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1 osphate response element binding protein and activating transcription factor.
3 sponse element binding protein 1 (CREB1) and activating transcription factor 1 (ATF1) are closely rel
4 rthermore, we found that cdk3 phosphorylates activating transcription factor 1 (ATF1) at serine 63 an
5 sponsive element binding protein (CREB), and activating transcription factor 1 (ATF1) pathway is invo
6 esponsive element binding protein (CREB) and activating transcription factor 1 (ATF1), transcription
8 ic protein EWS-ATF1 (Ewing's sarcoma protein-activating transcription factor 1), which contains the D
10 ent of CREB transcription factors (CREB1 and activating transcription factor-1) in this functional re
12 3) cAMP-responsive binding protein (P-CREB), activating transcription factor-1, and CREB-induced CRE
14 rect regulation of transcription mediated by activating transcription factor 2 (ATF-2) and (ii) H(2)O
15 sphorylation of JNK, PKCdelta, p38 MAPK, and activating transcription factor 2 (ATF-2) in RA ST fibro
16 t the attachment of CREB binding protein and activating transcription factor 2 (ATF-2) to the cAMP-re
18 er showed an increase of Thr(P)-71-Thr(P)-69-activating transcription factor 2 (ATF2) binding in resp
21 y suppressing expression via binding through activating transcription factor 2 (ATF2) to the cyclic a
22 in transcription factors including c-jun and activating transcription factor 2 (ATF2) upon activation
23 -response element binding protein (CREB) and activating transcription factor 2 (ATF2), function as a
24 we identify four transcription factors, JUN, activating transcription factor 2 (ATF2), myocyte-specif
31 nstream effectors: phosphorylation of c-Jun, activating transcription factor 2, and E twenty-six-like
32 lation of the transcription factors, Jun and activating transcription factor 2, in addition to activa
33 ation of the transcription factors c-Jun and activating transcription factor 2, which in turn stimula
34 ylation of cAMP response-element binding and activating transcription factor 2, which leads to transa
36 at down-stream effectors of p38 MAPK, namely activating transcription factor-2 (ATF-2) and cyclic AMP
37 found that p38 target transcriptional factor activating transcription factor-2 (ATF-2) bound to ATF s
39 n transcription factors, including c-Jun and activating transcription factor-2 (ATF-2) upon activatio
42 we show that under non-stressed conditions, activating transcription factor-2 (ATF2) in cooperation
44 E(2) or Bt(2)cAMP + PDA stimulated c-Jun and activating transcription factor-2 (ATF2) phosphorylation
45 IFN regulatory factor-1 and upregulation of activating transcription factor-2 and c-Jun, transcripti
46 d activation of transcription factors c-Jun, activating transcription factor-2 and, in addition, NF k
48 reduced, there was no reduction in pulmonary activating transcription factor-2 expression, arguing ag
49 Investigation of JNK targets revealed that activating transcription factor-2 is phosphorylated unde
50 vation specifically activated c-Jun, but not activating transcription factor-2 or JunD, and increased
53 of p38 mitogen-activated protein kinase and activating transcription factor-2, which were blocked by
55 ressor of cytokine signaling 3 (SOCS-3), and activating transcription factor 3 (ATF-3), which termina
57 ic stress-induced UPR and cell death through activating transcription factor 3 (ATF3) and C/EBP homol
58 ound that microRNA-494 binds to the 3'UTR of activating transcription factor 3 (ATF3) and decreases i
59 C irradiation, immediate early genes such as activating transcription factor 3 (ATF3) are overexpress
62 8 mitogen activated protein kinase (p38MAPK)-activating transcription factor 3 (ATF3) dependent pathw
63 1) phosphorylation and subsequently enhances activating transcription factor 3 (ATF3) expression inde
85 roup of genes that appear to be regulated by activating transcription factor 3 (ATF3), a member of th
86 issue of Blood, Boespflug et al report that activating transcription factor 3 (ATF3), a member of th
92 or p75NTR, choline acetyltransferase (ChAT), activating transcription factor 3 (ATF3), and cleaved ca
93 itor of differentiation/DNA binding 2 (Id2), activating transcription factor 3 (Atf3), and the phosph
94 72 h after surgery, there is an increase in activating transcription factor 3 (ATF3), the neuropepti
95 expression of the transcriptional regulator activating transcription factor 3 (ATF3), which we show
100 ssociated with nerve injury and cell stress, activating transcription factor 3 and growth-associated
101 gly, four other genes, cylindromatosis, CD9, activating transcription factor 3 and oxytocin receptor,
102 d to activation of the transcription factors activating transcription factor 3 and protooncogene c-fo
105 dent, whereas induction of cystathionase and activating transcription factor 3 was Nur77 independent.
107 f the transcription factors c-Jun and ATF-3 (activating transcription factor 3), known regulators of
108 totic responses, including induction of p27, activating transcription factor 3, and nonsteroidal anti
109 ansection models, the upregulation of c-Jun, Activating transcription factor 3, Heat shock protein 27
112 amined a marker of cell injury/regeneration (activating transcription factor 3; ATF3), macrophage hyp
116 er transcripts, including neuropeptide Y and activating transcription factor-3, are upregulated norma
118 Several ER stress/UPR genes, including BiP, activating transcription factor 4 (ATF-4), ATF-6, and a
120 trends toward increasing downstream signals, activating transcription factor 4 (ATF4) and ATF6 indica
121 h preferential translation of mRNAs, such as activating transcription factor 4 (ATF4) and C/EBP-homol
122 UPR was activated, as the expression of both activating transcription factor 4 (ATF4) and CHOP (DDIT3
123 rotein synthesis but enhances translation of activating transcription factor 4 (ATF4) and is a crucia
125 ypes of mitochondrial stressors, we identify activating transcription factor 4 (ATF4) as the main reg
126 of FGF21 transcription was conferred by two activating transcription factor 4 (ATF4) binding sites i
127 sphorylation of eIF2alpha, which upregulates activating transcription factor 4 (ATF4) expression.
128 culum stress pathway, linked functionally to activating transcription factor 4 (ATF4) following treat
129 ed protein response (UPR) and an increase in activating transcription factor 4 (ATF4) has been previo
130 ve was to investigate the protective role of activating transcription factor 4 (ATF4) in controlling
132 d the signaling pathway of ER stress-induced activating transcription factor 4 (ATF4) in the regulati
139 ently that HRI also activates the eIF2alphaP-activating transcription factor 4 (ATF4) ISR in primary
141 and selectively enhances the translation of activating transcription factor 4 (ATF4) mRNA to induce
142 In contrast, obese mice lacking hepatic activating transcription factor 4 (Atf4) showed an exagg
143 a heme-regulated inhibitor kinase/eIF2alpha/activating transcription factor 4 (ATF4) signaling modul
144 protein kinase RNA-like ER kinase (PERK) or activating transcription factor 4 (ATF4) significantly r
145 istration of AP20187 significantly increased activating transcription factor 4 (ATF4) translation and
146 zed enzymes are transcriptionally induced by activating transcription factor 4 (Atf4) via C/ebp-Atf-R
147 expression of the bZip transcription factor activating transcription factor 4 (ATF4) was induced by
150 ancer-derived cells stimulated expression of activating transcription factor 4 (ATF4), a master trans
151 regulation of triglyceride metabolism by the activating transcription factor 4 (ATF4), a member of th
153 P response element binding protein 2 (CREB2)/activating transcription factor 4 (ATF4), a transcriptio
154 ulated by arsenite, in a manner dependent on activating transcription factor 4 (ATF4), an important m
155 X-box-binding protein-1 mRNA, expression of activating transcription factor 4 (ATF4), and cleavage o
156 master regulator of amino acid homeostasis, activating transcription factor 4 (ATF4), is dysfunction
158 ISC1 interacts with the transcription factor Activating Transcription Factor 4 (ATF4), which is invol
159 sion and purine synthesis were stimulated by activating transcription factor 4 (ATF4), which was acti
160 nts that the histone demethylase JMJD3 is an activating transcription factor 4 (ATF4)-dependent targe
170 on general control nonderepressible 2 kinase-activating transcription factor 4 (GCN2-ATF4) pathway ac
171 d early activation of the PKR-like ER kinase/activating transcription factor 4 (PERK/ATF4) ER stress
172 ed to persistent eif2-alpha phosphorylation (activating transcription factor 4 [ATF-4], C/EBP homolog
173 down of inositol-requiring enzyme 1alpha and activating transcription factor 4 abrogates autophagosom
174 initiation factor 2alpha phosphorylation and activating transcription factor 4 and C/EBP homologous p
175 factor 2alpha (eiF2alpha) and expression of activating transcription factor 4 and tribbles 3 were el
177 ugh arsenite treatment and is independent of activating transcription factor 4 signaling and protein
179 ulator homolog 1) was regulated by the ATF4 (activating transcription factor 4) arm of the unfolded p
180 f genes enriched for components of the ATF4 (activating transcription factor 4) arm of the unfolded p
183 response genes (C/EBP homologous protein and activating transcription factor 4), accumulation of cera
184 on by amino acid deprivation did not require activating transcription factor 4, a critical component
185 alpha, inositol requiring kinase 1alpha, and activating transcription factor 4, all of which are feat
186 such as the pseudokinase tribbles homolog 3, activating transcription factor 4, and transcription fac
187 er binding of the transcriptional activators activating transcription factor 4, C/EBPalpha, Runx1, an
188 luding glucose-regulated protein-78 (GRP78), activating transcription factor 4, growth arrest and DNA
189 rylated eukaryotic initiation factor-2alpha, activating transcription factor 4, inositol requiring ki
190 iation factor 2 (eIF2alpha) phosphorylation, activating transcription factor-4 (ATF4) induction, and
191 e proteasome inhibitor bortezomib, levels of activating transcription factor-4 increase dramatically
192 UPR induction, particularly up-regulation of activating transcription factor-4, CHOP (C/EBP homologou
196 th the heat shock protein 70 (HSP70) and the activating transcription factor 5 (ATF5) have been shown
199 h mouse and human BCR-ABL-transformed cells, activating transcription factor 5 (ATF5), a prosurvival
200 As a result, seven transcription factors-activating transcription factor 5 (ATF5), early growth r
205 nositol-requiring protein-1 (IRE1) alpha and activating transcription factor 6 (ATF6) arms of the UPR
210 ections were stained with antibodies against activating transcription factor 6 (ATF6) or activated ca
212 tases (OAS) genes, and selectively activated activating transcription factor 6 (ATF6), an unfolded pr
213 ol-requiring 1A/X box binding protein 1, and activating transcription factor 6 (ATF6), and each of th
214 binding protein 1 (XBP1) mRNA, activation of activating transcription factor 6 (ATF6), and protein ki
215 ions of three proximal sensors of ER stress: activating transcription factor 6 (ATF6), inositol requi
216 ates that DKK3 added as a cytokine activates activating transcription factor 6 (ATF6), leading to the
217 d accompanied by a reduction in the level of activating transcription factor 6 (ATF6), one of the tra
218 a cells induced the nuclear translocation of activating transcription factor 6 (ATF6), which is part
223 ress indexes in vivo and in vitro, decreased activating transcription factor 6 activation (cleavage,
224 nd X-box-binding protein 1 (XBP1) but not by activating transcription factor 6 alpha (ATF6alpha).
225 ty control genes through an association with activating transcription factor 6 alpha (ATF6alpha, also
226 , activating the transcription factor, ATF6 (activating transcription factor 6 alpha), which induces
227 ess proteins inositol-requiring enzyme 1 and activating transcription factor 6 and greater increases
228 ), which involves activation of the Ire1 and activating transcription factor 6 branches, but not the
229 tions of spliced X-box binding protein 1 and activating transcription factor 6 levels in affected liv
231 ion primary response gene 88), but not ATF6 (activating transcription factor 6) or XBP1 (X-box-bindin
232 lucose-regulated protein was down-regulated, activating transcription factor 6, and eIF2alpha were ac
235 e of dominant-negative versions of XBP-1 and activating transcription factor 6, the kinetics of class
236 onary circulation involves the activation of activating transcription factor 6, which, via induction
237 found to play a critical role in driving the activating transcription factor 6-mediated arm of this r
240 BP1) is selectively impaired in DN, inducing activating transcription factor-6 (ATF6) and C/EBP homol
241 augmented tunicamycin-induced activation of activating transcription factor-6 (ATF6) and induction o
242 ER kinase (PERK; official name EIF2AK3), and activating transcription factor-6, control the UPR.
244 ozygous mutations in the ATF6 gene (encoding activating transcription factor 6A), a key regulator of
246 tion factor involved in ER stress signaling, activating transcription factor 6alpha (ATF6alpha), thro
247 lasmic reticulum (ER) stress pathway through activating transcription factor 6alpha (Atf6alpha).
248 tol-requiring enzyme-1alpha (IRE1alpha), and activating transcription factor-6alpha (ATF6alpha)-were
249 tol-requiring protein-1alpha (IRE1alpha) and activating transcription factor-6alphaalpha (ATF6alpha).
250 activating transcription factor 2) and ATF7 (activating transcription factor 7) are highly homologous
253 pathways and the transcription factors ATF (activating transcription factor) and CREB (cyclic AMP re
254 PYD, pyrin N-terminal homology domain; ATF, activating transcription factor; and PTEN, phosphatase a
255 luding the bZip transcription factor atfs-1 (activating transcription factor associated with stress).
256 , we examined the mechanism by which ATFS-1 (activating transcription factor associated with stress-1
257 nse element (CRE)-binding protein (CREB) and activating transcription factor (ATF) 1 contributes to m
258 eport that anisomycin, a potent activator of activating transcription factor (ATF) 2, and c-Jun-NH(2)
259 meric complexes with the AP-1 family members activating transcription factor (ATF) 2, ATF3, and ATF7.
260 -1 significantly inhibited the expression of activating transcription factor (ATF) 3, a member of the
261 tiation factor 2, and increased synthesis of activating transcription factor (ATF) 4 by a translation
262 identified CHOP as an interacting partner of activating transcription factor (ATF) 4 in a yeast two-h
263 anced levels of phosphorylated eIF2alpha and activating transcription factor (ATF) 4, which is essent
264 ern and the role of different members of the activating transcription factor (ATF) family in survival
265 tion factors are dimers of JUN, FOS, MAF and activating transcription factor (ATF) family proteins ch
266 CREB3L1), a transcription factor of the CREB/activating transcription factor (ATF) family, increases
267 -AMP response element binding protein (CREB)/activating transcription factor (ATF) site overlapping a
268 -related protein (SMAD)-3 (nt -584 to -581), activating transcription factor (ATF)-2 (nt -571 to -568
270 site 2 bound CRE-binding protein (CREB) and activating transcription factor (ATF)-2 in vitro and was
272 equires binding sites for sequence-dependent activating transcription factor (ATF)-adenosine 3',5'-mo
275 developing heart and somites via one or more activating transcription factor (ATF)/cyclic AMP respons
276 kinase and downstream components, including activating transcription factor (ATF)/cyclic AMP-respons
278 f type I IFN gene expression, interacts with activating transcription factor (ATF)4, a key component
279 RAD is increased by the ER stress modulator, activating transcription factor (ATF)6, which can induce
280 expression of the transcriptional repressor activating transcription factor (ATF-3) in a STAT1-depen
281 kinase and PKR-like ER kinase (PERK)-induced activating transcription factor (ATF3) binding to its pr
284 c (Tg) mice constitutively expressing B cell-activating transcription factor (BATF), a basic leucine
287 cts of cAMP response element binding protein/activating transcription factor (CREB/ATF) and AP-1 tran
290 1) family transcription factor BATF (B cell, activating transcription factor-like) was among the gene
291 ression mediated, in part, by members of the activating transcription factor protein (AP1) group.
292 h defects in IFN regulatory factor 4, B cell-activating transcription factor, retinoic acid-related o
294 Hep3B cells, IL-6 induces CRP expression by activating transcription factors STAT3 and C/EBPbeta.
295 nhibition can increase cAMP and cGMP levels, activating transcription factors such as the cAMP respon
296 ndelian disease, we show that DNA binding of activating transcription factor (TF) determines histone
297 reasing histone deacetylase activity, or (e) activating transcription factors that antagonize chronic
298 drial ROS augmented the expression of B cell-activating transcription factor, which may contribute to
299 ified a cellular repressor of transcription, activating transcription factor x (ATFx), as a novel Tax
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