コーパス検索結果 (1語後でソート)
通し番号をクリックするとPubMedの該当ページを表示します
2 ts macrophage ability to sustain cancer cell activities as a major concern that needs to be addressed
3 ment of strategies to reduce their levels or activities as a new approach for preventing thrombosis.
4 gical assays that confirm that it has potent activities as a new colchicine site microtubule depolyme
6 memory targets and implicate persistent FEF activity as a basis for the interdependence of working m
9 a, can change the balance between H pylori's activity as a commensal or a pathogen has provided direc
10 at GPC3 can modulate the PCSK9 extracellular activity as a competitive binding partner to the LDLR in
12 ulating character, they show electrochemical activity as a consequence of the presence of different f
15 rvation response and implicate WTA hydrolase activity as a determinant of functional properties of th
16 naB function in DNA replication, but not its activity as a DNA helicase or its ability to bind to ssD
18 cutaneous melanoma biopsies, arguing for COX activity as a driver of immune suppression across specie
19 e potential importance of NLRP3 inflammasome activity as a driving force for inflammation in MLKL-dep
22 hat blunted development of reward-related VS activity as a function of emotional neglect predicts the
23 describe an assay to measure neuronal GIRK2 activity as a function of membrane-anchored G protein co
24 ual cortex and measuring changes in neuronal activity as a function of stimulation intensity, with or
26 mote spatial group selection of granule cell activity as a function of timing of mossy fiber input.
27 level differences in memory encoding-related activity as a function of women's reproductive stage, in
28 t, in particular with increased inflammatory activity as a hallmark of the tumor milieu that goes alo
29 these residues by arginine enhances polyQ AR activity as a hormone-dependent transcriptional regulato
31 ur results implicate DAF-3 repressor complex activity as a key molecular mechanism whereby the enviro
32 my, revealing a new function for EGFR kinase activity as a lipid metabolism regulator in regenerating
34 ixDC-MEL) are immunogenic and have antitumor activity as a monotherapy in patients with pretreated ad
35 lta (PI3Kdelta) inhibitor that has promising activity as a monotherapy in refractory indolent lymphom
36 tility of a bivalent pharmacophore with dual activity as a mu/delta opioid agonist and NK1R antagonis
37 or-focused approach offers an account of LIP activity as a multiplexed amalgam of sensory, cognitive,
38 results provide additional evidence for TSSP activity as a novel mechanism promoting autoreactive CD4
40 nti-MIF strategy that targets this enzymatic activity as a potential future antibacterial therapeutic
41 Ser1928, suggesting enhanced protein kinase activity as a potential link between increased KATP curr
42 ic validation for inhibition of LRRK2 kinase activity as a potential means of affecting disease progr
44 n localizing thrombin via its antithrombin-I activity as a potentially self-limiting hemostatic mecha
45 These findings identify enhancement of NAMPT activity as a promising new therapeutic strategy to prot
48 alpha-mediated NF-kappaB luciferase promoter activity as a result of lowered inhibitory IkappaBalpha
49 identified late-latency, long-lasting neural activity as a robust correlate of conscious perception.
50 y various microorganisms point to biological activity as a significant source of ROS in the absence o
51 ome T-cell ALLs (T-ALLs), predicting in vivo activity as a single agent and in combination with dexam
54 enesis of AD and the modulation of microglia activity as a therapeutic modality will be discussed.
55 rrant activation of beta-catenin through its activity as a transcription factor has been observed in
57 est important biological implications on p53 activity as a transcriptional regulator of cellular resp
58 e its essential role in Hh signaling and its activity as a tumor suppressor, Ptch1 remains largely un
59 T. gondii inhibitor of STAT1 transcriptional activity) as a critical molecular switch that is secrete
61 indings suggest that weakened humoral immune activity, as a consequence of persistent chronic infecti
64 ofound effect on the microbial diversity and activity, as a result of diffusion limitation and thus s
65 h the RTX domain showed similar neutralizing activity as ACT-immunized mice, indicating that this dom
66 that RAGE function is dependent on secretase activity as ADAM10 and gamma-secretase inhibitors blocke
67 ponsible for weekly variation in antioxidant activity, as addition of these agents inhibited DPPH sca
68 sed cyclopentapeptides (cRGD) with nanomolar activity as alphavbeta3/alphavbeta5 integrin antagonists
69 -protein interactions, rather than catalytic activities, as an approach for producing effective antit
71 d human LCAT protein with enhanced enzymatic activity as an immunogen, we generated fully human monoc
72 rlotinib-mediated inhibition of AAK1 and GAK activity as an important mechanism of antiviral action.
73 e that was detailed in the article "Physical Activity as an Index of Heart Attack Risk in College Alu
74 factors: poor SK1/2 selectivity, additional activity as an inducer of SK1-degradation, and off-targe
75 o optical assays for the determination of LE activity as an inflammatory biomarker and proxy for the
76 shion and highlight the importance of neural activity as an intervening factor between molecular and
77 ate (which is known to affect CB glomus cell activity) as an agonist for the most highly abundant G p
79 the novel compound presented high prebiotic activities as ascertained in the presence of lactic acid
81 was associated with increased daily physical activity as assessed by actigraphy (average activity [SD
82 d long-term preservation of miRNA functional activity, as assessed by monitoring the expression of 2
84 sociated with significantly increased sexual activity, as assessed by the Psychosexual Daily Question
85 24 levels showed an association with disease activity, as assessed by the urticaria activity score an
87 Considering only 32 scans of the highest activity as categorized by a visual scoring strategy, we
88 f FAD-causing mutant PS to the same level of activity as channels in control cells stimulated by sign
89 of cortisol and CLO mostly showed a similar activity as CLO alone on physiological and transcription
90 f new imidazolium salts, which show superior activity as cocatalysts for the reaction, i.e., CO is se
91 heir redox properties and improved catalytic activities as compared to the conventional reference cat
92 All nucleoapzymes reveal enhanced catalytic activities as compared to the separated DNAzyme/aptamer
93 h 100% selectivity and 9-fold increased mass activity as compared to a more traditional aluminosilica
94 ificantly increased kynurenine level and IDO activity as compared to healthy controls and mastocytosi
97 kind and has displayed superior anti-cancer activity as compared to the current first line drug gemc
99 r, the long 3'UTR conferred lower luciferase activity as compared with the short form, indicating tra
100 ls were found to exhibit a higher phagocytic activity as compared with the subsequently recruited non
102 p with S. mutans expressing collagen binding activity, as compared to the group without that finding.
104 cellular growth, architecture and metabolic activities as confirmed by their viability, scanning ele
105 capability and exerted measurable anticancer activities as confirmed with percent tumor necrosis hist
106 it and pure isolates showed antiinflammatory activity as confirmed by in vitro cyclooxygenase enzymes
109 rbal agent, consistently induced readthrough activity as demonstrated by enhanced CFTR expression and
111 wing a reduction in extracellular proteinase activity as demonstrated by the reduction, or abolition,
112 activating Gp1 mGluR elevates neural network activity, as demonstrated by increased spontaneous spike
113 s was independent of its protease inhibitory activity, as demonstrated by the use of reactive-center-
114 of the oxetane graft enhances stability and activity, as demonstrated for a range of biologically re
115 Moreover, we could show that the monocyte activity as depicted by S100A9 activity in the primary t
116 roteins with the following sequential enzyme activities as determined by mass spectrometry and one- a
118 Our stimulation selectively enhanced spindle activity as determined by increased sigma activity after
121 cessibility of the pyrimidine tract and IRES activity, as determined in both in vitro and in vivo sys
124 eliable methods are needed to determine MGMT activity as DNA methylation, the current standard, does
126 w is organized around four themes: (i) human activities as drivers of change; (ii) variability of the
128 d increase in alpha and low beta oscillatory activity as early as 80 ms after T1, indicating that the
129 te period post defecation, with most E. coli activity (as either die-off or growth) occurring at low
131 decreased intracellular ATP levels and AMPK activity, as evaluated by its phosphorylation at threoni
132 e TS cells displayed much greater metastatic activity as evidenced by an increased invasion rate, ext
133 enhanced rictor levels and increased mTORC2 activity as evidenced by increased formation of mTORC2 a
134 duction in CVB3-induced NLRP3 expression and activity as evidenced by lower ASC (apoptosis-associated
135 d also modest radical-inhibiting antioxidant activity, as evidenced by an assay based on phenolic hyd
137 eel extracts have an effective antimicrobial activity, as evidenced by the inhibitory effect on the b
138 be used in live cells to measure transporter activity, as excretion of BR depends on ABC and SLC tran
139 Purified CshA exhibits typical RNA helicase activities, as exemplified by RNA-dependent ATPase activ
140 ure does not reflect an increase in cellular activity as expected.SIGNIFICANCE STATEMENT Desensitizat
141 balance task, not to the cumulative afferent activity, as expected for vestibulospinal reflex loops.
143 that Foxa3 is required for HSC repopulating activity, as Foxa3(-/-) HSC fails to repopulate ablated
144 phenotypes depend on distinct p53 downstream activities as genetic ablation of the pro-apoptotic gene
146 serve that the relative decrease in platelet activity as hematocrit falls shows a similar profile for
147 Both Au(III)@1 and Au(I)@1 display high activity as heterogeneous catalyst for the hydroalkoxyla
148 of up to 17 mm on no-PSF no-TOF PET, (124)I activities as high as 170 MBq may be warranted to obtain
149 eficient B cells was dependent on Btk kinase activity, as ibrutinib treatment restored pS6 to wild-ty
150 RK1 degradation is strictly dependent on its activity, as inactive SnRK1 variants are aberrantly stab
151 the Mayo endoscopy score (P = 0.01), disease activity as indicated by the total Mayo score (P = 0.001
152 skipping of MKK7 exon 2 enhances JNK pathway activity, as indicated by c-Jun phosphorylation and up-r
153 silencing significantly rescued F508del-CFTR activity, as indicated by enhanced anion transport throu
155 ions can alter behavior by influencing brain activity as individuals weigh uncertain gains against un
159 est that this occurs through basal NF-kappaB activity as knockdown of the NF-kappaB subunit RelA supp
160 e regeneration through its H3K27 demethylase activity, as loss of demethylase activity either by chem
163 erlying DNA sequences and divergent enhancer activity as marked by histone 3 containing the acetylate
164 mice had similar respiratory and glycolytic activities as measured with Seahorse XF24 analyzer in me
165 tea incorporation increased the antioxidant activity as measured by chemical assays, had little effe
166 n the activity per body mass and the minimum activity as measured by the factor of variation were sub
167 ed in 47 (40.2%) and correlated with disease activity as measured by total BPDAI (r = 0.918; P = .06)
169 neurons and glial cells and showed neuronal activity, as measured by rhythmic waves of calcium trans
171 prevention of NET formation and proteolytic activity as modelled in NE(-/-) mice prevent collateral
174 hibitors is currently focussed on evaluating activity as monotherapy and as potentiators of chemother
177 se naked HER2 antibodies provide only modest activity as monotherapy, the toxin-carrying antibody tra
178 ntification of multitargeted prototypes with activities as MT-stabilizing agents and/or inhibitors of
179 compounds have been studied because of their activity as mutagens or drugs, but little is known regar
182 ies that enhance PP2A and inhibit proteasome activity as novel therapeutic strategies for asthma.
184 ace of the substrate for efficient catalytic activity, as only LPMOs appended to CBMs bound tightly t
185 rate as receptors which directly regulate AC activity as opposed and in addition to the indirect regu
186 ates functionally distinct ceramide synthase activities as part of a broader sphingolipid homeostatic
187 ion and determine distinctive ubiquitination activities as part of a response mechanism ensuring accu
188 itor in vitro that uses its processive motor activity as part of a feedback loop to further promote m
189 ncorporation of increased levels of physical activity as part of the commute to work could reduce obe
191 Learning was associated with a change in V1 activity, as part of a temporo-occipital and basal gangl
192 Recognition memory was associated with V1 activity, as part of a temporo-occipital network involvi
194 olecular determinants associated with low NA activity as potential markers of aerosol transmission.
195 oE and implicated protease- and IL-1-related activities as putative central pathways in disease patho
197 ptimizing the amount of injected peptide and activity, as recent studies have shown different degrees
198 tors displayed different levels of proneural activity as reflected by the number and functionality of
199 ggests that the changed spontaneous neuronal activity, as reflected by the fALFF, in these regions ma
201 FH showed a strong C3bBb decay-accelerating activity, as reported previously, and also exerted an ap
202 he requirements in P for stimulation of RdRP activity as residues 11 to 50 of P and formally demonstr
204 unctional relevance of reduced BRAG1 Arf-GEF activity as seen in the XLID-associated human mutations.
205 repetitive structures exhibit hTSP-1 binding activity as shown by ELISA and surface plasmon resonance
207 re associated with increased transcriptional activity, as shown by HDAC inhibitor-induced chromatin r
208 and mesophyll cells, but did not possess AO activity, as shown by heterologous expression of OsORAP1
209 ulting in suppression of p53 transcriptional activity, as shown by p53-responsive element-driven luci
210 80 and 800 nm, and exhibit reversible redox activity as single particles, as monolayer films, and in
211 pite there being little evidence of clinical activity as single-agent therapies, we show that dual bl
213 aphy in humans to record changes in neuronal activity as subthreshold rhythmic stimuli gradually beca
217 graphy and estimated desaturase and elongase activities as the ratio of product fatty acids to precur
218 is gap by explicitly interpreting population activity as the aggregate response of many single neuron
220 is of the RNA-seq data identifies cell cycle activity as the major source of transcriptomic variation
221 ults establish the Golgi-associated V-ATPase activity as the molecular link between actin and the Gol
222 ntify a reduction in cardiac parasympathetic activity as the primary mechanism underlying the elevate
223 at expresses the spatiotemporal fluorescence activity as the product of a spatial matrix that encodes
224 istent with a mechanism for the emergence of activity as the product of many independent contribution
225 reatment may not phenocopy the loss of eIF4A activity, as these drugs actually increase the affinity
229 tively modulated by tonic, constitutive GPCR activity as TRPM3 responses can be potentiated by GPCR i
230 ng term, and such specific types of physical activity as walking or bicycling and work or occupationa
231 , which provides clear evidence for butchery activities as well as four bones having been used for re
232 , detachment from others, and disinterest in activities as well as moderately strong links among irri
233 r alpha-amylase, endoxylanase, and peptidase activities as well as signs of (incipient) protein, beta
234 nning of 2016, including reported biological activities as well as the isolation of new members of th
235 tions are discussed in relation to these two activities as well as their influence on base selectivit
236 anodrugs that display enhanced antibacterial activities, as well as aggregation-induced emission (AIE
237 derstanding of tightly regulated transporter activities, as well as conceiving the interplay of regul
238 ate-to-vigorous leisure, household and total activities, as well as for meeting PA recommendations.
239 ate previously underreported island building activities, as well as to assess resulting in-water turb
240 finger abduction force and electromyographic activity as well as a hand dexterity task were measured
241 layed impaired transcription and replication activity as well as a lack of an association with certai
244 resynaptic dysfunction and restores neuronal activity as well as dendritic spine levels in vitro.
245 , demonstrating that features of transporter activity as well as DNA content are determinants of SP/N
247 ized by higher chromatin and transcriptional activity as well as enriched TF and ncRNA binding across
249 expression, in vitro migratory and invasive activity as well as in vivo growth of tumor cell xenogra
250 anism was dependent on both constitutive ERK activity as well as inhibition of the stress kinase p38.
253 protease family and required Ubp3 catalytic activity as well as its interaction with the cofactor Br
256 postsynaptic gain in primary auditory cortex activity as well as modulation of feedforward, but not f
257 mplex provides a basis for understanding ORC activity as well as molecular defects observed in Meier-
260 rage and domestic cooking on the antioxidant activity as well as on the aromatic amino acid and carot
263 ometry were employed to directly measure Akt activity as well as proteolytic activity in individual f
266 ant light conditions rescues courtship vocal activity as well as the duration of single calls, and (3
267 to the IL-6Ralpha promoter and regulates its activity as well as the expression of this receptor.
268 sulting in the highest yield and antioxidant activity as well as the highest contents of punicalagin
270 ough the manipulation of auxin and cytokinin activity as well as through the activation of energy sig
271 omplexes that are important to inhibit toxin activity as well as to release the active toxin remain e
273 health-promoting cities, benefits (physical activity) as well as hazards (air pollution) should be e
274 selectively enhanced 5alphaR expression and activity, as well as AP levels, in the prefrontal cortex
275 icient for plus-end binding and depolymerase activity, as well as by the identification of an alpha-t
277 of osteoclastic markers and bone resorption activity, as well as decreased expression of many inflam
278 revisiting the mechanism of a-MoSx catalytic activity, as well as explaining some of its special prop
279 y age, sex, mechanism of injury, and related activity, as well as factors associated with short-term
280 ase duration, treatment history, and disease activity, as well as impact on health-related quality of
281 perceptual and semantic influences on neural activity, as well as in identifying stimulus-driven, "bo
283 tor dasatinib, which antagonizes TNK2 kinase activity, as well as novel TNK2 inhibitors, XMD8-87 and
285 Compositional changes related to microbial activity, as well as proteolytic and lipolytic phenomena
286 ficiency led to increased FXIIIA amounts and activity, as well as reduced bleeding times in homeostat
287 m context-dependent modulation of excitatory activity, as well as regulate experience-dependent plast
288 nputs effectively timed the principal neuron activity, as well as regulated distinct CA1 interneuron
289 Ps can serve as endogenous modulators of IDE activity, as well as regulators of its intracellular spa
290 In vivo microelectrode recordings of basal activity, as well as responses to afferent and efferent
291 and PDB for fragments showing PDE inhibitory activity, as well as SureChEMBL for recent PDE related p
292 cid, that activates TRPV1 and whose pruritic activity, as well as that of histamine, occurs through t
293 AR1 binding behaviors related to its editing activity, as well as the antagonizing effect of RBP bind
295 degree of intratumoral heterogeneity in EGFR activity, as well as the pharmacodynamic effect of a rad
298 d that the Arkadia W972A mutant has the same activity as wild-type (WT) Arkadia in enhancing TGF-beta
300 in part dependent upon beta-catenin pathway activity, as YAP/TAZ downregulation induced by SCD1 bloc
WebLSDに未収録の専門用語(用法)は "新規対訳" から投稿できます。