ライフサイエンスコーパス: acting

1 nd 3-halobenzyl groups furnished potent dual acting A1AR agonists and A3AR antagonists.

2 lyses focused on BH3 mimetics that are broad acting (ABT263 and obatoclax) or selective (ABT199, WEHI

3 en their spikelets were controlled by Ca(2+) acting across two nanodomains, one between plasma membra

4 sful drugs ever used in cancer chemotherapy, acting against a variety of cancer types.

5 One of the main immune cells acting against the virus are Natural Killer (NK) cells.

6 n could be specifically enhanced using trans-acting agents that counter the function of negative regu

7 No state acting alone can ward off health threats that span borde

8 esponse to systemic administration of a long-acting analog of the gut-hormone glucagon-like peptide-1

9 casei NFBC 338 transformed to express a long-acting analogue of GLP-1 or the isogenic control microbe

10 tensified treatment of midgut NETs with long-acting and repeatable octreotide, PRRT reduced the hazar

11 Long-acting anti-HIV products can substantively change the st

12 A paucity of novel acting antibacterials is in development to treat the ris

13 further evaluation of isoflurane as a rapid-acting antidepressant devoid of the psychotomimetic effe

14 cellular target for the development of fast-acting antidepressant drugs.

15 plicated in the mechanism of action of rapid-acting antidepressant ketamine: activation of brain-deri

16 elps resolve key discrepancies between rapid-acting antidepressants and local homeostatic mechanisms.

17 ponse biomarker for the development of rapid acting antidepressants.

18 C7A), in human PBMCs induces potent and long-acting antiretroviral response against several laborator

19 nd are being considered as partners for long-acting antiretrovirals for use in therapy or prevention

20 ach and capacity of the VA to deliver direct-acting antiviral (DAA) HCV therapy, supported by an infr

21 in subjects previously treated with a direct-acting antiviral (DAA) regimen.

22 BACKGROUND & AIMS: Interferon-free direct-acting antiviral (DAA) therapies are effective in patien

23 Although direct-acting antiviral (DAA) therapies for chronic hepatitis C

24 Direct-acting antiviral (DAA) therapy, recently approved for pa

25 virus-infected individuals receiving direct-acting antiviral (DAA) therapy.

26 cost-effectiveness of two alternative direct-acting antiviral (DAA) treatment policies in a real-life

27 otease inhibitor (PI; 2011-2013), and direct-acting antiviral (DAA; 2014-2015).

28 Resumption of direct-acting antiviral agent therapy after a temporary interru

29 ad not been treated previously with a direct-acting antiviral agent were assigned randomly to groups

30 n the renal transplant population but direct acting antiviral agents (DAA) provide an effective cure

31 er treatment with regimens containing direct-acting antiviral agents (DAAs) have limited retreatment

32 Current therapies with all-oral direct-acting antiviral agents are associated with high rates o

33 Survival data with direct-acting antiviral agents are not available.

34 Direct-acting antiviral agents have not been studied exclusivel

35 New direct-acting antiviral drugs for the treatment of chronic hepa

36 es have reported the effectiveness of direct-acting antiviral drugs in these patients.

37 ort-course combination therapies with direct-acting antiviral drugs that might be explored in future

38 ment) can affect the efficacy of this direct-acting antiviral regimen, and pretreatment resistance an

39 -daily, ribavirin-free, pangenotypic, direct-acting antiviral regimen, glecaprevir coformulated with

40 ospective observational cohort study, direct-acting antiviral therapy with SOF/ledipasvir, ombitasvir

41 ent of patients who previously failed direct-acting antiviral-based therapies with sofosbuvir-velpata

42 fficacy and safety of a once-daily, 2-direct-acting-antiviral-agent (2-DAA) combination of simeprevir

43 ained virological response (SVR) with direct-acting antivirals (DAA) is unclear.

44 titis C virus (HCV) patients involves direct-acting antivirals (DAA).

45 rld data on the effectiveness of oral direct-acting antivirals (DAAs) in predominantly minority HIV/H

46 with sustained virologic responses to direct-acting antivirals (DAAs), which lack immunomodulatory pr

47 rated data from recent trials of oral direct-acting antivirals (SOLAR 1 and 2), the United Network fo

48 ersus post-LT HCV treatment with oral direct-acting antivirals for patients with MELD scores between

49 reatment as Prevention (TasP) using directly-acting antivirals has been advocated for Hepatitis C Vir

50 Direct-acting antivirals produce high SVR rates in white, black

51 Despite acting as a barrier for the organs they encase, epitheli

52 lial cells and pericytes encase the surface, acting as a barrier that regulates transport of molecule

53 ligned PAA remained on the membrane support, acting as a beneficial barrier that prevented the acid-f

54 Consistent with Fic acting as a deAMPylation enzyme, its activity was both t

55 cantly alters the host response in the MLNs, acting as a decisive factor in infection outcome.

56 In normoxia, miR-574-3p, acting as a decoy, binds cytoplasmic hnRNP L and prevent

57 spital readmissions over time with mortality acting as a dependent terminal event.

58 urnover is controlled by the circadian clock acting as a dynamic homeostat responding to sucrose sign

59 Thus, by acting as a fine switch in the immune system, BiG emphas

60 specialization with alternative resource use acting as a fundamental agent driving divergence.

61 re we show how macromolecular force sensors, acting as a genome proxy, allow us to probe the pathways

62 express nitrous oxide reductase, potentially acting as a global sink for the greenhouse gas nitrous o

63 rs, with the Lewis acid component of the FLP acting as a hydride shuttle that enables alkyne 1,2-hydr

64 knockout mouse model of muscular dystrophy, acting as a link between alpha-DG and laminin(s).

65 enomic response to various stress signals by acting as a master transcriptional regulator.

66 sarcomeres and maintains muscle function by acting as a molecular chaperone.

67 hages, RECON antagonized STING activation by acting as a molecular sink for cdNs.

68 g a reversibly extendable region potentially acting as a molecular spring.

69 cts the rewarding effects of cannabinoids by acting as a negative allosteric modulator of alpha7 nico

70 on the effects of pyrazolo[4,3-c]quinolines acting as a new class of bacterial betaG-specific inhibi

71 s unusual regioselectivity in this reaction, acting as a nucleophile at the alpha-position to provide

72 e model also naturally explains how KaiA, by acting as a nucleotide exchange factor, can stimulate ph

73 and other vesicular trafficking processes by acting as a pair of molecular scissors for newly formed

74 ly of two hollow halves through a joint also acting as a partition.

75 t, two-domain multifunctional stress protein acting as a Phase II enzyme, activating cancer pro-drugs

76 by the greater proportion of stem and sheath acting as a physical barrier to bite formation.

77 e CH4 emissions for this region, potentially acting as a positive feedback to climate warming.

78 ated by all nuclear RNA polymerases, thereby acting as a positive modifier of global gene expression.

79 The FtsL helix is thus a candidate for acting as a potential mechanical connection to communica

80 ated by solvent 2,2,2-trifluoroethanol (TFE) acting as a proton shuttle.

81 ructure to promote processive DNA synthesis, acting as a sliding clamp for polymerases.

82 melanopsin is required for thermo-reception, acting as a thermo-opsin that ultimately feeds the local

83 nd gamma-amino-alpha,beta-unsaturated esters acting as a three-atom component to construct indoline u

84 c epithelial-mesencyhmal transition, thereby acting as a tumor suppressor.

85 rcles one DNA strand and excludes the other, acting as a wedge with an external DNA unwinding point d

86 Unlike all previously reported genes acting as activators of basal bud initiation, SPL4 acts

87 circadian disruption affects development by acting as an early life stressor, we examined birthweigh

88 roxo-diferric intermediate to be ambiphilic, acting as an electrophilic oxidant in the initial N-hydr

89 to maintain energy status during exercise by acting as an energy sensor for contracting muscle and st

90 compartmentalized inside droplets, each one acting as an isolated microreactor.

91 We propose a pathway that involves ERF74 acting as an on-off switch controlling an RbohD-dependen

92 Finally, by acting as an opsonin, GroEL-induced PTX3 promoted the as

93 to initiate testicular development, thereby acting as an upstream regulator of the male pathway in P

94 tly dependent upon blast exposure, with both acting as bridge symptoms to other postdeployment mental

95 ted by the expression of other miRNA targets acting as competing endogenous RNAs (ceRNAs).

96 Although endogenous RNAs acting as damage-associated molecular patterns (DAMPs) f

97 roles in oligodendrocyte differentiation by acting as dominant factors in the organization of myelin

98 inity and excellent KOP receptor selectivity acting as full or partial agonists, and one as an antago

99 suggesting a systemic supply of FKRP protein acting as glycosyltransferase.

100 posed System on-Glass hosts thin metal films acting as heating sources; hydrogenated amorphous silico

101 l regulator of lipid and glucose metabolism, acting as its transcriptional co-activator in endothelia

102 e immune responses with several TLR agonists acting as known B cell mitogens.

103 hoinositide 3-OH kinase alpha (PI3K-C2alpha) acting as limiting scaffold protein organizing clathrin

104 By acting as macrophage decoys, these nanoparticles bind an

105 Biochemically, Lmods differ from Tmods, acting as powerful nucleators of actin polymerization, n

106 one for connecting the WE and the other two acting as RE and AE.

107 te the activity of functional gene groups by acting as scaffolds that promote the local assembly of t

108 te photo(bio)electrochemical reactions while acting as sensitive biosensor for the detection of hydro

109 educed Cr species (either Cr(II) or Cr(III)) acting as spectators.

110 coupled formation of 3'-structural elements acting as terminators.

111 These results indicate that the somatopleure acting as the amniotic primordium also serves as a sourc

112 tance of fatty acids, in addition to sugars, acting as the form of fixed carbon transferred from the

113 gher for the black compared to the white RH, acting as the mediator between implicit prejudice and ma

114 Acting at a single metabotropic receptor subtype, ACh ex

115 Preclinical research shows that compounds acting at alpha7 nicotinic receptors (nAChRs) can reduce

116 tanding the role and regulation of nucleases acting at stalled forks with a focus on the nucleolytic

117 umulating evidence shows that in addition to acting at the cell membrane, AMPs may act on the cell wa

118 differentiation and nuclear reprogramming by acting at the cell surface.

119 ned uncontrolled despite treatment with long-acting beta-agonists and medium-to-high doses of inhaled

120 Salmeterol is a long-acting beta2-adrenergic receptor agonist used to treat c

121 with dual inhaled corticosteroid (ICS)/long-acting beta2-agonist (LABA) therapy in patients with chr

122 Inhaled corticosteroids and long-acting beta2-agonist combinations are more effective tha

123 copyrronium 110/50 mug with twice-daily long-acting beta2-agonist/inhaled corticosteroid salmeterol/f

124 tions) study, which compared once-daily long-acting beta2-agonist/long-acting muscarinic antagonist i

125 ravating environmental factors, use of short-acting beta2-agonists for rapid relief of symptoms, and

126 , including inhaled corticosteroids and long-acting beta2-agonists, is effective in patients for whom

127 urces; hydrogenated amorphous silicon diodes acting both as temperature sensors to monitor the temper

128 ct modulation of multiple pathway components acting both upstream and downstream of the mTOR kinase i

129 the efficacy of triple therapy with two long-acting bronchodilators and an inhaled corticosteroid in

130 Other controller medications, such as long-acting bronchodilators and biologics, may be required in

131 on the efficacy and safety of inhaled short-acting bronchodilators to treat asthma and wheeze exacer

132 ment, three intramuscular injections of long-acting cabotegravir 800 mg or saline placebo at 12 week

133 vents was higher in participants in the long-acting cabotegravir group (n=75 [80%]) than in those in

134 d-to-moderate injection-site reactions, long-acting cabotegravir was well tolerated with an acceptabl

135 wing upon perspectives from bilingualism and acting can help us understand the role of gesture in spo

136 We also identified cis- and trans-acting chromatin contacts to other genomic regions previ

137 The reduction in fast-acting cochlear compression associated with SNHL exagger

138 ly to risk in ASD cases who carry a strongly acting de novo variant.

139 t not those distal to the infection site, by acting directly on host cells.

140 The transcriptional network acting downstream of LIF, WNT and MAPK-ERK to stabilize

141 little is known about the molecular program acting downstream of Osr2 in the regulation of palatogen

142 derscore the need for effective peripherally acting drugs.

143 rane ballooning requires thrombin generation acting effectively in a positive feedback loop, mediatin

144 It can have a dual role, acting either as a mitogen or as a tumor suppressor.

145 compounds displayed a diversity of action by acting either on extracellular M. tb bacterial growth on

146 d that the first 22 bp of exon 3 contain cis-acting elements that enhance the exclusion of exon 3 to

147 s, including promoting accessibility of late-acting enhancers and decreasing accessibility of early-a

148 ancers and decreasing accessibility of early-acting enhancers.

149 biogenesis is partially dependent on a trans-acting factor FPA.

150 ries to provide a prediction of which trans -acting factors binding sites are disrupted/created and l

151 sis relies in large part on binding of trans-acting factors to cis-localized DNA sequence motifs.

152 Several potential estrogen-induced paracrine-acting factors were identified in the expression profile

153 Acting from the ASG and BAG sensory neurons, we show tha

154 ctosyl substitution and was shown to be endo-acting generating a more diverse mixture of oligosacchar

155 Liraglutide, a long-acting GLP-1 receptor agonist, is approved for treatment

156 Dual-acting glucagon-like peptide-1/glucagon receptor agonist

157 noglucosylation of N-glycans, and oppositely acting glucosidase II (GlucII), and that vIL-6 can promo

158 h-pre-patterns-growth" model, a persistently acting growth regulator whose distribution is pre-patter

159 Our comprehensive maps of cis-acting hippocampal meQTLs and eQTLs provide a link betwe

160 lating the abundance of the antagonistically acting hormones abscisic acid (ABA) and gibberellin (GA)

161 When acting in a complex visual environment, it is essential

162 gen signaling may reduce vocal plasticity by acting in a nonredundant and precise manner in the brain

163 nsin in the suppression of hundreds of loci, acting in both DNA methylation-dependent and methylation

164 novel proresolving role on macrophages when acting in concert with apoptotic PMN-expressed D6.

165 he dynamics of transcriptomes and epigenomes acting in concert with initial cell fate commitment rema

166 lation of DLG-1 protein is delayed by ZEN-4, acting in concert with its binding partner CYK-4/MgcRacG

167 SMC4, a core subunit of condensins I and II, acting in conjunction with CG methylation by MET1 (DNA M

168 ghly distributed tumor suppressive functions acting in diverse cellular contexts.

169 hile the stunting of fusion by deacylated HA acting in isolation may be balanced by other viral prote

170 he alpha 2A noradrenergic receptor (a2A-NAR) acting in prefrontal cortex.

171 Initially, with the support of the UPR acting in pro-survival mode, Enamp.S55I heterozygous mic

172 Opioid, serotonin and NMDA mechanisms acting in rostral ventromedial medulla promote analgesia

173 PC enrichment at the equatorial cortex, thus acting in tandem with MKlp2.

174 ion, there is no evidence for such selection acting in the case of resistance.

175 in complex linking key epigenetic regulators acting in the molecular control of embryonic bilateral s

176 an epigenetic repressor of gene expression, acting in the nucleus accumbens, a brain reward region,

177 enable us to uncover the most critical genes acting in the steps of cell fate determination and early

178 t codon selection is regulated by many trans-acting initiation factors as well as sequence/structural

179 Long-acting injectable antipsychotic medications were associa

180 Clozapine and long-acting injectable antipsychotic medications were the pha

181 antiretroviral drugs in development as long-acting injectable formulations.

182 Purpose The association between long-acting insulin analogs and increased breast cancer risk

183 also mediates the unfolded protein response acting intracellularly.

184 ts of the first phase 3 trial assessing long-acting intramuscular pasireotide in patients with Cushin

185 roteases that are abundantly available, fast-acting ligases are rare.

186 ained by the hydrophobic carbonaceous matrix acting like a filter favoring the release into water of

187 he DNA as well as the dissociation from DNA, acting like an anchor that restricts the dynamic mobilit

188 ght pipi* state, which affects the dynamics, acting mainly as a "doorway" state for the nOpi* state.

189 , TwTPS7v2 and TwTPS9v2, or the subsequently acting miltiradiene synthase, TwTPS27v2, led to decrease

190 ed once-daily long-acting beta2-agonist/long-acting muscarinic antagonist indacaterol/glycopyrronium

191 missense mutation, an unprecedented dominant-acting mutation of RPE65 identified in patients with aut

192 Moreover, a long-acting nanoformulation of compound I [compound I nanopar

193 ic antidepressant, imipramine, and a rapidly acting, non-monoamine-based antidepressant, ketamine, in

194 lex) to bind foreign DNA and recruit a trans-acting nuclease for target degradation.

195 ingle miRNA can control an entire process by acting on a crucial mediator; however, this is a quite e

196 s with a differential effect on the 2 sexes, acting on a genetic background.

197 lts illustrate a mechanism by which cocaine, acting on a key neuromodulation pathway, modifies the co

198 a more general framework, mechanical forces acting on a molecular system can strongly modify its rea

199 of CD mutations as a result of neutral drift acting on a small population of active hematopoietic ste

200 The external field is a magnetic field acting on a superparamagnetic microbead suspended in an

201 CLEASES (SDNs) initiate miRNA degradation by acting on AGO1-bound miRNAs to cause their 3' truncation

202 structural features, which identify enzymes acting on bulky substrates as a distinct subgroup of the

203 DA mediates opposing patterns of behavior by acting on different receptors within the same terminal r

204 onents is distinctive for its versatility in acting on diverse incompatible DNA end configurations co

205 A editing, catalyzed by Adenosine DeAminases acting on double-stranded RNA(dsRNA) (ADAR), occurs pred

206 IL-1beta, which inhibits B lymphopoiesis by acting on early lymphoid progenitors, S100A9 inhibits B

207 tion, whereas spatial evolutionary processes acting on edge subpopulations contributed less.

208 Bacteroides EstA, a sialate O-acetylesterase acting on glycosidically linked sialylate-O-acetylestera

209 spite abundant examples of natural selection acting on heritable traits, conclusive evidence for cont

210 s evolve by mutations and epigenetic changes acting on individuals in a population; tumors evolve by

211 I first consider the constraints and drivers acting on influenza A virus reassortment, including the

212 o uncover TRUB1 and PUS7 as the two key PUSs acting on mammalian mRNA and to computationally model th

213 the fetus, mediated by reproductive signals acting on metabolic organs.

214 nthesized in the periphery and in the brain, acting on multiple receptors to regulate gene transcript

215 genitors, S100A9 inhibits B lymphopoiesis by acting on myeloid cells and promoting the release of inf

216 hysiological responses in signalling modules acting on RLC phosphorylation and force responses, proba

217 the catalytic domain of Adenosine Deaminase Acting on RNA (ADAR2) that deaminates A to inosine (I) r

218 inase activity by ADAR2 (adenosine deaminase acting on RNA type 2) to transcripts in mammalian cells.

219 iepileptic activity can be mimicked by drugs acting on serotonin signalling pathways e.g. trazodone a

220 es in acidic conditions has been achieved by acting on the electronic character of the substituent at

221 Drugs acting on the endocannabinoid system and genetically mod

222 Prospectively, acting on the GABA-polarity switch offers a potential ta

223 voked responses, indicating that rather than acting on the nerves within the pancreas slice, CCK cell

224 in ontogenetic growth, rather than selection acting on the trait.

225 sibility to myc-epitopes we show that forces acting on the transmembrane segment produce loose cluste

226 tes effects of the neurotransmitter dopamine acting on these cells.

227 ntifying the first allosteric small molecule acting on these important therapeutic targets.

228 variation, as well as the natural selection acting on this variation that drives adaptation to envir

229 Copper, acting on unknown precursors, was associated with large

230 into the differential evolutionary pressures acting on virus subtypes, which can manifest into landsc

231 target mimics and lncRNAs that produce trans-acting or phased small-interfering RNA (tasiRNA/phasiRNA

232 glucogenic function, asprosin is a centrally acting orexigenic hormone that is a potential therapeuti

233 on between genetic and environmental factors acting over the life-course.

234 on between genetic and environmental factors acting over the life-course.

235 Ticagrelor is a direct-acting P2Y12 inhibitor and, unlike clopidogrel and prasu

236 igned (1:1:1) to receive treatment with long-acting pasireotide (60 mg intramuscularly every 28 days)

237 ed to assess the efficacy and safety of long-acting pasireotide and everolimus, administered alone or

238 vents with a suspected association with long-acting pasireotide monotherapy were gamma-glutamyltransf

239 INTERPRETATION: Long-acting pasireotide normalised mUFC concentration in abou

240 deaths were suspected to be related to long-acting pasireotide treatment.

241 We used isoproterenol, a rapidly acting peripheral beta-adrenergic agonist similar to adr

242 ce decreased with increasing adhesion-forces acting perpendicular to the surface, (3) nanoscopic disp

243 g interactions with the binding pocket, thus acting predominantly as a competitive antagonist that in

244 I has revealed negative feedback mechanisms, acting predominantly at the level of phytoene synthase-1

245 temporal evolution of GICs mass loss and the acting processes have remained unclear.

246 Here we harness the specificity and rapid-acting properties of bacteriophages as a potential proph

247 ular machinery consisting of dozens of trans-acting proteins.

248 This novel DNMT3B cis-acting QTL variant highlights the importance of genetica

249 These reports of direct-acting RAS inhibitors provide valuable insight for furth

250 portion with viral suppression for each long-acting regimen is not worse than the oral regimen propor

251 32 weeks following randomisation, both long-acting regimens met primary criteria for comparability i

252 _a gene which contains three overlapping cis-acting regulatory elements (GCN4, Skn1 and the RY-elemen

253 ic RNA (gRNA) requires the presence of a cis-acting RNA element called the 'packaging signal' (Psi).

254 fects, we evaluated the effects of a locally acting ROCK inhibitor (AMA0825) on intestinal fibrosis.

255 y: specific RNA molecules that contain a cis-acting sequence called the A2 response element (A2RE), h

256 we report the discovery of LX2761, a locally acting SGLT1 inhibitor that is highly potent in vitro an

257 ly conserved microRNA that targets the Trans-Acting Short Interference RNA3 (TAS3) transcript.

258 evolutionary changes in cis as well as trans acting signals have played a fundamental role in determi

259 we demonstrate that, in addition to locally acting signals, tissue-wide mechanical forces can act as

260 vides a means to extend the action of a long-acting, slow, effective release of antiretroviral therap

261 RGONAUTE7 results in the production of trans-acting small interference RNAs, which target mRNAs encod

262 omoting the biogenesis of TAS3-derived trans-acting small interfering RNA (ta-siRNA), which represses

263 Cis-acting SNPs of hippocampal meQTLs and eQTLs significantl

264 2.2 and the hydrotropism-specific MIZ1, both acting specifically in elongation zone cortical cells.

265 ve colonization factor PrpB by the two trans-acting sRNAs RcoF1/2.

266 modestly augmented by the addition of a long-acting ss-agonist.

267 onstrate the versatility of these STARs-from acting synergistically with existing constitutive and in

268 otential and limitations of B. bacteriovorus acting therapeutically against K. pneumoniae in serum, i

269 PI3Kdelta was functionally critical in Treg, acting there to control T-cell receptor signaling, cell

270 tabilized by biophysical feedback mechanisms acting through pore characteristics and microbial access

271 radiation, and CPR-4 seems to exert RIBEs by acting through the insulin-like growth factor receptor D

272 that promotes the integrity of the Z ring by acting through ZapB and raises the possibility of the ex

273 into demographic and environmental processes acting throughout the annual cycle.

274 immunomodulator in lung cancer progression, acting to drive immune escape via a C3/C5-dependent path

275 in a second shell away from the FAD cofactor acting to polarize the peptide bond through interaction

276 Here, we review another checkpoint acting to potentiate the activity of innate immune cells

277 ments provided evidence of natural selection acting to prevent the plastic response in PTDH3 activity

278 as specific roles in cardiovascular tissues, acting to regulate cardiac metabolism and contractile fu

279 inase complex consists of several components acting together to cleave viral DNA into unit length gen

280 onstrate that our approach can uncover trans-acting transcriptional control circuits that affect co-r

281 ia, the regulation of gene expression by cis-acting transcriptional riboswitches located in the 5'-un

282 While trans-acting tRNA editing proteins have been found to countera

283 bjective methods for partitioning the forces acting underneath the stance foot.

284 esting environmental and dietary factors are acting upon a preexisting genetic background.

285 When acting upon an object, we need to represent its visual f

286 ive inheritance, while those linked to trans-acting variants are most often dominantly inherited.

287 ion factor binding differences linked to cis-acting variants generally exhibit additive inheritance,

288 normalized by spinal delivery of duloxetine acting via 5-hydroxytryptamine type 2A receptors and tem

289 Here, we show that nuclear calcium acting via a target gene, VEGFD, is required for hippoca

290 uptor with mixed agonist/antagonist activity acting via endogenous estrogen receptors.

291 0(-10)), suggesting that pathogenic variants acting via expression level are less likely to involve M

292 iments demonstrate how environmental signals acting via FOS/JUN and BAF coordinate with cell-type-spe

293 therapeutic potential of gut-derived signals acting via nonphysiologic mechanisms.

294 This work suggests that MPH, acting via noradrenergic mechanisms, can substantially a

295 gle nucleotide polymorphisms (SNPs) possibly acting via obesity-related traits, hsCRP, based on 16 SN

296 l activity of histone deacetylase inhibitors acting via p53 activation.

297 iatal medium spiny neurons but that dopamine acting via PKA inactivates ARPP-16 leading to selective

298 se vascular niche is controlled by PPARgamma acting within APCs.

299 To determine the role of ROCK2 acting within CD4(+) cells in allergic airways responses

300 his was accomplished by isolating the forces acting within each foot segment through controlling the