KAT5 (Tip60) acetyltransferase was responsible for acetylation and ac

294 We demonstrated that the O-acetyltransferase WciG was functional in serotype 35C bu

295 e discovery of five cytochrome P450s and two acetyltransferases which catalyze a cascade of reactions

296 ely target the catalytic activity of histone acetyltransferases, which may provide effective treatmen

297 ssion and identify KAT8 as the first histone acetyltransferase with an essential function in oogenesi

298 stained association of NFAT and p300 histone acetyltransferase with the IP-10 gene required p38 and c

299 Gcn5, the acetyltransferase within the SAGA complex, was found to

300 eacetylate acetylated MDH, while the E. coli acetyltransferase YfiQ cannot acetylate MDH efficiently.