ライフサイエンスコーパス: actinomycete

1 lite are dispersed in separate regions in an Actinomycete.

2 of this facultative intracellular pathogenic actinomycete.

3 n in Actinomadura kijaniata, a soil-dwelling actinomycete.

4 s coelicolor, the model antibiotic-producing actinomycete.

5 s as well as other natural product-producing actinomycetes.

6 orthologs being present in at least 10 other Actinomycetes.

7 roduced by Mycobacterium smegmatis and other actinomycetes.

8 in Mycobacterium tuberculosis and many other actinomycetes.

9 ng clinically significant species of aerobic actinomycetes.

10 ) and is the predominant thiol found in most actinomycetes.

11 r recognized species, and 22 as unidentified actinomycetes.

12 nown members of this family are found in the actinomycetes.

13 Ins) and is the major thiol produced by most actinomycetes.

14 f the alpha- and beta-Proteobacteria and the Actinomycetes.

15 n of organic Ags, most commonly thermophilic actinomycetes.

16 cer Saccharopolyspora erythraea and in other actinomycetes.

17 l strain improvement of antibiotic-producing actinomycetes.

18 bacteria, 93 nocardiae, and 30 other aerobic actinomycetes.

19 olates of all clinically significant aerobic actinomycetes.

20 ally significant species and taxa of aerobic actinomycetes.

21 n identified as a major thiol in a number of actinomycetes.

22 ivating enzymes from a diverse collection of actinomycetes.

23 odification strategy in antibiotic-producing actinomycetes.

24 e is known about RLA in antibiotic-producing actinomycetes.

25 he major low molecular weight (LMW) thiol in Actinomycetes.

26 mycothiol, the low molecular weight thiol of actinomycetes.

27 phosphorylation of GlgE is widespread among actinomycetes.

28 rganisms considered to belong to the aerobic actinomycetes.

29 the regulation of developmental processes in Actinomycetes.

30 le of labeling trehalose glycolipids in live actinomycetes.

31 the role of BldD is conserved in sporulating actinomycetes.

32 erse bacteria ranging from proteobacteria to actinomycetes.

33 occur exclusively in morphologically complex actinomycetes.

34 ction of distant ssgB orthologues from other actinomycetes.

35 is functionally conserved in all sporulating actinomycetes.

36 can hinder the introduction of DNA into many actinomycetes; (2) self-replicating plasmid-cloning vect

37 The antibiotic kijanimicin produced by the actinomycete Actinomadura kijaniata has a broad spectrum

38 another subset of DHQS-like proteins in the actinomycete Actinosynnema mirum and the myxobacterium S

39 The actinomycetes, although not all the Actinobacteria, are

40 revious co-culture screen, we found that one actinomycete, Amycolatopsis sp. AA4, inhibited aerial hy

41 ry metabolite isolated from a marine-derived actinomycete and displays inhibitory activity against TN

42 of apoptotic protein domains was detected in Actinomycetes and Cyanobacteria, which suggests a major

43 Mycothiol is the major thiol present in most actinomycetes and is produced from the pseudodisaccharid

44 Mycothiol is a novel thiol produced only by actinomycetes and is the major low molecular weight thio

45 Mycothiol is a novel thiol produced only by actinomycetes and is the major low-molecular-weight thio

46 e analysis of polyketide synthases (PKSs) in actinomycetes and other Gram-positive bacteria.

47 s are important natural products produced by Actinomycetes and other organisms via the polymerization

48 GSH was absent in all actinomycetes and some of the other gram-positive bacter

49 IRs are the longest reported thus far for an actinomycete, and are proposed to represent the chromoso

50 ontuberculous mycobacteria, 4 (0.3%) aerobic actinomycetes, and 2 (0.2%) isolates from theM. tubercul

51 rculous mycobacteria, 145 (11%) were aerobic actinomycetes, and 98 (7%) wereMycobacterium tuberculosi

52 clusters for the synthesis of antibiotics in actinomycetes, and also for the synthesis of antibiotics

53 been purified from eucaryotes, gram-positive actinomycetes, and archaea.

54 CofE is found in archaea, the aerobic actinomycetes, and cyanobacteria.

55 ry proteins, some of which are found only in actinomycetes, and is elicited by both extracellular and

56 Fungi, actinomycetes, and Plasmodium spp. also synthesize PABA

57 xamination of six cultures ruled out aerobic actinomycetes, and they were omitted from the study.

58 amino acid sequence similarity with several actinomycete antibiotic export proteins.

59 ome, not available in most eubacteria except Actinomycetes, appears to contribute to Mtb's resistance

60 Actinomycetes are a group of gram-positive bacteria that

61 Cultivated bacteria such as actinomycetes are a highly useful source of biomedically

62 Marine actinomycetes are a prolific but underexploited source f

63 lly rich genus further documents that marine actinomycetes are a significant resource for drug discov

64 Actinomycetes are apparently unique among bacteria in th

65 Actinomycetes are excellent sources for novel bioactive

66 that type I methanotrophs, methylotrophs and actinomycetes are important organisms involved in using

67 Actinomycetes are increasingly recognized as pathogenic

68 WhiB-like proteins of actinomycetes are known to co-ordinate iron-sulfur (Fe-S

69 y metabolites that have been discovered from actinomycetes are often in the form of biosynthetic hybr

70 o improve secondary-metabolite production in actinomycetes are potentially numerous, but have been li

71 While soil-dwelling actinomycetes are renowned for secreting natural product

72 Although actinomycete bacteria are one of the primary sources of

73 -aromatic polyketide biosynthesis within the Actinomycete bacteria that is responsible for the format

74 ptidases have only been found in animals and actinomycete bacteria.

75 nd in the majority of cellulolytic fungi and actinomycete bacteria.

76 multicellular differentiation in sporulating actinomycete bacteria.

77 ith their hosts include fungi, oomycetes and actinomycete bacteria.

78 nic amino acid 3,5-dihydroxyphenylglycine in actinomycetes bacteria responsible for the production of

79 biotic and spore pigment biosynthesis in the actinomycetes bacteria.

80 CHY1 resembles actinomycete (bacterial) chymotrypsins (family S2) rathe

81 bably arose by lateral gene transfer from an actinomycete bacterium.

82 vely processed for the cultivation of marine actinomycetes belonging to the genus Salinispora.

83 tion factors that are present throughout the actinomycetes but absent from other organisms.

84 equencing to identify members of the aerobic actinomycetes, but the study also shows that a high degr

85 ry metabolism and, sometimes, sporulation in actinomycetes by binding to specific receptor proteins,

86 8 Mycobacterium species and 11 other aerobic actinomycetes by the presence or absence of BstEII recog

87 s has been made on antibiotic discovery from actinomycetes by using high-throughput fermentation, iso

88 Glycosylation is unusual among actinomycete carotenoids, and sioxanthin joins a rare gr

89 Conversely, actinomycete chymotrypsins are much more closely related

90 (PRA) for routine identification of aerobic actinomycete clinical isolates were evaluated for 299 cu

91 homologues (all from members of the aerobic actinomycetes) coded for proteins homologous over the en

92 mportance of c-di-GMP-dependent signaling in actinomycete colony morphology and development and ident

93 ate that MSH production is restricted to the actinomycetes, could have significant implications for t

94 d solid medium for mycobacterial and aerobic actinomycetes culture and demonstrates that solid medium

95 analysis of 21,494 mycobacterial and aerobic actinomycetes cultures performed over 10 months to deter

96 mycetes) and new sources (for example, other actinomycetes, cyanobacteria and uncultured bacteria).

97 Kutznerides are actinomycete-derived antifungal nonribosomal hexadepsipe

98 Kutznerides, actinomycete-derived cyclic depsipetides, consist of six

99 and highly efficient synthesis of the marine actinomycete-derived natural product saliniketal B.

100 Mycobacteria and other actinomycetes do not produce glutathione but make mycoth

101 Among other aerobic actinomycetes, each group most closely resembled the ass

102 ch would help explain why sphIR unlike other actinomycete ENase genes seemed to be expressed in E. co

103 e detection and treatment of infections with actinomycetes, especially those caused by mycobacteria.

104 MSH was found at significant levels in most actinomycetes examined.

105 ncoded by Rv2672 is conserved exclusively in actinomycetes, exhibits both lipase and protease activit

106 ods have demonstrated that indigenous marine actinomycetes exist in the oceans and are widely distrib

107 olymerase-binding protein that occurs in the actinomycete family of bacteria and is regulated by the

108 terium tuberculosis and other members of the actinomycete family produce mycothiol (MSH or acetylcyst

109 m tuberculosis and many other members of the Actinomycetes family produce mycothiol, i.e., 1-d-myo-in

110 y Mycobacterium tuberculosis, members of the Actinomycetes family, to maintain an intracellular reduc

111 the saline culture of a new group of marine actinomycetes, for which we have proposed the name "Mari

112 Progress has been made to isolate novel actinomycetes from samples collected at different marine

113 The ggh-A ORF has features typical of an actinomycete gene including high GC content (70.5%) and

114 WhiB-like proteins exclusive to the GC-rich actinomycete genera play significant roles in pathogenes

115 gas vesicle gene clusters in members of the actinomycete genera Streptomyces, Frankia and Rhodococcu

116 hat display the codon preferences typical of actinomycete genes.

117 robe for new RIF-associated genes in several actinomycete genomes, we identified a heretofore unknown

118 icolor that is well represented in sequenced actinomycete genomes.

119 Members of the marine actinomycete genus Salinispora constitutively produce a

120 e data derived from 75 strains of the marine actinomycete genus Salinispora for pathways associated w

121 The marine actinomycete genus Salinispora maintains extraordinary l

122 three closely related species of the marine actinomycete genus Salinispora reveals extraordinary bio

123 zed the genomes of 119 strains of the marine actinomycete genus Salinispora, which is currently compr

124 Members of the actinomycete genus Streptomyces are non-motile, filament

125 Two related actinomycetes, Glycomyces sp. strain NRRL B-16210 and St

126 longing to the genus Corynebacterium and the actinomycete group of organisms.

127 ologous protein expression in members of the actinomycete group, including codon usage, post-translat

128 Recent screening of marine actinomycetes has led to the discovery of a new lineage

129 The soil actinomycetes have been important sources of antibiotics

130 n (see scheme), produced by a marine-derived actinomycete in saline culture, shows significant activi

131 combined with milleri group streptococci and actinomycetes in 33% and 26% of cases, respectively.

132 gical manipulation of organisms (principally actinomycetes) in which complex polyketides have thus fa

133 y characterized Nocardiopsis, a soil-derived actinomycete, in stationary phase.

134 , S. oralis, and S. sanguis, as well as oral actinomycetes, including A. viscosus, A. odontolyticus,

135 was conserved across mycobacteria and other actinomycetes, including an AT-rich sequence that was li

136 Most actinomycetes, including Mycobacterium tuberculosis, do

137 ative regulators of the sigma factor SigB in actinomycetes, including pathogens like Mycobacterium tu

138 The genomes of many actinomycetes, including the soil dwelling bacterium Str

139 ion and morphological differentiation during actinomycete interactions.

140 ut the roles of these molecules in mediating actinomycete interactions.

141 The tip growth of filamentary actinomycetes is investigated within the framework of la

142 sulfur proteins found exclusively within the actinomycetes, is required for the late stages of sporul

143 Screens for environmental actinomycete isolates carrying frontalamide-like biosynt

144 Amplicons from all aerobic actinomycete isolates lacked BstEII recognition sites, t

145 , we detected the pepM gene in ~5% of random actinomycete isolates.

146 ardia species isolates, and 61 other aerobic actinomycetes isolates under routine clinical laboratory

147 etabolite identification studies in multiple actinomycetes, it has been proposed that cholesterol sid

148 angucycline-type antibiotics produced by the actinomycete, Kibdelosporangium sp. MJ126-NF4, contain a

149 of antifungal natural products from the soil actinomycete Kutzneria sp. 744 contain two sets of chlor

150 icin is a potent lantibiotic produced by the actinomycete Microbispora corallina and contains unique

151 tent type I lantibiotic produced by the rare actinomycete Microbispora corallina that is in preclinic

152 g macrolide antibiotic mycinamicin II in the actinomycete Micromonospora griseorubida.

153 ether putative gas vesicle proteins in these actinomycetes might actually be involved in flotation or

154 elium development and stress response in the actinomycetes, might be under the regulation of as yet u

155 throughput fermentation, isolation of marine actinomycetes, mining genomes for cryptic pathways, and

156 and sensitive GC measurements, that the soil actinomycete Mycobacterium smegmatis mc(2)155 constituti

157 re we show that an obligate aerobe, the soil actinomycete Mycobacterium smegmatis, adopts an anaerobe

158 It is circular, like those of the pathogenic actinomycetes Mycobacterium tuberculosis and Corynebacte

159 Microbiology showed actinomycetes (n = 7) and mixed bacteria (n = 9).

160 xides (epoxyalkanes) by the alkene-utilizing actinomycete Nocardia corallina B276 was investigated.

161 clic beta-lactam antibiotics produced by the actinomycete Nocardia uniformis subsp. tsuyamanensis ATC

162 s a monocyclic beta-lactam isolated from the actinomycete Nocardia uniformis that shows moderate anti

163 s a monocyclic beta-lactam isolated from the actinomycete Nocardia uniformis, which shows moderate ac

164 Recent fermentation studies have identified actinomycetes of the marine-dwelling genus Salinispora a

165 ns, DpgA-D, required for the biosynthesis by actinomycetes of the nonproteinogenic amino acid monomer

166 r the control of the sigmaR homologue in the actinomycete pathogen Mycobacterium tuberculosis.

167 that the sigmaR system also functions in the actinomycete pathogen Mycobacterium tuberculosis.

168 modified peptide lantibiotic produced by the actinomycete Planomonospora alba.

169 ndous diversity and novelty among the marine actinomycetes present in marine environments.

170 These marine actinomycetes produce different types of new secondary m

171 Oral actinomycetes produce fructosyltransferase (FTF) enzymes

172 The highly aerobic actinomycetes produce mycothiol, a conjugate of N-acetyl

173 at Amycolatopsis sp. AA4, a so-called "rare" actinomycete, produces a novel siderophore, amychelin, w

174 Gordonia species are aerobic actinomycetes recently recognized as causing human disea

175 Ergothioneine, also produced by actinomycetes, remains a mystery despite many years of s

176 Molecular typing of the actinomycete Rhodococcus equi is insufficiently develope

177 etabolism of acetone was investigated in the actinomycete Rhodococcus rhodochrous (formerly Nocardia

178 mparative studies of the propylene-oxidizing actinomycete Rhodococcus rhodochrous strain B276 showed

179 In contrast to another Actinomycete, Rhodococcus erythropolis, Mtb's beta-chain

180 se biosynthetic gene cluster from the marine actinomycete Saccharomonospora sp. CNQ-490 and produced

181 bly line polyketide synthase produced by the actinomycete Saccharopolyspora erythraea that synthesize

182 th of several strains of the obligate marine actinomycete Salinispora arenicola has led to the identi

183 nd B are unusual polyketides from the marine actinomycete Salinispora arenicola that inhibit ornithin

184 metabolites produced by the obligate marine actinomycete Salinispora tropica (strain CNB-392), the p

185 hydrogenase/reductase enzyme from the marine actinomycete Salinispora tropica that is involved in the

186 el cyanosporasides C-F (3-6) from the marine actinomycetes Salinispora pacifica CNS-143 and Streptomy

187 of characterized cytochrome P450 enzymes in actinomycete secondary metabolic pathways are strictly s

188 It is thought that soil microbes, likely actinomycetes, serve as the main global sink for troposp

189 species, Nocardia species, and other aerobic actinomycetes) showed 100% specificity and sensitivity.

190 ganic compound produced by a wide variety of Actinomycete soil organisms, myxobacteria, and cyanobact

191 Streptomyces and other bacterial actinomycete species produce many important natural prod

192 he primary vegetative sigma factors in other actinomycete species.

193 thologs of VlmL were identified in two other actinomycetes species that also contain orthologs of the

194 yrolactone signalling system, members of the actinomycete-specific Wbl class of regulatory proteins a

195 Cultivation of actinomycete strain CNQ-418, retrieved from a deep ocean

196 olated from the saline culture of the marine actinomycete, strain CNQ-140, identified as a member of

197 t unlike the linear chromosomes of the model actinomycete Streptomyces coelicolor A3(2) and the close

198 e non-pathogenic, non-glycopeptide-producing actinomycete Streptomyces coelicolor carries a cluster o

199 Concomitant expression of these genes in the actinomycete Streptomyces coelicolor produced epothilone

200 s biosynthesis in the genome-minimized model actinomycete Streptomyces coelicolor provided the 57.6 k

201 one of 18 cytochrome P450 (CYP) genes in the actinomycete Streptomyces coelicolor, ordered active sit

202 yotes and in one of the Ku homologs from the Actinomycete Streptomyces coelicolor.

203 The actinomycete Streptomyces scabies 87-22 is the causal ag

204 ces coelicolor, with a similar role in other actinomycetes such as Mycobacterium tuberculosis.

205 The regulation of disulphide stress in actinomycetes such as Streptomyces coelicolor is known t

206 Actinomycetes, such as Mycobacterium species, are Gram-p

207 f [4Fe-4S]-containing proteins found only in actinomycetes, such as Streptomyces and Mycobacteria.

208 t proteasome core in Mycobacteria and allied actinomycetes suggested that additional elements of this

209 ose of related ('erm-type') genes from other actinomycetes suggests that the combined presence of tlr

210 evertheless, Streptomyces hygroscopicus, the actinomycete that produces GdA, has evolved an Hsp90 fam

211 n of organic Ags, most commonly thermophilic actinomycetes that cause farmer's lung disease.

212 millimolar levels by mycobacteria and other actinomycetes that do not make glutathione.

213 many of these genes is almost certainly the actinomycetes that make the antibiotics and therefore ne

214 istic association with filamentous bacteria (actinomycetes) that produce antibiotics that suppress th

215 ight thiol, unique to mycobacteria and other actinomycetes, that performs a role analogous to glutath

216 Unlike proteasomes isolated from other Actinomycetes, the open-gate Mtb mutant 750 kDa particle

217 toxification enzymes are novel and unique to actinomycetes, thereby representing potential antimycoba

218 llular cellulases in the cellulose-degrading actinomycete Thermobifida fusca is controlled by a trans

219 ecently sequenced genome of the thermophilic actinomycete Thermobifida fusca revealed an orphan nonri

220 In addition, the level of the major actinomycete thiol buffer, mycothiol, was fourfold lower

221 ding an overview of the physiology of a soil actinomycete, this study presents insights on the transc

222 abolizing ACADs in M. tuberculosis and other actinomycetes through bioinformatic analysis.

223 athway appears to be negatively regulated in actinomycetes through the phosphorylation of GlgE by Pkn

224 scovopsis on the one hand and the ant-fungus-actinomycete tripartite mutualism on the other.

225 cultivation-resistant, poorly characterized actinomycete, Tropheryma whippelii.

226 roducts and biological diversity, and marine actinomycetes turn out to be important contributors.

227 enera (totaling 43 species) of other aerobic actinomycetes using both the MALDI-TOF MS manufacturer's

228 al interactions within a set of 20 sequenced actinomycetes were carried out.

229 Actinomycetes were the most quantitatively important mic

230 RbpA), encoded by Rv2050, is specific to the actinomycetes, where it is highly conserved.

231 tive intracellular, Gram-positive, soilborne actinomycete which can cause severe pyogranulomatous pne

232 orneol (2-MIB) produced by cyanobacteria and actinomycetes, which are the major sources for "earthy"

233 ycan present in Mycobacterium spp. and other actinomycetes, which constitutes a major component of th

234 t small molecular weight thiol found only in actinomycetes, which include mycobacteria.

235 Phylogenetically related rifampin-resistant actinomycetes with mutations mapping to clinically domin