ライフサイエンスコーパス: activated form

1 ding affinity when compared with the caspase-activated form.

2 an occupy multiple conformations even in the activated form.

3 c model structure of full-length MotB in its activated form.

4 sistent with existing scattering data for an activated form.

5 on or its switch from an inactive form to an activated form.

6 thrombin mediated secondary cleavage) of the activated form.

7 proteins to analyze the structures of their activated forms.

8 ed between the red (dark) and far red (light-activated) forms.

9 er a monosaccharide employing its nucleotide-activated form, acting as a Leloir glycosyltransferase.

10 in p65-NFkappaB protein were in reduced and activated forms after hypoxia, thereby being blocked by

11 arge Stokes shifts in both pre-activated and activated forms, allowing simultaneous use with common d

12 In addition, expression of both p53 and its activated form as well as the expression of p53 target g

13 reversibly binds growth factors and, in its activated form, binds to low density lipoprotein recepto

14 olecular models of truncated PLCbeta2 in its activated form complexed with Gbetagamma and in the cata

15 suggesting that inhibitors selective for the activated form could provide a high therapeutic index.

16 e created by ligating NH2-terminal truncated activated forms (Delta) to the estrogen receptor (ER) ho

17 transformation of the zymogenic FXIII to its activated form especially in the context of FXIIIA and F

18 res that LC3 effectively redistributes in an activated form from nucleus to cytoplasm, where it plays

19 e wild-type form are receptor dependent, the activated form (Go-GTP) can signal when the receptor is

20 s AMP, to the phosphorylated, constitutively activated form, "GPa." However, activation of GP in this

21 tures of legumain in the zymogenic and fully activated form in complex with different substrate analo

22 P (10 muM) increased the expression of CD11b activated form in eosinophils from healthy, but not asth

23 re, recent data show that Hsp90 exists in an activated form in malignant cells but in a latent inacti

24 are constitutively present in lipid rafts in activated forms in HTLV-1-infected T cells that express

25 the N-terminal region characteristic of the activated form is absent.

26 roughout the neuron, but its phosphorylated, activated form is highly enriched in the axon.

27 hibitor 4-(tert-butyl)phenylacetylene, whose activated form is known to attach to the distal-pocket T

28 cells into the uridine 5'-diphosphate (UDP)-activated form, it was not incorporated into GAGs.

29 n-like processing of Sde2 into a short-lived activated form may function as a checkpoint to ensure pr

30 UDP-xylose is the nucleotide-activated form necessary for incorporation of xylose int

31 ely facilitates interaction with the agonist-activated form of a G-protein-coupled receptor (R*) and

32 Conversely, expression of an activated form of Akt in purified Schwann cells increase

33 Finally, we show that, when an activated form of Akt is delivered into LNCaP cells by e

34 ng antibodies recognizing the phosphorylated/activated form of AKT kinases, we observed elevated phos

35 nsgenic mice expressing a membrane-targeted, activated form of Akt under control of the 2',3'-cyclic

36 Th17 cells expressing a constitutively activated form of AKT were resistant to PI3Kdelta inhibi

37 ells ectopically expressing a constitutively activated form of Akt3 or endogenously expressing mutant

38 gs complexed within the CD91/LRP ligand, the activated form of alpha2-macroglobulin (alpha2M*).

39 the HIV-1 envelope protein gp120 bound to an activated form of alpha4beta7.

40 precursor cells, we conditionally express an activated form of an FGF receptor or delete the FGF rece

41 compound failed to significantly suppress an activated form of another RTK, the Drosophila epidermal

42 Moreover, the co-expression of Cat-1 and an activated form of Arf6 in fibroblasts was sufficient to

43 Studies in Drosophila have revealed that an activated form of Armadillo, the effector of Wnt signall

44 ic mouse line that expresses a conditionally activated form of ATF6 in the heart.

45 c-restricted expression of a novel tamoxifen-activated form of ATF6, ATF6-MER.

46 e model that expresses a novel conditionally activated form of ATF6.

47 Whereas the activated form of ATM and H2AX-gamma foci were rarely ob

48 In converse, conditional expression of an activated form of beta-Catenin leads to expansion of Nkx

49 Expression of this activated form of beta-catenin led to the formation of l

50 encoding either a stabilized, constitutively activated form of beta-catenin or a dominant negative fo

51 Ectopic expression of an activated form of beta-catenin or Wnt14 in early differe

52 gene transfer to force the expression of an activated form of beta-catenin that should constitutivel

53 mportance, we have targeted expression of an activated form of beta-catenin to the urothelium of tran

54 with those measured by enzyme assay for the activated form of biotin-p38alpha.

55 Misexpression of an activated form of BMPR1b in the gizzard upregulates Sox9

56 Experiments using a constitutively activated form of c-Abl, small interfering RNA against c

57 to constitutively express high levels of the activated form of c-jun N-terminal kinase (JNK), a membe

58 Expression of an activated form of calcineurin in one set of astrocyte cu

59 tion, whereas expression of a constitutively activated form of CaMKII mimicked the effects of morphin

60 nogenic soft agar assay and detection of the activated form of caspase-3 and cleavage of poly(ADP-rib

61 Our studies suggest the calpain-activated form of caspase-7 has unique enzymatic activit

62 genesis of C431 resulted in a constitutively activated form of CBS that could not be further activate

63 Cat-1 from NIH3T3 fibroblasts expressing an activated form of Cdc42 (Cdc42 F28L), or from the human

64 sed an assay in yeast where expression of an activated form of Cdc42, a Rho-type guanosine triphospha

65 We demonstrate that CRL4(CDT2) targets the activated form of CHK1 for destruction in the nucleoplas

66 The activated form of Claspin contains two repeated phosphop

67 nesis and lipolysis, forced expression of an activated form of CREBH protein in the liver significant

68 resolution structure of the proteolytically activated form of Cry5B.

69 uorescein, fluorescein and resorufin with an activated form of cyclic trimetaphosphate to give interm

70 clease-coupled DNA methylation assay with an activated form of Dnmt1 engineered to lack the replicati

71 ratin 14 promoter to target expression of an activated form of Edar in transgenic mice, we show that

72 tudies, the effects of a novel conditionally activated form of EGF-R, v-ErbB:ER, on the morphological

73 s overexpression enhances the activity of an activated form of EGFR.

74 somal maturation assay and observed that the activated form of EhRab35 significantly increased the ra

75 xide synthase (r(part) = 0.46, P = 0.02), an activated form of endothelial nitric oxide synthase.

76 gested that evaluation of the phosphorylated/activated form of ErbB-2 might be more precise in defini

77 ng translocated in liposarcoma (TLS)-ERG, an activated form of ERG found in human leukemia.

78 esults from cytoplasmic sequestration of the activated form of ERK by PEA15.

79 Mutant tibiae have increased levels of the activated form of ERK1/2, consistent with the idea that

80 cent virions preferentially incorporated the activated form of ERK2 (pERK2) into the tegument.

81 y, FHL2 interacted more efficiently with the activated form of ERK2 than with the dephosphorylated fo

82 Induction of an activated form of FoxM1 was sufficient to increase beta-

83 The activated form of FVIII, FVIIIa, functions as a cofactor

84 ed receptor kinases (GRKs) phosphorylate the activated form of G protein-coupled receptors leading to

85 ounced with the mutationally or functionally activated form of Galpha(13) compared to that of wild-ty

86 Here we determine that the activated form of Galpha(s) binds tubulin with a K(D) of

87 Axin preferentially binds the activated form of Galpha12, a behavior consistent with o

88 ounced with the mutationally or functionally activated form of Galpha13 as compared with the wild-typ

89 proteins that specifically interact with the activated form of Galphaz.

90 Conversely, expression of a constitutively activated form of GSK3beta sensitized cancer cells to mT

91 e report that expression of a constitutively activated form of HIF2alpha (P405A, P530A, and N851A, na

92 of inhibitors shows higher affinity for the activated form of Hsp90 compared to our earlier 8-sulfan

93 To test our system, we synthesized the activated form of human mitogen-activated ERK activating

94 The activated form of hypoxia-inducible factor enhances Notc

95 We investigated whether mice that express an activated form of IKKbeta in the esophageal epithelia de

96 uced platelet aggregation, expression of the activated form of integrin alphaIIbbeta3, and exposure o

97 ells engineered to express human SERT and an activated form of integrin beta3 exhibited enhanced SERT

98 the structural features associated with the activated form of Itk, we have solved the NMR structure

99 SH2-Bbeta binds to the activated form of JAK2 and various receptor tyrosine kin

100 An activated form of JAK2, unable to bind Lnk, caused great

101 Expression of the activated form of Janus kinase 1 supported a role for IL

102 duced phosphorylation of JunD at Ser-100, an activated form of JunD.

103 umors that developed in mice that express an activated form of Kras (Kras(LSL-G12D/+);Ptf1a(Cre/+) mi

104 Expression of an activated form of KRAS (KrasG12D) in pancreata of mice i

105 m with LSL-KRAS(G12D) mice, which express an activated form of KRAS and develop spontaneous pancreati

106 2H/+);Pdx-1-Cre (KPC) mice, which express an activated form of Kras in pancreatic tissues, develop pa

107 rved following overexpression of Pitx2 or an activated form of Lef1, suggesting an effect on cell pro

108 Importantly, we show that this activated form of LRRK2 is substantially enriched at the

109 ferentially interact with the phosphorylated/activated form of MAD, and Nup93 acts to recruit the imp

110 defects due to loss of Msk are rescued by an activated form of MAPK or the secreted epidermal growth

111 MKP3 dephosphorylates the activated form of MAPK, inhibiting the RAS/MAPK arm of t

112 xpressed dominant-negative or constitutively activated form of MEK5 to inhibit or activate the MEK5-E

113 lls with CP-654577 reduces the levels of the activated form of mitogen-activated protein kinase, incr

114 lpha/beta activity, and the expression of an activated form of MKK6 (an immediate upstream activator

115 ction in myogenic processes, we expressed an activated form of mouse calcineurin A in Drosophila and

116 yzed hydroacylation between aldehydes and an activated form of N=N bond was achieved under mild condi

117 The ligand CTFs compete with an activated form of Notch for cleavage by gamma-secretase

118 Interestingly, the expression of an activated form of Notch-1 rescued some, but not all, the

119 d by inducing expression of a constitutively activated form of Notch.

120 -inducible manner, the ectopically expressed activated form of Notch1 (ICN1) displayed oncogene-like

121 l of Notch1 in solid tumors, we expressed an activated form of Notch1 (N1ICD) in the developing mouse

122 Activated form of Notch1 promotes xenograft tumor growth

123 Expression of the activated form of Notch1 restores AKT activity and enabl

124 :nicd1a transgenic embryos overexpressing an activated form of notch1, nicd1a, displayed increased cp

125 n this study, we show that the effects of an activated form of Notch2 (N2IC) on the T-cell lineage ar

126 Although expression of a constitutive activated form of Notch3 (ICN3) results in the induction

127 conclude that there is no accumulation of an activated form of O2 before C-H abstraction in the Dbeta

128 nability to correctly position Asp168 in the activated form of p38alpha.

129 or the transport of antimonite [Sb(III)], an activated form of Pentostam or Glucantime.

130 Subsequent studies demonstrated that an activated form of PI 3-kinase restored Rac GTP loading i

131 , but not HIV infection alone, contained the activated form of PKR, which localized predominantly to

132 dy specific for the tyrosine-phosphorylated, activated form of PLCgamma1, we now show that chronic mo

133 ing SKN-1, the MEDs, PAL-1, and the Wnt/MAPK-activated form of POP-1, are responsible for activating

134 cretion by strains containing a mutationally activated form of prfA, the key regulator of L. monocyto

135 t that hES cells localize a conformationally activated form of proapoptotic BAX to the trans Golgi ne

136 on of 3'-phosphoinositol lipids (PI3Ps), the activated form of Rac, a small GTPase, and F-actin.

137 We investigated whether expression of the activated form of Ras in gastric chief cells of mice lea

138 ream of HER2 by increasing the half-life the activated form of Ras.

139 Furthermore, TORC2 binds specifically to the activated form of RasC.

140 This reaction is catalyzed by an activated form of RecA, acting as a co-protease to stimu

141 oes not inhibit SRE reporter induction by an activated form of Rho kinase.

142 rescue phenotype, suggesting that it is the activated form of Rho1 that binds Gbetagamma.

143 This phenotype can be recapitulated using an activated form of RhoA and rescued by inhibiting Rho-kin

144 al regeneration or the decay of Meta II, the activated form of rhodopsin.

145 solid tumors, we established a conditionally activated form of ROCK II by fusing the kinase domain to

146 Mero-S100A4) that reports on the Ca2+-bound, activated form of S100A4.

147 luble guanylyl cyclase (sGC) itself, the NO -activated form of sGC, and phosphodiesterase(s) (PDE).

148 re known mutations predicted to result in an activated form of Shp2, whereas six are new mutations.

149 In this study, the biosynthesis of this activated form of sialic acid completely from endogenous

150 lial and idiopathic PAH are deficient in the activated form of Smad1.

151 We have found that expression of an activated form of Smo by stem cells of the hair-follicle

152 ngly inhibited BCC-like tumors induced by an activated form of Smoothened.

153 decreased its interaction with the receptor-activated form of SmSmad2, in vitro.

154 entify regions of the chromosome at which an activated form of Spo0A binds in vivo.

155 Expression of an activated form of Src relocated the KDEL receptor (KDEL-

156 -Tyr containing proteins, an antibody to the activated form of Src-family PTKs was used to localize a

157 othelial cell-specific overexpression of the activated form of SREBP2 synergized with hyperlipidemia

158 Stat3 protein levels and the levels of the activated form of Stat3 (pStat3) at P12, P15, P18, and P

159 Conversely, expressing a constitutively activated form of STAT3 (STAT3-C) in Smad4-intact cells

160 pression were increased by overexpressing an activated form of Stat3 but decreased by attenuation of

161 , while the introduction of a constitutively activated form of Stat3 into immortalized human breast e

162 ereas the overexpression of a constitutively activated form of STAT3 promoted HSC senescence through

163 igodendrocytes; (2) the overexpression of an activated form of STAT5 prevents alpha-amino-3-hydroxy-5

164 Transgenic mice expressing a constitutively activated form of STAT5b have been shown previously to c

165 A constitutively activated form of STAT6 is able to bypass IL-4 upstream

166 n addition, we demonstrate expression of the activated form of STAT6, a mediator of IL-4 signaling, b

167 inal vinculin head domain in complex with an activated form of talin.

168 the embryo and antagonizes the ability of an activated form of Tar/Acvr1b to induce endoderm at the a

169 C-893 selectively killed cells expressing an activated form of the anabolic oncogene Ras in vitro and

170 gulated by the polarized distribution of the activated form of the Cdc42 protein, rather than by the

171 Transgenic mice expressing a constitutively activated form of the cellular homologue Akt2 specifical

172 ate that albicin specifically recognizes the activated form of the complex, allowing more efficient i

173 neered to inducibly express a constitutively activated form of the cyclic AMP-dependent protein kinas

174 Conversely, expressing a constitutively activated form of the Drosophila JAK kinase (hop(Tum-l))

175 The presence of the activated form of the effector caspase (caspase-3) was o

176 is required to stabilize the lifetime of the activated form of the enzyme against reoxidation of Fe(H

177 ss spectrometry data show that the TIH-bound activated form of the enzyme closely resembles the inhib

178 )(III) couple), the kinetic stability of the activated form of the enzyme has been greatly diminished

179 An activated form of the enzyme is apparent on large genomi

180 hat while the thermodynamic stability of the activated form of the enzyme is unchanged (characterized

181 In the activated form of the enzyme, the MoaD C terminus is pre

182 ther occurs prior to catalysis to produce an activated form of the enzyme.

183 MVP also interacts with the activated form of the extracellular-regulated kinases (E

184 ) to the Golgi complex is initiated when the activated form of the GTPase Sar1p recruits the Sec23p-S

185 ted cells is rescued by the expression of an activated form of the immediate upstream p38-activating

186 d levels of expression of fibronectin and an activated form of the integrin alphavbeta3, which coordi

187 Here, we describe a mouse line expressing an activated form of the K-Cl cotransporter Slc12a4 (Kcc1),

188 ctive form of human rhodopsin bound to a pre-activated form of the mouse visual arrestin, determined

189 ne to enforce expression of a constitutively activated form of the Notch 4 receptor, we show that sig

190 wo known clock components [Lfng mRNA and the activated form of the Notch receptor (cleaved Notch intr

191 ory progenitors, we transiently expressed an activated form of the Notch1 receptor (NICD) using a com

192 The activated form of the Notch1 receptor, which promotes th

193 Cells expressing the activated form of the Notch4 receptor (ICD4) were resist

194 Recruitment of the Src kinase to the activated form of the platelet-derived growth factor (PD

195 inant antibody (scFvSCE5), which targets the activated form of the platelet-integrin glycoprotein IIb

196 s a crucial factor for stabilizing the light activated form of the protein, and have been used to pro

197 oiled coil of the plug, thus stabilising the activated form of the protein.

198 es not detectably affect wild-type Ras or an activated form of the Ras-related Rho GTPase.

199 he intracellular domain of Notch, a dominant activated form of the receptor, is sufficient to prevent

200 An activated form of the response regulator CheY destabiliz

201 steady-state level of the phosphorylated or activated form of the response regulator CheY dictates t

202 tory element-binding protein (SREBP)-1c, the activated form of the transcription factor.

203 unt of PKMzeta protein and the amount of the activated form of this kinase, phospho-PKMzeta (p-PKMzet

204 UDP-D-galacturonate, the activated form of this sugar, is known to be formed by t

205 trast to bacteria where dTDP-rhamnose is the activated form of this sugar.

206 isplay substantially increased levels of the activated form of transforming growth factor beta, a pot

207 We then localized the activated form of TrkB to a discrete population of cells

208 Furthermore, selective expression of an activated form of UNC-43 in ADF neurons is sufficient to

209 nic mice that overexpressed a constitutively activated form of YAP (YAP(S127A)), and measured protein

210 Using a constitutively activated form of Yen1, we show that uncontrolled Yen1 a

211 ed as key reagents for the origin of life as activated forms of acetate analogous to acetyl-CoA.

212 characterized by combined overexpression of activated forms of AKT and neuroblastoma Ras viral oncog

213 the TGF-beta signaling pathway by expressing activated forms of ALK-1 and ALK-5, type I receptors for

214 in-proteolysis similar to that observed with activated forms of alphaT*.

215 phila Arfaptin protein directly binds to the activated forms of Arf6 and Rac1 GTPases, and mutants in

216 sponse, characterized by the accumulation of activated forms of ATM and Chk2 as well as nuclear foci

217 in, inhibited wild-type B-Raf kinase but not activated forms of B-Raf.

218 etroviral transduction of the constitutively activated forms of both GTPases into primary murine macr

219 d in mice through the combined expression of activated forms of both KRas and Akt in glial progenitor

220 (RCAS)/TVA system to transfer genes encoding activated forms of BRAF, KRas, Akt and Cre to nestin-exp

221 ion has attracted considerable interest, and activated forms of BRAF, such as BRAF(V600E), have becom

222 hich is specific for a neoantigen exposed in activated forms of C3.

223 The activated forms of calcineurin or the calcineurin-depend

224 o the cytoplasm and the nucleus, whereas the activated forms of calpain-7 and -10 are found only in t

225 Using antisera specific for the activated forms of caspases, the family of cysteine prot

226 However, unlike many GEFs, Cool-2 binds to activated forms of Cdc42 and Rac.

227 Da protein that formed a stable complex with activated forms of Cdc42 and thereby showed characterist

228 three-dimensional structures of the apo and activated forms of DtxR show conformational changes in t

229 ther contexts, and MsEphrin colocalizes with activated forms of endogenous Src in the leading process

230 etastases of uveal melanoma patients express activated forms of ERBB2 (the coreceptor for ERBB3) and

231 In this study, we ask: Are activated forms of ERK, RSK, and CREB colocalized in the

232 partate receptor subunit NR2B as well as the activated forms of extracellular signal-regulated kinase

233 Here, we show that wildtype and mutant activated forms of FGFR3 increase expression of the cyto

234 veral multiple myeloma cell lines expressing activated forms of FGFR3, NDGA generally resulted in a d

235 efects are associated with low levels of the activated forms of focal adhesion kinase (FAK) and extra

236 alian cells that these RhoGEFs interact with activated forms of G alpha 12 or G alpha 13 through thei

237 Interestingly, expression of the activated forms of Galpha12 or Galpha13 in the PC3 and D

238 Instead, expression of the activated forms of Galpha12 or Galpha13 in these cell li

239 Coexpression of the activated forms of Galphai1, Galphai2, and Galphai3, but

240 he global gene expression pattern induced by activated forms of H-Ras, RhoA, Rac1 and Cdc42 using cDN

241 NSP1 can induce degradation of inactive and activated forms of IAD-containing IRF proteins (IRF3 to

242 to activate NF-kappaB, suggesting that only activated forms of IKK are relocalized.

243 Activated forms of jasmonic acid (JA) are central signal

244 tact, TCR microclusters are colocalized with activated forms of Lck, ZAP-70, and the linker for activ

245 iated inhibition prevented the generation of activated forms of LFA-1.

246 nonical Wnt signaling stimulated by Wnt1 and activated forms of LRP5 (low density lipoprotein recepto

247 Cellular localization of the activated forms of MAPKs, including extracellular signal

248 edium, is between the intermediate and fully activated forms of MMP-2 induced by membrane type 1-MMP.

249 rmined by analysis of the phosphorylated and activated forms of mTORC1 signaling proteins in the pref

250 n in cells lacking Abl kinases is rescued by activated forms of N-WASP.

251 MM cells from all the patients expressed the activated forms of NF-kappaB and STAT3 but to a variable

252 marrow of 22 MM patients and checked for the activated forms of NF-kappaB and STAT3 by immunocytochem

253 In contrast to MM patients, activated forms of NF-kappaB and STAT3 were absent in ce

254 and brain, we injected retroviruses encoding activated forms of Notch1, Notch2, or Notch3 into embryo

255 Although activated forms of Ras are frequently associated with on

256 Activated forms of Ras family members are prevalent in m

257 However, activated forms of Ras may also inhibit growth by induci

258 arily muscle-forming mesoderm, and expressed activated forms of Ras or Notch to induce FC or FCM fate

259 We show that, in Dictyostelium discoideum, activated forms of RasC prolong the time course of TORC2

260 ene, and it is also delayed by expression of activated forms of Rho, Rac and Cdc42.

261 Furthermore, expression of activated forms of Rho1p or Pkc1p, in the absence of cel

262 We expressed various activated forms of SOS2 in Saccharomyces cerevisiae (yea

263 Sugar nucleotides are activated forms of sugars used by the cell as donors for

264 misexpressing dominant-negative and dominant-activated forms of Tbx5 in the chick wing we provide evi

265 Activated forms of the Abl kinases (BCR-Abl, Tel-Abl, an

266 ted with high levels of immunoreactivity for activated forms of the BDNF receptor TrkB and beta1-inte

267 We also show that senescent cells contain activated forms of the DNA damage checkpoint kinases CHK

268 In addition, levels of activated forms of the kinase ERK and the transcription

269 tromal tumors (GISTs) express constitutively activated forms of the KIT receptor tyrosine kinase prot

270 ption factor lhx1a, and forced expression of activated forms of the lhx1a gene product rescued nephri

271 d imatinib resistance acquired expression of activated forms of the MET oncogene.

272 When crossed with mice expressing activated forms of the Neu receptor tyrosine kinase that

273 Although constitutively activated forms of the NOTCH1 receptor are potent induce

274 Cell type- or region-specific expression of activated forms of the oncoproteins Harvey-Ras and AKT i

275 Binding of activated forms of the proteinase inhibitor alpha2-macro

276 asses of FLT3 mutations cause constitutively activated forms of the receptor that are found in signif

277 Constitutively activated forms of the transmembrane receptor tyrosine k

278 Arrestins rapidly bind phosphorylated activated forms of their cognate G protein-coupled recep

279 Arrestins selectively bind to phosphorylated activated forms of their cognate G protein-coupled recep

280 t therapeutic use in cancers associated with activated forms of this kinase.

281 L-cmk decreased the nuclear content of SKI-1-activated forms of transcription factors SREBP-1, SREBP-

282 GF treatment results in the translocation of activated forms of TrkA to lipid rafts, and this localiz

283 Concomitant expression of activated forms of v-akt murine thymoma viral oncogene h

284 sformed by IL-27R contain elevated levels of activated forms of various signaling proteins, including

285 Furthermore, expression of activated forms of Xbp1 or Creb3l2 in animal explants co

286 Diabetic tissues are enriched in an "activated" form of human aldose reductase (hAR), a NADPH

287 rm a low-spin Fe(III) complex, the putative "activated" form of the drug, HOO-Fe(III)bleomycin.

288 n; and (iv) can engage the neddylated (i.e., activated) form of CUL3.

289 ncogenic stress and that the phosphorylated (activated) form of MSK1 is significantly increased in th

290 ocalization of the phosphorylated, therefore activated, form of cJun, a JNK target in dorsal root gan

291 rom an inactive cytosolic conformation to an activated form on membranes entails four distinct events

292 Here, we show that both CREB and its activated form pCREB-Ser(133) (pCREB) are reduced in the

293 between this PTM and levels of Akt2 and its activated form, phosphorylated serine-474 (p-Akt2).

294 creases total levels of STAT3 as well as its activated forms, resulting in decreased levels of the tu

295 enes that drive growth, targeting mutated or activated forms (such as the EGFR-Her2/Nneu pathway) has

296 In the pyruvamide-activated form, the loop located on the beta domain can

297 otoxins that require conversion to a smaller activated form to exert toxicity.

298 olon cancer and found STAT3, JAK3, and their activated forms to be frequently expressed.

299 ter migrating bands, indicating processed or activated forms, was confirmed at the protein level.

300 different solvents leads to two polymorphic activated forms with very different pore openings, marke