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1 )-HETE) production, indicating an inhibitory action of I3MO on 12/15-LO and consequently on STAT3.
2 and addition of 1.2mM EGTA did not alter the action of harmane on [(3)H]5-HT release from rat brain c
3 -resolved structural characterization of the action of cellulases on a nano-flat cellulose preparatio
4 pproaches require blockade of the inhibitory action of cocaine on a diverse array of monoamine transp
5 vative was unexpectedly obtained through the action of Fe(2+) on a dynamic library of imines generate
6 reveals the underlying heterogeneity of the action of GroES/EL on a bound polypeptide substrate, whi
7 constrained DNA to investigate the annealing action of HARP on a physiologically relevant substrate.
9 n addition, we report a kinetic study of the action of trypsin on a peptide having more than one clea
12 ch elucidating the mechanisms underlying the actions of nutritional supplementation on AD is necessar
13 hese results indicated an important modifier action of Nedd9 on ADPKD pathogenesis involving failure
14 inhibitor and an anti-oxidant normalized the action of insulin on Akt and eNOS activation in the ging
17 on AR antagonism and that the dual targeting action of ES on AR and GR can be further translated to P
21 horylation is required for the physiological action of SynIII on axon specification and neurite outgr
23 e studies was to elucidate the mechanisms of action of MPA on B cells isolated from healthy individua
26 des in bacteria, we investigated whether the action of polyphenols on bacteria could be due in part t
27 s far as we know, this is the first time the actions of AMPs, on bacterial membranes and on model mem
29 dentified neuronal circuits that mediate the action of these hormones on behavior and peripheral tiss
30 within the entire NAc affects the rewarding actions of cocaine on behavior (six to eight mice per gr
36 we determined their respective roles in the actions of estrogens on body composition and glucose hom
37 Hence, this study identifies a dual mode of action of SSRIs on bone remodeling and suggests a therap
39 phic, and could be explained by differential actions of SST on both GABAergic and glutamatergic curre
40 in the RvT pathway, reversed the protective actions of these statins on both joint and systemic infl
41 s stimulation has the capacity to modify the actions of morphine on brainstem noradrenergic nuclei, w
43 ts indicate a suppressing and a facilitating action of Cplx3/4 on Ca(2+)-dependent tonic and evoked n
46 he dual host-protective and tumour sculpting actions of immunity on cancer and establishing the basis
47 e-channel level, MBED mimicked the agonistic action of caffeine on cardiac RyR gating (i.e., stabiliz
49 ly by activated CD4 T cells, and that direct action of IL-21 on CD8 T cells was critical for the VV-s
50 ng evidence supports the hypothesis that the actions of proinflammatory mediators on cells harboring
54 as essential intermediates for the synaptic action of IL-1beta on central glutamatergic synapses.
58 ABCG8 S107X mutation does not influence the action of dietary PS on circulating cholesterol concentr
59 reduces sodium currents and antagonizes the action of BTX on cockroach sodium channels, suggesting t
60 Human red cell differentiation requires the action of erythropoietin on committed progenitor cells.
61 nt experiments were designed to characterize actions of dopamine on complex EPSCs in slices of rat br
62 uch as catechol and its derivatives from the action of colonic microbiota on cranberry polyphenols.
64 e purpose of this study was to determine the actions of LXA4 on cultured human conjunctival goblet ce
67 nally, we formulated a kinetic model for the action of Zn(2+) on DAT that emulated all current experi
68 es from the sugar-phosphate backbone and the action of DNA glycosylases on deaminated, oxidized, and
70 se findings may shed light on the preventive actions of A. paronychioides on diabetic glucotoxicity.
73 equivalently, nor contribute equally to the action of topo IV on different types of DNA substrates.
77 re likewise detected in vivo and reflect the action of FGF signaling on downstream targets during bon
79 brightness encoding studies, we examined the action of D-serine on each intensity used and then appli
80 the question of what mechanism underlies the action of cortactin on ENaC activity, we assayed the eff
81 To further determine the mechanism of the action of insulin on ENaC, we used mouse mpkCCDc14 princ
83 ly kinase inhibitor PP2, indicating that the action of pilocarpine on endogenous M3R is biased toward
84 lamp studies have shown that the suppressive actions of insulin on endogenous glucose production (EGP
85 uting stents may be due to the non-selective actions of antimitogenic drugs on endothelial cells, lea
86 ass B, type I (SR-BI), which is important to actions of HDL on endothelium and other processes, requi
87 ormonal and nutritional cues and mediate CNS actions of insulin on energy balance and peripheral meta
89 ng whole cell voltage clamp methodology, the actions of dexmedetomidine on excitatory glutamatergic a
90 s physiological features of the facilitatory action of dopamine on fast-spiking interneurons to asses
95 s a bright red synthetic dye produced by the action of bromine on fluorescein and stains basic protei
96 With these results, an updated model for the action of MinC on FtsZ is proposed: MinC interacts with
98 r blockade with AM251 (10 mum) prevented the action of CCK on GABA release both from CCK+ basket cell
100 After yohimbine plus cue reinstatement, the actions of CRF-R2 on GABA and glutamate release were rev
102 g that inhibition of Ievoked results from an action of Li(+) on Galpha, probably through inhibition o
105 t blocking AChRs with alpha-BTX reversed the action of neural cells on GDNF secretion by skeletal mus
107 ion within 30 min is consistent with a rapid action of glucocorticoids on GLP-1 bioavailability, resu
108 ave shown inconsistent results regarding the actions of antidepressants on glucocorticoid receptor (G
109 ental excitatory-to-inhibitory switch in the actions of GABA on glutamatergic neurons in neocortical
110 evidence for the existence of an inhibitory action of Gi3 on Gs that is under the control of the D2S
111 that such patterns may reflect the indirect action of selection on GS, through a multiplicity of phe
112 hese data point to species-specific modes of action of BDE-99 on h/mNPC development into the oligoden
115 re we compare and contrast the mechanisms of actions of Rg3 on hERG1 with three other members of the
118 ical and molecular mechanisms underlying the action of KIS on hippocampal synaptic plasticity in mice
119 onical Wnt/beta-catenin pathway (CWP) in the action of ISO on HPC expansion and comparison of ISO wit
120 e elucidate the mechanism of the non-genomic action of progesterone on human spermatozoa by identifyi
122 Fstl3 overexpression blocked the inhibitory action of activin A on hypertrophy and Smad2 activation.
124 es, ablation of DIP2A reduced the protective actions of FSTL1 on hypoxia/reoxygenation-induced apopto
125 detected herein may form the basis of direct action of CsA on IL-22 expression by T cells, which may
126 a putative metabolite of 2-AG, can mimic the actions of 2-AG on IL-2 regulation through PPARgamma act
129 evolutionary outcomes, and the deterministic action of selection on individual mutations, which favou
130 ed the role of BK channels in modulating the action of ethanol on inhibitory synaptic transmission me
131 y prepared mouse brain slices to examine the actions of KOR on inhibitory transmission in the BNST.
132 al and biophysical mechanisms underlying the actions of PA on insulin-activated mTOR/p70 S6Kinase sig
134 t experimental studies tested the protective action of estrogens on ischemic stroke using acute treat
135 d Claspin, it plays an important role in the action of ATR on its critical downstream target Chk1.
137 vage site specificity as well as the ordered action of prothrombinase on its compound substrate is re
138 se, and as a consequence this influences the action of the nucleotide on its downstream biological ta
139 cid (ZOL) in order to enhance the inhibitory action of this miRNA on its canonical targets such as No
142 hese enhancements were not due to the direct actions of TLR ligands on LCs, but mainly dependent on T
143 ion of Ac2-26 revealed the anti-inflammatory actions of Ac2-26 on leukocyte infiltration and on the r
144 the preoptic region blunted the stimulatory action of exogenous leptin on LH secretion and prevented
146 es have provided physiological mechanisms of action of niacin on lipid metabolism and atherosclerosis
147 rstanding of the physiological mechanisms of action of niacin on lipid metabolism and atherosclerosis
148 study sheds light into the as yet unrevealed action of PFOS on lipid mediators in affecting testicula
149 the concept that a combined hepatic specific action of PGC-1beta on lipid synthesis and secretion, as
150 states of GH resistance results from direct actions of GH on lipid uptake and de novo lipogenesis, w
152 way in the hippocampus is obligatory for the action of cannabinoids on LTP and spatial memory formati
153 hese findings define a new mechanism for the action of IL-1beta on LTP and point to a potential thera
154 e present study unveils a novel mechanism of action of neferine on lung cancer cells in the induction
157 s thought to depend critically on the direct action of IFN-gamma on macrophages, this premise has nev
160 ction did not reverse the ligand-independent action of the TR on many gene targets and did not fully
161 These data provide support for the direct action of GABA on mechanisms of acetylcholine release in
162 nimal actin cortex to directly visualize the action of individual myofilaments on membrane-bound acti
163 , it is necessary to understand the critical actions of alcohol on membrane proteins that regulate fu
164 s critical for the proliferative/profibrotic action of TGF-beta on mesenchymal cells, and yet it is n
165 suppression of the innate immune cells, the action of safinamide on microglia/macrophages was compar
166 and prevents the inhibitory and destructive actions of nitric oxide on mitochondrial oxidative metab
168 ing aids our understanding on the modulatory action of harmane on monoamine levels and could potentia
169 h receptor(s) mediate the stemness promoting actions of IGF-II on mouse subventricular zone neural pr
172 rast with studies suggesting that the direct action of inflammatory cytokines on muscle is sufficient
173 tivation and results from a newly identified action of the compound on mutant Ryr1 to reduce Ca(2+) l
174 ties of IL-4 can be attributed to the direct action of this cytokine on myeloid effector cells, depen
177 ubunit selectivity, we examined the blocking action of Cu(2+) on neurons of the mouse cerebellum and
179 We sought to investigate the mechanism of action of lynx1 on nicotinic receptor function, through
181 own to modulate nociception, but the site of action of MC4R signaling on nociception remains to be el
185 mechanism with retinoic acid to control the action of retinoic acid on ocular targets during postnat
190 To identify the molecular mechanisms of action of SrRan on osteoblasts, we investigated its effe
194 ta) mouse model and present evidence for the action of sex hormones on pancreatic beta-cell function
204 rter assays; and antagonized the prosurvival action of BAFF on primary mouse B cells in vitro A singl
205 This phenotype can be attributed to a direct action of galectin-8 on primary cultures of osteoblasts
207 by S-S bonds is required for the inhibitory action of S1b on prolactin-induced LF-mediated function
208 olyl-isomerization, thus indicating that the action of Pin1 on PSD-95 is critical for this effect.
209 y significantly contribute to the disruptive actions of these drugs on pubertal maturation and the de
210 ese results can be explained by the observed actions of 5-HT on RA projection neurons, and both effec
214 se findings provide a plausible mechanism of action of propranolol on regression of infantile hemangi
216 ing a sulfur atom), blocked the vasodilatory action of H2O2 on resistance vessels and resulted in hyp
220 CV) infusions, we examine the dose-dependent actions of CRF on sensory-evoked discharges of neurons i
221 To assess the possibility that this new action of Syt-7 on SG recruitment may involve calmodulin
226 athways, and this can dramatically alter the actions of these compounds on specific brain circuits im
227 n together, our results demonstrate that the action of retinoid signaling on spermatogonial different
229 heoretical model, we quantitatively cast the action of depletants on supercoiled bacterial DNA as an
233 Herein we report the formation of H2S by the action of NO on synthetic [2Fe-2S] clusters when the rea
235 reuptake inhibitors (SSRIs) would impact the action of 5-HT on thalamic axon responses to netrin-1 in
236 Whereas only 5HT(7) mediated the inhibitory action of 5HT on the release of proinflammatory cytokine
238 regation are able to prevent the deleterious action of Abeta on the excitatory/inhibitory equilibrium
240 , and resistance of acetylated starch to the action of amyloglucosidase on the degree of substitution
242 onstrated that Lcn2 is required for the full action of ATRA on the induction of UCP1 and PGC-1alpha e
245 hypothalamic projection, suggesting a direct action of cannabinoids on the retinohypothalamic tract w
247 and migration correlated with an inhibitory action of cortistatin on the neointimal formation in 2 m
248 zation is mediated by SLO3, we evaluated the action of cSrc inhibitors on the heterologously expresse
249 (Ishikawa) cells to determine the estrogenic action of D3 on the activation and nuclear translocation
251 ment of the GroEL apical domains to exert an action of forceful unfolding on the nonnative polypeptid
253 trongly demonstrated the specific inhibitory action of GnIH on the adenylate cyclase/cAMP/protein kin
256 hesis that divergent mechanisms underlie the action of inhibitory steroids on the rho 1 GABA receptor
257 istortion and index modulation caused by the action of light on the azo-dopant; upon photo-excitation
260 n channel activation rather than by a direct action of phosphorylation on the capsaicin binding site.
262 ncomplete understanding of the mechanisms of action of specific drugs on the atrial substrate at diff
267 erivative, 4-methylpyridine; and akin to the actions of 4-AP on the structurally unrelated Kv channel
268 proportion is increased via the stimulatory actions of ERRgamma on the expression of miR-499 and miR
270 rgo gyrification, indicating region-specific actions of FGF2 on the VZ and subventricular zone (SVZ).
271 exin messenger RNA in female rats was due to actions of glucocorticoid receptors on the orexin promot
272 -binding protein/p300 reduced the inhibitory actions of IFN-gamma on the Abca1 promoter, suggesting t
277 pportunity to shed light on the mechanism of action of anesthetics on these important ion channels.
280 and repair, but the underlying mechanisms of action of hypercapnic acidosis on this pathway is unclea
282 ndence and lung cancer; however, the mode of action of nicotine on this receptor subtype has been inc
283 ession, indicating that the ligand-dependent actions of PR on this gene may involve additional indire
284 ed to evoke dopamine release, and inhibitory actions of quinpirole on this release were examined.
287 important mediator of Treg suppression, the action of IL-10 on Tregs themselves is less well charact
289 "passenger" mutation) by T(E) cells requires action of IFNgamma on tumor stroma cells to avoid select
293 lso used isolated hepatocytes to examine the action of various oxypurines on ureagenesis and to asses
295 cepts have also emerged on lipid-independent actions of niacin on vascular endothelial oxidative and
296 usside (10 mumol l(-1) , n = 8) mimicked the action of CCh on VFT, an effect that was also blocked by
298 an virome, is regulated by the counterpoised actions of multiple cytokines on viral promoters that ha
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