ライフサイエンスコーパス: acute disease

1 plotype had reduced plasma MIF levels during acute disease.

2 on in children with malaria, but only during acute disease.

3 e functions that change during the course of acute disease.

4 t recipients receiving prophylaxis to reduce acute disease.

5 ced IFN-gamma does not alter the severity of acute disease.

6 ) are required for the development of severe acute disease.

7 , while infection with JHM.IA resulted in no acute disease.

8 ection, is not essential for inflammation in acute disease.

9 ntioxidant protection (R =.48; p =.00067) in acute disease.

10 in inducing specific CD8+ T cells during the acute disease.

11 r, but only a subset went on to develop more acute disease.

12 on recovered normally from passively induced acute disease.

13 eath (AICD) in the spontaneous recovery from acute disease.

14 d IL-10 (Ad-5/IL-10) reduced the severity of acute disease.

15 se, and the mice recovered more quickly from acute disease.

16 3 billion just for those found to be free of acute disease.

17 with rapid, high-level viral replication and acute disease.

18 required for the in vitro properties or for acute disease.

19 irectly related to signs and symptoms during acute disease.

20 9 exhibited a high prevalence of ANCA during acute disease.

21 pha, interleukin-10, and interferon-gamma in acute disease.

22 fection having completely recovered from the acute disease.

23 obability approaching 0% for those with mild acute disease.

24 om the qRT-PCR analysis done in blood during acute disease.

25 navirus 2 (SARS-CoV-2) can cause chronic and acute disease.

26 s acquired or correlate with protection from acute disease.

27 lbeit developing quicker after recovery from acute disease.

28 , by components of plasma from patients with acute disease.

29 polysaccharide I (CPS I) to virulence during acute disease.

30 38), as previously reported in a cohort with acute disease.

31 oup and none in the combined group developed acute disease.

32 er from cognitive impairment long time after acute disease.

33 e analyzed to identify the major features of acute disease.

34 e encephalitis (JE) is a vaccine-preventable acute disease.

35 amsters, a species particularly sensitive to acute disease.

36 of long-term residency within the horse post-acute disease.

37 -17A's ability to induce Th2 inflammation in acute disease.

38 y higher in the CNS at remission than during acute disease.

39 fever with renal syndrome (HFRS) is a severe acute disease.

40 ere also reduced in Panx1 KO EAE mice during acute disease.

41 1 does not contribute to the pathogenesis of acute disease.

42 enal fibrosis in mouse models of chronic and acute disease.

43 al, unknown trigger is needed to bring about acute disease.

44 o obtain CSF was performed 1.5-7 years after acute disease.

45 ng virus-host interactions in persistent and acute disease.

46 midine is also effective in a mouse model of acute disease.

47 ntly lower than those found in patients with acute disease.

48 nt the high-level bacteremia associated with acute disease.

49 r novel, host cell-focused therapies against acute diseases.

50 tus of the individual and early diagnosis of acute diseases.

51 ing a key strategy in addressing chronic and acute diseases.

52 tic indicator or predicting other chronic or acute diseases.

53 uses may be implicated in chronic as well as acute diseases.

54 tions are linked to multiple degenerative or acute diseases.

55 ilable in six patients and were decreased in acute disease (0.29 +/- 0.02 g/L) compared with convales

56 tive colitis during the study period: 73 for acute disease, 18 for advanced age and/or comorbidities,

57 f transferrin was significantly increased in acute disease (36.9% +/- 2.5%) compared with convalescen

58 issue activation in the head and neck during acute disease, a generalised pattern of peripheral lymph

59 gly, BIO 5192 treatment begun at the peak of acute disease accelerated entrance into disease remissio

60 nstructed from MRI-is highly associated with acute disease activity, both in the studied mouse models

61 nalogues, can be used to monitor episodes of acute disease activity.

62 ph (CXR) findings were classified as showing acute disease (AD; n=101) or no AD (NAD; n=92).

63 cue fibrotic disease after the resolution of acute disease, addressing a current unmet need in the cl

64 tients with COVID-19 with severe or moderate acute disease, after recovery, and prepandemic healthy i

65 Designed to respond episodically to acute disease, almost all historical investment has focu

66 six types of EEHV in blood of elephants with acute disease, although EEHV1A is the predominant pathog

67 on of T(H)1-associated genes was detected in acute disease, although some were significantly upregula

68 iphasic disease, with T(H)2 predominating in acute disease and a switch to T(H)1 characterizing chron

69 tudinal profiling of immune responses during acute disease and following recovery in children who dev

70 riven classical pathway stimulus during both acute disease and in many patients during clinical remis

71 CD4 and CD8(+) T cells were detected during acute disease and maintained to 12 years, but these decl

72 Understanding how ECM components aid acute disease and persistence could lead to improvements

73 ile therapeutics with potential for limiting acute disease and promoting bacterial decolonization.

74 ation, immunosuppression, or parturition) to acute disease and recrudescence from persistent SVA infe

75 le, as indicated by blocking and reversal of acute disease and reduced number of relapses and diminis

76 Prophylactic anti-IL-17A prevents acute disease and relapse and is associated with reduced

77 s may contribute to the clinical features of acute disease and represents a potential novel target fo

78 useful marker for leukemia in patients with acute disease and suggest a role for CREB in leukemogene

79 f drugs targeting short course therapies for acute diseases and towards long-term treatment of chroni

80 ticipate actively in the pathogenesis of the acute disease, and harbor the virus chronically, allowin

81 of T and B cell genes) persisted beyond the acute disease, and immune dysregulation was greatly impa

82 ecific imaging modality for the diagnosis of acute disease, and it helps in the management and progno

83 asma exchange, and pulse cyclophosphamide in acute disease, and strategies to prevent relapse over th

84 The adaA (acute disease antigen A) gene was detected in acute grou

85 Viral clearance and acute disease are associated with a strong, polyclonal,

86 oals infused with nonimmune plasma developed acute disease associated with high levels of the predomi

87 e brain during several neurodegenerative and acute diseases associated with infiltration of periphera

88 ed with improved management of patients with acute disease because it accurately predicts short-term

89 Ab's between 26 and 35 weeks of age reversed acute disease, blocked chronic disease, and extended the

90 Although the acute disease burden is sizeable, emerging data suggest

91 tomegalovirus (CMV) prophylaxis prevents the acute disease but its impact on subclinical infection an

92 IL-17A expression seems significant during acute disease but less important chronically.

93 n at this position (T81W) produced a similar acute disease but was attenuated for the development of

94 Many human viruses not only cause acute diseases but also establish persistent infections.

95 sets tolerized to MOG were protected against acute disease, but after tolerization treatment a lethal

96 e activated and initiate regeneration during acute disease, but lose this ability during the chronic

97 Four patients (9%) died during the acute disease, but most showed marked improvement with i

98 ate the clearance of infectious virus during acute disease by cell-mediated immunity.

99 The acute disease caused by ADV consists of permissive infec

100 may have direct application in prevention of acute disease caused by intracellular bacterial pathogen

101 Chikungunya virus (CHIKV) infection causes acute disease characterized by fever, rash and arthralgi

102 -/- mice suffered an early and a more severe acute disease characterized by incomplete recovery when

103 High altitude and cold involve acute disease, chronic disease, and public health issues

104 plasmids that were originally isolated from acute-disease, chronic-disease, and severely attenuated

105 the treated group) and significantly reduced acute disease (clinical index of 4.3 +/- 0.7 in the untr

106 hould be considered a chronic rather than an acute disease condition, and have implications for the m

107 taken over a nine month period encompassing acute disease, convalescence, and recovery.

108 Prevention of acute disease could improve long-term lung health, with

109 tation (SBMT), when performed at the peak of acute disease (day 14), prevented glial scarring and ame

110 During acute disease, dengue-specific CD8(+) T cells expressed

111 Acute disease developed with equal kinetics and severity

112 ither CD28 peptide mimic administered during acute disease dramatically improved clinical signs of EA

113 iral hepatitis in four U.S. counties who had acute disease during 1985 to 1986 or 1991 to 1995.

114 disease initiation or during remission from acute disease effectively blocks the expression of the i

115 Study I examined acute disease, either first presentation or relapse (Bir

116 which are scientifically less applicable to acute-disease endpoints.

117 ion in experimentally infected equids during acute disease episodes and during asymptomatic infection

118 ed by youth and a susceptibility to repeated acute disease episodes.

119 Acute disease exacerbations, due frequently to viral inf

120 ntries, resulting in detailed reports of the acute disease following EBOV infection as well as descri

121 nstrates the benefit of antiviral therapy of acute disease for long-term respiratory health.IMPORTANC

122 thod may provide a promising means to manage acute disease for personalized medicine.

123 ical data analysis phenotypes differentiated acute disease from health and acute cardiorespiratory ex

124 ponders (group A, n=11) and untreated active/acute disease (group B, n=9) and compared to Caucasian h

125 Fifty-six percent of patients with acute disease had an improved maximal incisal opening af

126 In addition to acute disease, high altitude involves chronic mountain s

127 infection usually results in a self-limiting acute disease; however, in infected pregnant women, it i

128 ANCE Hepatitis E is usually a self-resolving acute disease; however, in pregnant women, HEV infection

129 t also play an early role in protection from acute disease.IMPORTANCE Syrian hamsters are in use as a

130 these cell types in vitro and in vivo during acute disease in a mouse model of S. aureus craniotomy i

131 S-CoV-2 IgG antibodies, distinguishable from acute disease in children but with antibody levels simil

132 osoma cruzi, can reactivate and cause severe acute disease in immunocompromised patients such as thos

133 aemocanis is a blood pathogen that may cause acute disease in immunosuppressed or splenectomized dogs

134 redominant sites of virus replication during acute disease in infected equids and serve as resilient

135 sis is a highly infectious bacterium causing acute disease in mammalian hosts.

136 length or secreted gD2 significantly reduced acute disease in mice and guinea pigs (both P<.001) and

137 alphavirus chikungunya virus (CHIKV), cause acute disease in millions of people and utilize potent m

138 nged with group I isolates, mild to moderate acute disease in response to group V isolates, and no ac

139 ctivation in these cultures, and produced an acute disease in rhesus and pigtail macaques.

140 Ebola virus/Yambuku-Mayinga infection during acute disease in rhesus macaques.

141 Development of acute disease in successfully vaccinated individuals is

142 pretation of serologic testing in diagnosing acute disease in symptomatic individuals.

143 ers S. equi significantly less able to cause acute disease in the natural host.

144 ev region from the avirulent parent, induced acute disease in two animals, while a similar infectious

145 cline, it is not known whether it relates to acute disease in younger healthy populations.

146 infections, including bacteraemia and other acute diseases in adults and immunocompromised individua

147 chronic diseases or can reactivate to cause acute diseases in AIDS patients or patients receiving im

148 cting contagion and the immediate outcome of acute diseases in previously healthy individuals is larg

149 Ducks developed acute disease, including severe neurological dysfunction

150 r cycle length and consisted of five states: acute disease, indeterminate disease, cardiomyopathy wit

151 e most advanced in development are targeting acute disease indications such as stroke, myocardial inf

152 During acute disease, infiltrating CD8(+) T cells secrete gamma

153 Acute disease is associated with C. jejuni invasion of t

154 The acute disease is characterized by systemic mycobacterial

155 ce of optimal chemotherapeutic intervention, acute disease is frequently fatal.

156 In the absence of IL-2, the acute disease is mild because of reduced T cell effector

157 tions yearly, long-term survival after these acute diseases is not well characterized.

158 ons in ruminant livestock and humans with an acute disease known as Q fever.

159 Many who survive the acute disease later experience post-Ebola syndrome, a co

160 However, challenges remain in treating acute diseases mainly due to their inability to timely a

161 CD16(+) T cell clones persisted beyond acute disease maintaining their cytotoxic phenotype.

162 dermal drug delivery for rapid and on-demand acute disease management.

163 Acute disease of the upper respiratory tract usually inv

164 the simplest cases: short-term prediction in acute diseases of otherwise healthy persons.

165 sease phase but increase significantly after acute disease onset on cardiomyocyte death and fibrotic

166 10, and 15 to examine the effect of RvD1 on acute disease or administered the same dose on days 60,

167 154 antibody treatment at either the peak of acute disease or during remission effectively blocked cl

168 contrast, Ab treatment either at the peak of acute disease or during remission exacerbated disease re

169 blood cells were isolated during the initial acute disease or from asymptomatic animals and analyzed

170 al hearing loss (SNHL) in the late stages of acute disease or in early convalescence.

171 r VB families revealed their presence during acute disease or relapses but, with the exception of VB1

172 ere depleted immediately before the onset of acute disease, or during the chronic stage, a striking a

173 d to P. vivax infection; in the remaining 4, acute diseases other than malaria were found to be the c

174 ogle Trends was most suitable for monitoring acute disease outbreaks at the regional level in high-in

175 n to modulate immune responses and influence acute disease outcomes, suggesting that mTreg recall may

176 lth development among patients with a severe acute disease phase of COVID-19.

177 ciated with chronification in acute and post-acute disease phases.

178 The causal relationships between acute disease phenotypes, long-term symptoms, and involv

179 ease who do not meet the case definition for acute disease pose a low infection risk to health-care p

180 and IL-10(-)CD8 T cells interconvert during acute disease, possibly based on recent Ag exposure.

181 V-specific T-cell responses generated during acute disease predominantly target ORF2, but decline in

182 osts, and this is often associated with more acute disease presentation.

183 osis of leptospirosis are still lacking, and acute disease presents with nonspecific symptomatology a

184 sease: Improving Global Outcomes (KDIGO) and Acute Disease Quality Initiative (ADQI) criteria were us

185 The 23rd Acute Disease Quality Initiative (ADQI-23) consensus con

186 Here, we provide recommendations from the Acute Disease Quality Initiative consensus meeting, whic

187 ssified as acute kidney disease according to Acute Disease Quality Initiative definition and 44 patie

188 At the 26th Acute Disease Quality Initiative meeting conducted in No

189 The 33rd Acute Disease Quality Initiative meeting evaluated avail

190 dult patients that was developed at the 34th Acute Disease Quality Initiative meeting, which convened

191 agement and follow-up of PrAKI from the 32nd Acute Disease Quality Initiative meeting, which involved

192 In this Consensus Statement, the Acute Disease Quality Initiative provides recommendation

193 In this study, we demonstrate Acute Disease Quality Initiative to allow recovery patte

194 CRP treatment of NZB/NZW mice during acute disease rapidly decreased proteinuria, and the tre

195 In the cuprizone model, acute disease reduces serum cholesterol levels that can

196 prognostic cohort study of 3606 adults with acute diseases referred to 5 tertiary care hospitals in

197 ranscriptional and cytokine responses during acute disease reflected dominant type I/II interferon si

198 n contrast, uPAR-/- mice had a delayed, less acute disease reflected in delayed infiltration of infla

199 r endogenous myelin epitopes released during acute disease, reflecting a critical role for epitope sp

200 termine whether IVCCM can be used to detect (acute) disease relapse.

201 Reductions in acute disease-related mortality have now shifted focus t

202 ral IL-17A mRNA expression quantified during acute disease, remission, and relapse.

203 actors were more likely to experience severe acute disease, requiring hospitalisation.

204 However, the acute disease resolved, and the CB6F(1) mice went on to

205 Hantavirus pulmonary syndrome (HPS) is an acute disease resulting from infection with any one of a

206 f convergent evolution in isolates from post-acute disease samples as a result of niche adaptation to

207 parable age and sex hospitalized for another acute disease (SARS-CoV-2 negative), and (c) healthy con

208 Horses with acute disease served as a basis for comparison.

209 with higher tissue susceptibility had worse acute disease severity, higher acute inflammatory marker

210 x (MHC) class I, and perforin contributed to acute disease signs at 8 days postinfection (p.i.).

211 ients with anti-NMDAR encephalitis after the acute disease stage and 25 healthy control subjects unde

212 st patients are severely affected during the acute disease stage, but long-term functional recovery i

213 often severe, and usually persist beyond the acute disease stage, interfering with patients' recovery

214 d patients with MOGAD/AQP4+NMOSD/RRMS in non-acute disease stage.

215 ui within the horse is defined by short-term acute disease, strangles, followed by long-term infectio

216 d highly specific enrichment patterns in all acute disease subgroups, for example, selective enrichme

217 Aggressive approaches to acute diseases such as acute myocardial infarction, trau

218 tem for mLcn2 in studies of animal models of acute diseases such as kidney and cardiac failure.

219 The introduction of vaccination against acute diseases such as measles induced a dramatic declin

220 Severe acute diseases, such as COVID-19, require targeted and i

221 Chronic diseases have overtaken acute diseases, such as infections, as the major cause o

222 ylori) is responsible for various chronic or acute diseases, such as stomach ulcers, dyspepsia, pepti

223 arameters and in a guinea pig fever model of acute disease, suggesting a difference in virulence pote

224 nsory, neurons.IMPORTANCE Stress exacerbates acute disease symptoms resulting from HSV-1 and HSV-2 in

225 ontrol rapid parasite expansion and mitigate acute disease symptoms.

226 in-2(-/-)mice leads to a rapid appearance of acute disease symptoms.

227 -CoV-2 nasopharyngeal swab (NPS) results and acute disease symptoms.

228 ble axonal dysfunction, which coincides with acute disease symptoms.

229 xtensive lymphocyte activation and induce an acute disease syndrome in macaque monkeys.

230 ral mononuclear cell cultures and induces an acute disease syndrome in macaque monkeys.

231 Our data indicate that the acute disease syndrome induced by SIVmac239/YEnef is not

232 iated hepatitis (AH) is a clinically severe, acute disease that afflicts only a fraction of patients

233 the difficulties in managing cases of severe/acute disease that are at high risk of relapse.

234 ntration of Legionella pneumophila causes an acute disease that is resolved by innate immune response

235 d adaptive immune activation pathways during acute disease that, despite reduced immunosuppressant us

236 Arboviruses cause acute diseases that increasingly affect global health.

237 features, including the rapid development of acute disease, the episodic nature of chronic disease, t

238 During acute disease, the predominant cellular site of viral in

239 iruses affect host physiology beyond causing acute disease, thereby giving rise to the concept that t

240 ple with covid-19, from those with very mild acute disease to the most severe forms.

241 g acute infection, consistent with a role in acute disease tolerance.

242 Acute disease was also associated with significant incre

243 Incidence of acute disease was calculated among 16,683 participants (

244 Acute disease was characterized by significant weight lo

245 A, USA) in Malawian NTS cases (n=106) during acute disease was correlated with genotype by linear reg

246 More severe acute disease was linked with CT abnormalities at 3 mont

247 genic events are required for progression to acute disease, we crossed hMRP8p210BCR/ABL mice to apopt

248 like the T-cell infiltrates that peak during acute disease, we found that microglia activation persis

249 Isolates associated with acute disease were found to be distinct from a group of

250 those isolated from naive mice or mice with acute disease, were able to endogenously present a varie

251 Guinea pigs developed severe acute disease when aerosol challenged with group I isola

252 ease in response to group V isolates, and no acute disease when infected with group IV and VI isolate

253 ein-reactive cells infiltrate the CNS during acute disease, whereas affinities during remission, rela

254 ely related to known genotypes from cases of acute disease, whereas the seven loci (4.0 kb) obtained

255 and CCL5, were prominently expressed during acute disease, whereas transcripts for CXCL9, CXCL10, an

256 high level of HIV gene expression developed acute disease which resulted in premature death, and mic

257 le was seen in pediatric patients during the acute disease, which resolved at the subacute and conval

258 UL19/UL47 adenovirus groups developed severe acute disease, while 2/8 animals in the gC2/gD2-only gro

259 play an important role in protection against acute disease, while both CD4 T cells and antibodies are

260 la pertussis is the etiological agent of the acute disease whooping cough in infants and young childr

261 Both of these cause acute disease (whooping cough), whereas their progenitor

262 n that causes source-originated epidemics of acute disease with a case fatality rate thought to vary

263 Treatment of acute disease with approved antivirals, paxlovid-like ni

264 s (DENV) that ranges from febrile illness to acute disease with serious complications.

265 tand breath metabolite network enrichment in acute disease, with a view to gaining mechanistic insigh

266 nce was significantly associated with severe acute disease, with probability of persistence in this p

267 detectable infection of challenge virus and acute disease within several weeks.

268 20%) was characterized by a more aggressive acute disease within the 48 hours preceding ICU admissio

269 V-2 variants have contributed to more severe acute disease worldwide.