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1 e marrow absorbed dose per unit administered activity of (131)I, after THW and rhTSH, was 232 and 62
5 d TC treated with (131)I by an empiric fixed activity of 3.7 GBq at Gustave Roussy (GR, n = 231) or b
10 res of various agents to enhance the overall activity of a cocktail of multiple enzymes and achieve o
11 s using sparse motor networks, we imaged the activity of a complete ensemble of wing control muscles
12 lved alternative mechanisms to fine-tune the activity of a cysteine protease dubbed RD21 (RESPONSIVE
15 all polysaccharide, requires the cooperative activity of a large repertoire of microbial enzymes.
19 ing lines are likely due to the compensatory activity of a TAG-synthesizing enzyme with specificity f
23 In this study, we evaluated the antileukemia activity of adoptively transferred polyclonal cancer ant
24 2+) channel that contributes to the rhythmic activity of adult DA neurons in the substantia nigra reg
25 ts suggest that the phospholipid transporter activity of ALA1/ALA2 may be necessary for the formation
28 ows efficient measurement of transcriptional activity of alpha-SYN in its native epigenetic landscape
30 ingle nonsynonymous mutations for hydrolysis activity of an amidase expressed in E. coli with three d
31 Ammonium oxidation occurred solely by the activity of anammox bacteria identified as Candidatus Sc
35 t monomers but not trimers, with some higher activity of anti-V2 MAbs than of anti-V3 and anti-CD4bs
36 of vivax invasion assays, binding-inhibitory activity of antibodies has been reported to be associate
40 the local environment, and the structure and activity of associated microbial communities were examin
41 This interaction allows the deubiquitinase activity of ataxin 3 to protect beclin 1 from proteasome
42 a phospho-switch that regulates the cellular activity of ATG4B to control LC3 processing.Upon autopha
44 eriments have shown a heterogeneous promoter activity of autoinducer synthase genes, suggesting that
46 P G P G G) was developed for quantifying the activities of bacterial enzymes using a highly sensitive
48 the nucleus is regulated by the antagonistic activities of both a peptide-encoded N-terminal nuclear
50 supplementary role for C5aR, and no apparent activity of C5L2 in infection-induced peritoneal fibrosi
51 Rho-GTPase activity were attributable to the activity of calcium-sensing receptors (CaSRs), which app
53 macrophages results in lower expression and activity of cathepsin K compared with resting unpolarize
54 licable in screening and characterisation of activity of CAZymes, such as fungal enzymes for plant li
55 NCE The greater ex vivo antiviral inhibitory activity of CD8(+) T cells from elite controllers than f
56 ce-breaker," which enhances the bactericidal activity of Ceftriaxone/Cefotaxime against highly pathog
57 near models were used to predict the spiking activity of cells in both areas as a function of differe
59 t effect did not require the known catalytic activity of CheR, but did involve a binding interaction
62 aeruginosa and A. baumannii and enhanced the activity of colistin in vivo against colistin-resistant
65 fold and 11-fold enhancements in the oxidase activity of Cu- and Fe-bound HCO mimics, respectively, a
68 ined functional impairment and impairment in activities of daily living (ADL) (defined as severe or m
70 who report moderate to severe limitations in activities of daily living (clinical functional score >/
73 ognitive domains, psychosocial function, and activities of daily living were pooled separately for mi
74 d, but that women's functional capacities in activities of daily living, cognition, and physical perf
76 ce interval [CI], -175 to -43), London Chest Activity of Daily Living Questionnaire = 18 (95% CI, 7-3
82 ive immunity, addressed here, integrates the activities of distinct T-cell subsets and by definition
83 -dependent autophagy during infection by the activity of distinct viral proteins, thereby limiting it
84 match correction depends on the proofreading activity of DNA polymerase-delta, although the repair pr
85 s unable to fully recapitulate the oncogenic activity of DNAJB1-PRKACA, implying that FL-HCC does not
91 own to be absolutely necessary for efficient activity of eEF-2K, and Ca(2+) is shown to enhance the a
95 ake caused an increase in the expression and activity of ENaC which resulted in the steady state depo
96 armacodynamic profiles, safety, and clinical activity of enasidenib in patients with mutant-IDH2 adva
97 ether PAP thereby affects the expression and activity of enzymes involved in phospholipid synthesis.
100 mitochondrial iron levels, a decrease in the activities of Fe-S cluster enzymes, a decrease in respir
102 SOs in the liver as evidenced by the loss of activity of GalNAc conjugated and unconjugated ASOs in A
103 Taken together, the enhanced proteolytic activity of Gly1629Glu can be readily explained by an in
105 udy was to evaluate the potential inhibitory activity of guarana extracts, after digestion in vitro,
106 reduced survival as well as the numbers and activity of H1N1- and H3N2-specific memory CD8(+) T cell
107 ontoxic and can neutralize the anticoagulant activity of heparins and the prothrombotic activity of p
108 eraction of this NLR pair thus suggests that activity of heteromeric NLR signaling complexes depends
109 ancing the stabilization and transcriptional activity of HIF-1alpha and strengthening adaptive respon
112 NA binding but inhibited the transcriptional activity of human HSF1, interfering with the assembly of
114 ype K(+) current (IA ) influences the firing activity of hypothalamic magnocellular neurosecretory ne
118 ein target for the teratogenic and antitumor activities of immunomodulatory drugs such as thalidomide
122 ate, characterize and evaluate the prebiotic activity of inulin and FOS from S. rebaudiana stems.
123 ith a time course that mimics the endogenous activity of its target is capable of altering the target
124 echanistically, we showed that the enzymatic activity of JMJD6 was required for a subset of JMJD6-reg
125 complex coupled with the succinyltransferase activity of KAT2A is instrumental in histone succinylati
126 ro, this modification completely ablated the activity of LLO, and this inhibitory effect was fully re
128 ether analogs of LPC The data show that the activities of LPEAT1 and LPEAT2 are, in a complementary
130 rate that the maximum actin-activated ATPase activity of M2beta-S1 is slowed more than 4-fold in the
131 dy, we find that loss of Pdcd4 increases the activity of mammalian target of rapamycin complex 2 (mTO
133 h, affected the accumulation and tolerogenic activity of MDSCs in tumors, and inhibited the expressio
134 op of 7SK and inhibits the methyltransferase activity of MEPCE through a C-terminal MEPCE interaction
137 s a retrospective log analysis of the online activity of millions of web searchers seeking health-rel
138 L-1 appears to inhibit the electron transfer activity of mitoNEET by forming a unique complex with mi
141 ection initiation pathway where the nuclease activity of MRN apparently directly cleaves the 5' stran
144 ponses most often arise from the coordinated activity of multiple SCPs, we developed a dynamic enrich
146 e QC strains consistent with the spectrum of activity of nafithromycin were tested: Staphylococcus au
147 which mimic the paracrine and biointerfacing activities of natural stem cells in therapeutic cardiac
150 g membrane, which depended on Ca(2+) and the activity of neutral sphingomyelinase but not clathrin-co
151 ediated attack, improving phagocytic killing activity of neutrophils, and preventing bacterial adhere
152 ly, the presence of ApN markedly reduced the activity of NF-kappaB, a key player in muscle inflammati
154 ceptor currents by reducing the constitutive activities of odorant receptors, inhibiting the basal sp
156 implications of these findings on the basal activity of opsins and the associated dark noise in the
158 the OER; however, the origin of the advanced activity of oxygen electrocatalysts is still somewhat co
159 mmetry on the plasma membrane depends on the activities of P4-ATPases, and disruption of PS distribut
161 ovel mechanism by which MALAT1 regulates the activity of p53 through the lncRNA-protein interaction.
163 hat they are not essential for the catalytic activity of Pah1 and its physiological functions (e.g. t
164 is work also demonstrated that the catalytic activity of Pah1 is required but is not sufficient for i
165 40S particles, suggesting that the enzymatic activity of PARN is necessary for the release of 18S-E f
166 rescuing cell division when the biochemical activity of PBP 2B is perturbed evolved prior to the cli
168 ion, inhibits the transcriptional activation activity of PHYTOCHROME INTERACTING FACTOR 4 (PIF4), a k
170 JUNV's ability to antagonize the antiviral activity of PKR appears to be complete, as silencing of
171 of exogenous HCT enabled us to show that the activity of plant-encoded enzymes (histone deacetylases)
172 typically derived from the lipid-hydrolyzing activity of PLDalpha1, is a molecular target of RGS1.
176 quently used to explain the high antioxidant activity of polyphenolic compounds leading to the format
177 n of ankyrin isoforms relies on differential activity of positive and negative regulators of alternat
181 bulb (MOB), inhibitory circuits regulate the activity of principal cells precisely to drive olfactory
182 PtdIns3K) correlated with the macropinocytic activity of pro- and anti-inflammatory macrophages.
184 rsinia-induced apoptosis requires the kinase activity of receptor-interacting protein kinase 1 (RIPK1
185 es also contributes to sustain the increased activity of respiratory metabolism to fuel plant defence
186 we enhanced the neurotransmitter transporter activity of rigid nucleosides while reducing A3AR affini
187 model genome wide and profile the enzymatic activity of RNA polymerase across various loci and follo
191 cted ex vivo with MAV-1 had no difference in activities of secreted MMP2 and MMP9 from mock cells.
194 Our results show that the combination of activity of several key kinases can predict the occurren
198 ) ratio and the NAD(+)-dependent deacetylase activity of sirtuin 3 to inhibit superoxide dismutase 2
201 clonal antibodies that act by inhibiting the activity of specific proteins that drive tumor growth.
202 ate that mTOR can, in parallel, regulate the activity of stress transcription factors, including sign
204 BCNT), is essential for the histone exchange activity of SWR, whereas an acidic region at the N-termi
206 alpha was higher, whereas the expression and activity of TACE were lower, in wild-type DCs (wtDCs) th
209 her, these findings suggest that biochemical activities of the cell are spatially organized into an a
210 ported to stimulate the helicase and primase activities of the complex in the presence of ICP8, an HS
212 nce of the CDNs is followed by the catalytic activities of the constituents and by complementary quan
214 used mouse liver CRMs involved in regulatory activities of the hepatic TR, NR1H4 (FXR; farnesoid X re
218 as quantified by measuring chymotrypsin-like activity of the 26S proteasome and messenger RNA express
220 role of PKA-dependent phosphorylation on the activity of the actin-based Rab27a/melanophilin/myosin V
221 nly increase the number but also enhance the activity of the active sites in MOR compared with larger
224 Here we report the multistage antiplasmodial activity of the aspartic protease inhibitor hydroxyl-eth
225 electrodeposited within the hydrogel and the activity of the bi-enzymatic system was analyzed chronoa
226 orous holey nanostructure and high catalytic activity of the cathode, the as-prepared Li-CO2 batterie
228 Our findings suggest that AMPK regulates the activity of the chromatin modifying COMPASS complex (com
231 s deneddylation, facilitated by the protease activity of the CSN (COP9 signalosome), are required to
232 of the neddylation E3 complex, regulates the activity of the cullin-RING-ligase type of ubiquitinatio
234 apacity and the alpha-glucosidase inhibitory activity of the duodenal extract correlated with the amo
235 cts, at least in part, through promoting the activity of the E3 ubiquitin ligase UBR2 towards L1-ORF1
236 ibody fragments (Fabs) that can modulate the activity of the enzyme isocitrate dehydrogenase 1 (IDH1)
237 was formed quantitatively, and the catalytic activity of the enzyme was not impaired by exposure to r
239 found that: (1) perturbations increased EMG activity of the gluteus medius and postural control musc
245 n cytokine-stimulated NK cells increases the activity of the metalloprotease TNF-alpha-converting enz
247 ting a mechanism through which the oncogenic activity of the mutant receptor is tempered by the activ
248 hway, NLRC3 interferes with the assembly and activity of the NALP3 inflammasome complex by competing
253 hat, in BL, HSP90 inhibition compromises the activity of the pivotal B-cell antigen receptor (BCR)-pr
254 es an S188I mutation increases the enzymatic activity of the protein and its ability to restrict HIV-
258 hat cytoplasmic YAP positively regulated the activity of the small GTPase CDC42, deletion of which ca
259 Here, we quantify the extent to which the activity of the supermassive black hole at the center of
261 d by the absence of Vpr, the transcriptional activity of the viral long terminal repeat (LTR) from Vp
263 s strongly controlled by the salinity (water activity) of the reacting fluid and demonstrate that the
264 for antibacterial T6SS substrates, the toxic activities of these effectors are neutralized by adjacen
265 heir tetrapeptidic backbones, the anticancer activities of these precursors largely match their self-
267 Recent studies have demonstrated that the activities of these proteins have a variety of spatiotem
269 23 and interleukin-12 and thereby blocks the activity of these cytokines, inhibiting interleukin-23-d
273 ng neurons to the theta wave, and the firing activity of theta-driving neurons shares a substantial a
274 results show that information flows from the activity of theta-driving neurons to the theta wave, and
275 to screen the antibacterial and antioxidant activity of thirty nine honey samples from Finland, Swed
277 T allele variation at rs604723 increased the activity of this fragment by promoting serum response tr
279 dding yeast a large-scale measurement of the activity of thousands of designed promoters at six diffe
280 we investigate the spectrum of antibacterial activity of three phenylthiazole-substituted aminoguanid
281 ies are warranted to explore the anti-tumour activity of tivozanib in combinatorial approaches in GBM
283 RS mutation could potentiate the angiostatic activities of TrpRS by enhancing its interaction with va
284 pecially of quinolinic acid-indicated a high activity of tryptophan degradation in patients with acti
285 wed that MAV-1 infection increases enzymatic activity of two key MMPs known to be secreted and activa
286 In contrast, C1P did not affect transport activity of two other major efflux transporters, multidr
287 of ex vivo (in yeast), in vitro, and in vivo activities of type-2 diacylglycerol acyltransferases in
288 analysis reveals that the intrinsically low activity of Ubc15 largely results from the presence of a
289 evealed that UbVs specifically inhibited the activity of UBE4B or phosphorylated CBL by blocking the
291 ule-1 (ICAM-1) and diminishing the enzymatic activity of urokinase-type plasminogen activator (uPA) a
292 hat the onset and termination of the calling activity of users follows a yearly dynamics, varying acr
293 NAs can be a complex process governed by the activities of various 3'-end polymerases and exonuclease
294 this mAb can enhance the in vitro cytotoxic activity of venetoclcax for CLL cells with high-level ex
295 phrenia, may arise in part from dysregulated activity of ventral tegmental area dopaminergic (TH(VTA)
298 vation-induced cytidine deaminase (AID), the activity of which leads to DNA double-strand breaks (DSB
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