ライフサイエンスコーパス: acute

1 3)) and acrolein (28 mug m(-3)) exceeded the acute 1-h exposure REL for the highest emitting vaporize

2 regional cerebral microvascular responses to acute (2 h) and prolonged (10 h) poikilocapnic normobari

3 te, antioxidant enzyme activity) toxicity in acute (96 h) copper and cadmium exposures, using the sha

4 This is exemplified in the assessment of acute abdominal pain, in which a physician's palpation d

5 asal insulin to evaluate its efficacy during acute abstinence from smoking.

6 s suggest that in these inflammatory models, acute administration of peripherally restricted NaV1.7 i

7 erived from alcohol users and after in vitro acute alcohol treatment of human MDDCs.

8 The pathology of ovalbumin-induced acute allergic airway inflammation after adoptive transf

9 in TH2 lymphocytes and on the development of acute allergic airway inflammation.

10 wo (3%) in the high-dose group; only one (an acute allergic skin reaction in the low-dose group) was

11 Both acute and chronic ambient temperature extremes may affec

12 med cell death that is pathogenic to several acute and chronic diseases and executed via oxygenation

13 The hepatitis B virus (HBV) causes acute and chronic liver infection, which may lead to liv

14 ICL), may mediate survival of Mtb during the acute and chronic phases of infection in mice through ph

15 mic-pituitary-adrenal axis responses to both acute and chronic stress and were protected against weig

16 rine, autonomic, and behavioral responses to acute and chronic stress.

17 flammatory effects of BHB on rats exposed to acute and chronic stress.

18 gated sodium channel NaV 1.7 is required for acute and inflammatory pain in mice and humans but its s

19 nnel subtype NaV 1.7 is required for sensing acute and inflammatory somatic pain in mice and humans b

20 f C. difficile incidence and risk factors in acute and long-term care.

21 Acute and post-cART levels of viremia were similar, howe

22 In pediatric patients with acute appendicitis undergoing appendectomy, SDD is not a

23 of surgical versus conservative treatment of acute appendicitis.

24 entially represent venous engorgement and/or acute blood products within the spinal cord.

25 n rate among infants with a first episode of acute bronchiolitis.

26 of HVBP were assessed for matched samples of acute care hospitals (the number of hospitals included i

27 tensin II receptor type 1 (AT1R), stimulates acute catecholamine secretion through coupling with the

28 associated with antibody mediated rejection, acute cellular rejection, and bronchiolitis obliterans s

29 es (DSA), antibody-mediated rejection (AMR), acute cellular rejection, and graft status.

30 nested in the Antihypertensive Treatment of Acute Cerebral Hemorrhage II (ATACH-II) randomized clini

31 Of 3096 acute cerebral or peripheral vascular events, 748 (24.2%

32 16) were significantly increased in MPs from acute CF patients.

33 ing MPs from 33 individuals: 11 with T2D and acute CF, 11 T2D patients with equivalent neuropathy and

34 ness finding (84%), and neuroimaging without acute changes (82%).

35 Acute changes in LA pressure after MitraClip procedure a

36 al infarctions (MIs; nonfatal and fatal) and acute CHD deaths.

37 Acute CHD events included myocardial infarctions (MIs; n

38 GC degeneration or axonal regeneration after acute CNS injury.SIGNIFICANCE STATEMENT The roles of mic

39 ncreased locomotor activation in response to acute cocaine administration and an altered locomotor se

40 in CD in the abstinence/saline condition vs acute cocaine and HC.

41 rmogenic metabolism in adipose depots during acute cold exposure.

42 Conversely, colectomy for severe acute colitis was associated with decreased risk of IRA

43 Acute consumption (1.34 ng/bee) impaired locomotion, cau

44 own-regulated during inflammation induced by acute contact hypersensitivity (CHS).

45 Acute conversion to sinus rhythm was observed in 2 patie

46 sessed the incidence of AKI in patients with acute coronary syndrome (ACS) enrolled in the MATRIX-Acc

47 Of the 310 subjects, 138 had an acute coronary syndrome (ACS), 101 of whom underwent des

48 ation between WBC and MACE was consistent in acute coronary syndrome and non-acute coronary syndrome

49 I concentrations in patients with suspected acute coronary syndrome in which the diagnosis was adjud

50 of short-term mortality and complications in acute coronary syndrome patients treated with extracorpo

51 onsistent in acute coronary syndrome and non-acute coronary syndrome presentations (interaction P=0.1

52 Among patients with stable angina or an acute coronary syndrome, an iFR-guided revascularization

53 n for heart failure, and hospitalization for acute coronary syndrome, and the incidence of acute panc

54 In stabilized individuals within 10 days of acute coronary syndrome, combination therapy seemed to b

55 oronary artery disease or presenting with an acute coronary syndrome, including ST-segment-elevation

56 statin therapy in patients stabilized after acute coronary syndrome.

57 The total number of PCIs in patients with no acute coronary syndrome/no prior coronary artery bypass

58 Is performed in New York in patients without acute coronary syndromes or previous coronary artery byp

59 Acute corticosterone exposure accelerated metamorphosis

60 y practices in England among 401 adults with acute cough and at least 1 lower respiratory tract sympt

61 Primary EN-DCR in acute dacryocystitis with lacrimal sac abscess results i

62 We tested the effect of acute DCS (10-20 V m(-1) for 3-5 s) on synaptic dynamics

63 ced by DLX3-null keratinocytes, we performed acute deletion of DLX3 in adult epidermis using a tamoxi

64 ll molecule inhibition, genetic deletion, or acute depletion of MELK did not significantly affect cel

65 Among patients 16 years or older with an acute, displaced, extra-articular fracture of the distal

66 , neuromyelitis optica spectrum disorder and acute disseminated encephalomyelitis) and from non-demye

67 These results suggest that the acute effects of cannabis on anxiety in males are mediat

68 In this study, the acute effects of high-density ischemia were investigated

69 ty every year, which is comparable to recent acute epidemics, including the 2014 Ebola and 2015 Zika

70 the various MTTT protocols in patients with acute erythema migrans ranged from 36% (95% confidence i

71 n equivalent or higher nicotine delivery, an acute exposure to e-cigarette aerosol had a reduced impa

72 bial-resistant infection among patients with acute febrile illness in India.

73 emble the substrate of human eroded plaques, acute flow perturbation promoted downstream endothelial

74 t, with monthly notification of new cases of acute FPIES in infants aged less than 24 months by 1400

75 aditional therapy to resolve the symptoms of acute FPIES.

76 us are important pathogens that cause severe acute gastroenteritis in both humans and animals.

77 available tool for detecting the location of acute gastrointestinal bleeding.

78 corticosteroids reduce pain in patients with acute gout.

79 Acute graft-versus-host disease (aGVHD) continues to be

80 matched HCT, myeloablative conditioning, and acute graft-versus-host disease (P values < .01).

81 nuated clinical symptoms in animal models of acute graft-versus-host disease and multiple sclerosis.

82 Grade II to IV acute graft-versus-host disease related to steroid treat

83 Patients who developed acute GVHD despite maraviroc prophylaxis showed increase

84 wever, its safety and efficacy in preventing acute GVHD in settings of heightened clinical risk that

85 edictive of subsequent development of severe acute GVHD in this study.

86 regimens without interferon for treatment of acute HCV in HIV-1 infected individuals (SWIFT-C) is an

87 fosbuvir plus ribavirin for the treatment of acute HCV infection in participants with chronic human i

88 gestion is associated with worse outcomes in acute heart failure (AHF).

89 ohort of patients discharged from a previous acute heart failure admission.

90 r study measured PENK in 1,908 patients with acute HF (1,186 male; mean age 75.66 +/- 11.74 years).

91 re) clinical cohort study, 496 patients with acute HF were enrolled in 14 hospitals in the Netherland

92 d to determine whether ART initiation during acute HIV infection would attenuate changes in these bio

93 0 and 2010, resulting in rising pressures on acute hospital services, and an increasing need for end-

94 n 422,730 surgical patients from 300 general acute hospitals in 9 countries, with survey data from 26

95 c hypoxia (MCH) mouse model and a new severe acute hypoxia (SAH) mouse model of DWMI activates the in

96 rial superoxide release, was detected during acute hypoxia in wild-type but not Cox4i2(-/-) PASMCs.

97 ether intensive BP lowering in patients with acute ICH is safe and effective in improving clinical ou

98 Rs) >/=3;efficacy outcome), in patients with acute ICH randomised to either intensive BP-lowering or

99 ligible studies including 4360 patients with acute ICH were pooled in meta-analysis.

100 All 10 exposed individuals developed an acute illness clinically compatible with trichinellosis,

101 lity following inpatient hospitalization for acute illness.

102 Using acute inactivation approaches and live-cell imaging in D

103 cs of memory-effector T cells such that with acute inactivation of the gene encoding FOXO1, T cells r

104 Linear regression of acute individual measures with contractile function in c

105 c Smad3 loss were not a result of effects on acute infarct size but were associated with unrestrained

106 ient to induce spreading depolarizations and acute infarction in adjacent cortex.

107 sponses in the inflammatory contexts of both acute infection and chronic autoimmunity in mice.

108 Post-SIV infection, MDSC were elevated in acute infection and persisted during 7 mo of combination

109 lication capacity of viruses isolated during acute infection predicts subsequent disease progression

110 n studies of cells in the brain that survive acute infection.

111 gether, our results support a model in which acute inflammation after injury initiates important rege

112 ors that actively regulate the resolution of acute-inflammation, and correlate measurements with clin

113 Silencing or acute inhibition of the formin mDia1 suppresses these ac

114 Acute inhibition or degradation of ATR in mitosis induce

115 Acute injection of recombinant cKL downregulated the ren

116 unknown program of liver regeneration after acute injury and allow for exploration of latent regener

117 Approximately, 64% went through the acute inpatient Medicare system without record of anythi

118 efficient use of intravenous thrombolysis in acute ischemic stroke (AIS).

119 favorable clinical outcomes in patients with acute ischemic stroke caused by intracranial proximal oc

120 Consecutive patients with acute ischemic stroke initially admitted to a non-thromb

121 t be withheld in these complex patients with acute ischemic stroke.

122 with symptomatic and sonographically proven acute isolated calf DVT.

123 r 1000 patient-years), including the rate of acute kidney injury (7.1 and 6.2 events per 1000 patient

124 Acute kidney injury (AKI) in children is associated with

125 y disease, failed ventilator liberation, and acute kidney injury +/- hemodialysis requirement.

126 One death in the everolimus group (acute kidney injury associated with diarrhoea), and two

127 s that showed the strongest association with acute kidney injury in a replication patient population

128 To examine whether acute kidney injury is associated with delirium and coma

129 Acute kidney injury is associated with high mortality, e

130 Acute kidney injury is common and is associated with poo

131 chloride for preventing contrast-associated acute kidney injury is marginal, if any.

132 Contrast-associated acute kidney injury was a secondary end point.

133 Severe acute kidney injury was associated with increased use of

134 the development of hyperchloremic acidosis, acute kidney injury, and survival among those with highe

135 Acute knockdown of Myt1l in the developing mouse brain m

136 ted changes in clinical status (specifically acute, Koch phenomenon-like reactions), lung function, o

137 In our studies of mouse models of acute leukemia, we used high-resolution microscopy and f

138 such as NR may be therapeutic in settings of acute liver injury.

139 Autophagy has a protective effect on acute liver injury.

140 r solely through resorption, we show that an acute loss of IFT-B through cilia decapitation precedes

141 ociated with 22% of all episodes of (severe) acute lower respiratory infection (ALRI) resulting in 55

142 e observed for duration or severity of other acute lower respiratory tract infection symptoms, durati

143 properties and dose-dependently counteracted acute lung eosinophilia in an experimental animal model.

144 usceptibility to silver nanoparticle-induced acute lung inflammation in mice.

145 he prominent features in the pathogenesis of acute lung injury (ALI).

146 romosome (Ph)-positive or Ph-negative B-cell acute lymphoblastic leukaemia who were due to receive fi

147 Philadelphia chromosome-like (Ph-like) acute lymphoblastic leukemia (ALL) is a high-risk subtyp

148 T-cell acute lymphoblastic leukemia (ALL) is a rare disease in

149 Philadelphia chromosome (Ph)-like acute lymphoblastic leukemia (ALL), also referred to as

150 T-cell acute lymphoblastic leukemia (T-ALL) is a highly prolife

151 cancers and primary, patient-derived B-cell acute lymphoblastic leukemia blasts compared with standa

152 adults with relapsed or refractory B-lineage acute lymphoblastic leukemia was conducted using a CD19

153 s of NOTCH1 (a well-known oncogene in T-cell acute lymphoblastic leukemia) are present in approximate

154 es are important risk factors for outcome in acute lymphoblastic leukemia.

155 orts a role for infection in the etiology of acute lymphocytic leukemia (ALL), and the involvement of

156 Children with moderate acute malnutrition (MAM) are treated with lipid-based nu

157 nicable diseases should be considered in the acute management and prevention of malaria.

158 on may be a promising therapeutic target for acute MI.

159 Conclusion In this study, patients with acute middle cerebral artery stroke with absence of cort

160 onth, change in the number of days of use of acute migraine-specific medication, and change in scores

161 neural and vascular deficits in chronic and acute mouse models of CCM3 loss in vivo, significantly r

162 f studies evaluating the predictive value of acute MRI lesion patterns for discriminating clinical ou

163 nal response of leukocytes in bone marrow of acute myeloid leukaemia (AML) patients, and the complex

164 duplication mutations in FLT3 are common in acute myeloid leukaemia and are associated with rapid re

165 tion in patients with relapsed or refractory acute myeloid leukaemia.

166 enzyme as a potential therapeutic target for acute myeloid leukaemia.

167 olic encephalopathy, neutropenic sepsis, and acute myeloid leukaemia]).

168 erior engraftment of primary patient-derived acute myeloid leukemia (AML) and other hematologic malig

169 able therapies, most patients diagnosed with acute myeloid leukemia (AML) die of their disease.

170 Purpose Elderly patients with acute myeloid leukemia (AML) have a poor prognosis, and

171 In this study, using acute myeloid leukemia (AML) human cell lines and a cust

172 receptor (CAR) T cells in preclinical human acute myeloid leukemia (AML) models at the cost of sever

173 CD33, which is expressed in the majority of acute myeloid leukemia (AML) patients.

174 established a mouse xenograft model of human acute myeloid leukemia (AML) that enabled chemotherapy-i

175 In acute myeloid leukemia (AML), therapy resistance frequen

176 ission chemotherapy in younger patients with acute myeloid leukemia (AML).

177 cMyc-driven antiproliferative activities in acute myeloid leukemia cell lines.

178 n of c-MYC, BCL2 and PTEN mRNAs in the human acute myeloid leukemia MOLM-13 cell line.

179 a detailed picture of the BM vasculature in acute myeloid leukemia using intravital two-photon micro

180 oid, Hodgkin lymphoma, non-Hodgkin lymphoma, acute myeloid leukemia, soft-tissue sarcoma, and central

181 cell lineages and a tendency to transform to acute myeloid leukemia.

182 additional criteria required for spontaneous acute myocardial infarction (280/397, 71%) versus those

183 emergency department patients with possible acute myocardial infarction (AMI) has been shown to effe

184 nts on dialysis revealed that mortality from acute myocardial infarction (AMI) has decreased, whereas

185 and increasing attention to young women with acute myocardial infarction (AMI), who represent an extr

186 nflammatory drugs (NSAIDs) use could trigger acute myocardial infarction (AMI).

187 A total of 1,230 patients with acute myocardial infarction (MI) treated with primary pe

188 arch Investigating Underlying Disparities in Acute Myocardial Infarction Patients' Health Status) is

189 c natural killer cell depletion 24 hours pre-acute myocardial infarction significantly improved infar

190 64 for mortality among patients admitted for acute myocardial infarction to 2615 for mortality among

191 125 231 hospitalizations for heart failure, acute myocardial infarction, and pneumonia, respectively

192 ly administered off-the-shelf early after an acute myocardial infarction, comply with stringent crite

193 exhibited significantly (p < 0.05) decreased acute necrotic/apoptotic injury and significantly (p < 0

194 experienced operators, leading in turn to an acute need for novel test evaluation.

195 Delirium is a serious acute neurocognitive condition frequently occurring for

196 infectious and non-infectious causes of this acute neurological illness.

197 These data indicate that in this model of acute, neutrophil-dependent glomerulonephritis, NETs are

198 s on serotonergic cells were dispensable for acute nociceptive behaviors and for aversion induced by

199 lly in patients with multiple organ failure (acute-on-chronic liver failure grade 2-3).

200 Acute or chronic stimulation by IL-4 modified expression

201 There were no acute or late grade 5 toxic effects.

202 In children aged <3 years, acute otitis media developed in 58%, and 66% of children

203 The morbidity rate of hypertriglyceridemic acute pancreatitis (HTG-AP) increased rapidly over the l

204 Among 6,161 cases of acute pancreatitis and 61,637 controls, current use of a

205 REPORT: A 44-year-old man with a history of acute pancreatitis developed a pseudoaneurysm of the pan

206 logical prevention or specific treatment for acute pancreatitis exists.

207 rs might be associated with a lesser risk of acute pancreatitis, and that the protective association

208 blockers was followed by a decreased risk of acute pancreatitis, compared to non-users, adjusted OR 0

209 cute coronary syndrome, and the incidence of acute pancreatitis, pancreatic cancer, medullary thyroid

210 nificant among cases of both severe and mild acute pancreatitis.

211 ANCE RSV and HPIV1 are major viral causes of acute pediatric respiratory illness for which no vaccine

212 ional epigenetic modification in response to acute periods of starvation.

213 r surface inflammation was common during the acute phase in both SJS and TEN.

214 nsive lowering of blood pressure (BP) at the acute phase of intracerebral haemorrhage (ICH) is benefi

215 ntified as a carboxy-terminal peptide of the acute phase protein serum amyloid A (SAA) 1.

216 nal lesions and of the optic disc during the acute phase showed no statistically significant differen

217 The acute-phase protein serum amyloid A (A-SAA) was signific

218 talyze fluctuations in the concentrations of acute-phase proteins and certain micronutrient biomarker

219 ription factor known to regulate the hepatic acute-phase response and lipid homeostasis.

220 transcripts associated with inflammatory and acute-phase responses, coagulative activities, and trans

221 We studied the effects of acute physical exercise on the cerebral mu-opioid recept

222 We used a recalibrated Simplified Acute Physiology 3 model and examined model performance

223 y goal-directed therapy and control included Acute Physiology and Chronic Health Evaluation II (relat

224 ents (median age, 58.8 years; median APACHE [Acute Physiology and Chronic Health Evaluation] II score

225 l admission, comorbidity, and low Simplified Acute Physiology Score 3.

226 Acute promyelocytic leukemia (APL) is commonly complicat

227 a PML-RARalpha fusion protein causative for acute promyelocytic leukemia (APL).

228 L-RARalpha) oncofusion protein, which causes acute promyelocytic leukemia, inhibits TNFalpha induced

229 Risk stratification for acute pulmonary embolism using imaging presence of right

230 ntricular size and function in patients with acute pulmonary embolism.

231 We found, in acute rat OB slices from both sexes, that inhibitory syn

232 uromodulation by neuroestrogens concerns the acute regulation of sensory coding by the auditory corte

233 Glucocorticoid (GC)-refractory acute rejection (AR) is a risk factor for inferior renal

234 ts surviving at least 90 days, early events (acute rejection [AR] and delayed graft function [DGF] be

235 The adjusted hazard ratio for acute rejection and all-cause mortality at 3 years in re

236 Unlike allograft samples showing acute rejection, samples from FCRx recipients did not sh

237 standing diabetes might increase the risk of acute rejections.

238 rhoea and urinary sepsis in one patient, and acute renal failure and respiratory failure in one patie

239 In the latter patient, acute renal failure was not suspected to be related to e

240 This serological response is compatible with acute, resolved, and chronic hepatitis B virus (HBV)infe

241 cytotoxic T cell responses characterized as acute resolving or inflationary.

242 RATIONALE: Acute respiratory distress syndrome (ARDS) is caused by

243 RATIONALE: Following acute respiratory distress syndrome (ARDS), joblessness

244 echanical ventilation in adult patients with acute respiratory distress syndrome (ARDS).

245 (NIV) is increasingly used in patients with acute respiratory distress syndrome (ARDS).

246 eriod, 469 patients (18 tuberculosis-related acute respiratory distress syndrome and 451 acute respir

247 After induction of acute respiratory distress syndrome by hydrochloric acid

248 olume, Cdyn, and PaO2/FIO2 were collected at acute respiratory distress syndrome onset and at 24 hour

249 At acute respiratory distress syndrome onset, neither mecha

250 In a multisite cohort of long-term acute respiratory distress syndrome survivors, better an

251 One hundred fifty-six acute respiratory distress syndrome survivors.

252 e respiratory distress syndrome-others) with acute respiratory distress syndrome were admitted.

253 ies suggest hypothermia may be beneficial in acute respiratory distress syndrome, but cooling causes

254 During the acute respiratory distress syndrome, epithelial cells, p

255 acute respiratory distress syndrome and 451 acute respiratory distress syndrome-others) with acute r

256 y associated with a lower incidence of early acute respiratory distress syndrome.

257 educe the severity of rodent E. coli-induced acute respiratory distress syndrome.

258 European Consensus Conference definition of acute respiratory distress syndrome.

259 Consecutive subjects with acute respiratory distress syndrome.

260 ations in subjects with mild COPD or similar acute respiratory events in smokers without airflow obst

261 In subjects without airflow obstruction, acute respiratory events were not associated with additi

262 urvival benefits in unselected patients with acute respiratory failure.

263 sion during sentinel surveillance for severe acute respiratory illness (SARI) hospitalization conduct

264 Controls were subjects with acute respiratory illness testing negative for influenza

265 sure, breathing problems, tiring easily, and acute respiratory illnesses.

266 Previous studies have suggested that acute respiratory infection (ARI) and nonsteroidal anti-

267 with Middle East respiratory syndrome severe acute respiratory infection from other etiologies; there

268 tic testing is essential component of severe acute respiratory infection investigation for at-risk pa

269 an pathogens hepatitis C virus (HCV), Severe acute respiratory syndrome (SARS), coxsackie viruses, an

270 OR = 0.12; 95% CI: 0.06-0.26) against severe acute respiratory syndrome (SARS).

271 Severe acute respiratory syndrome coronavirus (SARS-CoV) causes

272 Severe acute respiratory syndrome coronavirus (SARS-CoV) is a h

273 improved by the use of NPPV in children with acute severe asthma with respiratory muscle fatigue and

274 euronal function during ischemic attacks and acute severe hypoglycemia.

275 tly protects from excessive inflammation and acute shock in vivo.

276 y aimed to assess the effects of 0.5% PVI on acute skin wounds.

277 Among adults presenting to primary care with acute sore throat, a single dose of oral dexamethasone c

278 tial prognostic utility in patients after an acute ST-segment-elevation myocardial infarction (STEMI)

279 In the acute stage, amusic patients exhibited decreased activat

280 Their recruitment to damaged tissues upon acute sterile injuries is necessary for clearance of nec

281 response to a stressor.Animals' response to acute stress is known to be influenced by sex and geneti

282 Furthermore, we find that acute stress preferentially activates neuronal subpopula

283 ted this association across a large range of acute stressors.

284 on in a subgroup analysis of patients in the Acute Stroke or Transient Ischaemic Attack Treated with

285 he prevalence of associated risk factors for acute stroke.

286 areas of slow conduction resulted in a high acute success.

287 seizures (14.3%, 6.3-29.4) and survivors of acute symptomatic CSE (13.3%, 3.7-37.9) than in those of

288 Acute T1 values were a strong predictor of 6-month wall

289 cians have recognized aortic aneurysms as an acute threat to life.

290 remains a challenge in clinical treatment of acute thrombo-occlusive diseases.

291 be considered in patients presenting with an acute TMA, especially in patients with nondeficient ADAM

292 l translation of vaccine-adjuvants: reducing acute toxicities that result from systemic diffusion of

293 There were no indications of acute toxicity up to 7 days after instillation.

294 We also observed an acute, transient increase in a population of CD11b+ myel

295 In acute/transient ER stress, decreased global protein synt

296 (DANish Study of Optimal Acute Treatment of Patients With ST-elevation Myocardial

297 Acute tubular and glomerular renal injury was accompanie

298 Acute upper gastrointestinal bleeding is a leading indic

299 SE REPORT: A 50-year-old male presented with acute urinary retention.

300 setting thermal limits by investigating the acute warming response of six Antarctic marine invertebr