ライフサイエンスコーパス: activator

1 ently as a high hierarchical transcriptional activator.

2 city-enhancing factor, and potent allosteric activator.

3 C1r and C1s, induced upon C1 binding to the activator.

4 as both a membrane anchor and an allosteric activator.

5 presence of Mg(2+) , ATP is inadequate as an activator.

6 n (Ang) ligands, with Ang1 being its primary activator.

7 otoxin is a potent small-molecule BK channel activator.

8 on molecule-1 and urokinase-type plasminogen activator.

9 matory cytokines, as well as an inflammasome activator.

10 f PTBP1 and its role as a bona fide splicing activator.

11 dependently of BST2, VP40 is the more potent activator.

12 ascades of signal-responsive transcriptional activators.

13 IL-1beta in vivo in response to inflammasome activators.

14 ng a CARD (ASC) protein in response to NALP3 activators.

15 P and G6P work synergistically as allosteric activators.

16 stance to therapy by suppressing BAX and its activators.

17 ng genes encoding neuroblast transcriptional activators.

18 vity of mERbeta isoforms with EDCs and ER co-activators.

19 tained within the CRY2-fused transcriptional activators.

20 n and ninein-like are a new family of dynein activators.

21 , particularly when combined with other ILC2 activators.

22 rescued by treatment with small-molecule CMA activators.

23 gates the function of CRISPR-transcriptional activators.

24 en to plasmin in the presence of plasminogen activators.

25 l cues that regulate certain transcriptional activators.

26 lieve neuropathic pain, we synthesized novel activators (4a-f) of EAAT2.

27 e the role of an AMP-dependent kinase (AMPK) activator, 5-aminoimidazole-4-carboxamide riboside (AICA

28 We show that the selective Epac activator 8-(4-chloro-phenylthio)-2'-O-methyladenosine-3

29 V) axes, respectively, by spatially limiting activator action, but here we characterize a different r

30 lective K2P2.1 (TREK-1) and K2P10.1 (TREK-2) activators-an N-aryl-sulfonamide, ML335, and a thiophene

31 m of MAPK activation requiring binding of an activator and also shows that MAPKs can be diversified t

32 The B-cell receptor transmembrane activator and calcium modulator ligand interactor (TACI)

33 h-affinity ligand for BCMA and transmembrane activator and calcium-modulator and cyclophilin ligand (

34 , B cell maturation Ag (BCMA), transmembrane activator and CAML interactor, and BAFF receptor, in sor

35 egates interact with tissue-type plasminogen activator and plasminogen, via an exposed lysine-depende

36 These data unveil TBK1 as a direct mTORC1 activator and suggest unanticipated roles for mTORC1 dow

37 y depended on the strength of the complement activator and the resulting surface density of the compl

38 spite unaltered protein interactions with co-activators and -repressors.

39 al scavengers, antimicrobials, estrogen-like activators and acetylcholinesterase/tyrosinase inhibitor

40 le the assessment of the effects of clotting-activators and anticoagulants (including non-pharmacolog

41 neering and screening approaches to identify activators and blockers with strong, specific binding fo

42 omoters by sequence-specific transcriptional activators and by chromatin modifications to promote pre

43 mmune system, by controlling transcriptional activators and downstream cytokines, to affecting their

44 works, composed of phase-specific cell-cycle activators and inhibitors.

45 was related to an increase in specific BMPR2 activators and/or a reduction in inhibitors, and the imp

46 ate small molecules that turn on the enzyme (activator) and turn off the activation (blocker).

47 s that are proximately causal, upstream risk activators, and risk markers.

48 es, reporters, and inducible transcriptional activators are key for many genetic studies and comprise

49 e-lowering agents, and the development of GK activators are now considered as one of the most promisi

50 mechanisms of action, such as cardiac myosin activators, are under investigation for patients with he

51 e catalytic domain (DHPH domain) of the RhoA activator ARHGEF11 to CRY2-mCherry (optoGEF-RhoA) and en

52 tural basis for further development of Sirt6 activators as tools and therapeutics.

53 nhibitor, prevented BCL-XL from sequestering activator BH3-only molecules (BH3s) and BAX but not BAK.

54 ntire SAGA complex where the major target of activator binding, the 430 kDa Tra1 protein, is resolved

55 cement from the heme iron can be affected in activator-bound CYP46A1.

56 l rate of [Ca(2+) ]i rise induced by the RyR activator caffeine without significantly affecting the c

57 calmodulin, calmodulin-binding transcription activators (CAMTA)3 and calmodulin binding protein 60g (

58 relies on a defined exogenous transcription activator capable of binding a unique recognition sequen

59 Screening for activators capable of synergizing with HMGN1 in activati

60 Low NF-kappaB activators cause more severe lung infections in mice, an

61 Plk1, which triggers association with the co-activator CBP.

62 NAs, whereas concentrations of the T-cell co-activators CD80 and CD86 increased in parallel with redu

63 the size-dependent expression of the mitotic activator Cdc25.

64 inly in neuronal contexts, when using the co-activator Cdh1/Fzr.

65 hase-III (the catalytic subunit Chs3 and its activator Chs4), respectively [18, 19].

66 of so-called soluble guanylate cyclase (sGC) activators, cinaciguat and BAY 60-2770 are interesting t

67 The transcription co-activator complex SAGA is recruited to gene promoters by

68 ed factor complex (PAFc) is an epigenetic co-activator complex that makes direct contact with MLL fus

69 on CCC1 transcription, suggesting that other activators contribute to the regulation of CCC1 transcri

70 g protein (Creb1) and its transcriptional co-activators (Crtc1-3) as targets of miR-17, miR-144, and

71 ced transcription from constitutive, but not activator-dependent, promoters.

72 strategy is a first step towards developing "activator drugs" for a large number of genetic disorders

73 1mg of recombinant human tissue plasminogen activator every 8 hours until clot clearance of third an

74 ncentration of the unbounded transcriptional activator ExsA.

75 Methylation of the phosphatase-transcription activator EYA1 by protein arginine methyltransferase 1:

76 ere treated with IVT with tissue plasminogen activator followed by MT (IVT and MT group) with the use

77 t TGF-beta1 and myocardin (MYOCD) are potent activators for VSMC differentiation, we screened for TGF

78 hermore, treatment with the adenylyl cyclase activator forskolin diminishes cytosolic localization of

79 ifically at the level of GLI transcriptional activator function.

80 such as organic nitriles, the prototype TAML activator gave the structurally authenticated reactive i

81 We report the mTOR activator gene RHEB as an ID gene that is associated wit

82 n increase in the downstream transcriptional activator GLI1 and a decrease in the GLI3 transcriptiona

83 apbeta2 is required for the formation of Gli activator (GliA) in wild-type but not in Sufu mutant cel

84 rameters, the discovery of selective, direct activators has proven challenging.

85 Protein-based biosensors or activators have been engineered to visualize molecular s

86 by both the nature of the endogenous mGluR1 activator (i.e., endogenous biased agonism at mGluR1) an

87 ity to the mRNA for the important viral gene activator ICP0, inhibition of ICP0 expression by miR-H2

88 metabolism, acting as its transcriptional co-activator in endothelial cells.

89 Research shows that resveratrol, a sirtuin activator in red wine, improves exercise endurance and s

90 al repressor and TgSOC1-like2 being a floral activator in tulip.

91 We developed methods to identify new activators in our BioID data, and discovered that ninein

92 Known Nrf2 activators increased SREBP-1C promoter reporter activity

93 ch we previously identified as a novel HIF-1 activator, increased the radioresistance of cancer cells

94 control, n = 10), expression of plasminogen activator inhibitor 1 (PAI-1), a key enzyme in the fibri

95 matrix degradation by increased plasminogen activator inhibitor 1.

96 ly it has been demonstrated that plasminogen activator inhibitor serpins promote brain metastatic col

97 Increased levels of plasminogen activator inhibitor type I (PAI-1) have been shown to pr

98 Plasminogen activator inhibitor-1 (PAI-1) is known to protect mice a

99 n infected mice that overexpress plasminogen activator inhibitor-1 (PAI-1), S. aureusclfA expression

100 atterns emerge via self-organization from an activator-inhibitor network, in which the small GTPase R

101 patterning is controlled by the BMP/Chordin activator/inhibitor system.

102 degradation of STAT3, a master transcription activator involved in multiple cellular processes and th

103 racterization of a novel series of autophagy activators involving fatty acid cysteamine conjugates.

104 s rt-PA (recombinant tissue-type plasminogen activator) is effective in improving outcomes in ischemi

105 ophosphate receptor protein (CAP), a classic activator, is able to activate transcription independent

106 ed by the KSHV replication and transcription activator (K-Rta).

107 2-myristate 13-acetate, two protein kinase C activators, leads to altered morphology which otherwise

108 Transcription activator-like (TAL) effectors from Xanthomonas citri su

109 r system based on programmable transcription activator-like effector (TALE) proteins, which enables p

110 over, we developed a multiplex transcription activator-like effector activation (mTALE-Act) system fo

111 nc finger proteins (ZFP), four transcription activator-like effector proteins (TALE), CRISPR associat

112 or TET1-CD and CIB1 fused to a Transcription Activator-Like Element (TALE) locating an Ascl1 promoter

113 11 lncRNA loci that, upon recruitment of an activator, mediate resistance to BRAF inhibitors in huma

114 HIFs), a family of essential transcriptional activators mediating the metazoan hypoxic response.

115 as also inhibited by the direct GIRK channel activator ML297, whereas blocking these channels with ba

116 ithin newly identified gamma-TuRC nucleation activator motifs.

117 eased expression of progesterone receptor co-activators (NCOA1, -2 and -3, and CREBBP) towards term i

118 It was activated by the BKCa channel activator NS1619 (30 mum).

119 K19 versus shCTRL) were treated with the p53 activator nutlin-3.

120 ified tacrolimus (FK-506) as the most potent activator of ALK1 signaling in BMP9-challenged C2C12 rep

121 hibits the conversion of AICAR to the direct activator of AMPK, ZMP, did not reverse the effects on T

122 tol hexakisphosphate (IP6) is a non-receptor activator of arrestin-3 and report the structure of IP6-

123 show that the protein ETAA1 is an important activator of ATR in human cells, providing insights into

124 creted protein, it is an autocrine/paracrine activator of canonical WNT signaling and, as an intracel

125 egulatory subunit 1a (cdk5r1a), an essential activator of Cdk5.

126 Thus identifying the epigenetic activator of ERalpha that can be targeted to block ERalp

127 n activator (tPA) is the major intravascular activator of fibrinolysis and a ligand for receptors inv

128 YY1 acts both as a repressor and as an activator of gene expression.

129 Here, we find that the cochaperone, activator of Hsp90 ATPase homolog 1 (Aha1), dramatically

130 ICP34.5 and TANK-binding kinase 1 (TBK1), an activator of IFN responses.

131 Z-DNA-binding protein 1 (ZBP1)/DNA-dependent activator of IFN-regulatory factors (DAI) that contain r

132 ent failure to function as a transcriptional activator of Il1a expression.

133 the liver by the GTPase ARF1, which is a key activator of lipolysis.

134 thways and pinpoint PREX1 as an AML-specific activator of MAPK signaling.

135 (PGC-1alpha), a critical transcriptional co-activator of metabolic gene expression, functions to dow

136 Disheveled-associated activator of morphogenesis (DAAM) is a diaphanous-relate

137 tream effector Daam1 (Dishevelled associated activator of morphogenesis 1), and functionally suppress

138 that CFIm functions as an enhancer-dependent activator of mRNA 3' processing.

139 f G-protein signaling Gbeta5-R7 is a crucial activator of muscarinic M3 receptor-stimulated insulin s

140 , and is therefore termed Linc-RAM (Linc-RNA Activator of Myogenesis).

141 xpression and responsiveness of the receptor activator of NF-kappaB (RANK), which is central for mTEC

142 Binding of receptor activator of NF-kappaB ligand (RANKL) to its receptor RA

143 s(2-hydoxybenzylidene)acetone (HBB2), a dual activator of NRF2 and HSF1, protects against the develop

144 ents revealed that stimulation with receptor activator of nuclear factor kappa-B ligand (RANKL) resul

145 sponse activated T cells to produce receptor activator of nuclear factor kappa-B ligand (RANKL), whic

146 of nuclear factor kappaB receptor, receptor activator of nuclear factor kappaB ligand/macrophage col

147 Despite higher expression of the receptor activator of nuclear factor kappaB receptor, receptor ac

148 whether IL-12 affects expression of receptor activator of nuclear factor-kappa B (NF-kappaB) ligand (

149 of osteoblasts and osteoclasts, and receptor activator of nuclear factor-kappa B ligand (RANKL) activ

150 unt-related transcription factor-2, receptor activator of nuclear factor-kappa B ligand (RANKL), scle

151 lthy teeth (P = 0.003), and soluble receptor activator of nuclear factor-kappaB ligand (sRANKL) conce

152 regulates Id2, the repressor of the receptor activator of nuclear factor-kappaB ligand-mediated osteo

153 Streptococcus mutans - SpxA1 was the primary activator of oxidative stress genes whereas SpxA2 served

154 IV TAR RNA-binding protein (TRBP) or protein activator of PKR (PACT), while Drosophila Dicer-1 associ

155 SARD1 is an activator of plant immunity that promotes production of

156 quencing analysis suggesting that Xpp1 is an activator of primary metabolism.

157 Deletion of ArcZ, a small RNA activator of RpoS, decreased biofilm in YESCA; only a po

158 , converting Musashi2 from a repressor to an activator of target mRNA translation.

159 a dual regulator of cmr transcription and an activator of the divergent rv1676 gene.

160 ium-sensor calmodulin (CaM) acts as a common activator of the networks responsible for both LTP and L

161 FDA approved drug hydralazine is a bona fide activator of the NRF2/SKN-1 signaling pathway.

162 Here we demonstrate that HQ is an activator of the peripheral irritant receptor transient

163 uggested that VRS3 acts as a transcriptional activator of the row-type genes VRS1 (Hv.HOMEOBOX1) and

164 Laboratory studies show that lithium, an activator of the Wnt/ss-catenin signaling pathway, slows

165 et al. (2017) have discovered that Std1, the activator of the yeast AMP kinase Snf1, condensates into

166 yang 1 (YY1)-associated protein 1 and is an activator of the YY1 transcription factor.

167 (2-thienyl)-L-alanine (TIH) as an allosteric activator of this enzyme.

168 rly phosphorylation of signal transducer and activator of transcription (STAT) 1 and STAT3, which is

169 vated site (GAS)-like, signal transducer and activator of transcription (STAT) binding elements (SBEs

170 Janus kinase (JAK) and signal transducer and activator of transcription (STAT) mutations have been di

171 hich signals through a Signal transducer and activator of transcription (STAT) protein to promote cel

172 on of Janus kinase and signal transducer and activator of transcription (STAT) signaling contributes

173 the Janus kinase (JAK)/signal transducer and activator of transcription (STAT) signaling pathways is

174 GF165b inhibits VEGFR1 signal transducer and activator of transcription (STAT)-3 signaling to decreas

175 histamine enhanced the signal transducer and activator of transcription (STAT)-6 phosphorylation leve

176 The signal transducer and activator of transcription (STAT)5 activation in left ve

177 scriptional regulator, signal transducer and activator of transcription (STAT1), via an IFN-independe

178 he neurotoxic HIV-1 regulatory protein trans-activator of transcription (Tat) continues to be express

179 directly by modulating signal transducer and activator of transcription 1 (STAT1) and utilizing its S

180 mutations in the human signal transducer and activator of transcription 1 (STAT1) manifest in immunod

181 d incubated with IL28; signal transducer and activator of transcription 1 (STAT1) phosphorylation was

182 n at the SUMO motif on signal transducer and activator of transcription 1 (STAT1).

183 gher levels of phospho-signal transducer and activator of transcription 1 in the liver and spleen and

184 ependent mechanisms of signal transducer and activator of transcription 1 signaling and dsRNA viral s

185 Signal transducer and activator of transcription 3 (STAT3) is a pleiotropic si

186 ed B cells (NF-kappaB)/signal transducer and activator of transcription 3 (STAT3) signaling pathway a

187 clear translocation of signal transducer and activator of transcription 3 (STAT3), reduces STAT3 bind

188 phosphorylation of the signal transducer and activator of transcription 3 (STAT3).

189 helial cells activates signal transducer and activator of transcription 3 and mitogen-activated prote

190 rodent T-cell lymphoma/signal transducer and activator of transcription 3 pathway in keratinocytes.

191 regulation of Jak2 and signal transducer and activator of transcription 3 phosphorylation and the exp

192 panied by an increased signal transducer and activator of transcription 3 phosphorylation, reduced IL

193 expression mediated by signal transducer and activator of transcription 3 through an IL-23/acutely tr

194 with or without STAT3 (signal transducer and activator of transcription 3) inhibitor S3I-201 for peri

195 ession was mediated by signal transducer and activator of transcription 4 and NF-kappaB signaling pat

196 hepatic growth hormone-signal transducer and activator of transcription 5 (GH-Stat5) signaling compar

197 eficiency impaired the signal transducer and activator of transcription 5 (STAT5) pathway in Foxp3(+)

198 kt (PI3K-Akt) pathway, signal transducer and activator of transcription 5 (STAT5), and the Mek-Erk pa

199 anonical activation of signal transducer and activator of transcription 5 (STAT5).

200 l-transducing molecule signal transducer and activator of transcription 6 (STAT6) and evaluated the e

201 enhanced IL-13-driven signal transducer and activator of transcription 6 activation.

202 ted protein kinase and signal transducer and activator of transcription signaling, and interactions o

203 aling and Janus kinase-signal transducer and activator of transcription signaling.

204 rs (TFs) of the STAT ('signal transducer and activator of transcription') family constitute a rapid m

205 ion factors, including signal transducer and activator of transcription-1 (STAT1).

206 ediated stimulation of signal transducer and activator of transcription-3 (STAT3).

207 s kinase signaling via signal transducer and activator of transcription.

208 like all previously reported genes acting as activators of basal bud initiation, SPL4 acts as a suppr

209 only organisms with both WASP and SCAR/WAVE-activators of branched actin assembly-make actin-filled

210 and DLX2 function as direct transcriptional activators of Brn3b expression.

211 ponents of NETs have also been implicated as activators of coagulation.

212 databases of astrocyte exposed to well-known activators of CREB-dependent transcription as well as pu

213 receptor-induced signaling pathways are key activators of host antifungal immunity, little is known

214 l screen in zebrafish that identifies GCs as activators of hypoxia-inducible factors (HIFs) in the li

215 ed less IL-1alpha in response to particulate activators of inflammasome.

216 t e1a regulates the stabilities of these key activators of innate immune responses, as shown directly

217 there is significant interest in developing activators of KCC2 as therapeutic agents.

218 cription factors NLP6 and NLP7, which act as activators of nitrate assimilatory genes, bind to adjace

219 New analogues are also shown to be selective activators of NOD2 and NLRP3 (inflammasome) in vitro but

220 series of orally bioavailable small molecule activators of PP2A, termed SMAPs.

221 oth directly target STAT3/5, transcriptional activators of TET1, and thus repress TET1 expression.

222 ions, which are known to interact with other activators of the classical pathway.

223 However, by allowing expression of activators of the cytotoxic program, this inhibitory mec

224 eutralize anticoagulant activity and inhibit activators of the intrinsic blood clotting pathway, such

225 lasts showed that OsPCF2 and OsNIN-like4 are activators of the OsNHX1 gene expression, while OsCPP5 a

226 ing in brain endothelial cells, but upstream activators of this disease pathway have yet to be identi

227 ng important (patho)physiologically relevant activators of this pathway.

228 species CM3 and 0.19 were the most prevalent activators of TLR4 in modern wheat and were highly resis

229 Signal transducers and activators of transcription 5 (STAT5s) are crucial effec

230 ent toward the development of small molecule activators of tumor suppressor proteins.

231 A key insight is that activators often work combinatorially, allowing signal i

232 iation, blocking the action of a promiscuous activator on cryptic promoters is a critical mechanism f

233 d TEs can function as either transcriptional activators or repressors.

234 eated cells also had higher amounts of small activators PA28alphabeta and PA28gamma bound to 20S part

235 d combined effects of the vitamin D receptor activator paricalcitol (PARI) and dietary sodium restric

236 r the Hf pre-catalyst in the presence of the activator [Ph3C][B(C6F5)4].

237 and 5hmC was confirmed by adenylate cyclase activators, phosphodiesterase inhibitors, and most notab

238 Nek6, as well as its upstream activators polo-like kinase 1 and Aurora-A, targeted Hsp

239 of the adipogenic regulator PPARG and its co-activator PPARGC1B, and reduced expression of LPL.

240 of CO rebinding to carbon monoxide oxidation activator protein (ChCooA) are measured over a wide temp

241 omplement of a gene encoding a transcription activator protein (TrAP).

242 we identified several functional NF-kappaB, activator protein 1 (AP1), STAT, and Smad DBS in the TSL

243 ceptor gamma agonist rosiglitazone decreased activator protein 1 promoter activity.

244 ough serine 84 phosphorylation and promoting activator protein 1 transcription.

245 ed gene regulation and another way that this activator protein can repress protein expression.

246 ns with known roles (CAPS [calcium-dependent activator protein for secretion 1], Munc13-2, RIM1, and

247 -bound sites by the SAP domain-containing co-activator protein myocardin, and we show that paired sit

248 Here we show the activator protein-1 (AP-1) factor JunB is an essential r

249 The transcription factor, activator protein-1 (AP-1), binds to cognate DNA under r

250 V6 expression is through EGR1-mediated AP-1 (activator protein-1) activity and that the EGR1- and AP-

251 hibitor with enhanced affinity for circadian activator proteins Clock and Bmal1.

252 es, neurofibromin1 (Nf1) and RAS p21 protein activator (Rasa1).

253 on binding to the urokinase-type plasminogen activator receptor (uPAR) catalyzes the conversion of pl

254 , including CD73, urokinase-type plasminogen activator receptor (uPAR), and serum amyloid A2 (SAA2),

255 omarkers, soluble urokinase-type plasminogen activator receptor, suPAR and neutrophil gelatinase-asso

256 us thrombolysis with tissue-type plasminogen activator remains the mainstay of acute stroke therapy w

257 Notably, both activators require the membrane phospholipid PIP2 but ap

258 ple, the NCoR/SMRT complex), transcriptional activators, RNA, chromatin remodellers, microRNA-process

259 e KSHV protein replication and transcription activator (RTA) and during spontaneous reactivation.

260 ranscription activity and in maintaining the activator sensitivity of sigma(N).

261 Surprisingly, the addition of an activator site often reduces expression.

262 An SK channel activator (SKA-31) decreased contractions during filling

263 anism of the human CRAC channel Orai1 by its activator, stromal interacting molecule 1 (STIM1).

264 scriptional activators via recruitment of co-activators such as EP300, whereas KLF3 and related membe

265 t Tra1 subunit is the major target of acidic activators such as Gal4, VP16, or Gcn4 but little is kno

266 omotetramers, promoted by anionic allosteric activators such as inorganic phosphate.

267 hages that have been exposed to inflammasome activators, such as bacteria and their products or host-

268 The existing KCa activators, such as naphtho[1,2-d]thiazol-2-ylamine (SKA

269 thrombolytic therapy with tissue plasminogen activator (t-PA).

270 A point mutation in the Gal1 co-activator that disrupts the interaction with the Gal80 i

271 Although p53 is a transcriptional activator that induces myriad target genes, those p53-in

272 .Omecamtiv mecarbil (OM) is a cardiac myosin activator that is currently in clinical trials for heart

273 scribe its oncogenic role as a HIF-1alpha co-activator that regulates the HIF-1 transcriptional netwo

274 herpesvirus-specific Us3 kinase as an mTORC1 activator that subverts the host cell energy-sensing pro

275 Androgen receptor (AR) is a transcriptional activator that, in prostate cells, stimulates gene expre

276 ing protein (CBP) are key transcriptional co-activators that are essential for a multitude of cellula

277 here is a binding platform for translational activators that regulate translation in yeast but not ma

278 ressing the activity of bHLH transcriptional activators that together are required to achieve precise

279 Rho amplifies its activity by recruiting its activator, the guanine nucleotide exchange factor GEF-H1

280 n that is itself inhibited by the cell-cycle activator, their interaction network presents a regulato

281 d r-tPA (recombinant tissue-type plasminogen activator) therapy may be required, despite its bleeding

282 nzylamines react with boronic esters and a N-activator to afford ortho-substituted benzylic boronic e

283 tion in part by controlling the access of co-activators to their transcription factor partners.

284 c enzymes, urokinase, and tissue plasminogen activator (TPA) as a source for plasmin formation.

285 Tissue-type plasminogen activator (tPA) is the major intravascular activator of

286 brinolytic enzyme such as tissue plasminogen activator (tPA).

287 mber of synapses after treatment with a PERK activator, tunicamycin.

288 matic activity of urokinase-type plasminogen activator (uPA) and matrix metalloproteinase-2 (MMP-2).

289 th suppression of urokinase-type plasminogen activator (uPA) and the uPA receptor in AECs from the lu

290 Urokinase-type plasminogen activator (uPA) is a serine proteinase that upon binding

291 cal target of SerpinB2-urokinase plasminogen activator (uPA).

292 d family members function as transcriptional activators via recruitment of co-activators such as EP30

293 ded phosphatidylinositol 3-kinase (PI3K)-Akt activator, was dependent upon the Ser/Thr kinase activit

294 screening of potential GLUT5 inhibitors and activators, while the latter enables detailed kinetic ch

295 YAP is a mechanosensitive transcriptional activator with a critical role in cancer, regeneration,

296 (4%) received intravenous tissue plasminogen activator without complications.

297 uggested that intravenous tissue plasminogen activator would be delayed by 12 minutes, but MT would b

298 nd inhibit the downstream transcriptional co-activators YAP and TAZ, which are implicated in various

299 ds to phosphorylation of the transcriptional activator yes-associated protein 1 (YAP1, YAP), which re

300 The zinc-responsive transcription activator Zap1 plays a central role in zinc homeostasis