ライフサイエンスコーパス: acyclic

1 (the removal of vertices, leaving the graph acyclic).

2 a wide variety of functionalized cyclic and acyclic 1,2-disubstituted alkenes, including simple ally

3 ding olefin metathesis reactions that afford acyclic 1,2-disubstituted Z-alkenyl halides.

4 termolecular addition of aliphatic amines to acyclic 1,3-dienes.

5 Reaction with an acyclic 1,3-diketone yields the corresponding benzo[b]fu

6 Acyclic 1,4-diene products bearing either alkyl- or aryl

7 nzoquinone (DDQ) from 13 C-H hydride donors (acyclic 1,4-dienes, cyclohexa-1,4-dienes, dihydropyridin

8 ffectively promote the Cope rearrangement of acyclic 1,5-dienes bearing a terminal cyclopropylidene.

9 in the biosynthesis of cholesterol) from the acyclic 2,3-oxidosqualene catalyzed by oxidosqualene cyc

10 owever, the addition of enolate derived from acyclic 2-oxo-butanoate 10 to 2H-azirine phosphine oxide

11 f an allenyl vinyl ketone was intercepted by acyclic, 2-silyloxy-substituted butadienes by highly reg

12 The results revealed sets of both cyclic and acyclic 2OG analogues that are FTO inhibitors.

13 ently reported for catalytic alkynylation of acyclic acetals/ketals, and is uniquely enabled by the a

14 The scope of esters encompasses acyclic acetates, propionates, and isobutyrates, alpha-a

15 ic ring-opening of O-heterocycles to provide acyclic alcohols and carboxylic acids with controlled fo

16 with a range of Grignard reagents to furnish acyclic alcohols with high diastereoselectivity.

17 e involving sequential alpha-alkynylation of acyclic aldehydes using hypervalent iodine reagents and

18 nt C-H bond iodination of various cyclic and acyclic alkanes providing iodoalkanes in good yields.

19 ore highly branched products from cyclic and acyclic alkanes.

20 A variety of heterocyclic, carbocyclic, and acyclic alkenes react with good to excellent yields and

21 nctionalized arylated carbonyl products from acyclic alkenol substrates, with excellent enantioselect

22 ative Heck reaction using achiral or racemic acyclic alkenols and boronic acid derivatives is reporte

23 cient processes that can be used to generate acyclic alkenyl halides.

24 (CAAC), acyclic di(amino)carbene (ADAC), and acyclic (alkyl)(amino)carbene (AAAC) give rise to the co

25 the other hand, the modular approach led to acyclic alkyne-functionalized scaffolds of a controlled

26 ereocontrolled synthesis of tetrasubstituted acyclic all-carbon olefins has been developed via a ster

27 ive intermolecular Heck-Matsuda arylation of acyclic allylic alcohols.

28 A variety of cyclic and acyclic allylic carbonates are competent electrophilic p

29 l diphosphate (GPP), to yield a noncanonical acyclic allylic diphosphate product, 2-methylgeranyl dip

30 ytic methods used to access enantioenriched, acyclic alpha,alpha-disubstituted alpha-amino acids with

31 n(0) as a stoichiometric reductant generates acyclic alpha,alpha-disubstituted ketones in good yields

32 ies, such as propargyl or allyl groups, into acyclic alpha,beta,gamma,delta-doubly unsaturated accept

33 enantioselective allylic substitutions with acyclic alpha-alkoxy ketones catalyzed by a metallacycli

34 ed copper(I) enolates generated in situ from acyclic alpha-alkoxy ketones.

35 idates why silylated nucleobase additions to acyclic alpha-alkoxythiacarbenium intermediates proceed

36 ed arylation reaction of chiral, enantiopure acyclic alpha-amino aldehydes enabled by a B/Zn exchange

37 The nature of the kinetic interaction of the acyclic alpha-CNPs against the herpetic DNA polymerases

38 allyl vinyl ether was utilized to afford an acyclic alpha-keto ester building block endowed with fun

39 n) (pin=pinacolato) compounds to ketones and acyclic alpha-ketoesters was developed.

40 Acyclic alphagammaalpha-tripeptides derived from fluorin

41 cale and could be performed with unprotected acyclic amide precursors.

42 and N-acyl-tosylamides (Ts), two classes of acyclic amides that have recently enabled the developmen

43 ployed in the key step for the conversion of acyclic amides to the corresponding tetrahydroisoquinoli

44 antioselective beta-C(sp(3))-H activation of acyclic amides.

45 1, [((TMS) L)ClSi:-->Ni(NHC)2 ], bearing the acyclic amido-chlorosilylene ((TMS) L)ClSi: ((TMS) L=N(S

46 Facile oxygenation of the acyclic amido-chlorosilylene bis(N-heterocyclic carbene)

47 ylamide function in position 3 and cyclic or acyclic amines in position 7 exhibit high antitrypanosom

48 d macrocycle was 60-fold more potent than an acyclic analog.

49 enhancement of up to 100-fold over flexible acyclic analogs was observed presumably due to an entrop

50 Acyclic analogue M-1 contains a terminal olefin as the p

51 ncy of the cyclized compound relative to its acyclic analogue.

52 with the cyclophane reacting faster than its acyclic analogue.

53 icated interesting binding properties of the acyclic analogues.

54 (XB) bis-iodotriazole-pyridinium-containing acyclic and [2]catenane anion host systems are described

55 ntramolecular cyclization and dehydration in acyclic and bicyclic monoallylic diols, a formal S(N)2'

56 cules that comprise stereochemically complex acyclic and conformationally flexible carbon chains make

57 ons (X,Y = O,N) in the "alpha-systems" (both acyclic and constrained within a heterocyclohexane frame

58 In situ derived acyclic and cyclic 1,2-diaza-1,3-dienes (DDs) were engag

59 The scope of the reaction includes both acyclic and cyclic allylic boronic esters which lead to

60 Acyclic and cyclic alpha,beta-unsaturated ketones, as we

61 CN bond formation which directly introduces acyclic and cyclic amines to the alpha-position of phosp

62 ce hydrogenolysis rates and selectivities of acyclic and cyclic C2-C8 alkanes on Ir, Rh, Ru, and Pt c

63 onstrated by transforming them into valuable acyclic and cyclic compounds (including pharmacologicall

64 tioselective C-C bond-forming reactions with acyclic and cyclic enones, thereby converting these read

65 nient one-pot procedure for the synthesis of acyclic and cyclic guanidines mediated by the Ph3P/I2 sy

66 e various alcohol-derived P2 carbamates with acyclic and cyclic heteroatomic functionalities into the

67 d and predictable assembly of complex chiral acyclic and cyclic nitrogen-containing motifs in one pot

68 ophores, the amino donors are varied between acyclic and cyclic while the alkoxy donors are varied in

69 cyclic allylic boronic esters which lead to acyclic and exocyclic tetrasubstituted homoallylic alcoh

70 hat allow the synthesis of a wide variety of acyclic and heterocyclic small molecules.

71 s acid promoted cascade cyclizations of both acyclic and macrocyclic alkynones is described.

72 For both acyclic and macrocyclic alkynones, high diastereoselecti

73 is protocol is applicable to both cyclic and acyclic aryl ketones.

74 cted trifluoromethyl aldimines and cyclic or acyclic beta-keto esters bearing different ester residue

75 , and enantioselective allylic alkylation of acyclic beta-ketoesters to form vicinal tertiary and all

76 ce) yielded five phenolic compounds, one new acyclic bis phenylpropanoid (1) and four previously know

77 esis, metalation, and redox properties of an acyclic bis(iminothienyl)methene L(-) are presented.

78 Pioneering work revealed that acyclic boronic acids can act as 'transition state analo

79 ihydropyrans and 3,4-dehydropiperidines from acyclic building blocks in good yields without using any

80 lver-catalyzed hydroarylation of arynes from acyclic building blocks with unactivated arenes in intra

81 The application of acyclic C2-symmetric chelating bis-sulfoxide ligands in

82 onship through the preparation of cyclic and acyclic C4-disubstituted analogs of 1, leading to the id

83 o-n-butadienes and flexible sigma-cyclic, pi-acyclic carbo-cyclohexadienes, and to "pro-aromatic" con

84 en considered, i.e. freely rotating sigma,pi-acyclic carbo-n-butadienes and flexible sigma-cyclic, pi

85 The preparation of acyclic, carbocyclic and azacyclic alpha-aminoboronic ac

86 selective boron-aldol reaction to afford the acyclic carbon skeleton of the methylenecylopentane moie

87 mination reactions, we have studied a set of acyclic carbonyl substrates that react by an irreversibl

88 The naphthalene-walled acyclic CB[n] container is able to extract large hydroca

89 The acyclic CB[n]-type containers generally display signific

90 of the aromatic sidewalls on the ability of acyclic CB[n]-type molecular containers (1a-1e) to act a

91 bles catalytic enantioselective formation of acyclic CF3-bearing all-carbon quaternary stereocenters

92 A bifunctional derivative of the versatile acyclic chelator H4octapa, p-SCN-Bn-H4octapa, has been s

93 perform the synthesis of specific cyclic and acyclic chiral moieties.

94 hydrogen-bonded molecular complex comprising acyclic components, namely, a stoppered thread (1) with

95 ws the construction of cyclic syn-ketols and acyclic compounds with multiple contiguous stereocenters

96 ter cross-linking agents and cytotoxins than acyclic conjugates.

97 es made with the macrocyclic acceptor and an acyclic control molecule; we find that the superior perf

98 rocycle substructures were superior to their acyclic counterparts.

99 The ability of two water-soluble acyclic cucurbit[n]uril (CB[n]) type containers, whose h

100 We report that acyclic cucurbit[n]uril molecular containers 1 and 2 sel

101 the inverted "U" shaped conformation of the acyclic DAPs is a preferred bioactive conformation.

102 ed for a homologous macrocyclic dimer and an acyclic derivative of pyromellitic diimide (PMDI).

103 cyclopropanes which can be transformed into acyclic derivatives bearing one or multiple tertiary or

104 r-NHC), cyclic (alkyl)(amino)carbene (CAAC), acyclic di(amino)carbene (ADAC), and acyclic (alkyl)(ami

105 a cyclic (alkyl)(amino)carbene (CAAC) and an acyclic diaminocarbene (ADAC), are able to undergo inser

106 Computed descriptors for acyclic diaminocarbene ligands are developed in the cont

107 ular approach of substrates to carbenes from acyclic diazo precursors may be relatively slow due to a

108 employed as main-chain functional groups in acyclic diene metathesis (ADMET)-polymers, conferring du

109 rgyl and 2-boryl-substituted allyl groups to acyclic dienoates with high selectivity.

110 clic carbene catalyzed cycloisomerization of acyclic dienyl esters to cyclohexyl beta-lactones.

111 oyed in the stereoselective synthesis of the acyclic dienyl moiety of the target molecule.

112 wide range of 2-iodo-N-phenyl benzamides and acyclic diketones as starting materials were investigate

113 s keto-esters or keto-sulfones and cyclic or acyclic diketones, afforded more than 30 2,3,5,6-tetrasu

114 Racemic acyclic diols as well as trans-cycloalkane-1,2-diols wer

115 exes are found to be more stable, while with acyclic disilylstannylenes the Ni(0) stannylene complex

116 gene-metabolite associations involved in the acyclic diterpene glucoside pathway after selectively ex

117 trimerizations of 1,6-diynes with cyclic and acyclic double bonds.

118 fuller understanding of the chemistry of the acyclic (E)-diazeniumdiolates.

119 the enone products provides rapid access to acyclic enantiomerically enriched alpha,alpha'-dialkyl-s

120 s to a variety of asymmetrically substituted acyclic enediynes fused to heterocycles.

121 ained as single diastereomers from cyclic or acyclic enol ethers and styrenes.

122 Cyclic and acyclic enones as well as alpha,beta-unsaturated aldehyd

123 udies on this family of reactions, employing acyclic enones, 5-15-membered cyclic enones, and alpha-b

124 lytic, asymmetric alpha-functionalization of acyclic esters constitutes a significant challenge in th

125 c alpha,beta-unsaturated ketones, as well as acyclic esters, Weinreb amides, and aldehydes, can serve

126 alytic asymmetric alpha-functionalization of acyclic esters.

127 Among the acyclic ethane-bridged bis-sulfoxides tested, the ligand

128 The direct alpha-arylation of cyclic and acyclic ethers with heteroarenes has been accomplished t

129 alpha-oxy C(sp(3))-H arylation of cyclic and acyclic ethers.

130 tionally stable at low temperature, even for acyclic examples.

131 The methodology enables the formation of acyclic fluorine-containing compounds in good yields wit

132 he levels of diastereoselection generated in acyclic free-radical processes.

133 The application of stereochemically defined acyclic fully substituted enolates of ketones to the ena

134 Recognizing that ontologies are a directed acyclic graph (DAG) of terms and hierarchical relations,

135 ng a set of sampled alignments as a directed acyclic graph (DAG) whose nodes are alignment columns; e

136 ctions, and they take the form of a directed acyclic graph (DAG).

137 s from the alignments, it defines a directed acyclic graph and maps the transfrags to paths on the gr

138 Using a directed acyclic graph framework, we defined six causal scenarios

139 fication is described in terms of a directed acyclic graph in which nodes form a complex network of m

140 escribed by a tree but is instead a directed acyclic graph known as a phylogenetic network.

141 g of the data-generating mechanism, directed acyclic graph models should be avoided because causal re

142 aph motifs, indicating recurrent wiring, and acyclic graph motifs, indicating feedforward wiring.

143 random walks with restart on the GO directed acyclic graph, along with the available functions of a p

144 curate preassembled reads through a directed acyclic graph-based consensus procedure, which we follow

145 nfounders that were identified in a directed acyclic graph.

146 analyses with the help of a generic directed acyclic graph.

147 arities were conceptualized using a directed acyclic graphic.

148 analytic methods and tools such as directed acyclic graphs (DAGs) and Bayesian statistical technique

149 Directed acyclic graphs (DAGs) are nonparametric graphical tools

150 the Markov equivalence class of the directed acyclic graphs (DAGs) in a genetical genomics analysis f

151 These models are represented as directed acyclic graphs (DAGs) of collections of 'selectivity' re

152 Directed acyclic graphs (DAGs) were introduced into epidemiology

153 Directed acyclic graphs (DAGs) were used to explore the structura

154 We used directed acyclic graphs and the example of bone lead and mortalit

155 In this paper, we use directed acyclic graphs to characterize potential biases in studi

156 for generalizability and use causal directed acyclic graphs to show how these assumptions might play

157 Directed acyclic graphs were used to identify potential confounde

158 l inference methods (in particular, directed acyclic graphs), they describe different threats to the

159 o classes of models: 1) multi-level directed acyclic graphs, and 2) interdependent coupled networks.

160 as collider-stratification bias in directed acyclic graphs, but it is difficult to anticipate the ma

161 as can be guided using tools such as direct acyclic graphs.

162 nd an optimized doubly anthracene-terminated acyclic Hamilton-like receptor (2b), leads to an interlo

163 The acyclic hexapeptide precursor to natural product segatal

164 fashion and is demonstrated with cyclic and acyclic homoallylic and bishomoallylic alcohol substrate

165 llization, and solid state photochemistry of acyclic, homochiral, hexasubstituted (+)-(2R,4S)-2-carbo

166 ws that the cyclization loop, not present in acyclic homologues, facilitates potent trypsin inhibitor

167 of gas-phase enthalpy of formation of cyclic/acyclic hydrocarbons and amines.

168 The [n]dendralenes are a family of acyclic hydrocarbons which, by virtue of their ability t

169 es of the plants, and recently characterized acyclic hydroxygeranyllinalool diterpene glycosides (HGL

170 Herein, we report a highly reactive acyclic iminosilylsilylene 1, which readily performs an

171 Acyclic inhibitors with achiral serinol groups as the ri

172 5 at the Michael acceptors with formation of acyclic intermediates, which subsequently cyclize to giv

173 -cyclic products to <50% while increases the acyclic isomer selectivity to 38.6%.

174 se conversion of methylcyclopentane (MCP) to acyclic isomer, olefins, cyclohexane, and benzene.

175 each pair of which contains a cyclic and an acyclic isomer.

176 ne was the dominant product with olefins and acyclic isomers as minor products.

177 clohexane and benzene, respectively) without acyclic isomers products.

178 ethyltransferase discovered that modifies an acyclic isoprenoid diphosphate, geranyl diphosphate (GPP

179 cyclopentanes+alkylcyclohexanes > cyclic and acyclic isoprenoids.

180 Both cyclic and acyclic ketones can be mono-alpha-alkylated with simple

181 The asymmetric alkylation of acyclic ketones is a longstanding challenge in organic s

182 Enolizations of highly substituted acyclic ketones used in the syntheses of tetrasubstitute

183 etones with different ring-sizes, as well as acyclic ketones, can be directly arylated at the beta-po

184 nsaturated lactone, and the most challenging acyclic ketones, is reported.

185 for a variety of unsymmetrically substituted acyclic ketones.

186 is protocol is applicable to both cyclic and acyclic ketones.

187 An acyclic lead compound, containing an ether-linked isopro

188 The first group consisted of acyclic (linalool/linalyl acetate) chemotypes with a pre

189 and aza-silyl-Prins reactions, starting from acyclic materials, are reported.

190 e synthesis of many of the small yet complex acyclic members of this family.

191 ergoing facile one-electron oxidation to the acyclic, metal-free, neutral radical L(.) on reaction wi

192 Methyl as well as cyclic and acyclic methylene groups can be activated.

193 and modular protocol for the preparation of acyclic molecular frameworks containing newly created qu

194 e have prepared the macrocycles 8-12 and the acyclic molecules 13-16, incorporating two central triet

195 nt the missing link between nitrogen bearing acyclic molecules and prebiotic nucleobases along with v

196 stereoselective assembly of amine-containing acyclic molecules.

197 e extent that halide recognition by a simple acyclic mono-charged receptor is achievable.

198 ly proposed syn-oxypalladation mechanism for acyclic monoallylic diols, calculations and experiments

199 l characterization of an extensive series of acyclic, monomeric tetrylene dichalcogenolates of formul

200 The acyclic monoterpene alcohol linalool is one of the most

201 rect and rapid access to tetrahydropyrans in acyclic neopeltolide intermediates, a transannular strat

202 Our algorithm implements a directed acyclic network that reconstructs the complex behavioral

203 we report on the first examples of isolable acyclic, neutral, three-coordinate silanones 2 with inde

204 A long-term dream comes true: An acyclic, neutrally charged silanone at last!

205 ll the mechanistic gaps missing leading from acyclic nitrogen-bearing molecules via pyridine to NPAH-

206 vestigation of glycol nucleic acid (GNA), an acyclic nucleic acid analogue, as a modification of siRN

207 Acyclic nucleoside analogues used in this study were ide

208 Acyclic nucleoside bisphosphonates (ANbPs) have previous

209 ynthesized and evaluated several alkoxyalkyl acyclic nucleoside phosphonate diesters and identified o

210 Here, newly synthesized acyclic nucleoside phosphonates (ANPs) have been shown t

211 Acyclic nucleoside phosphonates (ANPs) that contain a 6-

212 The aza-acyclic nucleoside phosphonates (aza-ANPs) are good inhi

213 the ProTide approach applied to a series of acyclic nucleosides aimed at the identification of novel

214 Acyclic nucleosides containing a 3-fluoro-2-(phosphonome

215 lecular [2+2] dimerization reaction of these acyclic olefins to construct cyclobutanes in a highly re

216 ow that hydroarylations occur with internal, acyclic olefins to yield linear alkylarene products.

217 eveloped to access a diversity of cyclic and acyclic oligosaccharide analogues designed as prefunctio

218 -oligomers were characterized to take either acyclic or cyclic molecular structures, depending on the

219 d successfully after assembling a variety of acyclic or cyclic monoketones with prenyl ether-tethered

220 y rate, in all the cases tested that include acyclic or cyclic networks of 10, 30 and 300 genes.

221 Using simulated directed acyclic or cyclic networks, the SML performance is compa

222 ituted alkenyl-, 1,1-disubstituted alkenyl-, acyclic, or heterocyclic trisubstituted alkenyl groups m

223 bond is exocyclic or the compound itself is acyclic, ozonolysis produces less ELVOC and the role of

224 600 times more potent than the corresponding acyclic peptide.

225 Ia inhibitors was designed based on our lead acyclic phenyl imidazole chemotype.

226 oselectivities obtained in the reductions of acyclic phosphine oxides and sulfides by different chlor

227 nal dispositions of their PMDI units and the acyclic PMDI derivative, we identified noticeable change

228 i) 1.60-1.95 and 2.37 V for oxidation of the acyclic PMDI derivative.

229 yntheses are the first of any members of the acyclic polyhalogenated Plocamium monoterpenes and permi

230 actions provide new methods for synthesis of acyclic polyketide analogs with complex stereochemical a

231 lication to stereoselective synthesis of the acyclic portion of antifungal agent plakinic acid A, con

232 o bring together and fuse the two ends of an acyclic precursor such as an alkene (also known as an ol

233 of this hitherto elusive cyclic species from acyclic precursors in a single-collision event.

234 arin framework are constructed starting from acyclic precursors.

235 ularly substituted trans-fused decalins from acyclic precursors.

236 diastereoselectivity from readily available acyclic precursors.

237 Feeding acyclic previridicatumtoxin to Saccharomyces cerevisiae

238 cular Heck reaction of alkenyl triflates and acyclic primary or racemic secondary alkenols.

239 ic nickel-catalyzed ring-opening affords the acyclic product.

240 The optimized conditions afford the desired acyclic products embedding a methyl-aryl quaternary carb

241 In addition, cyclic and acyclic products generated during fatty acid metabolism

242 ng with olefins to construct both cyclic and acyclic products, respectively.

243 An acyclic pyrimidine analogue, containing a five-member cy

244 tioselective methods for the construction of acyclic quaternary carbon stereocenters from achiral or

245 ms have been documented, the construction of acyclic quaternary carbon stereocenters with control of

246 ovides a novel approach for the synthesis of acyclic quaternary carbon stereogenic centers and it rep

247 vides a new approach toward the synthesis of acyclic quaternary carbon stereogenic centers and provid

248 tally novel approach toward the synthesis of acyclic quaternary-substituted alpha,beta-unsaturated ke

249 logy has been developed for the synthesis of acyclic quaternary-tertiary motifs with full control of

250 on on C(1)-C(5) and C(1)-C(6) cyclization of acyclic quinoxalenediynes.

251 lective strategy which incorporates a single acyclic reaction based on the initial stereocenter by me

252 The XB acyclic receptor displays selectivity for acetate over h

253 pared to the analogous hydrogen-bonding (HB) acyclic receptor.

254 ve inspired us to design new macrocyclic and acyclic receptors, which were expected to form strong 1:

255 led interactions between substituents on the acyclic reference molecules.

256 -homodesmotic approach that minimizes use of acyclic references and ensures cancellation of intramole

257 hyl group in biasing the conformation in the acyclic region of the molecule.

258 H-CO-], levels of preorganization (cyclic vs acyclic residues), and stereochemistries, and the helix

259 Clinical studies suggest that the oral acyclic retinoid Peretinoin may reduce the recurrence of

260 l assays, we describe our efforts to develop acyclic scaffold-hops from GSK-690 (1).

261 Adding cycles to the acyclic scale-free graph increases cooperation when mult

262 otocol for efficient additions of cyclic and acyclic secondary alkyl amines to a wide range of alkyl

263 It has been found that the acyclic series of Gd MRI contrast agents are degraded mu

264 A highly asymmetric vinylogous addition of acyclic silyl enol ethers to siloxyvinyldiazoacetate is

265 bulky m-terphenyl ligand, including two new acyclic silylenes) are described.

266 ight: a one-pot, single-step synthesis of an acyclic silylsilylene, Si{Si(SiMe(3))(3)}{N(SiMe(3))Dipp

267 rcise that provided additional insights into acyclic stereocontrol during stereochemically complex fr

268 ramolecular Zweifel-type olefination enabled acyclic stereocontrol to be transformed into cyclic ster

269 s synthesis and allow further development of acyclic strategies for the synthesis of novel nucleoside

270 composition of metal clusters or the cyclic/acyclic structure of the reactants.

271 rrespective of alkane size (C2-C8) or cyclic/acyclic structure.

272 onal and structural diversity from a trivial acyclic substrate with no stereogenic centers.

273 For acyclic substrates a high syn diastereoselectivity (dr >

274 esence of such a directing group, a range of acyclic substrates underwent fluorination to afford high

275 ic centers in a single step from achiral and acyclic substrates.

276 ion of several new carbon-carbon bonds in an acyclic system and in a single-pot operation from simple

277 In an acyclic system, 1,3-trimethylsilyl migration successfull

278 stituted carbenes contrasts with that of the acyclic system.

279 finity for the enzyme when compared with the acyclic system.

280 only just beginning to be realized in simple acyclic systems.

281 alpha-oxy sp(3) C-H bonds in both cyclic and acyclic systems.

282 plausible biosynthetic relationship between acyclic tatanan A and spirocyclic tatanans B and C is pr

283 sources, including aromatic amino acids and acyclic terpenes, suggesting a reduction of metabolic fl

284 yxo, arabino, and xylo) efficiently afforded acyclic thioacetals with high S(N)2-like selectivity at

285 been synthesized by SN2-like cyclizations of acyclic thioaminal precursors.

286 The acyclic thioaminals formed undergo intramolecular cycliz

287 method for the stereoselective synthesis of acyclic thioesters bearing adjacent quaternary and terti

288 The union of SnAP reagents and acyclic trifluoromethylketones yields alpha-CF3 morpholi

289 e study that details the synthesis of stable acyclic trisubstituted [3]dendralenes and deciphers thei

290 ethods for the stereoselective generation of acyclic trisubstituted alkenes in either the E or the Z

291 Heck reaction between alkenyl triflates and acyclic trisubstituted alkenols of varying chain-lengths

292 n to the problem of ECA of alkenyl groups to acyclic trisubstituted enones, an advance achieved by ad

293 synthesis and characterization of a stable, acyclic two-coordinate silylene, Si(SAr(Me(6)))(2) [Ar(M

294 the first reported room temperature stable, acyclic, two-coordinate N,O-silylene 7 exhibiting a fasc

295 y contribute to antioxidant potential whilst acyclic unsaturated oxygenated monoterpenes (e.g. linalo

296 enues of research using cyclotides and their acyclic variants in crop protection.

297 All hitherto reported cyclotides and their acyclic variants were isolated from dicot plants of the

298 in the XB [2]catenane, in comparison to the acyclic XB receptor, due to the interlocked host's uniqu

299 ion of the macrocycle reveals or conceals an acyclic, yet still highly effective, chiral organocataly

300 mical transformations that directly generate acyclic Z allylic alcohols, including products that cont