ライフサイエンスコーパス: act in

1 oved was 136 from 1970 to the enactment of the Hatch-Waxman Act in 1984; 284 from 1985 to the enactment of the Generic Dr

2 284 from 1985 to the enactment of the Generic Drug User Fee Act in 2012; and 588 from 2013-2018.

3 player in the fragmentation of plasma DNA, which appears to act in a cell-extrinsic manner to regulate plasma DNA size an

4 scripts targeted by RsmA, and suggest that RsmA and Hfq may act in a combinatorial fashion on certain transcripts.

5 vestigated the hypothesis that these epigenetic alterations act in a feed-forward fashion to promote aberrant DNA methyla

6 show in mice that the signalling molecules RSPO1 and RSPO3 act in a functionally redundant manner to permit WNT/beta-cat

7 An ability to act in a goal-directed manner is progressively refined during

8 peutic potential of cytomegalovirus-specific (CMV-specific) ACT in an adjuvant setting for patients with primary GBM, wit

9 We demonstrate that the ADR1 and NRG1 families act in an unequally redundant manner in basal resistance, eff

10 ilst associated with the maintenance of plasmids, they also act in bacterial immunity and antibiotic tolerance.

11 These findings suggest PGs act in both the border cells and nurse cells, the substrate o

12 archical and coordinated manner in which genes and pathways act in cancer cells to orchestrate their evasion of CTLs, and

13 anism, whereby a group of neurons, each with local effects, act in combination to elicit a global motor response.

14 Furthermore, D2R and D3R act in combination to mediate dopaminergic inhibition of GSIS

15 cts of the many different factors or to understand how they act in combination.

16 Thus, the membrane and cytoskeleton act in concert in distinct subcellular compartments to drive

17 roject to the NAc, but it remains unknown whether dH and vH act in concert or separately to engage NAc representations re

18 How such compounds act in concert remains to be elucidated.

19 nt for sleep induction; instead, our data suggest that they act in concert to activate RIS.

20 , mostly depending on the structure of one particular loop, act in concert to determine Grx function.

21 gands and signalling pathways, it is not known whether they act in concert to drive pathological processes in COPD.

22 does not require selective interference, both processes may act in concert to further accelerate Y degeneration.

23 These effects likely act in concert to lower islet inflammation while increasing T

24 hat function in disparate biochemical pathways and can also act in concert to mediate a series of redox reactions.

25 hat altered neurotransmission and neuroimmune responses may act in concert to perturb behavior.

26 MicroRNAs (miRNAs) act in concert with Argonaute (AGO) proteins to repress targe

27 ted nets (ITNs), in addition to scenarios where gene drives act in concert with existing vector control tools such as ITN

28 pollution, drugs, cultural practices, and values, that all act in concert with our genetic architecture and biology.

29 xist in the biological system and that these components may act in coordination to regulate the internalization of cellul

30 The aim of this study was to ascertain whether hGrx1 can act in Cu delivery to the metal binding domains (MBDs) of the

31 eplication terminates and associates with proteins known to act in DNA replication.

32 may have the potential to improve the antitumor activity of ACT in humans through increased in vivo expansion and polyfun

33 iphosphate to increase the selectivity of such compounds to act in infected versus noninfected cells.

34 the chromatin-binding and enzymatic modules of UHRF1 do not act in isolation but interplay in a coordinated and regulated

35 The hippocampus is essential for normal memory but does not act in isolation.

36 lux-based approaches, it is now rather considered that they act in parallel and also that their relative contribution to

37 Since transcription factors (TFs) can act in part as the catalytic agents that determine the rates

38 This suggests that PDE4 inhibition may act in part through effects on the autonomic nervous system r

39 wide range of cellular functions, organizing molecules that act in processes ranging from RNA metabolism to signalling to

40 ions of unfairness and their tendencies to think, feel, and act in radicalizing ways.

41 Our data found CHH methylation to act in redundancy with symmetric methylation in silencing tra

42 These two enzymes act in series and possibly form a complex that efficiently co

43 ) cluster contains six microRNAs (miRNAs) that collectively act in several disease settings.

44 To identify other factors that act in the budding-yeast pathway, we performed an unbiased ge

45 he underlying molecular mechanisms of how phosphoinositides act in the ER stress response remain elusive.

46 Other planetary-scale waves and large-scale turbulence act in the opposite direction.

47 cosinolate-derived compounds, suggesting that PEN2 and PCS1 act in the same metabolic pathway.

48 rget sites, a network analysis revealed that some FIKKs may act in the same pathways.

49 starch granule initiation allows us to propose how SS5 may act in this process.

50 ver, additional analyses indicate that many local-eQTLs may act in trans instead.