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1 haled CO2 to induce an acidosis and activate acid sensing ion channels.
2 t, is essential for proton activation of the acid-sensing ion channels.
3 at of previously described native and cloned acid-sensing ion channels.
4 er subdomains in the extracellular domain of acid-sensing ion channels.
5 mediated by the capsaicin receptor TRPV1 and acid-sensing ion channels.
6 he extracellular thumb domain in the chicken acid sensing ion channel 1 structure.
7                                              Acid-sensing ion channel 1 (ASIC1) is a H(+)-gated chann
8                                              Acid-sensing ion channel 1 (ASIC1) is homologous to ENaC
9 dy, we show that breast cancer cells express acid-sensing ion channel 1 (ASIC1), a proton-gated catio
10            The resolved crystal structure of acid-sensing ion channel 1 (ASIC1), a structurally relat
11                                    Targeting acid-sensing ion channel 1 (encoded by the ASIC1 gene),
12 es to describe in detail the distribution of acid-sensing ion channel 1 and its relationship with neu
13 lammatory lesions is unknown and, crucially, acid-sensing ion channel 1 expression has not been deter
14 ver, the extent and cellular distribution of acid-sensing ion channel 1 expression in neurons and gli
15 ther these findings suggest that blockade of acid-sensing ion channel 1 has the potential to provide
16 ctivation in in vivo migraine models, via an acid-sensing ion channel 1 mechanism.
17                            The expression of acid-sensing ion channel 1 was associated with axonal da
18                                We found that acid-sensing ion channel 1 was upregulated in axons and
19                We previously showed that the acid-sensing ion channel 1 which, when activated under t
20                           Moreover, blocking acid-sensing ion channel 1 with amiloride protected both
21            Based on structural homology with acid-sensing ion channel 1, gammaAsp(516) was predicted
22                                              Acid-sensing ion channel-1 (ASIC-1) is a proton-gated io
23                                          The acid-sensing ion channel-1 (ASIC1) contributes to synapt
24       The neuronally expressed, proton-gated acid-sensing ion channel-1 (ASIC1) is permeable to Na+ a
25           SGK1.1 decreases expression of the acid-sensing ion channel-1 (ASIC1); thereby, SGK1.1 may
26 k examines the interaction of amiloride with acid-sensing ion channel-1, a protein whose structure is
27                                              Acid sensing ion channels 1a (ASIC1a) are of crucial imp
28                                              Acid-sensing ion channel 1a (ASIC1a) has been shown to p
29                             Protons activate acid-sensing ion channel 1a (ASIC1a) in the central nerv
30                                              Acid-sensing ion channel 1A (ASIC1A) is abundant in the
31                                          The acid-sensing ion channel 1a (ASIC1a) is abundantly expre
32                                      Because acid-sensing ion channel 1a (ASIC1a) is exquisitely sens
33                                  In CA1, the acid-sensing ion channel 1a (ASIC1a) is known to facilit
34                                              Acid-sensing ion channel 1a (ASIC1a) is the primary acid
35                                          The acid-sensing ion channel 1a (ASIC1a) is widely expressed
36                                              Acid-sensing ion channel 1a (ASIC1a) promotes neuronal d
37 ces and biolistic transfection, we found the acid-sensing ion channel 1a (ASIC1a), localized in dendr
38                                          The acid-sensing ion channel 1a (ASIC1a), which is expressed
39 e methods to prepare pure samples of chicken acid-sensing ion channel 1a (cASIC1) and Caenorhabditis
40  are homologous to the Cl(-) binding site in acid-sensing ion channel 1a and tested the effect of Cl(
41 imaging that the Sig1R binds to the trimeric acid-sensing ion channel 1A with 3-fold symmetry.
42 of Held synapse express functional homomeric Acid-sensing ion channel-1a (ASIC-1as) that can be activ
43                                              Acid-sensing ion channel-1a (ASIC1a) contributes to mult
44                                              Acid-sensing ion channel-1a (ASIC1a) is a potential ther
45                                          The acid-sensing ion channel-1a (ASIC1a) is composed of 3 su
46                                              Acid-sensing ion channel-1a (ASIC1a) is localized in bra
47                                              Acid-sensing ion channel-1a (ASIC1a) mediates H(+)-gated
48 these models to test the hypothesis that the acid-sensing ion channel-1a (ASIC1a) might be targeted t
49               Because the amygdala expresses acid-sensing ion channel-1a (ASIC1a), and ASIC1a is requ
50  and anxiety-related behaviors and expresses acid-sensing ion channel-1A (ASIC1A), we hypothesized th
51 the role of the vertebrate DEG-ENaC protein, acid-sensing ion channel 2 (ASIC2), in auditory transduc
52            The acid-sensitive cation channel acid-sensing ion channel-2 (ASIC2) is widely believed to
53 , GFRalpha2-expressing sensory neurons), the acid-sensing ion channel 2a, and transient receptor pote
54 d to correlate with significant increases in acid-sensing ion channels 2A and 2B and transient recept
55 ly through regulating membrane expression of acid sensing ion channel 3.
56         Through its location on nociceptors, acid-sensing ion channel 3 (ASIC-3) is activated by decr
57 t receptor potential vanilloid 1 (TRPV1) and acid-sensing ion channel 3 (ASIC3) are peripheral mechan
58                   In rodent sensory neurons, acid-sensing ion channel 3 (ASIC3) has recently emerged
59                                              Acid-sensing ion channel 3 (ASIC3) is highly expressed o
60                                              Acid-sensing ion channel 3 (ASIC3) is involved in acid n
61 ouse model by altering the expression of the acid-sensing ion channel 3 (ASIC3) which we had identifi
62                                              Acid-sensing ion channel 3 (ASIC3), a proton-gated ion c
63                            Here we show that acid-sensing ion channel 3 (ASIC3), but no other known a
64  and IV muscle afferents via upregulation of acid-sensing ion channel 3 (ASIC3), leading not only to
65 t receptor potential vanilloid 1 (TRPV1) and acid-sensing ion channel 3 (ASIC3), on development of be
66  APETx2 is a potent and selective blocker of acid-sensing ion channel 3 (ASIC3).
67  was found exclusively in neurons expressing acid-sensing ion channel 3, where SP enhances M-channel-
68                                          The acid-sensing ion channel-3 (ASIC3) is a degenerin/epithe
69 at a specific cation conductance composed of acid-sensing ion channels and ENaC subunits regulates mi
70                                              Acid-sensing ion channels are cation channels activated
71                                              Acid-sensing ion channels are proton-activated ion chann
72                                              Acid-sensing ion channels are proton-activated, sodium-s
73                                              Acid-sensing ion channels are proton-gated Na(+) channel
74                                       ASICs (acid-sensing ion channels) are proton-gated channels tha
75 oral artery is attenuated by blockade of the acid sensing ion channel (ASIC) 3.
76                We found that eliminating the acid sensing ion channel (ASIC) abolished H(+)-gated cur
77                                              Acid sensing ion channel (ASIC)2 belongs to the amilorid
78 ation, and to investigate the involvement of acid-sensing ion channel (ASIC) -3 in the response.
79                               Interestingly, acid-sensing ion channel (ASIC) 1, 2a, 2b, and 3 mRNAs w
80                                              Acid-sensing ion channel (ASIC) 1a and ASIC2a are acid-s
81                                              Acid-sensing ion channel (ASIC) 1a subunit is expressed
82 release and a low extracellular pH, leads to acid-sensing ion channel (ASIC) activation and reflexive
83 nt in glomus cells that was inhibited by the acid-sensing ion channel (ASIC) blocker amiloride, absen
84                               Other types of acid-sensing ion channel (ASIC) channels were intact to
85 modulate the proton-sensitive members of the acid-sensing ion channel (ASIC) family.
86 date transducer molecules are members of the acid-sensing ion channel (ASIC) family; nerve fibre reco
87 ude the epithelial sodium channel (ENaC) and acid-sensing ion channel (ASIC) members of the DEG/ENaC
88 oresis of acid, suggesting an involvement of acid-sensing ion channel (ASIC) receptors.
89  to test the hypothesis that a member of the acid-sensing ion channel (ASIC) subfamily of the DEG/ENa
90                                              Acid-sensing ion channel (ASIC) subunits associate to fo
91 id channel composed of a mixture of ENaC and acid-sensing ion channel (ASIC) subunits.
92  ions, dramatically increases activity of an acid-sensing ion channel (ASIC) that is highly expressed
93                                              Acid-sensing ion channel (ASIC)-1a, the major ASIC subun
94 ns exhibited transient, amiloride-sensitive, acid-sensing ion-channel (ASIC) currents.
95  Hippocampal neurons express subunits of the acid-sensing ion channel (ASIC1 and ASIC2) and exhibit l
96 pha subunit and the resolved structure of an acid-sensing ion channel (ASIC1) have conserved acidic p
97                                          The acid-sensing ion channel, ASIC1, contributes to synaptic
98 osensing of acidosis in the amygdala via the acid-sensing ion channel ASIC1a.
99 ently of VR1, has characteristics similar to acid sensing ion channels (ASICs) and is found in the ai
100                                              Acid sensing ion channels (ASICs) are cation-selective m
101 Although thin fibre muscle afferents possess acid sensing ion channels (ASICs), their contribution to
102                Because acidosis can activate acid sensing ion channels (ASICs), we also studied ASIC1
103                                              Acid-sensing ion channels (ASICs) act as neurotransmitte
104                                     Neuronal acid-sensing ion channels (ASICs) act as sensors for ext
105                                          The acid-sensing ion channels (ASICs) are a family of ion ch
106                                              Acid-sensing ion channels (ASICs) are a group of trimeri
107                                              Acid-sensing ion channels (ASICs) are cation-selective p
108                                              Acid-sensing ion channels (ASICs) are expressed in skele
109                                              Acid-sensing ion channels (ASICs) are H(+)-gated members
110                                              Acid-sensing ion channels (ASICs) are highly expressed i
111                                              Acid-sensing ion channels (ASICs) are neuronal Na(+)-sel
112                                              Acid-sensing ion channels (ASICs) are neuronal non-volta
113                                              Acid-sensing ion channels (ASICs) are neuronal proton-ga
114                                              Acid-sensing ion channels (ASICs) are neuronal receptors
115                                              Acid-sensing ion channels (ASICs) are neuronal, voltage-
116                                              Acid-sensing ion channels (ASICs) are proton-activated c
117                                              Acid-sensing ion channels (ASICs) are proton-activated N
118                                          The acid-sensing ion channels (ASICs) are proton-gated catio
119                                              Acid-sensing ion channels (ASICs) are proton-gated catio
120                                              Acid-sensing ion channels (ASICs) are proton-gated catio
121                                              Acid-sensing ion channels (ASICs) are proton-gated Na(+)
122                                          The acid-sensing ion channels (ASICs) are proton-gated, volt
123                                              Acid-sensing ion channels (ASICs) are sodium channels ga
124                                              Acid-sensing ion channels (ASICs) are trimeric cation ch
125                                              Acid-sensing ion channels (ASICs) are trimeric cation-se
126                                              Acid-sensing ion channels (ASICs) are trimeric cation-se
127                                              Acid-sensing ion channels (ASICs) are voltage-independen
128                                              Acid-sensing ion channels (ASICs) are voltage-independen
129                                              Acid-sensing ion channels (ASICs) are voltage-independen
130                                              Acid-sensing ion channels (ASICs) are widely expressed p
131         Peripheral sensitization depended on acid-sensing ion channels (ASICs) because treatment of s
132                                              Acid-sensing ion channels (ASICs) constitute a family of
133 tion in response to inflammatory conditions, acid-sensing ion channels (ASICs) contribute to the path
134 ility of neuronal networks via activation of acid-sensing ion channels (ASICs) could have therapeutic
135                                              Acid-sensing ion channels (ASICs) detect extracellular p
136                                              Acid-sensing ion channels (ASICs) form both homotrimeric
137           In central and peripheral neurons, acid-sensing ion channels (ASICs) have emerged as key re
138                           The exact roles of acid-sensing ion channels (ASICs) in synaptic plasticity
139                                  The role of acid-sensing ion channels (ASICs) in the ventrolateral m
140 t receptor potential V1 (TRPV1) channels and acid-sensing ion channels (ASICs) is that their ion cond
141                                              Acid-sensing ion channels (ASICs) mediate chemosensitivi
142                                          The acid-sensing ion channels (ASICs) open in response to ex
143                                              Acid-sensing ion channels (ASICs) open when extracellula
144                                              Acid-sensing ion channels (ASICs) regulate synaptic acti
145 mba venom that specifically inhibit a set of acid-sensing ion channels (ASICs) to relieve pain.
146                                    Recently, acid-sensing ion channels (ASICs) were shown to act as n
147                                              Acid-sensing ion channels (ASICs), a novel class of liga
148 -inflammatory drug (NSAID) pharmacology with acid-sensing ion channels (ASICs), a small family of exc
149                                              Acid-sensing ion channels (ASICs), activated by a decrea
150                                              Acid-sensing ion channels (ASICs), activated by lowering
151                                              Acid-sensing ion channels (ASICs), expressed in thin mus
152 show that acidosis activates Ca2+ -permeable acid-sensing ion channels (ASICs), inducing glutamate re
153     Our previous results have shown that the acid-sensing ion channels (ASICs), members of the epithe
154          Potential receptors for protons are acid-sensing ion channels (ASICs), Na(+)- and Ca(2+)-per
155                                              Acid-sensing ion channels (ASICs), newly discovered memb
156 potent, persistent and selective agonist for acid-sensing ion channels (ASICs), showing equal or grea
157 ar approach was used to open and close human acid-sensing ion channels (ASICs), which are also trimer
158                            The activation of acid-sensing ion channels (ASICs), which are highly perm
159 n brain sodium channel family, also known as acid-sensing ion channels (ASICs).
160 teractions between extracellular protons and acid-sensing ion channels (ASICs).
161 are converted to excitatory sodium influx by acid-sensing ion channels (ASICs).
162                 Analysis of the known ASIC1 (acid-sensing ion channel) crystal structure suggested th
163 ere we present the structure of a functional acid-sensing ion channel in a desensitized state at 3 A
164 sensing ion channel (ASIC) 1a and ASIC2a are acid-sensing ion channels in central and peripheral neur
165 opagation, probably via mechanisms involving acid-sensing ion channels in the pilocarpine model of te
166                       Hyperactivation of the acid-sensing ion channels including degenerin/epithelial
167 39 had no effect on the structurally related acid-sensing ion channels, indicating specificity for EN
168 s support the possibility that modulation of acid-sensing ion channels may have therapeutic potential
169                   These results suggest that acid-sensing ion channels may integrate multiple extrace
170 n neuronal DEG/ENaC channels known as ASICs (acid-sensing ion channels) mediate sensory perception an
171  also found that down-regulation of Nach, an acid sensing ion channel, mitigates SCA3 pathogenesis in
172 ith acid by increasing the pH sensitivity of acid-sensing ion channel number 3 (ASIC3), the molecule
173                                              Acid-sensing ion channels, or ASICs, are members of the
174                                              Acid-sensing ion channels, or ASICs, are proton-gated ca
175 eract with the epithelial sodium channel and acid-sensing ion channel proteins, as well as sodium/hyd
176 ng ion channel 3 (ASIC3), but no other known acid-sensing ion channel, reproduces the functional feat
177                            Comparison of the acid-sensing ion channel structure with the ATP-gated P2
178             Studies further demonstrate that acid-sensing ion channel subtype 3 (ASIC(3)) in thin-fib
179 loride, a potent and nonselective blocker of acid-sensing ion channels, suppresses generalized seizur

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