ライフサイエンスコーパス: acquired immunity

1 atory activity in cells mediating innate and acquired immunity.

2 lymphocyte responses and bridges innate and acquired immunity.

3 ions to predominantly suppressive effects on acquired immunity.

4 endent manner and has pleiotropic effects on acquired immunity.

5 lls and complement participate in innate and acquired immunity.

6 licated in host responses in both innate and acquired immunity.

7 in host innate immunity and as regulators of acquired immunity.

8 ple signaling pathways regulating innate and acquired immunity.

9 l pathogens in advance of the development of acquired immunity.

10 oadly reduces innate inflammation as well as acquired immunity.

11 ells, which are important in both innate and acquired immunity.

12 of the early events leading to induction of acquired immunity.

13 PGI(2), in the regulation of both innate and acquired immunity.

14 identical to corresponding maximal naturally acquired immunity.

15 gen dissemination and for the development of acquired immunity.

16 he spleen and are major targets of naturally acquired immunity.

17 te effector mechanisms, and the induction of acquired immunity.

18 required for optimal induction of protective acquired immunity.

19 e system that contributes to both innate and acquired immunity.

20 provide a means of enhancing both innate and acquired immunity.

21 providing a critical link between innate and acquired immunity.

22 d a major connecting link between innate and acquired immunity.

23 which Abs play a critical role in naturally acquired immunity.

24 s provide a critical link between innate and acquired immunity.

25 can function as a bridge between innate and acquired immunity.

26 s, including receptor function in innate and acquired immunity.

27 , intracellular pathogenesis, and innate and acquired immunity.

28 ons, although they may contribute to partial acquired immunity.

29 ession plays a vital role both in innate and acquired immunity.

30 ereby controlling subsequent polarization of acquired immunity.

31 d to have a critical role in both innate and acquired immunity.

32 poietic rescue but also augmented innate and acquired immunity.

33 Leptin plays a role in innate and acquired immunity.

34 ge, it is not known if LNs are essential for acquired immunity.

35 st defense burden from an innate response to acquired immunity.

36 on and may bridge the gap between innate and acquired immunity.

37 ccharide contribute to evasion of innate and acquired immunity.

38 -like cytokines that help mediate innate and acquired immunity.

39 matic mutation is a fundamental component of acquired immunity.

40 cules which contribute to the development of acquired immunity.

41 les in host defence and in the regulation of acquired immunity.

42 infection, mice were rechallenged to assess acquired immunity.

43 ve incidence rates and evaluate evidence for acquired immunity.

44 to determine their contribution to naturally acquired immunity.

45 lex immunomodulatory functions in innate and acquired immunity.

46 ibility to malaria by compromising naturally acquired immunity.

47 olonization and the acquisition of naturally acquired immunity.

48 several immune responses in both innate and acquired immunity.

49 gulating homeostatic immune architecture and acquired immunity.

50 but we lack an understanding of the role of acquired immunity.

51 sed health care workers and in patients with acquired immunity.

52 shaping protection or pathogenic sequelae of acquired immunity.

53 aft survival by suppressing inflammation and acquired immunity.

54 ptible to infection regardless of previously acquired immunity.

55 NF-kappaB plays a key role in innate and acquired immunity.

56 ating and inhibitory functions on innate and acquired immunity.

57 n immune function, involving both innate and acquired immunity.

58 cells (DCs) are key regulators of innate and acquired immunity.

59 on is associated with reduction in naturally acquired immunity.

60 lymphocyte responses and bridges innate and acquired immunity.

61 enes that play essential roles in innate and acquired immunity.

62 osal surfaces, thus directing and regulating acquired immunity.

63 is a key event in the control of innate and acquired immunity.

64 mental antigens (memory response) is termed "acquired" immunity.

65 ic settings with varying levels of naturally acquired immunity: a typical setting under which prevale

66 The Khmer migrants, with low acquired immunity, active on plantations and mines, repr

67 ibution of cross-priming to the induction of acquired immunity after DNA immunization.

68 two decades, and there is good evidence for acquired immunity after infection.

69 studying the roles of passively and actively acquired immunity against B. pertussis.

70 We investigated whether the presence of acquired immunity against E. phagocytophila precludes wh

71 Hence, Il6 is of critical importance for acquired immunity against M. tuberculosis infection.

72 e long been known to contribute to naturally acquired immunity against malaria, but their association

73 throcytes are important targets of naturally acquired immunity against malaria, but their high number

74 hat are important for stimulating innate and acquired immunity against protozoal pathogens.

75 conclusions about the strength of naturally acquired immunity against rotavirus gastroenteritis (RVG

76 nd might result in the undermining of normal acquired immunity against T. cruzi.

77 uncover a nonredundant role for basophils in acquired immunity against tick infection.

78 The relative contribution of acquired immunity against various stages of the parasite

79 tory protein that participates in innate and acquired immunity, also serves as a receptor for viral a

80 ytes (PE), plays a central role in naturally acquired immunity, although antibodies to PfEMP1 are pre

81 arum are an important component of naturally acquired immunity and an important vaccine target.

82 ll-like receptors (TLRs) activate innate and acquired immunity and are candidates for playing key rol

83 rulence factor that contributes to impairing acquired immunity and enhances susceptibility to reinfec

84 Acquired immunity and inflammation are likely to be cruc

85 ere mostly induced and related to innate and acquired immunity and inflammation.

86 r allergic reactions, but also for innate or acquired immunity and inflammatory conditions that worse

87 etent APC is essential for the generation of acquired immunity and is a major function of adjuvants.

88 measures the intensity of antimycobacterial acquired immunity and is used to diagnose latent infecti

89 d MSPDBL2 are important targets of naturally acquired immunity and might constitute potential vaccine

90 are complex and include host polymorphisms, acquired immunity and parasite virulence.

91 the context of the development of naturally acquired immunity and population infectivity.

92 cally infected euthymic mice, maintenance of acquired immunity and prevention of relapse required CD4

93 Acquired immunity and protective efficacy were also assa

94 Infection is maintained in spite of acquired immunity and resists eradication by antimicrobi

95 cuss recent advances in the understanding of acquired immunity and susceptibility to the two major pe

96 The primary site of expression of acquired immunity and the hallmark of tuberculosis is th

97 produced during the activation of innate and acquired immunity, and are the principal means for inter

98 demiology, diagnostics, disease attribution, acquired immunity, and innate susceptibility, and the gr

99 The complement pathway mediates innate and acquired immunity, and its activation drives the removal

100 to malaria among older children due to lower acquired immunity, and this has implications for ongoing

101 Innate and acquired immunity are critical in control of WNV, and in

102 Both innate and acquired immunity are likely to contribute to FCAVD.

103 biomarkers of malaria exposure and naturally acquired immunity are warranted in endemic settings wher

104 appear to play important roles in innate and acquired immunity as sensors of bacterial components.

105 lays a more pivotal antiviral role than does acquired immunity, as the antitumor effect of an oncolyt

106 ction of Abs arising in vaccine or naturally acquired immunity, as well of therapeutic mAbs.

107 therapy in Uganda are primarily mediated by acquired immunity associated with malaria transmission i

108 early in B. bronchiseptica infection and by acquired immunity at later time points and suggest that

109 ages play a critical role in both innate and acquired immunity because of their unique ability to int

110 ay also play a key role in the regulation of acquired immunity, because CR2 is mainly localized on B

111 mmunity and instructs the development of the acquired immunity but also leads to the detrimental infl

112 stem plays a central part in both innate and acquired immunity, but the contribution of complement ac

113 hese results indicate that activation of the acquired immunity by a periodontal pathogen reduces the

114 ut infection and can limit the expression of acquired immunity by a variety of pathways.

115 mmatory sites may restrain the activation of acquired immunity by blocking DC development and migrati

116 e host infections in some individuals versus acquired immunity by others, using complex metapopulatio

117 hese results indicate that activation of the acquired immunity by P. gingivalis increases the inflamm

118 Zinc deficiency also affects development of acquired immunity by preventing both the outgrowth and c

119 an important role for this T-cell subset in acquired immunity conferred by M. bovis BCG vaccination.

120 CD4(+) T-cell-dependent acquired immunity confers antibody-independent protectio

121 of CD169(+) macrophages in the activation of acquired immunity could benefit the design of vaccinatio

122 Vertebrate acquired immunity could have therefore originated from l

123 a disease for which there is no evidence of acquired immunity could prove extremely costly in the lo

124 of the Tag7-Hsp70 complex and TNF-alpha, an acquired immunity cytokine.

125 thin this region of CS, suggesting naturally acquired immunity does induce variant-specific selection

126 ry neuropeptides that affect both innate and acquired immunity, down-regulate IL-12 p40 and inducible

127 veloped a model that allows visualization of acquired immunity during and following antibiotic treatm

128 ave been preadaptations for the evolution of acquired immunity during the early vertebrate radiation.

129 tal role at the interface between innate and acquired immunities following their recruitment to infla

130 bacterial infection, but the acquisition of acquired immunity following successful treatment has rar

131 tes from NK-depleted animals transferred the acquired immunity generated with C3L5-CK beta 11 vaccina

132 Although acquired immunity has been shown to be crucial during CH

133 bsets in response to mediators of innate and acquired immunity have also been found in plaques.

134 oderma and provide support for the idea that acquired immunity helps to control naturally occurring c

135 lassic signaling is important for innate and acquired immunity, IL-6 trans-signaling has been linked

136 a relationship could be demonstrated between acquired immunity in experimental rabbit syphilis, serum

137 Characterisation of protective helminth acquired immunity in humans or experimental models has f

138 IFN-gamma, was necessary for suppression of acquired immunity in Rag(-/-) reconstituted mice.

139 and suggests either undetected infection or acquired immunity in the absence of infection.

140 ique opportunities for augmenting innate and acquired immunity in the human newborn.

141 ally contribute to early stages of naturally acquired immunity in the owl monkey model.

142 dence for the involvement of both innate and acquired immunity in the pathogenesis of AA.

143 udies have begun to elucidate differences in acquired immunity in tissues of the human female reprodu

144 MHC loci encode peptides that initiate acquired immunity in vertebrates, making them likely can

145 by affecting multiple aspects of innate and acquired immunity, including interfering with complement

146 ltiple effector cells of innate immunity and acquired immunity, including macrophages, dendritic cell

147 e the virulence, inflammatory potential, and acquired immunity induced by strains producing underacyl

148 is that aberrant activation or regulation of acquired immunity is central to the pathogenesis of this

149 essure toward antigenic variation exerted by acquired immunity is counterbalanced by a survival advan

150 eisseria meningitidis evades host innate and acquired immunity is crucial.

151 sis that the slow development of schistosome-acquired immunity is due to the slow accumulation of res

152 Furthermore, CD4+ and CD8+ T-cell-dependent acquired immunity is essential for long-term survival of

153 herefore, acquisition of strain-specific age-acquired immunity is partially directed against polymorp

154 dies of human disease suggest that naturally acquired immunity is the predominant outcome of Leishman

155 The mechanism of acquired immunity is unknown.

156 e of dendritic cells (DC) in both innate and acquired immunity is well recognized in the mammalian im

157 ansmissibility and the duration of naturally-acquired immunity, is essential in estimating the impact

158 oid cells with important roles in innate and acquired immunity: macrophages, mast cells and neutrophi

159 cted subcutaneously into cattle and that the acquired immunity markedly enhanced resistance to experi

160 uption of cells important in both innate and acquired immunity may contribute to the overall immune d

161 ely susceptible BALB/c mice, suggesting that acquired immunity may play an important secondary role.

162 alence tend to have high levels of naturally acquired immunity (NAI) to severe malaria; NAI is caused

163 er-induced CNV is not primarily dependent on acquired immunity, nor does the fundus injury affect per

164 neage play a central role in both innate and acquired immunity of the host.

165 the host for life in the presence of strong acquired immunity, often exhibiting periodic reactivatio

166 To account for the possible effects of acquired immunity on half-life, we used three surrogates

167 ence of infection/disease or the patterns of acquired immunity or innate resistance to norovirus.

168 ts suggest that immune cells associated with acquired immunity play a role in regulating motoneuron s

169 atabodies) could degrade toxic proteins, but acquired immunity principles have not provided evidence

170 onella may interfere with the development of acquired immunity, providing insights into the complex n

171 .In addition to these developments regarding acquired immunity, refinements to our understanding of i

172 rf7 and Cxcl9; 7 and 60 days post infection, acquired immunity-related genes, such as Cd3g and H2-Aa;

173 Naturally acquired immunity results in a 69% reduction in the risk

174 ution of B-1a and B-1b subsets to innate and acquired immunity reveals an unexpected division of labo

175 st that malaria vaccines mimicking naturally acquired immunity should ideally induce antibody respons

176 Furthermore, autophagy is involved in acquired immunity, such as antigen processing for MHC II

177 the innate immune response to UPEC stimulate acquired immunity that facilitates enhanced clearance up

178 at Chlamydia trachomatis infection engenders acquired immunity, the basis for which is incompletely d

179 rotypes can circumvent preexisting naturally acquired immunity to AAV.

180 n of antibody responses with both innate and acquired immunity to amebiasis indicate that CD4+ T cell

181 that TH1 polarization has a primary role in acquired immunity to C. jejuni.

182 This review describes the generation of acquired immunity to C. trachomatis and focuses on how T

183 ia are common, which suggests that naturally acquired immunity to CMV does not alter shedding pattern

184 at Russian adults, who were unlikely to have acquired immunity to diphtheria through immunization or

185 Naturally acquired immunity to HSV involves T cell recognition of

186 sting that the extremely slow development of acquired immunity to human schistosomes may depend on ex

187 ortant sources of interferon (IFN)-gamma for acquired immunity to intracellular pathogens, but they c

188 Naturally acquired immunity to malaria develops slowly, requiring

189 Acquired immunity to malaria develops with increasing ag

190 Acquired immunity to malaria is inefficient, even after

191 understanding of the mechanisms of naturally acquired immunity to malaria may lead to insights for va

192 ng in the spleen, are thought to orchestrate acquired immunity to malaria, but it is not known how th

193 ought to play an essential role in naturally acquired immunity to malaria.

194 is understanding the mechanisms of naturally acquired immunity to malaria.

195 ily of clonally variant targets of naturally acquired immunity to malaria.

196 elerate efforts to unravel the mechanisms of acquired immunity to malaria.

197 omewhat impaired in their ability to develop acquired immunity to MoPn, again indicating a role for t

198 Acquired immunity to murine Chlamydia trachomatis genita

199 pecific immunity stabilizes competition, and acquired immunity to noncapsular antigens reduces fitnes

200 DBPII and implicate this molecule in partial acquired immunity to P. vivax in endemic populations.

201 DBPII and implicate this molecule in partial acquired immunity to P. vivax in populations in endemic

202 antibody responses to DBP correlate with age-acquired immunity to P. vivax, antibodies to recombinant

203 rtant yet understudied effector mechanism in acquired immunity to PAM.

204 Elucidating the mechanisms of naturally acquired immunity to Plasmodium falciparum infections wo

205 It is unclear whether naturally acquired immunity to Plasmodium falciparum results from

206 Naturally acquired immunity to Plasmodium falciparum's asexual blo

207 ABTs clear pneumococcal colonization or that acquired immunity to pneumococci is an accumulation of i

208 the virus to reinfect individuals that have acquired immunity to previously circulating strains thro

209 nsistent with cooperation between innate and acquired immunity to promote a pattern of homing recepto

210 ng that gammadelta T cells can contribute to acquired immunity to S. dublin.

211 nt study we evaluated the role of B cells in acquired immunity to Salmonella infection by using gene-

212 suggest that the primary role of B cells in acquired immunity to Salmonella is via the development o

213 Acquired immunity to Streptococcus pneumoniae (pneumococ

214 antigens have been associated with naturally acquired immunity to symptomatic malaria.

215 eating a long-term, disease-free state, with acquired immunity to the tumor functioning as an essenti

216 l for the study of infection and vaccination-acquired immunity to this agent.

217 parum malaria in part by enhancing naturally-acquired immunity to this disease.

218 A thorough understanding of acquired immunity to ticks is essential for rational dev

219 T cells may play a role in innate as well as acquired immunity to tumors and infectious pathogens.

220 However, its role in regulating acquired immunity to viral pathogens and neuropathogenes

221 bility that extend from classical innate and acquired immunity to weaknesses in constitutional resist

222 pational exposure to HBV and in patients who acquired immunity via HBV infection.

223 Evidence of acquired immunity was observed among GII infections only

224 rom that of wild-type cells, confirming that acquired immunity was required for clearance in C3H/HeN

225 Immune components necessary for this acquired immunity were identified.

226 s in malaria transmission decrease naturally acquired immunity, which may influence the emergence of

227 , accelerating the development of protective acquired immunity, which would take many years to develo

228 or nonspecific activation of both innate and acquired immunity will be necessary for further developm