ライフサイエンスコーパス: actin-binding activity

1 the repeat domain maintains a significant F-actin binding activity.

2 dystrophin, utrophin, shared this rod domain actin binding activity.

3 tic activity, D33S (Asp --> Ser), had normal actin binding activity.

4 utant, K229A (Lys --> Ala), had intermediate actin binding activity.

5 f a GRE reporter while still maintaining its actin-binding activity.

6 ons on both protein aggregation and impaired actin-binding activity.

7 irst 20 amino acids of the latter exposes an actin-binding activity.

8 gment of villin that retains strong in vitro actin-binding activity.

9 CKS are necessary and sufficient to regulate actin-binding activity.

10 vailability of the PSD so as to activate its actin-binding activity.

11 (W59R and I149del) also showed an increased actin-binding activity.

12 found to contribute to the regulation of its actin-binding activity.

13 ins was previously shown to be necessary for actin-binding activity.

14 hat serine 175 of Amot was important for the actin-binding activity.

15 y mechanism dependent on both motor and tail actin-binding activity [1].

16 ked ACTN4 mutant, K255E, which has increased actin binding activity and is predominantly cytoplasmic,

17 This requires profilin's G-actin binding activity and its direct interaction with H

18 role of the first repeat of beta-spectrin in actin binding activity and of the second repeat in assoc

19 Biochemically, we characterize FRG1 actin binding activity and show that the cytoplasmic poo

20 l glomerulosclerosis) demonstrated increased actin binding activity and susceptibility of ACTN4 to ca

21 f human gelsolin domain 2 were assayed for F-actin binding activity and thermodynamic stability.

22 We show that myosin IIIB (MYO3B) lacks tail actin-binding activity and is unable to target COS7 cell

23 ins that requires both motor and tail domain actin-binding activity and show that the actin-binding t

24 outer membrane protein(s) with ATP-sensitive actin binding activity, and (2) a salt-inextractable, pr

25 eracts strongly with PPIs, and its monomeric actin-binding activity becomes regulated by PPIs.

26 A or truncation by mutagenesis eliminated F-actin binding activity but strongly enhanced actin depol

27 differences that account for their different actin-binding activities could not be determined.

28 iece have been purified and tested for their actin binding activity, cysteine reactivity, and thermal

29 with chimeric proteins demonstrate that the actin binding activity fully correlates with the ability

30 lear function of ACTN4 is independent of its actin binding activity in the cytoplasm.

31 artitioning of eEF-1A in Triton X-114 or its actin-binding activity in in vitro assays.

32 We have identified a novel actin-binding activity in the polyproline domain of both

33 The significance of CP's actin-binding activity in vivo was tested by determining

34 acterize a point mutant, H41F, which retains actin-binding activity, is more thermostable but, intere

35 E), or a protein fraction with ATP-sensitive actin-binding activity isolated from SE, to salt-washed

36 es not contain VI and VII regions, retains F-actin binding activity, its binding affinity for F-actin

37 S-transferase fusion proteins demonstrate an actin-binding activity mediated specifically by the kelc

38 The actin binding activities of the B subunits of V-ATPase r

39 These results suggest that EGF regulates the actin binding activity of ACTN4 by inducing tyrosyl-dire

40 of cortactin, which, in turn, changes the F-actin binding activity of cortactin.

41 ition, pp60(c-src) moderately inhibits the F-actin binding activity of cortactin.

42 utive spectrin-like repeats recapitulate the actin binding activity of full-length utrophin more fait

43 of gelsolin-LPS binding is inhibition of the actin binding activity of gelsolin as well as the actin

44 ver, overexpression of NtRac1 diminishes the actin binding activity of green fluorescent protein (GFP

45 lture cell caldesmon and tropomyosin (TM) on actin binding activity of human fascin.

46 It is thought that the F-actin binding activity of IQGAP1 is regulated by its rev

47 ts and actin filaments may contribute to the actin binding activity of other members of the actin cro

48 st for possible physiologic functions of the actin binding activity of V-ATPase, early responses of r

49 t the Hippo pathway negatively regulates the actin-binding activity of Amot family members through di

50 large multidomain proteins that regulate the actin-binding activity of capping protein (CP), a major

51 The interaction with PA inhibited the actin-binding activity of CP.

52 The actin-binding activity of fascin is down-regulated by ph

53 ses and the actin cytoskeleton, and that the actin-binding activity of IQGAP1 is regulated by calmodu

54 These substitutions eliminated the actin-binding activity of the B subunit fusion proteins.

55 The F-actin-binding activity of unacetylated Tpm1p is reduced

56 The actin-binding activity of vinculin is inhibited by an in

57 e results demonstrate that activation of the actin-binding activity of vinculin requires steps other

58 al third of dystrophin displayed no specific actin binding activity or competition with full-length d

59 > Ala), and R148A (Arg --> Ala), had minimal actin binding activity relative to wild type (wt) aldola

60 625-MDE exhibited actin-activated ATPase and actin-binding activities similar to wild-type MDE.

61 n-type headpiece domain natively devoid of F-actin binding activity, that of supervillin headpiece (S

62 lding of the N-terminal domain which confers actin-binding activity to villin-type headpiece domains,

63 issense mutations cause disease by impairing actin-binding activity, we engineered the K18N, L54R, D1