ライフサイエンスコーパス: acrosome reaction

1 etected in sperm after acrosomal exocytosis (acrosome reaction).

2 a role for these proteins in regulating the acrosome reaction.

3 gone associative changes during or after the acrosome reaction.

4 the sperm for an exocytotic process known as acrosome reaction.

5 hange in twist of actin filaments during the acrosome reaction.

6 rm to eggs or to induce sperm to undergo the acrosome reaction.

7 increase intracellular Ca(2+) and induce the acrosome reaction.

8 hyperactivated motility, chemotaxis, and the acrosome reaction.

9 and are thus well positioned to regulate the acrosome reaction.

10 dent EGFR activation, Ca(2+) influx, and the acrosome reaction.

11 is key to enabling mice sperm to undergo the acrosome reaction.

12 mines their expansion and the success of the acrosome reaction.

13 signal transduction necessary to trigger the acrosome reaction.

14 ractivated motility, and are readied for the acrosome reaction.

15 sting the involvement of a SRC kinase in the acrosome reaction.

16 n the inner acrosomal membrane following the acrosome reaction.

17 ed on the inner acrosomal membrane after the acrosome reaction.

18 ucida and undergo a Ca(2+) ionophore-induced acrosome reaction.

19 lation as well as the zona pellucida-induced acrosome reaction.

20 st of the spermatozoa undergoing a premature acrosome reaction.

21 previously characterized involvement in the acrosome reaction.

22 at is released from abalone sperm during the acrosome reaction.

23 pathway and that this drives the exocytotic acrosome reaction.

24 and active in sperm after activation by the acrosome reaction.

25 sion events during fertilization, namely the acrosome reaction.

26 ovide calmodulin at specific sites after the acrosome reaction.

27 sicle, whose contents are exposed during the acrosome reaction.

28 a role of voltage-sensitive Ca2+ channels in acrosome reactions.

29 ective fluorescent probes, and also inhibits acrosome reactions.

30 ssive motility, hyperactivated motility, and acrosome reactions.

31 phoinositide in the absence of ZP3 triggered acrosome reactions.

32 the zona pellucida (ZP), and fewer underwent acrosome reactions.

33 a role in ZP3-evoked Ca2+ influx that drives acrosome reactions.

34 2+) concentration in mouse sperm, leading to acrosome reactions.

35 taining an alpha7 subunit in the human sperm acrosome reaction (a modified exocytotic event essential

36 During the acrosome reaction, a 60-microm long coiled and twisted b

37 Because the acrosome reaction, a prelude to binding, is known to be

38 ion occurs after the completion of the sperm acrosome reaction, a secretory event that is triggered d

39 da glycoproteins, and once bound undergo the acrosome reaction, a type of cellular exocytosis.

40 This membrane is exposed after the acrosome reaction, an exocytosis event that occurs upon

41 arization, which is required for the ensuing acrosome reaction, an exocytotic process essential for f

42 atorial segment of spermatozoa following the acrosome reaction and a role for mSLLP1 in sperm-egg bin

43 ability of the zona pellucida to induce the acrosome reaction and by successful fertilization in vit

44 ertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the egg.

45 tents, and SNARE antibodies inhibit both the acrosome reaction and fertilization, without inhibiting

46 rane of the human spermatozoan following the acrosome reaction and may play a role in fertilization.

47 and sufficient to prepare the sperm for the acrosome reaction and suggest that changes in sperm memb

48 c inhibition also blocks the agonist-induced acrosome reaction and that this inhibition is overcome b

49 ylinositol-3-kinase antagonists that prevent acrosome reactions and fertilization in vitro, while gen

50 hyperactivation, the zona pellucidae-induced acrosome reaction, and most importantly, fertilization w

51 to bind soluble ZP3, undergo the ZP3-induced acrosome reaction, and penetrate the zona pellucida.

52 lar Ca(2+) leading to sperm hyperactivation, acrosome reaction, and perhaps chemotaxis toward the egg

53 m motility, chemotaxis, capacitation and the acrosome reaction, and play a vital role in the ability

54 the sperm's ability to swim and undergo the acrosome reaction, and thus redistribution of surface pr

55 logy, ability to undergo capacitation or the acrosome reaction, and/or mitochondrial membrane potenti

56 The sea urchin sperm acrosome reaction (AR) is a prerequisite for sperm-egg f

57 The mammalian sperm acrosome reaction (AR) is essential to fertilization, an

58 ilization, egg jelly (EJ) triggers the sperm acrosome reaction (AR) which is required for sperm bindi

59 The mammalian sperm acrosome reaction (AR), an essential fertilization event

60 Sea urchin egg jelly (EJ) triggers sperm acrosome reaction (AR), an exocytotic event required for

61 FSP induces the sperm acrosome reaction (AR), an exocytotic process required f

62 During fertilization, the sea urchin sperm acrosome reaction (AR), an ion channel-regulated event,

63 Intact sperm were evaluated before the acrosome reaction (AR), and a soluble form of PH-20 rele

64 y has been shown to be involved in the sperm acrosome reaction (AR), but the molecular identity of PL

65 One event, the sea urchin sperm acrosome reaction (AR), is blocked by the lectin wheat g

66 The exocytotic acrosome reaction (AR), which is required for fertilizat

67 (ZP) via sperm receptor(s) and undergoes an acrosome reaction (AR).

68 itation, hyperactivation of motility and the acrosome reaction are all mediated by increases in intra

69 ZP3 binding and subsequent induction of the acrosome reaction are dispensable for fertilization, the

70 In mammals, acrosome reactions are triggered during sperm contact wi

71 ne phosphorylation and the ionophore-induced acrosome reaction as well as luteinizing hormone, follic

72 concentrations inhibited the agonist-induced acrosome reaction as well as the increase in [Ca(2+)](i)

73 we show that Rab27 is also required for the acrosome reaction, as demonstrated by the inability of i

74 Acrosome reaction, binding to zona pellucida and fusion

75 [Ca(2+)](i) oscillations did not induce acrosome reaction, but in cells generating oscillations,

76 It has been suggested that ZP3 induces the acrosome reaction by crosslinking GalTase, activating a

77 e ability to undergo a zona pellucida-evoked acrosome reaction, develops more slowly in sperm from Pk

78 Induction of the acrosome reaction does not appear to alter the molecular

79 s by endogenous sialidases after a premature acrosome reaction during acute epididymitis.

80 released by regulated exocytosis (termed the acrosome reaction) during fertilization or on exposure t

81 be involved in sperm capacitation and/or the acrosome reaction, essential steps in fertilization wher

82 glycoprotein, ZP3, and as an inducer of the acrosome reaction following ZP3-dependent aggregation.

83 sociated with capacitation, induction of the acrosome reaction, forward velocity, or percentage of mo

84 ly to ZP3 and fail to undergo a zona-induced acrosome reaction; however, they still bind to the ovula

85 ptide is able to induce sperm to undergo the acrosome reaction (i.e., cellular exocytosis) in vitro.

86 Cells undergoing an acrosome reaction in aggregations remote from the egg ar

87 (2+) channels, inhibits progesterone-induced acrosome reaction in human sperm, but fluorimetric studi

88 ld-type sperm, and are unable to undergo the acrosome reaction in response to either ZP3 or anti-gala

89 asting conditions, autophagy regulation, the acrosome reaction in sperm, cancer cell migration, and i

90 ation of hundreds of fusion pores during the acrosome reaction in spermatozoa and the mobilization of

91 actions during and immediately following the acrosome reaction in the mouse.

92 r activity) and induces sperm to undergo the acrosome reaction in vitro at about the same concentrati

93 imals must complete an exocytotic event, the acrosome reaction, in order to fuse with eggs.

94 tion was sufficient to prepare sperm for the acrosome reaction induced either by depolarization with

95 membranes were permeabilized by fixation or acrosome reactions induced by the ionophore A23187, zona

96 The steroid progesterone, an agonist of acrosome reaction, induces a biphasic [Ca(2+)](i)-signal

97 The sperm acrosome reaction is a Ca(2+)-dependent exocytotic event

98 The sperm acrosome reaction is a Ca(2+)-dependent secretory event

99 The acrosome reaction is a unique exocytotic event involving

100 by removing a C-terminal fragment during the acrosome reaction, might be a mechanism to regulate the

101 In contrast, gt(-/-) sperm undergo the acrosome reaction normally in response to calcium ionoph

102 Motility, chemotaxis, and the acrosome reaction of animal sperm are all regulated by c

103 During the 5 s of the acrosome reaction of Limulus polyphemus sperm, a 60-micr

104 The metabolism, flagellar beating, and acrosome reaction of spermatozoa are regulated by ion fl

105 Sperm SNAREs are sloughed off during the acrosome reaction, paralleling the release of sperm memb

106 lvement of SNAP-25 in the invertebrate sperm acrosome reaction, possibly through increased associatio

107 o resulted in spermatozoa displaying reduced acrosome reaction potential.

108 Mammalian spermatozoa must complete an acrosome reaction prior to fertilizing an oocyte.

109 ty of gt(-/-) sperm to undergo a ZP3-induced acrosome reaction renders them physiologically inferior

110 However, during the acrosome reaction, Sp17 is processed from a 22- to 24-kD

111 lation inhibited the acetylcholine-initiated acrosome reaction, suggesting the involvement of a SRC k

112 lthough this complex is present prior to the acrosome reaction, the amount of complex increases over

113 bundle is more than sufficient to power the acrosome reaction through the egg envelope.

114 alyzed for its involvement in triggering the acrosome reaction using a TPCN1 gene-deficient mouse str

115 ults in the release of SNAP-25 with the shed acrosome reaction vesicles.

116 Because a premature acrosome reaction was observed in an UPEC epididymitis m

117 posterior head plasma membrane following the acrosome reaction, when it functions in sperm-egg intera

118 one causes a single large transient (causing acrosome reaction) which is apparently dependent upon Ca

119 coat of the egg (egg jelly), triggering the acrosome reaction, which transforms the sperm into a fus

120 y increased sensitivity to ionophore-induced acrosome reactions without undergoing capacitation in vi