ライフサイエンスコーパス: acute phase

1 4 h (hyperacute phase) and 12 over days 2-7 (acute phase).

2 rasite load within the myocardium during the acute phase.

3 characterized by vascular alterations in the acute phase.

4 , and reversal of anticoagulation during the acute phase.

5 had a second troponin measurement during the acute phase.

6 e detection of dengue virus infection in the acute phase.

7 ntended to curtail renal inflammation in the acute phase.

8 ccurs without causing adverse effects in the acute phase.

9 a rapid and significant loss of axons in the acute phase.

10 esting prior to revascularization during the acute phase.

11 years), strong connections were found in the acute phase.

12 hepatitis C virus (HCV) infection during the acute phase.

13 ted with life-threating complications in the acute phase.

14 ifest restricted joint movements at the post-acute phase.

15 physiological reactivity were central in the acute phase.

16 th abbreviated courses of therapy during the acute phase.

17 Several of the acute-phase adaptations to critical illness are due to o

18 is of native T1 maps already revealed in the acute phase after MI substantial discrepancies in myocar

19 the association between PTSD symptoms in the acute phase after trauma and the chronic phase.

20 Twenty-nine CRAO cases at acute phase and 33 normal controls were included.

21 a significant morbidity and mortality in the acute phase and an increased risk of developing End Stag

22 TNF as beneficial and neuroprotective in the acute phase and as a modulator of neuroinflammation at l

23 FM) Scale to measure motor impairment in the acute phase and at 3 months.

24 e phase response in liver, and characterized acute phase and detoxification responses in quantitative

25 endoscopy by an otorhinolaryngologist in the acute phase and during follow-up at 2 and 12 months were

26 nsistent with structural perturbation in the acute phase and neurobiochemical changes (P-Tau and GFAP

27 onsists of the use of pharmacotherapy in the acute phase and of psychotherapy in its residual phase.

28 tly induced by cellular sulfide stress in an acute phase and specific response and that cst-encoded g

29 remarkable decrease in parasitemia levels in acute phase and the parasitemia reactivation following i

30 he incidence of malignant arrhythmias in the acute phase and was not associated with an increase in a

31 fection also correlated positively with both acute-phase and chronic viremia.

32 nisms that regulate IFN levels following the acute phase are unknown.

33 Finally, a positive correlation between the acute-phase area under the curve (AUC) for IL-6 and solu

34 An elevated chymase level in acute phase blood samples was highly indicative of later

35 /-0.76 mm/mm2; P=0.003) as compared with the acute phase, but were still significantly lower when com

36 potent target for stroke treatment after the acute phase by fostering angiogenesis and neuroregenerat

37 We recently reported that the acute-phase C4BP isoform C4BP lacking the beta-chain pla

38 e of corticospinal tract (CST) injury in the acute phase can predict motor outcome at 3 months in com

39 T-LL, an imaging biomarker determined in the acute phase, can predict poststroke motor outcomes at 3

40 By targeting STAT3-dependent acute-phase changes in the liver, we evaluated the role

41 Remarkably, PBMCs from patients with acute-phase chronic obstructive pulmonary disease, which

42 ssessment of motor impairment (UE-FM) in the acute phase correlated with motor impairment (UE-FM) at

43 n was associated with stronger corresponding acute-phase cytokine/chemokine responses than the nonpro

44 , our studies provide evidence of OAS in the acute-phase dengue virus immune response, providing a ba

45 IPT for acute-phase depression had moderate-to-large effects com

46 EM has a poor prognosis during the acute phase, despite a publication bias that could have

47 e versus the chronic phase (RHacute) and the acute phase duration (dacute) by fitting a couples trans

48 as excess hazard-months attributable to the acute phase (EHMacute) can be estimated more precisely:

49 ing compensatory mutations did not result in acute-phase escape of the SIVmac239 CD8(TL) epitope Gag(

50 (CO6980v0c22) from an infected person in the acute phase (Fiebig stage I/II) was developed as a resea

51 The acute phase (first hours to days) is characterized by an

52 mages were assessed at 3 time points: at the acute phase (first visit to the cornea service), at cess

53 sessions of CBASP or SP for 20 weeks in the acute phase, followed by 8 continuation sessions during

54 Studies of adults who had MRI in the acute phase following moderate or severe traumatic brain

55 ity to distinguish a long, mildly infectious acute phase from a short, highly infectious acute phase,

56 excess physiological infectivity during the acute phase from couples data, but not the proportion of

57 lpha signaling pathway, which then activates acute-phase genes such as serum amyloid proteins and oro

58 acute phase from a short, highly infectious acute phase, given the 10-mo Rakai observation intervals

59 nificantly stronger at 12 months than in the acute phase (global strength values, 6.57 vs 7.60; paire

60 of the infract in the fundus seen during the acute phase gradually resolved in about 2-3 weeks, leavi

61 The infectivity of the HIV-1 acute phase has been directly measured only once, from a

62 ced an increased risk of new-onset HF in the acute phase (hazard ratio, 1.62; 95% confidence interval

63 Hepcidin is an endogenous acute phase hepatic hormone that prevents iron export fr

64 e, small ischemia studies show reductions in acute-phase hsCRP production with the IL-1 receptor anta

65 Patients were examined at 2 to 3 days (acute phase I) and 8 to 10 days (acute phase II), and so

66 prefrontal and parietal regions, as early as acute phase I.

67 to 3 days (acute phase I) and 8 to 10 days (acute phase II), and some of them at 4 to 6 months (chro

68 During acute phase II, favorable recovery from neglect was asso

69 r surface inflammation was common during the acute phase in both SJS and TEN.

70 nerves were reduced significantly during the acute phase in eyes with IK compared with controls acros

71 Indeed, mortality reported during the acute phase in hospitalized patients is approximately 4%

72 n RNAs by RNA-binding proteins (RBPs) and an acute phase in which expansion RNAs exceed RBP sequestra

73 evels were IFN responsive, increasing during acute phase infection and decreasing during a more quies

74 nfection, under the assumption that elevated acute phase infectivity is caused by elevated viral load

75 Elevated acute phase infectivity is therefore less likely to unde

76 We estimated acute phase infectivity using two approaches.

77 these are substantial overestimates of HIV-1 acute phase infectivity, biased by unmodeled heterogenei

78 Increased markers of oxidative stress and acute-phase inflammation are prevalent in patients under

79 Its acute phase is associated with high parasitism, myocardi

80 cohort underlie the widespread view that the acute phase is highly infectious, even more so than woul

81 rlying SVD and the extent of bleeding at the acute phase is unknown to date.

82 nificant differences in ADIR and ADBR in the acute phase (LSMD: +0.11%; 95% confidence interval [CI]:

83 In its acute phase lung injury induced by tissue or bacterial p

84 IL-1alpha or Tox3 overexpression during the acute phase of a CNS insult may be an effective means fo

85 the contrary, is a commonly used drug in the acute phase of acute coronary syndromes to relieve pain-

86 efore, the optimal cut-off by CMR during the acute phase of an MI to predict viability was </=75% TEI

87 ance (CMR) for defining viability during the acute phase of an MI, using </=50% TEI at follow-up as t

88 of IFN-gamma in the cecal mucosa during the acute phase of an S. Typhimurium infection.

89 However, in the acute phase of an ST-segment elevation myocardial infarc

90 plasma kallikrein, and kininogen during the acute phase of anaphylaxis but not at basal conditions o

91 ctional network connectivity obtained in the acute phase of CA were independently associated with FO

92 FN-gamma are important for recovery from the acute phase of CDI.

93 howing excellent in vivo behavior during the acute phase of Chagas disease; and (iii) neither nonspec

94 Reduced joint pathology during early acute phase of CNR20235 infection was associated with a

95 roendocrine responses to such fasting in the acute phase of critical illness has shown to beneficiall

96 A high catabolic rate characterizes the acute phase of critical illness.

97 iously and were detected early following the acute phase of disease.

98 developed robust immune responses during the acute phase of Ebola virus infection, a finding that wou

99 of the hippocampal network, at least in the acute phase of epilepsy.

100 alling is initially downregulated during the acute phase of epithelial injury as the mesenchyme proli

101 d by the majority of circulating ASCs in the acute phase of EV71 infection.

102 roduced by tmACs and sAC is required for the acute phase of extracellular signal regulated kinase 1/2

103 active CD8 T cells are infrequent during the acute phase of HIV-1 infection.

104 lable on the cellular immune response in the acute phase of human ZIKV infection, and its role in the

105 1) and/or plasmapheresis (n = 13) during the acute phase of HUS had comparable outcomes.

106 e detected strong upregulation of tPA in the acute phase of illness and in PUUV-infected macaques and

107 s with higher initial viral loads during the acute phase of illness had poor prognosis at the post-ac

108 threshold values for fatal cases during the acute phase of illness were significantly lower than tho

109 oads similar to those in patients during the acute phase of IM and a cell-mediated immune response th

110 they resembled those in patients during the acute phase of IM in timing and quality, were never as e

111 were as high as those in patients during the acute phase of IM, whereas the cell-mediated responses,

112 bance like those seen in patients during the acute phase of IM.

113 f HIV-1 replication during the course of the acute phase of infection and the reactivation of silent

114 ZIKV-reactive T cells in the acute phase of infection are detected earlier and in gre

115 n profound loss of corneal nerves during the acute phase of infection demonstrate increased corneal n

116 e preferential loss of Th17 cells during the acute phase of infection impairs the integrity of the gu

117 ther maternally derived IFN-gamma during the acute phase of infection that is essential for the proge

118 pression of activating FcgammaRIV during the acute phase of infection was also noteworthy.

119 Glucose metabolism also influenced the acute phase of infection when the replicating virus was

120 nor infected, exposed but not infected, pre-acute phase of infection, acute phase of infection, post

121 imates (NHPs) have suggested that during the acute phase of infection, antiviral mucosal immunity res

122 reduced in immunocompromised pigs during the acute phase of infection, but TNF-alpha-specific CD8(+)

123 or Human Immunodeficiency Virus (HIV) during acute phase of infection, initiating an ongoing cascade

124 not infected, pre-acute phase of infection, acute phase of infection, post-acute phase of infection.

125 sitized RBC than infected WT mice during the acute phase of infection, when parasitemia was rapidly r

126 gs continued fecal virus shedding beyond the acute phase of infection, whereas the majority (7/10) of

127 ontrol of TB in nonhuman primates during the acute phase of infection.

128 of infection, acute phase of infection, post-acute phase of infection.

129 ared to that of virions generated during the acute phase of infection.

130 ariety of clinical manifestations during the acute phase of infection.

131 e responses compared to survivors during the acute phase of infection.

132 ines IL-4 and IL-10, particularly during the acute phase of infection.

133 Most complexes might be formed during the acute phase of inflammation and have an effect on the ho

134 les of these cells and chemokines during the acute phase of inflammation in sepsis.

135 In the acute phase of inflammation-(d1), 15-epi-LXA4 primes neu

136 of pediatric msTBI patients during the post-acute phase of injury who have markedly impaired CC func

137 nsive lowering of blood pressure (BP) at the acute phase of intracerebral haemorrhage (ICH) is benefi

138 Conversely, mast cell ablation after the acute phase of IRI had no impact on organ atrophy, tubul

139 ng to combat degeneration of RGCs during the acute phase of LHON have not been very effective.

140 eventing ischemic and bleeding events in the acute phase of myocardial infarction treated with a prim

141 Interestingly, during the acute phase of myocardial ischemia, focal ectopies arisi

142 lysis and reactive new bone formation in the acute phase of osteomyelitis.

143 proinflammatory cytokines determined in the acute phase of PM.

144 ction and reactive bone formation during the acute phase of S. aureus osteomyelitis.

145 rotective and/or reparative role in the post-acute phase of SCI.

146 The acute phase of sepsis is characterized by a strong infla

147 in PB, BM, and ALN T-cell subsets during the acute phase of SIV infection.

148 Inflammation during the acute phase of stroke results in nuclear translocation o

149 mmon use of sedatives and anesthetics in the acute phase of TBI management, their effect on glial cel

150 sponse seem to play a beneficial role in the acute phase of TBI.

151 Our results show that during the acute phase of the 2013-14 floods, potential feeding are

152 tients should start, if possible, during the acute phase of the disease and last more than 1 year.

153 n an HLA-DRB1*11-positive patient during the acute phase of the disease whereas ASYILIRD-positive CD4

154 ces to support the gut microbiota during the acute phase of the disease.

155 thod to detect viral genetic material in the acute phase of the disease.

156 s in the brain that were infected during the acute phase of the infection and survived for approximat

157 t side effects and are only effective in the acute phase of the infection with limited efficacy in th

158 8(+) central memory T cells (TCM) during the acute phase of the primary response that is dominated by

159 nist isoxazole derivative, was tested in the acute phase of Theiler's murine encephalomyelitis virus-

160 presented with red/injected eyes during the acute phase of their illness.

161 of cognitive-behavioral therapy (CBT) in the acute phase of treatment.

162 ions and neuroendocrine symptoms, marked the acute phase of trichodysplasia spinulosa, whereas initia

163 terminals are significantly increased in the acute phase of TTS.

164 The development of FID in the acute phase of type B IMH has a poor prognosis owing to

165 d from the colonic mucosa of patients in the acute phase of UC.

166 , is a rare condition that occurs during the acute phase of urinary obstruction.

167 ls, away from SLECs toward MPECs, during the acute phase of vaccinia virus infection.

168 During the acute phases of S. pneumoniae infection, these populatio

169 Dialysis during the acute phase (P = .01), dialysis duration (P = .01), and

170 , despite broad cognitive dysfunction in the acute phase, patients with VGKC-LE often make a substant

171 Levels of acute-phase peak viral replication were highest in SIVma

172 ociated with a reduction in viremia from its acute-phase peak.

173 f psychotherapy after successful response to acute-phase pharmacotherapy in the treatment of adults w

174 Serum amyloid A (SAA) is an acute-phase plasma protein that functions in innate immu

175 C-reactive protein (CRP), an acute-phase plasma protein, is a major component of infl

176 trally associated with other symptoms in the acute phase, potentially pointing to the utility of addr

177 Acute-phase production of MCP-1 correlated with viremia

178 Importantly, neutralization of acute-phase proinflammatory cytokines in antibiotic-indu

179 repair mechanisms that persist following the acute phase promote inflammation and fibrosis in the chr

180 Here we show that the acute phase protein C-reactive protein (CRP), a ligand f

181 ations as a biomarker for sleep restriction, acute phase protein concentrations and malaria infection

182 ost significantly upregulated factors is the acute phase protein lipocalin-2 (LCN2).

183 also reduced the lipopolysaccharide-induced acute phase protein response (C-reactive protein).

184 ntified as a carboxy-terminal peptide of the acute phase protein serum amyloid A (SAA) 1.

185 Thus, acute-phase protein A1AT is a physiological regulator of

186 The acute-phase protein A1AT is an inducer of hepcidin expre

187 Because the acute-phase protein C-reactive protein (CRP) is highly u

188 LytA prevented binding of C1q and the acute-phase protein C-reactive protein to S. pneumoniae,

189 Acute-phase protein levels on HDL may serve as novel bio

190 The acute-phase protein serum amyloid A (A-SAA) was signific

191 terleukin-6 (IL-6) is the major regulator of acute-phase protein synthesis and one of the most studie

192 We first examined whether the acute-phase protein, alpha-2 macroglobulin (A2M), a majo

193 physiological regulator of angptl4, another acute-phase protein.

194 ME7 animals allow independent measurement of acute phase proteins in the brain and circulation, we ex

195 In liver, they regulate the secretion of acute phase proteins.

196 and endotoxin core IgG antibody [EndoCAb]), acute-phase proteins (alpha-2 macroglobulin [alpha-2M],

197 HDL particles were enriched with acute-phase proteins (serum amyloid A, haptoglobin, and

198 Decreases in circulating plasma markers and acute-phase proteins and an increased baseline effector

199 talyze fluctuations in the concentrations of acute-phase proteins and certain micronutrient biomarker

200 infiltrating Ly6C(pos) macrophages expressed acute-phase proteins and exhibited an inflammatory profi

201 tion and accompanying increases in levels of acute-phase proteins and markers of inflammation and pro

202 e spleen followed by increased production of acute-phase proteins and proinflammatory cytokines.

203 lammation such as inflammatory cytokines and acute-phase proteins are reliably elevated in a signific

204 ables, peak values of 15 cytokines, and nine acute-phase proteins in serum were evaluated as potentia

205 Here, we posit that inflammatory and acute-phase proteins in the circulation increase after O

206 In this context, acute-phase proteins such as Pentraxin-3 (PTX3) are rele

207 Pentraxins are acute-phase proteins that belong to a family of evolutio

208 d levels of microbial translocation markers, acute-phase proteins, and inflammatory markers were all

209 y reduced levels of circulating and airspace acute-phase proteins, exhibited significantly elevated l

210 S and other microbial translocation markers, acute-phase proteins, inflammatory markers, and proinfla

211 lutionarily conserved family of inflammatory acute-phase proteins.

212 ear relation of ferritin concentrations with acute-phase proteins.

213 A small cluster included acute-phase reactant genes (SAA1, SAA2, and SAA2-SAA4).

214 physiological importance of the prototypical acute-phase reactant in the etiology of the disease is u

215 an indicator of functional ID that is not an acute-phase reactant, but challenges in its interpretati

216 Increases in acute phase reactants are typical of polymyalgia rheumat

217 g syndrome (electrolytes and phosphate), and acute phase reactants, and recorded the nutritional ther

218 differential nasal airway response including acute-phase reactants proteins (fibrinogen, haptoglobin

219 ediated damping of the FcepsilonRI-dependent acute-phase reaction.

220 kin 1beta and 6 (IL-1beta, IL-6) mediate the acute phase response (APR).

221 Inflammation was an acute phase response and chronic inflammation, with litt

222 ription factor known to regulate the hepatic acute phase response and energy homeostasis under stress

223 cardial infarction induces activation of the acute phase response and infiltration of leukocytes to t

224 netic risk factors, its association with the acute phase response and its age of onset and female pre

225 hepatocytes is important for control of the acute phase response and regulation of liver regeneratio

226 ne disease often present with a debilitating acute phase response as a result of Vgamma9Vdelta2 T cel

227 The results show activation of the hepatic acute phase response by 2 hours after TBI, hepatic infla

228 flammation-related liver transcripts, mostly acute phase response genes.

229 iological ER stress-induced inflammatory and acute phase response in adipocytes, leading to lower cir

230 tocytes with IL-6, the major mediator of the acute phase response in liver, and characterized acute p

231 implicated in nuclear receptor activations, acute phase response pathway, glutaryl-CoA/tryptophan de

232 ession through Janus kinase 2 (JAK2) and the acute phase response signal transducer and activator of

233 y and repair such as coagulation/thrombosis, acute phase response signaling and complement activation

234 The acute phase response to infection and inflammation induc

235 Initially, NTIS is a consequence of the acute phase response to systemic illness and macronutrie

236 Notably, hypoxia increased expression of the acute phase response transcription factor C/EBPdelta whi

237 ys associated with complement activation and acute phase response.

238 Brain injury elicits a systemic acute-phase response (APR), which is responsible for co-

239 it systemic inflammation and induce a robust acute-phase response (APR).

240 l death, temporally linked with a strong IFN acute-phase response and evidence of gut barrier breakdo

241 ription factor known to regulate the hepatic acute-phase response and lipid homeostasis.

242 ese genes comprise coexpression networks for acute-phase response and pro-inflammatory processes.

243 oprotein, induced at the early stages of the acute-phase response in liver and plasma.

244 le, whereas activin A curbed the IL6-induced acute-phase response in liver.

245 BRINDA investigators found that the acute-phase response is so prevalent that it must be ass

246 y analysis suggests that cerebral immune and acute-phase response may play a role in mediating PaO2 o

247 resent because of confounding effects of the acute-phase response on the interpretation of most iron

248 We found that the acute-phase response proteins serum amyloid A (SAA) 1 an

249 RP) and serum amyloid A (SAA), the prototype acute-phase response proteins, in the context of the var

250 al antiviral factors and pathways (including acute-phase response signaling and complement system) we

251 ion regulates the unfolded protein response, acute-phase response, and DDR in hepatocytes.

252 ent endoplasmic reticulum stress, defects in acute-phase response, and increased hepatocellular damag

253 ia, defective B cell memory, and an impaired acute-phase response, as well as skeletal abnormalities

254 al systemic inflammatory biomarkers, but the acute-phase response, enterocyte turnover, monocyte acti

255 T3 target genes that are associated with the acute-phase response, inflammation, and wound healing.

256 set of genes implicated in proteostasis, the acute-phase response, metabolism, and the DNA damage res

257 n systemic immunity, they are central in the acute-phase response, which floods the circulation with

258 nse to trauma is associated with the hepatic acute-phase response.

259 is a multifunctional protein associated with acute-phase response.

260 or- and nontumor-bearing mice can produce an acute-phase response.

261 cause RBP concentrations decrease during the acute-phase response.We aimed to assess the relation bet

262 er upregulation of interferon signalling and acute phase responses compared to survivors during the a

263 is available about the development of innate acute-phase responses in Lyme disease.

264 transcripts associated with inflammatory and acute-phase responses, coagulative activities, and trans

265 inhibitor, with levels that increase during acute-phase responses.

266 in the Telemedicine Approaches to Evaluating Acute-Phase Retinopathy of Prematurity (e-ROP) Study and

267 The Telemedicine Approaches to Evaluating Acute-Phase Retinopathy of Prematurity (e-ROP) Study tel

268 om the Telemedicine Approaches to Evaluating Acute-Phase Retinopathy of Prematurity (e-ROP) study was

269 elemedicine Approaches for the Evaluation of Acute-Phase Retinopathy of Prematurity (e-ROP) study.

270 om the Telemedicine Approaches to Evaluating Acute-Phase Retinopathy of Prematurity study, conducted

271 om the Telemedicine Approaches to Evaluating Acute-Phase Retinopathy of Prematurity Study.

272 Transcriptional profiling during the acute phase revealed upregulation of genes associated wi

273 the Telemedicine Approaches to Evaluating of Acute-Phase ROP (e-ROP) Study.

274 ommonly after treatment with bevacizumab for acute-phase ROP than after laser.

275 tradicts the prevailing sepsis paradigm that acute-phase sepsis deaths (<5 d) result from excessive i

276 This NPHV infectious clone and resulting acute phase sera will facilitate more detailed studies o

277 Acute-phase serum samples from 346 patients with a suspe

278 ecific MAC-ELISA (NS1-MAC-ELISA) on archived acute-phase serum specimens from patients with confirmed

279 nal lesions and of the optic disc during the acute phase showed no statistically significant differen

280 However, these cells did not impact the acute-phase SIV load after challenge compared to histori

281 ed robust viral replication concomitant with acute-phase symptoms, and provided a model to study the

282 In patients with ischaemic stroke, the first acute-phase systolic blood pressure was much lower than

283 Reversal of anticoagulation during acute phase, systolic BP at 4 hours, and reinitiation of

284 r benefits of early medical treatment in the acute phase than do longer-term trials.

285 Traditionally, research into the hyper-acute phase (the first hour) of disease has been difficu

286 mune signaling and HCV restriction to impact acute-phase-to-chronic-phase transition.

287 Of the 200 participants enrolled in acute-phase treatment, 144 were assigned to continuation

288 ears, but among individuals who survived the acute phase, treatment was associated with a significant

289 side effects (secondary outcomes) with three acute-phase treatments for bipolar II depression.

290 Interestingly, the acute phase variant of C4BP lacking the beta-chain and p

291 e relative hazard of transmission during the acute phase versus the chronic phase (RHacute) and the a

292 e targets gp41 epitopes and fails to control acute-phase viremia.

293 and genetic distances during the hepatitis E acute phase were higher in patients whose infection beca

294 bearing RBC-derived microvesicles during the acute phase, which decreased after recovery.

295 Chagas disease is characterised by an acute phase, which is partially resolved by the immune s

296 oportion of transmission attributable to the acute phase, which would require data on the broader pop

297 the duration and relative infectivity of the acute phase, while accounting for several possible sourc

298 ing new drugs to treat Chagas disease in the acute phase with greater activity, less toxicity, and a

299 se of illness had poor prognosis at the post-acute phase with more restricted joint movement and high

300 mptoms were central to other symptoms in the acute phase, with intrusions and physiological reactivit