ライフサイエンスコーパス: acylglycerol

1 ous glycerol became the major contributor to acylglycerols.

2 nd should be generally applicable to other 2-acylglycerols.

3 e reaction involving glycerol 3-phosphate, 1-acylglycerol 3-phosphate, and dihydroxyacetone phosphate

4 eparation necessary to isolate the labeled 2-acylglycerol [(3)H]2-AG resulted in only 4% of the rearr

5 cids arising from the dephosphorylation of 1-acylglycerol-3-P followed by the deacylation of monoacyl

6 glycerol acetyltransferase 1), and Agpat3 (1-acylglycerol-3-phospate O-acyltransferase 3), and lipoly

7 The effects of overexpression of 1-acylglycerol-3-phosphate acyltransferase (AGAT)-alpha, w

8 The 1-acylglycerol-3-phosphate acyltransferase 1 haplotypes we

9 Loss-of-function mutations in 1-acylglycerol-3-phosphate O-acyltransferase (AGPAT) 2 in

10 AGPAT6 is a member of the 1-acylglycerol-3-phosphate O-acyltransferase (AGPAT) famil

11 patic insulin resistance in mice that lack 1-acylglycerol-3-phosphate O-acyltransferase 2 (AGPAT2).

12 nt mutations of the gene (AGPAT2) encoding 1-acylglycerol-3-phosphate O-acyltransferase 2 in 20 affec

13 5-AzaC also strongly induced expression of 1-acylglycerol-3-phosphate O-acyltransferase 9 (AGPAT9) an

14 rms for the same enzymes, specifically for 1-acylglycerol-3-phosphate O-acyltransferases (AGPATs), ha

15 Mutations in the 1-acylglycerol-3-phosphate-O-acyltransferase 2 (AGPAT2) ge

16 Eight different genetic loci, including 1-acylglycerol-3-phosphate-O-acyltransferase 2, Berardinel

17 phospholipid antigen contained a C18:0 lyso-acylglycerol, a C16:0-acylated inositol, and an unsubsti

18 Acylglycerols (AGs) rich in n-3 were produced by extract

19 results present high resolution data on the acylglycerol and cholesterol ester species that were aff

20 uantitation of fatty acid acyl chains in the acylglycerol and FFA portions.

21 k, the effect of the main precursors, namely acylglycerols and chlorinated compounds, on the formatio

22 temporary storage of neutral lipids such as acylglycerols and steryl esters.

23 r colipase with a diacylphosphatidylcholine, acylglycerols, and free fatty acid was investigated by m

24 ospectroscopy allowed us to locally identify acylglycerols as the main constituents of the pattern di

25 ult that both hydrolyzed fatty acids and the acylglycerol backbone are re-esterified to form TG.

26 osphorylates diacylglycerol, ceramide, and 1-acylglycerol but not sphingosine.

27 hese data, we conclude that the acylation of acylglycerols by DGAT1 is important for dietary fat abso

28 d TG resynthesis, occurring because released acylglycerols cannot be used for phospholipid synthesis.

29 lycerols (SQDGs), sphingolipids, di- and tri-acylglycerols (DAGs and TAGs), and sterol derivatives.

30 hesis of glycogen and the glycerol moiety of acylglycerols in skeletal muscle of animals with high pl

31 to incorporation into the glycerol moiety of acylglycerols in the liver.

32 alysis of five lipids (4 phospholipids and 1 acylglycerol) in complex mixtures using MALDI-TOF-MS wit

33 glyceride species (alkyl, acyl- and alkenyl, acylglycerols) in rat mesangial cells, a smooth muscle-l

34 undance of non-chlorinated compounds, namely acylglycerols, in the first stages of the treatment sugg

35 The analyses pointed to acylglycerol kinase (AGK) and general transcription fact

36 inase receptor, type 3 (NTRK3) and fusion of acylglycerol kinase (AGK) with BRAF.

37 rization of a novel lipid kinase, designated acylglycerol kinase (AGK), that phosphorylates monoacylg

38 ncodes a functional DGAT and that changes in acylglycerol lipid metabolism disrupt normal egg chamber

39 found in vitro that they are nucleated at an acylglycerol lipid-water interface.

40 This dovetails with evidence that acylglycerol lipids are involved in hemozoin nucleation

41 al lines of evidence point to involvement of acylglycerol lipids in the nucleation process.

42 s hydrolysis (forskolin) suggesting a shared acylglycerol-mediated mechanism.

43 through short path distillation (SPD) of an acylglycerol mixture (containing 67% MAGs) produced by e

44 roductive cell signaling; interaction by the acylglycerol moiety of GPIs is also required.

45 t in rat adipocytes, probably by hydrolyzing acylglycerols or acyl-CoA esters to the respective free

46 epatic lipogenesis, the glycerol backbone of acylglycerols originates from one of three sources: gluc

47 cyltransferase), and plsC (yhdO) (acyl-ACP:1-acylglycerol-phosphate acyltransferase) function in phos

48 nvolve TG-derived acyl groups rather than an acylglycerol precursor.

49 Partial acylglycerols showed greater ability, than did triacylgl

50 cylation activity at the level of acyl-CoA:1-acylglycerol-sn-3-phosphate acyltransferase.

51 stingly, the presence of ascorbic acid in an acylglycerol structure protected alpha-tocopherol agains

52 sts of a number of stereo- and regioisomeric acylglycerols, their components remain challenging analy

53 d the acyl-CoA independent transacylation of acylglycerols, thereby facilitating energy mobilization

54 amily that possesses triglyceride lipase and acylglycerol transacylase activities.

55 psilon, iPLA2zeta, and iPLA2eta also possess acylglycerol transacylase activity utilizing mono-olein

56 ese results identify three novel TAG lipases/acylglycerol transacylases that likely participate in TA

57 ats, and the glycerol moiety from hydrolyzed acylglycerols was analyzed by (13)C NMR.

58 ch substrate source to glycerol in rat liver acylglycerols was determined using (13)C-enriched substr

59 trate to glycogen and the glycerol moiety of acylglycerols was evaluated.

60 of hemozoin, was consistently induced at an acylglycerol-water interface via their {100} crystal fac