ライフサイエンスコーパス: act through

1 Thus, mechanical forces act through a central feedback circuit between microRNA-

2 Axon guidance is proposed to act through a combination of long- and short-range attra

3 shear-dependent increases in ATP, which can act through a diverse portfolio of purinergic signaling

4 P) in the preabsorptive state, postulated to act through a gut-brain-liver axis involving accumulatio

5 replication and episome persistence and may act through a host cell partner(s) other than a BET prot

6 our findings suggest that endogenous NT may act through a local circuit to decrease presynaptic dopa

7 tic studies revealed that the lead compounds act through a mechanism distinct from that of traditiona

8 ted that many AF-associated genetic variants act through a mechanism of impaired muscle cell differen

9 ntegrity and that they therefore most likely act through a mechanism other than HI.

10 n of proatherogenic circulating factors that act through a meta-organismal endocrine axis to impact C

11 and larval developmental stages, where they act through a multi-faceted mechanism.

12 Dimerization did not act through a physical clustering-based kinase activatio

13 However, MSCs appear to act through a seemingly limited "hit-and-run" mode to qu

14 neuroprotective properties of microvesicles act through a trophic support mechanism that reduces inf

15 s sequence similarity with SynDIG1, it might act through a unique mechanism as an auxiliary factor fo

16 enetic studies suggest that these inhibitors act through a unique pH-sensing intersubunit interface i

17 ypes showed altered microtubule dynamics and acted through a dominant toxic gain of function mechanis

18 TGF-beta acted through a JNK-dependent, Smad4-independent pathway

19 S6K in turn acted through a negative feedback loop to restrain Akt3

20 efficacious and safer drugs, preferentially acting through a different mechanism of action and direc

21 lesterol-dependent apoptosis in podocytes by acting through a dual mechanism that required a reductio

22 sting that the Notch intracellular domain is acting through a novel mechanism.

23 at PGC1alpha suppresses melanoma metastasis, acting through a pathway distinct from that of its bioen

24 or human alertness and cognition, presumably acting through a photoreception system that heavily reli

25 ic maintenance of the intestinal epithelium, acting through a role that is independent of its iron-up

26 ding Ca(2+) sensitivity, Lys(580) presumably acting through a structure stabilization of the Ca(2+) b

27 into all cell types, whereas gH/gL/UL128-131 acts through a distinct mechanism to allow infection of

28 MET is a known proto-oncogene that acts through a diverse set of signaling pathways and is

29 e determined that PXR is expressed in liver, acts through a DNA response element located in the CYP3A

30 ntity in adult ovarian somatic cells, but it acts through a Dsx(M)-independent mechanism.

31 r being upregulated by IL-1alpha, IL-36alpha acts through a feedback mechanism to boost IL-1alpha lev

32 The P22 stabilizing site acts through a local conformational change and a hydroph

33 n the ethylene and cytokinin pathways, which acts through a phosphorelay mechanism.

34 Similar to mammalian IL-10, carp Il10 acts through a signaling pathway involving phosphorylati

35 We propose a model in which drought acts through ABA to increase ABIG1 transcription which i

36 chanisms mediated by neutrophil-derived LTB4 act through activation of its receptor, B leukotriene re

37 Noradrenaline acts through adrenergic receptors (ARs), of which beta2-

38 sequestration of miR165/6, a conserved miRNA acting through AGO1.

39 inhibition, suggesting that the inhibitor is acting through AKT signaling pathways.

40 Mechanistically, mTORC2 acts through Akt to repress Raf1-MEK1/2-ERK1/2 signaling

41 eaching experiments, revealed that nicotine, acting through alpha7-containing nicotinic acetylcholine

42 results of this study suggest that nicotine acts through alpha7-nAChR and plays a novel role in the

43 Medications that act through alternative molecular mechanisms are critica

44 l ganglion cell (RGC) intrinsic excitability acting through AMPK-dependent inhibition of NKCC1 activi

45 Jmjd2b and Nanog act through an interconnected regulatory loop, whereas J

46 e and the motor state of head undulations by acting through an acetylcholine-gated channel and a musc

47 data reveal a new function for an S6 kinase acting through an AMP kinase in regenerative growth of i

48 dence that GM-CSF drives CCL17 production by acting through an IFN regulatory factor 4-dependent (IRF

49 cterized NDN as a potent anorexigenic signal acting through an uncharacterized endozepine G protein-c

50 dependence or reward behavior, suggesting it acts through an alternative mu-opioid receptor target.

51 ndent inhibition of lateral root development acts through an EIN2-independent mechanism.

52 ponse pathway in Caenorhabditis elegans that acts through an evolutionarily conserved motif, termed E

53 cium-activated protein for secretion (CAPS)] acts through an inhibitory pathway not explained by prev

54 We demonstrate that H2O2 acts through an Src kinase to activate a negative regula

55 Further analysis revealed that SKI-417616 acts through antagonism of the host cell dopamine D4 rec

56 ovel APC:Axin interaction site, and (2) GSK3 acts through APC motifs R2 and B to regulate APC:Axin in

57 All of the genetic variants seem to act through atherosclerosis, except for the ABO blood gr

58 The plant signaling molecule auxin, acting through AUXIN RESPONSE FACTOR (ARF) transcription

59 Surprisingly, we find that 5-FU and FUDR act through bacterial ribonucleotide metabolism to elici

60 ing 40,758 interactions, of which two-thirds act through binding events located in DNase I hypersensi

61 We show that RdCVF acts through binding to Basigin-1 (BSG1), a transmembran

62 gE-mediated mechanisms, LMW agents appear to act through both immunological and non-immunological mec

63 The findings indicate I3C may be acting through both AHR-dependent and -independent mecha

64 interferon (IFN) response is controversial - acting through both positive and negative regulatory mec

65 These data suggest that GABA, acting through both presynaptic GABAA and GABAB receptor

66 a regulatory circuit involving FBXL5 and CIA acts through both IRPs to control iron metabolism and pr

67 feedback regulated by intracellular Ca(2+) , acting through calmodulin to facilitate channel opening.

68 vidence that rapamycin increased survival by acting through canonical pathways, including mitochondri

69 RPV1, causing local production of AEA, which acts through CB2.

70 CC chemokine ligand 18 (CCL18), acting through CC chemokine receptor 8 (CCR8) on mononuc

71 increasing endometriosis risk in this region act through CDC42, but further functional studies are re

72 Here we show that LAR-RPTPs act through cellular inhibitor of apoptosis protein 1 (c

73 We further find that NO acts through cGMP signalling in neurons to promote cell

74 We demonstrate that many edQTLs can act through changes in the local secondary structure for

75 CCHC14 and DNA methylation suggest the locus acts through changes to regulatory elements.

76 d may be considered an emergent "patchiness" acting through chemically identical ligand molecules.

77 Here, we report how Nek2 acts through cilia to influence LR patterning.

78 nd tumor cell survival, suggesting that both act through closely related mechanisms.

79 ctivators forms a hexameric AAA+ ATPase that acts through conformational changes brought on by ATP hy

80 ng evidence suggests that Polycomb complexes act through controlling spatial genome organization.

81 describes a cellular mechanism by which LEN, acting through CRBN and IKZF1, has cytotoxic effects in

82 ective antagonist CP-154526, suggesting Ucn1 acts through CRF-R1 when promoting chondrocyte survival.

83 pr or Vpx relies on CUL4A, CUL4B, or both to act through CRL4 is not known.

84 Nevertheless, different ligands acting through cross-wired pathways often lead to differ

85 egative regulation of virulence by GacS/GacA acts through csrB sRNA, which binds to CsrA and neutrali

86 ce light via phospholipase-C, apparently not acting through diacylglycerol.

87 iral RNA polymerase gene A24R, which seem to act through different mechanisms to increase virus repli

88 ple drugs that affect different pathways and act through different mechanisms, or combinations of dru

89 ficity to the different responses, it should act through different transduction pathways and/or in co

90 a novel epigenetic silenced tumor suppressor acting through direct regulation of p53 transcription an

91 emes, and that cholesterol-modified Hedgehog acts through Dispatched to increase cytoneme occurrence.

92 us, different combinations of Dscam proteins act through distinct mechanisms in closely related neuro

93 Therefore, although CX3CR1 and CX3CL1 act through distinct mechanisms in different pathologies

94 e (AC) activity relies on multiple effectors acting through distinct binding sites.

95 er in males than females, ecdysone signaling acts through distinct cell types and effectors to ensure

96 e that VOCs produced by P. polymyxa KM2501-1 act through diverse mechanisms to control M. incognita.

97 he gene-by-diet interactions on blood lipids act through DNA methylation.

98 e-by-fatty acid interactions on blood lipids act through DNA methylation.

99 Finally, we find that JH acts through dopaminergic neurons and conclude that an E

100 ttractive class of antimicrobial agents that act through dysregulation of caseinolytic protease (ClpP

101 a the non-canonical TGFbeta signaling branch acting through eIF4E phosphorylation.

102 th inhibition in MDMs, suggesting that IL-22 acts through enhanced phagolysosomal fusion.

103 e putative fast-onset antidepressants, which act through enhancement of mesocortical dopaminergic sig

104 tructive role for serotonin in axon guidance acting through ephrinB2a and reveal a novel mechanism fo

105 e transcripts are candidate targets of VAL1, acting through epigenetic and/or transcriptional repress

106 rovide a novel mechanism by which estrogens, acting through ER+ astrocytes in the brain microenvironm

107 a lesser extent 17alpha-estradiol, possibly acting through ER-X, prevented this effect.

108 17beta-estradiol (E2), acting through ERalpha, and pro-inflammatory cytokines,

109 We propose that E2, acting through estrogen receptor-beta, transactivates sy

110 t KTN0073 as a novel IgG2-based MET mAb that acts through exon 14-independent mechanisms to degrade t

111 ING LOCUS T (FT) and TERMINAL FLOWER1 (TFL1) act through FD and FD PARALOG to regulate the transition

112 idopsis thaliana), the photoperiodic pathway acts through FLOWERING LOCUS T (FT) to promote floral in

113 recruitment and appropriate host defense and act through G protein-coupled receptors (GPCRs), which i

114 , mechanical cues, and hormonal signals that act through G-protein-coupled receptors.

115 anging effects on many different cell types, acting through G-protein-coupled receptors such as LPAR6

116 of metabolites have signaling properties by acting through G-protein-coupled receptors.

117 n, and anxiety disorders such as depression, acts through G-protein-coupled receptors (GPCRs) known a

118 lectron microscopy, we suggest that GABA may act through GABA autoreceptors on HCs, thereby possibly

119 ecific to asymmetric division and whether it acts through Galpha to promote furrowing are unclear.

120 mu-Opioids act through GPCRs that are generated from the Oprm1 gene

121 our studies suggest that cytoskeletal forces acting through GPIbalpha are involved in maintaining pla

122 The KSHV-encoded vGPCR acts through Gq/11 and G12/13 to inhibit the Hippo pathw

123 clusters in cultured myotubes via PI3 kinase acting through GSK3beta.

124 FKBP51 acts through GSK3beta on the downstream targets Tau, bet

125 Mutant, truncated A20 proteins are likely to act through haploinsufficiency because they do not exert

126 re, repression of TGFbeta signaling by Notch acting through HEYL may promote initiation of breast can

127 ression of odorant receptor genes and likely acts through histone methylation to maintain the silence

128 echanistic investigations suggested that NmU acted through HSP27 as partner protein to stabilize HER2

129 2 TPR domain and supports a model where Swa2 acts through Hsp70, most likely to provide additional ac

130 Each of these neurohormonal derangements may act through increased activity of both NHE1 and NHE3.

131 re consistent across the cortical hierarchy, acting through increased and stabilized neuronal excitab

132 that, in these models, SAR-20347 is probably acting through inhibition of TYK2.

133 We demonstrated that ebselen acts through inhibition of protein synthesis and subsequ

134 Here, we show that TIMP3 acts through inhibition of the metalloprotease ADAM17 an

135 Acting through intestinal bHLH-PAS domain proteins Metho

136 icate corticotropin-releasing hormone (CRH), acting through its CRH1 receptor, in stress- and depende

137 hat the extracellular matrix protein Reelin, acting through its downstream, intracellular Dab1 and Sr

138 ophosphatidic acid (LPA) in decidualization, acting through its G-protein-coupled receptor LPA3 in th

139 Netrin-1, acting through its principal receptor DCC (deleted in co

140 ike weak inducer of apoptosis (TWEAK) ligand acting through its receptor, fibroblast growth factor-in

141 rogesterone suppresses uterine contractility acting through its receptors (PRA/B).

142 a post-transcriptional repressor of T cells, acting through its ROQ domain to destabilize mRNA target

143 by venous endothelium-derived endothelin-1, acting through its specific receptor Ednra expressed wit

144 The American Bar Association, acting through its Standing Committee on Gun Violence, c

145 on is a promoter of ischemic brain damage by acting through its target DNMT3a.

146 The secreted neurorepellent Slit2, acting through its transmembrane receptor, Roundabout (R

147 ed Ccn1(DeltaHep) mice, indicating that CCN1 acts through its alpha6beta1 binding sites in this conte

148 potent growth and metastasis suppressor that acts through its inhibitory effects on a wide variety of

149 jor regulator is thyroid hormone (TH), which acts through its nuclear receptor (TR) to induce the exp

150 Hakai acts through its phosphotyrosine-binding (HYB) domain, w

151 olic switch upregulate interleukin 33, which acts through its receptor ST2 to activate both choroidal

152 F-related weak inducer of apoptosis (TWEAK), acts through its receptor, fibroblast growth factor-indu

153 We demonstrated that glutamate acts through kainic acid receptors in the VMH to augment

154 ays; moreover, the compound does not seem to act through kinase inhibition.

155 Genetic analyses further confirm that lin-42 acts through let-7 family miRNAs.

156 Long-range corticocortical projections thus act through local microcircuits to exert spatially speci

157 These results establish that NNI2 inhibitors act through long range allosteric effects, reveal import

158 lts suggest that KAP1 Ser473 phosphorylation acts through MFN2 reduction to restrict mitochondrial hy

159 on of multivesicular release, P/Q-type VGCCs act through microdomain signaling to recruit additional

160 le in mammary tumorigenesis and progression, acting through miR-221 in cooperation with known oncogen

161 e-like cells stimulated with mOSM (therefore acting through mLIFR), microarray expression profiling a

162 in a number of learning paradigms, probably acting through modulation of multiple neurotransmitter s

163 Although almost all clinically used drugs act through mu opioid receptors, they display subtle but

164 nt of severe pain depends heavily on opioids acting through mu opioid receptors encoded by the Oprm1

165 during evolution, a transcription factor can act through multiple mechanisms to generate a common beh

166 the notion that pathogen virulence effectors act through multiple targets in host cells.

167 These results indicate that thrombin acts through multiple mechanisms to activate MMPs and PG

168 cally costly, a rise in intracellular Ca(2+) acts through multiple pathways to increase ATP synthesis

169 europilin combinations, we found that SEMA3F acts through multiple receptors, but predominantly requi

170 y during prolonged exposure to pheromone and acts through multiple substrates to down-regulate yeast

171 en together, these results suggest that S6K1 acts through multiple targets of the mTOR pathway to pro

172 target of NFkappaB and show that C3 release acts through neuronal C3aR to disrupt dendritic morpholo

173 Furthermore, AWB neurons act through neuropeptide signaling to regulate reproduct

174 laborative functions of IL-17 and IFN-gamma, acting through neutrophils and macrophages, respectively

175 ontribution of CypA as a pertinent component acting through NF-kappaB-Sox9 in regulation of chondroge

176 Moreover, we found that RAC1 acts through NF-kappaB to induce NRF2 because either exp

177 ugh ERalpha, and pro-inflammatory cytokines, acting through NFkappaB, increase the nascent transcript

178 Here, we identify a new pathway that acts through NIMA-related kinase 6 (Nek6) and Hsp72 to p

179 vents rescue by hUPF1, suggesting that hUPF1 acts through NMD to enhance survival.

180 (-/-) mouse, we demonstrate that type I IFNs act through nonepithelial cells, including macrophages,

181 elegans has an endogenous opioid system that acts through NPR-17, and that opioids regulate feeding v

182 nflammatory function of the compound largely acts through Nrf2.

183 cies surveyed, winter temperature appears to act through overwinter mortality of juveniles or as a cu

184 Enteric purinergic motor neurotransmission, acting through P2Y1 receptors (P2Y1R), mediates inhibito

185 g the NRF2-mediated induction of MDM2, which acts through p53-dependent and -independent mechanisms t

186 The activated Akt acted through phosphatidylinositol 3-phosphate 5-kinase

187 Specifically, elevated membrane tension acts through phospholipase D2 (PLD2) and the mammalian t

188 onzalez et al. (2016) show that PDGFA, which acts through PI3K-Akt pathways, plays a vital role in th

189 tabilized by biophysical feedback mechanisms acting through pore characteristics and microbial access

190 s cue-induced feeding, and suggest orexin is acting through prefrontal cortical and thalamic sites to

191 soned that the product of this gene, AtMSI4, acts through protein partners, which we have co-immunopu

192 The parathyroid glands acting through PTH play a critical role in the regulatio

193 mong the iron diets, suggesting that iron is acting through reactive oxygen species signaling.

194 the regulation of motor function and reward, acts through receptors mainly expressed in striatum as w

195 ding one tryptophan residue W127 that likely acts through regulating nucleic acid binding.

196 nd kinase (STRIPAK) complexes that appear to act through regulation of protein phosphatase 2A (PP2A),

197 chanosensory channel, suggests that OCRL may act through regulation of this channel.

198 tive regulator of developing axon extension, acting through repression of Rasa1 mRNA, in a mechanism

199 utants, suggesting that BLH6/KNAT7 signaling acts through REV as a direct target.

200 of the myosin light chain activation, RHGF-1 acted through Rho-dependent kinase LET-502/ROCK and acti

201 Mechanistically, Slit2 acting through Robo1 and Robo2 promoted the migration of

202 terpenes, particularly pinenes, promote SAR, acting through ROS and AZI1, and likely function as info

203 S1P acting through S1P2 and S1P3 receptors activated intrace

204 Thus, gut microbiota acting through SCFAs are important determinants of enter

205 are organized into autonomous subgroups and act through separate mechanisms.

206 inant of meiotic recombination hot spots and acts through sequence-specific DNA binding via its C2H2

207 As a consequence, a single peptide can act through several mechanisms depending on the peptide'

208 Many signaling pathways act through shared components, where different ligand mo

209 have been developed to study cellular forces acting through single mechano-sensitive receptors.

210 acid (LPA) is a natural bioactive lipid that acts through six different G protein-coupled receptors (

211 ercise-induced bronchoconstriction (EIB) and act through specific receptors (ADRB2).

212 ic impairment in the entorhinal cortex (EC), acting through specific cellular signaling.

213 lex binding to the Pygo chromatin reader and acting through TCF/LEF-responsive enhancers.

214 Vitamin C potentiates TET activity and acts through Tet2/Tet3 to increase the stability of Foxp

215 is an innate modifier of adult angiogenesis, acting through TGFbetaR1.

216 ered the underlying pathway: both treatments act through the A2b receptor and specifically activate t

217 se in local production of kynurenines, which act through the AHR to impair neutrophil chemotaxis.

218 Norepinephrine and CGRP act through the alpha(2)-adrenergic receptor and CGRP re

219 They act through the binding and release of substrate protein

220 (9)-tetrahydrocannabinol (THC), CBD does not act through the cannabinoid type 1 (CB1) receptor but ha

221 ed pheomelanin's pro-oxidant properties that act through the generation of reactive oxygen species an

222 ase in the STAT signaling pathway and do not act through the inhibition of STAT3 dimerization by the

223 by mouse macrophages, suggesting that it may act through the PAF/PAF receptor pathway previously show

224 phosphatases (Ssu72, Rtr1, and Fcp1), which act through the post-translational modification of the C

225 no acids are a key input to this system, and act through the Rag GTPases to promote the translocation

226 e to many cues, including amino acids, which act through the Rag guanosine triphosphatases (GTPases)

227 Dopaminergic agents might act through the reduction of latent inhibition, resultin

228 such as Z-d-Phe, are less effective but may act through the same mechanism.

229 However, whether AJs and Scrib act through the same or independent mechanisms to regula

230 oactive lipids (TXA2 and isoprostanes) which act through the thromboxane receptor (TP).

231 Instead, the compound is proposed to act through the transmembrane beta((+))/alpha((-)) subun

232 This health assurance acted through the regulation of the calcium-binding prot

233 This study establishes that macrophages, acting through the activation of the EGFR cascade, const

234 that gestational-choline supplementation is acting through the alpha7 nicotinic receptor to improve

235 Dioxin exposure, acting through the aryl hydrocarbon receptor (AHR), bloc

236 st that NLP7 controls the release of BLCs by acting through the cell wall-loosening enzyme CEL5.

237 regulate iTreg cell induction by dominantly acting through the CNS1 region of the Foxp3 locus.

238 vel regulator of WPB exocytosis, most likely acting through the downstream effectors ACAP2 and Arf6.

239 rks, with recent data showing that estrogen, acting through the estrogen receptor, can modulate initi

240 BA are important metabolic regulators acting through the farnesoid X receptor and TGR5 recepto

241 y was undertaken to identify common variants acting through the genotype of the affected individual (

242 radiation, and CPR-4 seems to exert RIBEs by acting through the insulin-like growth factor receptor D

243 Hippo kinase cascade is mediated by Hpo/Mst acting through the intermediary kinase Wts/Lats to phosp

244 y controlled by the luteinizing hormone (LH) acting through the LH/choriogonadotropin receptor (LHCGR

245 It is believed that 27HC, acting through the liver X receptor in macrophages and p

246 he lipid agonist lysophosphatidic acid (LPA) acting through the LPA receptor LPAR1.

247 gonists, notably lysophosphatidic acid (LPA; acting through the LPA1 receptor) and endothelin.

248 recognized as a key regulator of autophagy, acting through the modulation of pathways such as the me

249 been previously implicated as a general acid acting through the N1 position in other ribozymes such a

250 GDNF, acting through the receptor tyrosine kinase Ret, regulat

251 proteins with a wide array of functions and acting through the recognition of proline-rich sequences

252 the GFP-fused glucocorticoid receptor (GR), acting through the same HREs, displayed a profile consis

253 mechanism for the discrimination of ligands acting through the same receptor.

254 creased the proliferation of antitumoral M1, acting through the SEMA3A receptor neuropilin 1.

255 r caudal neural tube closure and elongation, acting through the transcriptional regulation of key tar

256 on brain-derived neurotrophic factor (BDNF) acting through the tropomyosin-related kinase receptor B

257 MAC1 acts through the 5' untranslated region of psaC transcri

258 We also demonstrate that the fragment acts through the alpha3beta1-integrin/extracellular matr

259 ity that ARF4-dependent polarized exocytosis acts through the basal body-ciliary complex to spatially

260 em cell factor (SCF) is a growth factor that acts through the c-Kit receptor tyrosine kinase to elici

261 oxia elevates expression of Cav1, which then acts through the calcium-binding protein S100P to promot

262 surface requires an S-phase checkpoint that acts through the DNA damage response (DDR) pathway, invo

263 that communication between these two domains acts through the endodermis.

264 TPase RAL-1, which localizes to vesicles and acts through the exocyst vesicle-tethering complex.

265 critical cardiac developmental peptide that acts through the G-protein-coupled apelin receptor, desp

266 ify CASTOR1 as a direct arginine sensor that acts through the GATOR2 complex to regulate mTORC1.

267 ry factor Enabled, and we find that Abl also acts through the GEF Trio to stimulate the signaling act

268 ical assays, we find that resveratrol indeed acts through the ICRF-187 binding locus, but that it inh

269 nnin and 3-methyladenine, suggesting that it acts through the mammalian target of rapamycin (mTOR)/PI

270 s an anti-inflammatory tumor suppressor that acts through the modulation of metabolism in the tumor s

271 Wnt4, in turn, acts through the noncanonical pathway to activate epithe

272 la cytokine, growth-blocking peptides (GBP), acts through the phospholipase C (PLC)/Ca(2+) signalling

273 data indicate that light at moderate levels acts through the plant's nuclear-localized sensory-photo

274 Our results support a model in which LsERF1 acts through the promotion of gibberellin biosynthesis t

275 Although it is well established that FGF19 acts through the receptor complex FGFR4-beta-Klotho (KLB

276 We identified a sizer protein, CDKG1, that acts through the retinoblastoma (RB) tumor suppressor pa

277 and various DDX1 mutants, we show that DDX1 acts through the RRE RNA to specifically accelerate the

278 rce of TGF-beta1 induced by local OPN, which acts through the transcription factor myeloid zinc finge

279 However, whereas BEC-1/BECN1/Beclin1 acts through the transcriptional regulator SKN-1/Nrf1, A

280 such as prednisone or deflazacort thought to act through their immunosuppressive properties.

281 C5a and C3a suppress IFN-beta production by acting through their respective receptors, because no in

282 Acting through these diverse signaling pathways, bile ac

283 o a key susceptibility gene for GD, probably acting through thymic-dependent central tolerance.

284 We conclude, BLP acting through TLR2, is a potent inducer of inflammation

285 ted with TLR4 inhibitor, indicating that MfP acts through TLR4.

286 iated with the detrimental effects of solTNF acting through TNFR1, while tmTNF promotes repair and re

287 Microbial stimuli, acting through Toll-like receptors, induced transforming

288 on our data, we propose a model in which TH acting through TRalpha1 and TRbeta1, respectively, fine

289 our data uncover an important role for DDR1, acting through Tuba and Cdc42, in proteolysis-based cell

290 parable to artemisinin and chloroquine while acting through two distinct mechanisms of action: oxidat

291 Platelet-derived growth factor (PDGF) acts through two conserved receptor tyrosine kinases: PD

292 These effects were dependent on IL-4 acting through type 2 IL-4 receptors on neutrophils.

293 enhancing release of BDNF that subsequently acts through tyrosine receptor kinase B (TrkB) receptor

294 brate-specific regulator of oocyte polarity, acting through unknown molecular interactions.

295 IL-17A acts through upregulation and stabilization of TGF-betaR

296 We propose the novel concept that IFN-gamma acts through upregulation of suppressor of cytokine sign

297 that lactate modulates neuronal excitability acting through various targets, including NMDA receptors

298 nosensitive junctional protein alpha-catenin acts through vinculin and Ena/VASP proteins to reinforce

299 iven tissue overgrowth and indicate that Ctp acts through Yorkie to control bantam (ban) and diap1 tr

300 that promotes the integrity of the Z ring by acting through ZapB and raises the possibility of the ex