1 ring octreotide, studies were performed in 5 acromegalics.

2 LBTTs) in 4 groups of 8 individuals: (1) non-acromegalic controls, (2) acromegalics untreated with oc

3  acromegalics untreated with octreotide, (3) acromegalics on long-term octreotide, and (4) patients w

4 , all GH-producing adenomas originating from acromegalic patients demonstrated up-regulation of GHRH-

5 mass and thickness in myocardial biopsies of acromegalic patients, in which IGF-1 is overproduced aft

6 rol gallstones-including those developing in acromegalics treated with octreotide.

7 ific analog also exclusively inhibited GH in acromegalic tumor cells.

8 dividuals: (1) non-acromegalic controls, (2) acromegalics untreated with octreotide, (3) acromegalics