コーパス検索結果 (1語後でソート)
  通し番号をクリックするとPubMedの該当ページを表示します
  
   1 ely facilitates interaction with the agonist-activated form of a G-protein-coupled receptor (R*) and 
     2 ing CDX activity by ectopic expression of an activated form of a Xenopus Cdx gene (XcadVP16) in the h
  
  
  
     6 ng antibodies recognizing the phosphorylated/activated form of AKT kinases, we observed elevated phos
     7 nsgenic mice expressing a membrane-targeted, activated form of Akt under control of the 2',3'-cyclic 
     8  anti-apoptotic molecules and found that the activated form of Akt was suppressed in the E1A transfec
  
    10  characterized by combined overexpression of activated forms of AKT and neuroblastoma Ras viral oncog
  
    12 ells ectopically expressing a constitutively activated form of Akt3 or endogenously expressing mutant
    13 the TGF-beta signaling pathway by expressing activated forms of ALK-1 and ALK-5, type I receptors for
  
  
  
    17 precursor cells, we conditionally express an activated form of an FGF receptor or delete the FGF rece
    18 compound failed to significantly suppress an activated form of another RTK, the Drosophila epidermal 
    19  Moreover, the co-expression of Cat-1 and an activated form of Arf6 in fibroblasts was sufficient to 
    20 phila Arfaptin protein directly binds to the activated forms of Arf6 and Rac1 GTPases, and mutants in
    21 of furrow progression, can be mimicked by an activated form of armadillo and blocked by a dominant ne
    22  Studies in Drosophila have revealed that an activated form of Armadillo, the effector of Wnt signall
  
  
  
  
  
    28 sponse, characterized by the accumulation of activated forms of ATM and Chk2 as well as nuclear foci 
  
    30    In converse, conditional expression of an activated form of beta-Catenin leads to expansion of Nkx
  
    32 encoding either a stabilized, constitutively activated form of beta-catenin or a dominant negative fo
  
    34  gene transfer to force the expression of an activated form of beta-catenin that should constitutivel
    35 mportance, we have targeted expression of an activated form of beta-catenin to the urothelium of tran
  
  
    38 etroviral transduction of the constitutively activated forms of both GTPases into primary murine macr
    39 d in mice through the combined expression of activated forms of both KRas and Akt in glial progenitor
    40 (RCAS)/TVA system to transfer genes encoding activated forms of BRAF, KRas, Akt and Cre to nestin-exp
    41 ion has attracted considerable interest, and activated forms of BRAF, such as BRAF(V600E), have becom
  
    43 to constitutively express high levels of the activated form of c-jun N-terminal kinase (JNK), a membe
  
  
  
    47 o the cytoplasm and the nucleus, whereas the activated forms of calpain-7 and -10 are found only in t
    48 tion, whereas expression of a constitutively activated form of CaMKII mimicked the effects of morphin
    49 mmunohistochemical analysis reveals that the activated form of caspase-3 and a caspase cleavage produ
    50 nogenic soft agar assay and detection of the activated form of caspase-3 and cleavage of poly(ADP-rib
  
  
  
    54 genesis of C431 resulted in a constitutively activated form of CBS that could not be further activate
    55  Cat-1 from NIH3T3 fibroblasts expressing an activated form of Cdc42 (Cdc42 F28L), or from the human 
    56 sed an assay in yeast where expression of an activated form of Cdc42, a Rho-type guanosine triphospha
  
    58 Da protein that formed a stable complex with activated forms of Cdc42 and thereby showed characterist
  
    60   We demonstrate that CRL4(CDT2) targets the activated form of CHK1 for destruction in the nucleoplas
    61 ocalization of the phosphorylated, therefore activated, form of cJun, a JNK target in dorsal root gan
  
    63 nesis and lipolysis, forced expression of an activated form of CREBH protein in the liver significant
  
  
    66 uorescein, fluorescein and resorufin with an activated form of cyclic trimetaphosphate to give interm
    67 clease-coupled DNA methylation assay with an activated form of Dnmt1 engineered to lack the replicati
  
    69  three-dimensional structures of the apo and activated forms of DtxR show conformational changes in t
    70 ratin 14 promoter to target expression of an activated form of Edar in transgenic mice, we show that 
    71 tudies, the effects of a novel conditionally activated form of EGF-R, v-ErbB:ER, on the morphological
  
    73 somal maturation assay and observed that the activated form of EhRab35 significantly increased the ra
    74 ther contexts, and MsEphrin colocalizes with activated forms of endogenous Src in the leading process
    75 xide synthase (r(part) = 0.46, P = 0.02), an activated form of endothelial nitric oxide synthase.    
    76 gested that evaluation of the phosphorylated/activated form of ErbB-2 might be more precise in defini
    77 etastases of uveal melanoma patients express activated forms of ERBB2 (the coreceptor for ERBB3) and 
  
  
  
    81   Mutant tibiae have increased levels of the activated form of ERK1/2, consistent with the idea that 
  
    83 y, FHL2 interacted more efficiently with the activated form of ERK2 than with the dephosphorylated fo
    84 partate receptor subunit NR2B as well as the activated forms of extracellular signal-regulated kinase
  
  
    87 veral multiple myeloma cell lines expressing activated forms of FGFR3, NDGA generally resulted in a d
    88 efects are associated with low levels of the activated forms of focal adhesion kinase (FAK) and extra
  
  
    91 ed receptor kinases (GRKs) phosphorylate the activated form of G protein-coupled receptors leading to
    92 stins selectively bind to the phosphorylated activated form of G protein-coupled receptors, thereby b
    93 alian cells that these RhoGEFs interact with activated forms of G alpha 12 or G alpha 13 through thei
    94 ounced with the mutationally or functionally activated form of Galpha(13) compared to that of wild-ty
  
  
  
  
  
  
   101 ounced with the mutationally or functionally activated form of Galpha13 as compared with the wild-typ
  
  
   104   Conversely, expression of a constitutively activated form of GSK3beta sensitized cancer cells to mT
   105 he global gene expression pattern induced by activated forms of H-Ras, RhoA, Rac1 and Cdc42 using cDN
   106 e report that expression of a constitutively activated form of HIF2alpha (P405A, P530A, and N851A, na
   107 elets selectively lacking the G(beta)(gamma)-activated form of his enzyme (PI3Kgamma), we show that G
   108  of inhibitors shows higher affinity for the activated form of Hsp90 compared to our earlier 8-sulfan
  
  
  
   112  NSP1 can induce degradation of inactive and activated forms of IAD-containing IRF proteins (IRF3 to 
  
   114 We investigated whether mice that express an activated form of IKKbeta in the esophageal epithelia de
   115 uced platelet aggregation, expression of the activated form of integrin alphaIIbbeta3, and exposure o
   116 ells engineered to express human SERT and an activated form of integrin beta3 exhibited enhanced SERT
   117  the structural features associated with the activated form of Itk, we have solved the NMR structure 
  
  
  
  
  
   123 umors that developed in mice that express an activated form of Kras (Kras(LSL-G12D/+);Ptf1a(Cre/+) mi
  
   125 m with LSL-KRAS(G12D) mice, which express an activated form of KRAS and develop spontaneous pancreati
   126 2H/+);Pdx-1-Cre (KPC) mice, which express an activated form of Kras in pancreatic tissues, develop pa
   127 n the de novo synthesis of GDP-L-fucose, the activated form of L-fucose, which is a component of glyc
   128 tact, TCR microclusters are colocalized with activated forms of Lck, ZAP-70, and the linker for activ
   129 rved following overexpression of Pitx2 or an activated form of Lef1, suggesting an effect on cell pro
  
   131 nonical Wnt signaling stimulated by Wnt1 and activated forms of LRP5 (low density lipoprotein recepto
  
   133 ferentially interact with the phosphorylated/activated form of MAD, and Nup93 acts to recruit the imp
   134 defects due to loss of Msk are rescued by an activated form of MAPK or the secreted epidermal growth 
  
  
   137 xpressed dominant-negative or constitutively activated form of MEK5 to inhibit or activate the MEK5-E
   138 lls with CP-654577 reduces the levels of the activated form of mitogen-activated protein kinase, incr
   139 lpha/beta activity, and the expression of an activated form of MKK6 (an immediate upstream activator 
  
   141 edium, is between the intermediate and fully activated forms of MMP-2 induced by membrane type 1-MMP.
   142 ction in myogenic processes, we expressed an activated form of mouse calcineurin A in Drosophila and 
   143 ncogenic stress and that the phosphorylated (activated) form of MSK1 is significantly increased in th
   144 rmined by analysis of the phosphorylated and activated forms of mTORC1 signaling proteins in the pref
   145 yzed hydroacylation between aldehydes and an activated form of N=N bond was achieved under mild condi
  
  
   148 MM cells from all the patients expressed the activated forms of NF-kappaB and STAT3 but to a variable
   149 marrow of 22 MM patients and checked for the activated forms of NF-kappaB and STAT3 by immunocytochem
  
  
  
  
  
   155 -inducible manner, the ectopically expressed activated form of Notch1 (ICN1) displayed oncogene-like 
   156 l of Notch1 in solid tumors, we expressed an activated form of Notch1 (N1ICD) in the developing mouse
  
  
   159 :nicd1a transgenic embryos overexpressing an activated form of notch1, nicd1a, displayed increased cp
   160 ferent studies of transgenic mice expressing activated forms of Notch1 (Notch1IC) led to conflicting 
   161 and brain, we injected retroviruses encoding activated forms of Notch1, Notch2, or Notch3 into embryo
   162 n this study, we show that the effects of an activated form of Notch2 (N2IC) on the T-cell lineage ar
  
   164 conclude that there is no accumulation of an activated form of O2 before C-H abstraction in the Dbeta
  
  
   167 een previously demonstrated to represent an "activated" form of p53 in both in vivo and in vitro assa
  
   169 e-introducing expression constructs encoding activated forms of phosphoinositide 3-kinase, Akt, or Ak
   170      Subsequent studies demonstrated that an activated form of PI 3-kinase restored Rac GTP loading i
   171 , but not HIV infection alone, contained the activated form of PKR, which localized predominantly to 
   172 dy specific for the tyrosine-phosphorylated, activated form of PLCgamma1, we now show that chronic mo
   173 ing SKN-1, the MEDs, PAL-1, and the Wnt/MAPK-activated form of POP-1, are responsible for activating 
  
   175 cretion by strains containing a mutationally activated form of prfA, the key regulator of L. monocyto
   176 t that hES cells localize a conformationally activated form of proapoptotic BAX to the trans Golgi ne
  
   178 on of 3'-phosphoinositol lipids (PI3Ps), the activated form of Rac, a small GTPase, and F-actin.     
  
  
   181    We investigated whether expression of the activated form of Ras in gastric chief cells of mice lea
  
  
  
  
   186 arily muscle-forming mesoderm, and expressed activated forms of Ras or Notch to induce FC or FCM fate
  
   188   We show that, in Dictyostelium discoideum, activated forms of RasC prolong the time course of TORC2
  
  
  
  
  
   194 This phenotype can be recapitulated using an activated form of RhoA and rescued by inhibiting Rho-kin
   195 ns that bind with high affinity to the light-activated form of rhodopsin without requiring phosphoryl
  
   197 solid tumors, we established a conditionally activated form of ROCK II by fusing the kinase domain to
  
   199 luble guanylyl cyclase (sGC) itself, the NO -activated form of sGC, and phosphodiesterase(s) (PDE).  
   200 re known mutations predicted to result in an activated form of Shp2, whereas six are new mutations.  
   201      In this study, the biosynthesis of this activated form of sialic acid completely from endogenous
   202 antibody specific for the phosphorylated and activated form of Smad1 to examine endogenous patterns o
  
  
  
  
  
  
   209 ached high levels in the mother cell; (2) an activated form of Spo0A impaired sporulation when produc
  
  
   212 -Tyr containing proteins, an antibody to the activated form of Src-family PTKs was used to localize a
   213 othelial cell-specific overexpression of the activated form of SREBP2 synergized with hyperlipidemia 
   214   Stat3 protein levels and the levels of the activated form of Stat3 (pStat3) at P12, P15, P18, and P
  
   216 pression were increased by overexpressing an activated form of Stat3 but decreased by attenuation of 
   217 , while the introduction of a constitutively activated form of Stat3 into immortalized human breast e
   218 ereas the overexpression of a constitutively activated form of STAT3 promoted HSC senescence through 
   219  correlation between increased levels of the activated form of Stat3, phosphorylated-Stat3, and incre
   220 igodendrocytes; (2) the overexpression of an activated form of STAT5 prevents alpha-amino-3-hydroxy-5
   221  Transgenic mice expressing a constitutively activated form of STAT5b have been shown previously to c
  
   223 n addition, we demonstrate expression of the activated form of STAT6, a mediator of IL-4 signaling, b
  
   225 fonyl transfer, and nodPQ, which produce the activated form of sulfate, 3'-phosphoadenosine-5'-phosph
   226   These enzymes function together to produce activated forms of sulphate, APS and PAPS (3'-phosphoade
  
   228 the embryo and antagonizes the ability of an activated form of Tar/Acvr1b to induce endoderm at the a
   229 misexpressing dominant-negative and dominant-activated forms of Tbx5 in the chick wing we provide evi
   230 C-893 selectively killed cells expressing an activated form of the anabolic oncogene Ras in vitro and
   231 difier screen in the Drosophila eye using an activated form of the catalytic subunit to identify new 
   232 gulated by the polarized distribution of the activated form of the Cdc42 protein, rather than by the 
   233  Transgenic mice expressing a constitutively activated form of the cellular homologue Akt2 specifical
   234 ate that albicin specifically recognizes the activated form of the complex, allowing more efficient i
   235 neered to inducibly express a constitutively activated form of the cyclic AMP-dependent protein kinas
   236      Conversely, expressing a constitutively activated form of the Drosophila JAK kinase (hop(Tum-l))
  
   238 is required to stabilize the lifetime of the activated form of the enzyme against reoxidation of Fe(H
   239 ss spectrometry data show that the TIH-bound activated form of the enzyme closely resembles the inhib
   240 )(III) couple), the kinetic stability of the activated form of the enzyme has been greatly diminished
  
   242 hat while the thermodynamic stability of the activated form of the enzyme is unchanged (characterized
  
  
  
   246 ) to the Golgi complex is initiated when the activated form of the GTPase Sar1p recruits the Sec23p-S
   247 ted cells is rescued by the expression of an activated form of the immediate upstream p38-activating 
   248 d levels of expression of fibronectin and an activated form of the integrin alphavbeta3, which coordi
   249 Here, we describe a mouse line expressing an activated form of the K-Cl cotransporter Slc12a4 (Kcc1),
   250 ctive form of human rhodopsin bound to a pre-activated form of the mouse visual arrestin, determined 
   251 ne to enforce expression of a constitutively activated form of the Notch 4 receptor, we show that sig
   252 wo known clock components [Lfng mRNA and the activated form of the Notch receptor (cleaved Notch intr
   253 g the number of polar cells by expressing an activated form of the Notch receptor increases the numbe
   254  confirmed by misexpressing a constitutively activated form of the Notch receptor, Notch(IC), in tran
   255 ory progenitors, we transiently expressed an activated form of the Notch1 receptor (NICD) using a com
  
  
   258  dose-dependent manner by coexpression of an activated form of the nuclear kinase Sik/BRK that hyperp
  
   260 inant antibody (scFvSCE5), which targets the activated form of the platelet-integrin glycoprotein IIb
   261 s a crucial factor for stabilizing the light activated form of the protein, and have been used to pro
  
  
  
   265 he intracellular domain of Notch, a dominant activated form of the receptor, is sufficient to prevent
  
   267  steady-state level of the phosphorylated or activated form of the response regulator CheY dictates t
  
  
   270 ted with high levels of immunoreactivity for activated forms of the BDNF receptor TrkB and beta1-inte
   271    We also show that senescent cells contain activated forms of the DNA damage checkpoint kinases CHK
   272 IB point mutations also disrupt signaling by activated forms of the kinase cascade scaffold protein S
  
   274 tromal tumors (GISTs) express constitutively activated forms of the KIT receptor tyrosine kinase prot
   275 ption factor lhx1a, and forced expression of activated forms of the lhx1a gene product rescued nephri
  
  
  
   279  Cell type- or region-specific expression of activated forms of the oncoproteins Harvey-Ras and AKT i
  
   281 asses of FLT3 mutations cause constitutively activated forms of the receptor that are found in signif
  
  
  
   285 Arrestins selectively bind to phosphorylated activated forms of their cognate G protein-coupled recep
   286 bstrates and by detection of proteolytically activated forms of these caspases by Western immunoblott
   287 unt of PKMzeta protein and the amount of the activated form of this kinase, phospho-PKMzeta (p-PKMzet
  
  
  
   291 L-cmk decreased the nuclear content of SKI-1-activated forms of transcription factors SREBP-1, SREBP-
   292 isplay substantially increased levels of the activated form of transforming growth factor beta, a pot
   293 GF treatment results in the translocation of activated forms of TrkA to lipid rafts, and this localiz
  
   295      Furthermore, selective expression of an activated form of UNC-43 in ADF neurons is sufficient to
  
   297 sformed by IL-27R contain elevated levels of activated forms of various signaling proteins, including
  
   299 nic mice that overexpressed a constitutively activated form of YAP (YAP(S127A)), and measured protein
  
WebLSDに未収録の専門用語(用法)は "新規対訳" から投稿できます。