ライフサイエンスコーパス: actin comet

1 ets, did not reconstitute dynamic, elongated actin comets.

2 nsport carriers in association with PI5K and actin comets.

3 d the morphology and dynamics of Nck-induced actin comets.

4 on on membrane-bound vesicles to form motile actin comets.

5 ine whether Dyn2 is an integral component of actin comets.

6 from membrane-bound vesicles to form motile actin comets.

7 nformation on the structural organization of actin comets and in particular the spatial arrangement o

8 hermore, the dsbA mutant was able to produce actin comets and protrusions, indicating its capacity fo

9 lacking VAP accumulate high levels of PI4P, actin comets, and trans-Golgi proteins on endosomes.

10 a constant velocity and were reminiscent of actin comets associated with motile vesicles in cells ex

11 Membrane internalization and actin comet formation are enriched in the anterior, and

12 Modulation of actin comet formation by pharmacologic means, by overexp

13 osphatidylinositol 5-kinase (PI5K) increased actin comet frequency in Madin-Darby canine kidney cells

14 teins of both dynamin 1 and 2, is present in actin comets generated by Listeria or by type I PIP kina

15 t PI(4,5)P(2) and PIP5K are both enriched at actin comets induced by Nck aggregates and that formatio

16 Nck knockdown or knockout suppressed actin comets induced by phosphatidylinositol 5-kinase (P

17 Actin comets may provide a novel mechanism for raft-depe

18 s suggest a previously unidentified role for actin comet-mediated propulsion in the biosynthetic deli

19 r coat nucleate the majority of the numerous actin comets present in patient cells.

20 Utilizing a Listeria fluorescent actin comet tail assay to monitor actin disassembly rate

21 er a mechanism for Shigella flexneri-induced actin comet tail elongation that links Abl family kinase

22 ate an important role for CRMP-1 in Listeria actin comet tail formation and open the possibility that

23 Actin comet tail formation and steady-state bacterial mo

24 o scored as an important factor for Listeria actin comet tail formation in brain cytosol.

25 Actin comet tail formation in vivo was stimulated by the

26 In addition, actin comet tail formation is associated with polarizati

27 tes N-WASP, a host cell protein required for actin comet tail formation, and mutation of the Abl phos

28 at the Abl kinases are required for Shigella actin comet tail formation, maximal intracellular motili

29 tes intracellular motility and spreading via actin comet tail formation.

30 hing minus retarding) force generated by the actin comet tail is approximately 0.4-4 nN.

31 SP overexpression caused loss of the typical actin comet tail shape induced by Nck aggregation.

32 ost proteins to assemble an Arp2/3-dependent actin comet tail to power its movement through the host

33 e slowly, the actin filaments comprising the actin comet tail were significantly more stable, with an

34 surface of every vesicle associated with an actin comet tail, suggesting that vesicle movement resul

35 ll actin to form the typical F (filamentous)-actin comet tail.

36 C3, DFCP1, and p62 through a WHAMM-dependent actin-comet tail mechanism.

37 plex for autophagosome biogenesis through an actin-comet tail motility mechanism.

38 marked increase in actin polymerization and actin comet tailing on GLUT4 vesicles.

39 eleton, displaying prominent accumulation on actin "comet tails" that emanate from focal adhesions in

40 N-WASP WH2 mutants assembled actin comet tails and initiated movement, but the comet

41 We find that motile vesicles associated with actin comet tails are significantly deformed due to an i

42 function we have simulated the structure of actin comet tails as well as the tracks adopted by bacul

43 otein Sla2p, patch motility was arrested and actin comet tails associated with endocytic patch comple

44 on, mimicking eukaryotic formins to assemble actin comet tails for Rickettsia motility.

45 cs that distinguish vesicles associated with actin comet tails from other vesicles in the extract.

46 Furthermore, vesicles associated with actin comet tails had the morphological features of mult

47 Several pathogens induce propulsive actin comet tails in cells they invade to disseminate th

48 this mixture was insufficient to disassemble actin comet tails in the presence of physiological F-act

49 cting protein 1 is sufficient to disassemble actin comet tails in the presence of physiological G-act

50 itutively active TC10 (TC10/Q75L) can induce actin comet tails in Xenopus oocyte extracts in vitro an

51 the leading edge of motile cells and in the actin comet tails of intracellular pathogenic bacteria a

52 ma S and sodium orthovanadate stimulation of actin comet tails on GLUT4 intracellular compartments.

53 solved the three-dimensional architecture of actin comet tails propelling baculovirus, the smallest p

54 escence recovery after photobleaching of the actin comet tails revealed that endocytic complexes are

55 strate that insulin can induce GLUT4 vesicle actin comet tails that are necessary for the efficient t

56 In addition, the insulin stimulation of actin comet tails was completely inhibited by Clostridum

57 Actin comet tails were often detected at the rear end of

58 filin can disassemble Listeria monocytogenes actin comet tails, it cannot efficiently disassemble com

59 tures, including podosomes, phagocytic cups, actin comet tails, subcortical ruffles, and stress fiber

60 ates the formation of Listeria monocytogenes actin comet tails, thereby implicating it in actin assem

61 n of Nck SH3 domains at the membrane induces actin comet tails--dynamic, elongated filamentous actin

62 odia and filopodia of migrating cells and in actin comet tails.

63 a S) and sodium orthovanadate stimulation of actin comet tails.

64 ared with bacterially associated cytoplasmic actin comet tails.

65 e formation and maintenance of Nck-dependent actin comet tails.

66 We show that the SNX9-driven actin comets that arise on human disease-associated ocul

67 uced by Nck aggregates and that formation of actin comets was strongly inhibited by coclustering with