ライフサイエンスコーパス: actin-binding

1 autophosphorylation states, also abolished F-actin binding.

2 PLP-containing ligands with little effect on actin binding.

3 he result of Mg(2+)-dependent alterations in actin binding.

4 e, that the mutant ABD retains high-affinity actin binding.

5 WH2 domains compete directly with MRTF-A for actin binding.

6 e enriched for cytoskeletal organization and actin binding.

7 f the tail domain of metavinculin (MVt) upon actin binding, a muscle-specific splice isoform that sup

8 ked ACTN4 mutant, K255E, which has increased actin binding activity and is predominantly cytoplasmic,

9 lear function of ACTN4 is independent of its actin binding activity in the cytoplasm.

10 large multidomain proteins that regulate the actin-binding activity of capping protein (CP), a major

11 f a GRE reporter while still maintaining its actin-binding activity.

12 eceptor ICAM-1 is negatively regulated by an actin-binding adaptor protein, i.e., CD2AP, to allow a b

13 es, we directly compared their G-actin and F-actin binding affinities, and quantified the actin filam

14 proteolysis experiments indicated a similar actin binding affinity and mode for both VT and MVT.

15 0.5 muM in U2OS cell cytosol, suggesting the actin-binding affinity measured here (Kd = 0.6 muM) is i

16 zone" must exist for each protein where the actin-binding affinity must be optimal for accumulation.

17 king proteins and identify a zone of optimal actin-binding affinity that allows for mechanical stress

18 g that the two heads of Myo5c-HMM increase F-actin-binding affinity.

19 ) was shown to cause a 1000-fold increase in actin-binding affinity.

20 redominantly in the heart, is a constitutive actin-binding alpha-catenin.

21 onserved C-terminal domains known to mediate actin binding and assembly while antagonizing actin-capp

22 ilament surface, making them unavailable for actin binding and ATP hydrolysis.

23 Dematin is a relatively low abundance actin binding and bundling protein associated with the s

24 yosin motor domain that are triggered upon F-actin binding and contribute critically to the mechanoch

25 D) of beta-III-spectrin causes high-affinity actin binding and decreased thermal stability in vitro.

26 inorganic phosphate (Pi), from dependency on actin binding and destroyed the ability of single dimeri

27 are conserved family proteins that regulate actin binding and endocytosis.

28 Collectively, our work suggests that both actin binding and MKlp2-dependent midzone targeting coop

29 cofilin-2-specific residues required for ATP-actin binding and propose that these residues function a

30 lly modulated via interaction with Ajuba, an actin binding and scaffolding protein.

31 rmation in the presence of calcium, enabling actin binding and severing.

32 f vertebrate cofilin at Ser-3 regulates both actin binding and severing.

33 cluding the exacerbation of Coro1A-dependent actin-binding and -bundling activities; the formation of

34 human genetic modifier plastin 3 (PLS3), an actin-binding and -bundling protein, fully protects agai

35 contributes to the mechanisms involving the actin-binding and -polymerizing proteins neural Wiskott-

36 The actin-binding and bundling protein, plastin 3 (PLS3), wa

37 linositol 3-kinase-AKT activation, cortactin-actin binding, and actin-associated cytoskeleton reorgan

38 egarding VCL(I997A), which also prevents VCL/actin binding, and VCL(A50I) and VCL(811-1066), both of

39 Cosedimentation, immunoprecipitation, and actin binding assays were used to study the functional c

40 Further, we demonstrate that the C-terminal actin-binding beta-sheet domain of CAP1 is sufficient to

41 Because PLS3 is an actin-binding/bundling protein, we hypothesized it would

42 Our findings shed light on modes of actin binding by cellular proteins and reveal how extrac

43 Our data suggest that high-affinity actin binding by SCA5 beta-spectrin interferes with spec

44 against models in which beta-catenin weakens actin binding by stabilizing inhibitory intramolecular i

45 sense mutation R431C in anillin (ANLN), an F-actin binding cell cycle gene, as a cause of FSGS.

46 cting with actin, the kinetic parameters for actin binding changed only slightly for the mutant const

47 The ADP-bound structure reveals that the actin-binding cleft is closed, even though MgADP is tigh

48 g, activating ABS2 and locking talin into an actin-binding configuration that stabilizes FAs.

49 phaT286D mutant, indicating that transient F-actin binding contributes to the synaptic localization o

50 its application to a brief synthesis of the actin-binding cytotoxin bistramide A.

51 Overexpression of ACTN4 and an actin binding-defective variant increases the reporter a

52 rrowing in MKlp2-depleted cells in an INCENP-actin binding-dependent manner.

53 We found that the VASP-F-actin binding domain is required for the recruitment of

54 se mutant Dyn1-K44A and the loss-of-function actin binding domain mutant Dyn1-K/E.

55 Dyn1 actin binding domain mutant inhibits filopodial formatio

56 -iLID can be used to temporally recruit an F-actin binding domain to MT plus ends and cross-link the

57 ne-rich domain and the binding of the VASP-F-actin binding domain to the side of growing filaments is

58 r ataxia type 5 (SCA5) L253P mutation in the actin-binding domain (ABD) of beta-III-spectrin causes h

59 he molecular conformation of alpha-actinin's actin-binding domain (ABD) regulates its association wit

60 ucine-to-proline substitution (L253P) in the actin-binding domain (ABD) was shown to cause a 1000-fol

61 at melanophilin, specifically its C-terminal actin-binding domain (ABD), is a target of PKA.

62 sophila S2 cells, anillin lacking the entire actin-binding domain (ActBD) exhibits defective cortical

63 nase domains are joined via a linker to an F-actin-binding domain (FABD).

64 model transmembrane protein with a cytosolic actin-binding domain also exhibits the temperature-indep

65 Shot interacts with the cortex through its actin-binding domain and recruits the microtubule minus-

66 tory intramolecular interactions between the actin-binding domain and the rest of alpha-catenin.

67 CryAB features a conserved actin-binding domain and, when attenuated, leads to clus

68 g of actin have been generated by fusing the actin-binding domain from an actin-interacting protein t

69 ow that MFM-associated ZASP mutations in the actin-binding domain have deleterious effects on the cor

70 The actin-binding domain is between the modular PDZ and LIM

71 n ACTN4 isoform, ACTN4 (Iso), that loses its actin-binding domain is still capable of potentiating a

72 The C-terminal actin-binding domain of alpha-catenin has no influence o

73 The function of the actin-binding domain of alpha-catenin, alphaABD, includi

74 on is observed independently of the proposed actin-binding domain of HIV-1.

75 The actin-binding domain of Shot directly interacts with Act

76 the first time that variants disrupting the actin-binding domain of SHROOM3 may cause podocyte effac

77 We constructed mice that lack the actin-binding domain of WIP (WIPDeltaABD mice).

78 Mutations in the actin-binding domain of ZASP-LDeltaex10, but not other i

79 complex, and the effect of the alpha-catenin actin-binding domain on beta-catenin association.

80 ant lacking the C-terminal calponin homology actin-binding domain stimulates actin branch formation b

81 n or coexpression of CaMKIIbeta carrying its actin-binding domain strongly modulated CaMKII diffusion

82 ain and the cargo adapter Mlph, which has an actin-binding domain that acts as a tether, are sensitiv

83 associate with F-actin through a conserved F-actin-binding domain, and mutants defective for F-actin

84 hila ortholog Filamin/cheerio that lacks the actin-binding domain, is here shown to govern the growth

85 ACTN2 c.683T>C (p.Met228Thr), located in the actin-binding domain, proved to be the only mutation ful

86 ease severing requires the internal (I/L)WEQ actin-binding domain.

87 regulatory headpiece domain followed by two actin-binding domains (ABD1 and ABD2).

88 Talin contains three actin-binding domains (ABDs).

89 Arg has two distinct actin-binding domains and interacts physically and funct

90 Both beta-cat- and actin-binding domains of alpha-cat are required to inhib

91 nal domain to wedge apart the membrane and F-actin-binding domains of ezrin.

92 We showed that the actin-binding domains of nesprin 1 were dispensable, whe

93 Remarkably, PLS3 mutants lacking both actin-binding domains were still able to rescue motor ax

94 Conversely, filamin that shares actin-binding domains with alpha-actinin had a strong in

95 In contrast, profilin that shares actin-binding domains with gelsolin, significantly incre

96 p7 subgroup of SNARE proteins [9] containing actin-binding domains, is a novel ER membrane-associated

97 nsable, whereas nesprin 1alpha2, which lacks actin-binding domains, was crucial for postnatal viabili

98 vely spliced so that each isoform has unique actin-binding domains.

99 GDP and GTP accelerate and decelerate Drp1/actin binding dynamics, respectively.

100 egion binds actin in vitro and that its main actin-binding element is the CT region, which does not i

101 g multiprotein complexes at the ankyrin- and actin-binding ends of spectrin.

102 interactions of RIOK3 with actin and several actin-binding factors including tropomyosins (TPM3 and T

103 ed a transgenic zebrafish line expressing an actin-binding green fluorescent protein in cardiomyocyte

104 secondary mechanism decreases the number of actin-binding heads transitioning from the weakly to the

105 ween the dimerization helices and the nearby actin-binding helical bundle.

106 Motor domain mutations that disrupt actin binding increased the mobility of full-length myos

107 In the first few nanoseconds, actin binding induced an extra primed myosin state, i.e.

108 initial powerstroke state, representing the actin binding-induced major structural changes in myosin

109 tion from the nucleotide pocket triggered by actin binding initiates myosin force generation.

110 resent here a myosin structure possessing an actin-binding interface and a tunnel (back door) that cr

111 provides the communication link between the actin-binding interface and the nucleotide pocket.

112 The Ca(2+)- and F-actin-binding leukocyte-specific protein 1 (LSP1) expres

113 thase, AMP-activated protein kinase, and the actin-binding MARCKS protein--was blocked by preincubati

114 ted C-C couplings enable construction of the actin-binding marine polyketide swinholide A in only 15

115 SORB-1 is recruited to the actin-binding, membrane-distal regions of dense bodies v

116 eity suggests that CaMKII adopts different F-actin binding modes, which is most easily rationalized b

117 tor activity, and an extended tail with tail actin-binding motif, allow it to play an important role

118 s an extended tail domain with an additional actin-binding motif.

119 s cell membranes to the cytoskeleton via its actin-binding motor domain and its phosphatidylinositol

120 ounts of Taxol rescues cytokinesis in INCENP actin-binding mutant-expressing cells.

121 ng lever arm in Myo1a mimicked the impact of actin-binding mutations.

122 iomyocytes with cMyBP-C antibody against the actin-binding N-terminal region reduced ADP sensitivity,

123 in nebulin, a giant muscle protein with 185 actin-binding nebulin repeats, are the major cause of ne

124 iomodin (Lmod) is a class of potent tandem-G-actin-binding nucleators in muscle cells.

125 al transduction mediated by certain tandem-G-actin-binding nucleators.

126 adhesion kinase) complex is essential for F-actin binding of ACF7.

127 conformation that makes them unavailable for actin binding or ATP hydrolysis, although a small fracti

128 Exon 16 of protein 4.1R encodes a spectrin/actin-binding peptide critical for erythrocyte membrane

129 Dematin's actin binding properties are regulated by phosphorylatio

130 nt functional impairment associated with its actin binding properties.

131 herin, beta-catenin, and the filamentous (F)-actin binding protein alphaE-catenin form a minimal cadh

132 Michael and colleagues (2016) show that the actin binding protein Coronin plays a critical role in a

133 Further, we show that the F-actin binding protein cortactin binds the PLS and is req

134 rylation of Y573 influences association of F-actin binding protein cortactin to MT1-MMP-positive endo

135 Furthermore, the actin binding protein ezrin relocated from the plasma me

136 assembly factors, we found that the small G-actin binding protein profilin directly inhibits Arp2/3

137 Synaptopodin, an actin binding protein that is important in maintaining p

138 P), the Rac GTPases MIG-2 and CED-10 and the actin binding protein UNC-115 (abLIM) are dedicated UNC-

139 Palladin is a key cytoskeletal actin binding protein whose normal function is to enable

140 chemical analysis revealed CORO1C, another F-actin binding protein, whose direct binding to PLS3 is d

141 This study reveals that actin-binding protein 1 (Abp1/HIP-55/SH3P7) is a negativ

142 tes WH2 domain functions with those of the F-actin-binding protein Abp1.

143 We recently found that the F-actin-binding protein afadin is required for lumen conti

144 Mutations in the ACTN4 gene, encoding the actin-binding protein alpha-actinin-4, are a rare cause

145 plasmic tail of classical cadherins to the F-actin-binding protein alpha-catenin.

146 Additionally, we found that PMD1 is an actin-binding protein and that a functioning actin cytos

147 Profilin 1 is a well studied actin-binding protein but how PFN1 mutations cause ALS i

148 The actin-binding protein calponin has been previously impli

149 We identify the endothelial actin-binding protein CD2-associated protein (CD2AP) as

150 is known to initiate changes to the cortical actin-binding protein cofilin to stimulate the depolymer

151 We have also defined in the actin-binding protein cofilin-1 a link between PP2A, act

152 osome transport in vivo also depend on the F-actin-binding protein cortactin.

153 anism linking a signaling intermediate to an actin-binding protein critical to T cell migration.

154 or binding to F-actin and represents a novel actin-binding protein domain.

155 resistant form of one of these proteins, the actin-binding protein elongation factor 1 alpha 1 (EF1al

156 polarized actomyosin network, and the Shroom actin-binding protein enhances myosin contractility loca

157 Vinculin is filamentous (F)-actin-binding protein enriched in integrin-based adhesio

158 29 differentially expressed spots, including actin-binding protein ezrin and its interaction partner,

159 The actin-binding protein Ezrin and the activator protein 1

160 Here, we report that the actin-binding protein filamin A (FlnA) physically intera

161 The actin-binding protein filamin A (FLNa) regulates neurona

162 ain (C-tail) also has a binding site for the actin-binding protein filamin A (FLNA); it is not known

163 own that villin, an epithelial cell-specific actin-binding protein functions as an anti-apoptotic pro

164 ving to modulate cell migration and named it actin-binding protein G (AbpG); this 971-amino acid (aa)

165 ied profilin 2 (Pfn2) mRNA, which encodes an actin-binding protein involved in endocytosis and neurot

166 Villin is a tissue-specific, actin-binding protein involved in the assembly and maint

167 a missense mutation in FLNA (Filamin A), an actin-binding protein located at Xq28, mutations in whic

168 The actin-binding protein nonmuscle tropomyosin (Tm) provide

169 uces the expression of the gene encoding the actin-binding protein profilin 1.

170 The actin-binding protein profilin-1 (Pfn1) inhibits tumor g

171 alpha-Catenin (alpha-cat) is an actin-binding protein required for cell-cell cohesion.

172 The role of synaptopodin (SP), an actin-binding protein residing in dendritic spines, in s

173 chemotactic responses, we identified a novel actin-binding protein serving to modulate cell migration

174 or ectopic apical constriction driven by the actin-binding protein Shroom and during embryonic wound

175 striction of ectoderm cells triggered by the actin-binding protein Shroom3.

176 Actin-binding protein sorting is critical for the self-o

177 Because Asef2 interacts with the F-actin-binding protein spinophilin, which localizes to sp

178 at alphaT-catenin is a constitutively active actin-binding protein that can physically couple the cad

179 Talin is a major actin-binding protein that controls both the inside-out

180 Leiomodin 2 (Lmod2) is an actin-binding protein that has been implicated in the re

181 ADD1 (adducin-1) is an actin-binding protein that has been shown to play import

182 Twinfilin 2a (Twf2a) is a small actin-binding protein that inhibits actin filament assem

183 PFN1 is a small actin-binding protein that promotes formin-based actin p

184 e identify AIM1 (absent in melanoma 1) as an actin-binding protein that suppresses pro-invasive prope

185 Vinculin is an actin-binding protein thought to reinforce cell-cell and

186 Filamin B (FlnB) is an actin-binding protein thought to transduce signals from

187 ing edge of the closing VBW that express the actin-binding protein transgelin (TAGLN) and TGFbeta rec

188 yotic cells express multiple isoforms of the actin-binding protein tropomyosin that help construct a

189 l change that exposes a cryptic site for the actin-binding protein vinculin.

190 Srv2/CAP is a conserved actin-binding protein with important roles in driving ce

191 Mutations in the actin-binding protein, alpha-actinin 4 (ACTN4), are link

192 Here we identify a Ca(2+)-sensitive actin-binding protein, alpha-actinin-4, as a novel group

193 s only 40 years ago that the first nonmuscle actin-binding protein, filamin, was identified and chara

194 Profilin1 (Pfn1), a ubiquitously expressed actin-binding protein, has an indispensable role in migr

195 LSP1, a F-actin-binding protein, is expressed in hematopoietic cel

196 Gelsolin, a multifunctional actin-binding protein, mediates cell death involving the

197 We find that the actin-binding protein, Moesin, is essential for NB proli

198 that filamin A (FLNA), a large cytoskeletal actin-binding protein, physically interacts with HIF-1al

199 The SRF target gene and actin-binding protein, vinculin, is sufficient to overco

200 Because vinculin (VCL) is an actin-binding protein, we asked whether it participates

201 Mammalian actin-binding protein-1 (mAbp1) is an adaptor protein th

202 g domains, is a novel ER membrane-associated actin-binding protein.

203 in increased levels of profilin1 (Pfn1), an actin-binding protein.

204 ated by phosphorylation of the transporters, actin binding proteins (radixin and myristoylated alanin

205 Importantly, the actin binding proteins Cyclase-Associated Protein and Ac

206 etitive and cooperative interactions between actin binding proteins help define their associations wi

207 the coordinated action of a large number of actin binding proteins that reorganize the actin cytoske

208 n cytoskeletal dynamics (e.g. RhoGTPases and actin binding proteins).

209 In mammalian oocytes, three actin binding proteins, Formin 2 (Fmn2), Spire, and prof

210 n-interacting proteins, actin filaments, and actin binding proteins, in a highly ordered and regulate

211 ing that its role, and perhaps that of other actin binding proteins, in growth cone motility is subst

212 Unusually for F-actin binding proteins, the DNGR-1 ligand binding domain

213 present in a complex with cofilin and other actin binding proteins.

214 fect(s) of Ca(2+)-sensitive and -insensitive actin-binding proteins (ABPs) on PC2(iv) channel functio

215 [PI(4,5)P2], regulate the activities of many actin-binding proteins (ABPs), including profilin, cofil

216 cellular processes at discrete locations by actin-binding proteins (ABPs), including the formins and

217 are connected to the actin cytoskeleton via actin-binding proteins (ABPs).

218 N-termini of SK2 channels interact with the actin-binding proteins alpha-actinin2 and filamin A, res

219 he band 3 macrocomplex, CD47 associates with actin-binding proteins and we confirm that CD47 membrane

220 Actin and actin-binding proteins are incorporated into HIV-1 parti

221 Many actin-binding proteins are thought to be stimulus-respon

222 These genes encode numerous actin-binding proteins as well as actin.

223 tion resulted in reduced Cdc12, F-actin, and actin-binding proteins at the CR, which in turn led to a

224 nical cues control the activities of various actin-binding proteins in different cellular, developmen

225 Conversely, how different sets of actin-binding proteins properly sort to distinct actin f

226 Filamins are a family of actin-binding proteins responsible for diverse biologica

227 Importantly, other actin-binding proteins such as fimbrin and espin show hi

228 Here, we demonstrate how the actin-binding proteins talin and vinculin cooperate to p

229 depolymerizing factors (ADFs) are a group of actin-binding proteins that contribute to reorganization

230 cortex is a thin layer of actin, myosin, and actin-binding proteins that subtends the membrane of ani

231 cient wound healing, but the contribution of actin-binding proteins to contraction of the extracellul

232 ipid bilayer coupled via membrane-associated actin-binding proteins to dynamic actin filaments and my

233 the cytoskeleton in IECs via changes in the actin-binding proteins VIL1 and GSN.

234 We studied the actin-binding proteins villin 1 (VIL1) and gelsolin (GSN

235 Subsequently many other nonmuscle actin-binding proteins were identified and characterized

236 Tropomyosins comprise a large family of actin-binding proteins with critical roles in diverse ac

237 esses and require the activities of multiple actin-binding proteins working in concert.

238 ngs to a plant-specific superfamily (NET) of actin-binding proteins, (2) VAP27, a plant homolog of th

239 t to an association between cytoskeletal and actin-binding proteins, a mesenchymal or hybrid EMT phen

240 l lines was upregulation of cytoskeletal and actin-binding proteins, a signature shared with mesenchy

241 ement in these processes is mediated by many actin-binding proteins, among which the cofilin family p

242 hemical and functional properties of diverse actin-binding proteins, both alone and in combination, h

243 ic events are choreographed by a plethora of actin-binding proteins, but the exact mechanisms are poo

244 We selected two vital Plasmodium berghei G-actin-binding proteins, C-CAP and profilin, in combinati

245 e filamins (FLNs), which are multifunctional actin-binding proteins, consist of 24 Ig domains.

246 which beta-III-spectrin, and likely similar actin-binding proteins, interact with actin, and how thi

247 Devoid of all known canonical actin-binding proteins, the prevalent parasite Giardia l

248 localization is specific to Fascin, as other actin-binding proteins, Villin and Profilin, do not exhi

249 ns that are specifically recognized by other actin-binding proteins.

250 oskeleton are controlled by a large array of actin-binding proteins.

251 the coordinated action of different sets of actin-binding proteins.

252 he calcium-regulated gelsolin superfamily of actin-binding proteins.

253 a region involved in the binding of several actin-binding proteins.

254 led by a vast array of intricately regulated actin-binding proteins.

255 cific member of the NETWORKED superfamily of actin-binding proteins.

256 ytoskeleton, via transmembrane integrins and actin-binding proteins.

257 cess, requiring the activity of more than 75 actin-binding proteins.

258 c autophosphorylation reactions within the F-actin binding region and permits F-actin remodeling by r

259 ith amino acid sequence corresponding to the actin binding region of eNOS residues 326-333 has been s

260 artially rescued by restoring the C-terminal actin-binding region of alpha-cat.

261 variant containing nine substitutions in the actin-binding region, which complements cdc3-124 cells.

262 from actin, thus allowing the association of actin-binding regions of FH2 to the barbed end.

263 changes in the spatiotemporal expression of actin binding/regulatory proteins.

264 One such protein is Xin-actin binding repeat containing 2 (XIRP2), an actin-cros

265 ons are located in the charged motifs of the actin-binding residues of tropomyosin 3, thus disrupting

266 The requirement for both membrane and F-actin binding reveals that myosin-mediated coupling betw

267 We now ask whether actin binding reverses this transition and if so, how th

268 demonstrate that, in addition to inhibiting actin binding, Ser-3 modification favors formation of a

269 e late endosomes likely through its PI3P and actin binding SH3YL1 Ysc84/Lsb4p Lsb3p plant FYVE (SYLF)

270 -binding domain, and mutants defective for F-actin binding show enhanced ability to retain YAP in the

271 A mutation, LK(47)/AA, within a predicted actin binding site (ABS) of F0 diminishes its interactio

272 ics and mutagenesis, we found that the EB1:F-actin binding site partially overlaps the well-character

273 etween the nucleotide binding pocket and the actin binding site.

274 ull cells, we show that while the C-terminal actin-binding site (ABS3) in talin is required for adhes

275 increased by vinculin and depends mainly on actin-binding site 2 (ABS2) within the middle of the rod

276 , a major cardiac isoform, has an N-terminal actin-binding site located within residues 43-90.

277 our data suggest that a second, low affinity actin-binding site may be universally used by ADF/cofili

278 t is part of the C-terminal tail domain, the actin-binding site of both isoforms.

279 We further find that a proposed actin-binding site within the missing connecting region

280 hat the anillin ActBD harbors three distinct actin-binding sites (ABS 1-3).

281 k growing filament barbed ends while three G-actin-binding sites (GABs) on other arms are available t

282 Tmods have alternating tropomyosin (TM)- and actin-binding sites (TMBS1, ABS1, TMBS2 and ABS2).

283 reas Tmods have alternating tropomyosin- and actin-binding sites (TMBS1, ABS1, TMBS2, ABS2), Lmods la

284 h, and comprise alternating tropomyosin- and actin-binding sites (TMBS1, ABS1, TMBS2, and ABS2).

285 s a 139-amino-acid protein containing five F-actin-binding sites and two G-actin-binding sites, and i

286 Mutations in Pfn1's actin-binding sites or reduction of Pfn1 eliminate the S

287 binds calmodulin and creates two coordinated actin-binding sites that constrain the actomyosin intera

288 taining five F-actin-binding sites and two G-actin-binding sites, and interacts with wheat (Triticum

289 ase gates a transition from weak to strong F-actin-binding states.

290 Tropomyosin (Tm) is an actin-binding, thin filament, two-stranded alpha-helical

291 We demonstrate that, upon G-actin binding, thymosin ss4 (Tss4), induces MRTF translo

292 In general, actin binding to ternary membranes prevented macroscopic

293 oligomerization and suggests that PIP2 and F-actin binding to vinculin are mutually permissive.

294 ed phosphate release, and the weak-to-strong actin-binding transition.

295 We show here that direct actin binding, via the inner centromere protein (INCENP)

296 nsion featuring a proline-rich domain and an actin-binding WASP-Homology 2 domain.

297 contain a C-terminal extension featuring an actin-binding WH2 domain.

298 nucleators, use tandem repeats of monomeric actin-binding WH2 domains to facilitate actin nucleation

299 cleator Cobl, despite having only a single G-actin-binding Wiskott-Aldrich syndrome protein Homology

300 sion containing a proline-rich domain and an actin-binding Wiskott-Aldrich syndrome protein homology