ライフサイエンスコーパス: adaptive

1 ck and domed - that have been proposed to be adaptive.

2 DMs that ultimately mediates said innate and adaptive allergic responses is poorly understood.

3 Although both adaptive and conventional deep brain stimulation suppres

4 nforms topics as different as human history, adaptive and deleterious variation, morphological develo

5 ximity, attachment and belonging may have an adaptive and evolutionary value in terms of survival and

6 the duodenal mucosa as a consequence of both adaptive and innate immune responses to undigested gliad

7 ariation were correlated, respectively, with adaptive and neutral genetic variation.

8 that GR-mediated antiandrogen resistance is adaptive and reversible due to regulation of GR expressi

9 se thermodynamic theory to study an emergent adaptive animal behaviour.

10 X or OX/IND-MSNP induce effective innate and adaptive anti-PDAC immunity when used in a vaccination a

11 SOCS2 limits adaptive anti-tumoral immunity and DC-based priming of T

12 as a demonstrated role in shaping innate and adaptive antiviral immunity by inducing the expression o

13 neration of molecular materials with active, adaptive, autonomous, emergent and intelligent behavior.

14 to reality due to a recent discovery of the adaptive bacterial immune system, which is based on clus

15 Furthermore, the tunability of adaptive behavior differs between TRNs and ERNs.

16 on of innate defensive responses toward more adaptive behavioral responses to threatening stimuli.

17 ition associated with impaired cognitive and adaptive behaviors.

18 : Animals process multimodal information for adaptive behavioural decisions.

19 for our current understanding of healthy and adaptive brain processing.

20 EZH2 was required for proper development of adaptive, but not innate, lymphoid cells.

21 heterogeneous, GBM tumour cells exhibit high adaptive capacity to targeted molecular therapies owing

22 e differentiation and function of innate and adaptive cell types.

23 Adaptive cellular immunity is initiated by antigen-speci

24 Adaptive cellular responses are often required during wo

25 c heritable plasticity that could facilitate adaptive change.

26 en H3N8 and H3N2 CIVs might be the result of adaptive changes acquired during long-term circulation o

27 Rapid adaptive changes can result from the drastic alterations

28 Interestingly, the adaptive changes in RBF206 Vpu are distinct from those f

29 Although mutations distinct from the adaptive changes observed in group M Vpus (M-Vpus) were

30 nectivity pattern of afferented EVC suggests adaptive changes that might enhance the visual processin

31 s identified that is now used to investigate adaptive closed-loop stimulation in first studies.

32 There is no support for the adaptive coevolution of the Galpha:RGS protein pair base

33 A single amino acid substitution-based adaptive coevolution of the Galpha:RGS proteins was prop

34 s a central role in establishing complex and adaptive cognitive and behavioral processing.

35 ion of left sensorimotor circuits, during an adaptive cognitive state, can unmask latent plastic pote

36 Commercial adaptive cognitive training appears to have no benefits

37 Adaptive collective systems are common in biology and be

38 xtents of intensively managed land limiting 'adaptive' community reorganization in response to climat

39 new method: Genomic Mediation analysis with Adaptive Confounding adjustment (GMAC).

40 d new insights into the molecular mechanism, adaptive consequences, and evolutionary history of memor

41 a selective effect on burst duration during adaptive deep brain stimulation, whereas conventional de

42 tem, were randomly assigned using a Bayesian adaptive design to receive either azacitidine 75 mg/m(2)

43 In contrast, AptRank utilizes an adaptive diffusion mechanism to improve the performance

44 a indicate how harnessing a conformationally adaptive dimer can drive large-scale cargo movement with

45 Explaining the maintenance of adaptive diversity within populations is a long-standing

46 Autonomously adaptive dosing algorithms used data from a continuous g

47 associated receptor overexpression, would be adaptive during glioma evolution.

48 g that DNA methylation constitutes a rapidly adaptive epigenetic mark.

49 tion size appears to have allowed for faster adaptive evolution and removal of harmful mutations, dri

50 We identified strong signatures of adaptive evolution at multiple sites along the spectrin-

51 This work emphasizes the speed at which adaptive evolution can yield enzymes with sufficiently h

52 se H. pylori subpopulations, in which BabA's adaptive evolution contributes to H. pylori persistence

53 ate are theorized to play different roles in adaptive evolution depending on the fitness landscape; h

54 Unraveling the mechanisms of microbial adaptive evolution following genetic or environmental ch

55 nus Camelus is an interesting model to study adaptive evolution in the mitochondrial genome, as the t

56 iors and ecology is key to understanding the adaptive evolution of locomotion.

57 capacity of this asexual snail to spread by adaptive evolution or plasticity to different environmen

58 and establish in novel environments through adaptive evolution, resulting in devastating effects on

59 Using adaptive evolution, we obtained a mutant of Escherichia

60 luding epigenetic inheritance, contribute to adaptive evolution.

61 that selection could act on and facilitating adaptive evolution.

62 the question of whether this contributes to adaptive evolution.

63 Here, through adaptive evolutionary analyses of phototransduction gene

64 These studies reveal an adaptive feedback mechanism in tyrosine kinase-driven ca

65 ly enhance or suppress neuronal function for adaptive feedback-loop applications in the future.

66 However, whilst limb loss is unlikely to be adaptive, females with missing limbs may play a role in

67 Adaptive filtering has been established previously for c

68 pecifically, present-oriented behaviours are adaptive for young people (e.g., in terms of mating and

69 ic homeostatic plasticity, a fundamental and adaptive form of NMJ plasticity in which perturbation to

70 For this purpose, we present an adaptive gene-based test and a pathway-based test for as

71 pensate for these developmental constraints (adaptive growth plasticity).

72 Our study reconstructs the genetic and adaptive history of a neglected episode of the African D

73 rovided new insight into the demographic and adaptive history of our species, Homo sapiens, including

74 e ageing process is a significant decline in adaptive homeostasis capacity.

75 Adaptive homeostasis enables biological systems to make

76 However, the mechanisms responsible for such adaptive homeostasis remain largely unknown.

77 However, CPS-specific adaptive humoral immune responses can only be achieved b

78 Despite adaptive immune cell infiltration in claudin-low tumors,

79 Innate and adaptive immune cells modulate heart failure pathogenesi

80 nvolves a coordinated response of innate and adaptive immune cells working in concert, with many feed

81 ed wide-ranging effects of AES on innate and adaptive immune compartments.

82 ynurenine/tryptophan (KT) ratio, a marker of adaptive immune defects, strongly predicts mortality dur

83 ersistent viral replication independently of adaptive immune effector functions.

84 ination therapies recruiting both innate and adaptive immune effectors to eradicate established tumor

85 expanded our understanding of the innate and adaptive immune mechanisms that protect against ubiquito

86 terial responses by reprogramming innate and adaptive immune mechanisms.

87 Moreover, because we capture adaptive immune memory and the impact of transplantation

88 are important for survival in the context of adaptive immune pressure and for nonreplicating persiste

89 features of epitope-specific repertoires and adaptive immune recognition.

90 tory cytokine induction by SVLP(+) DCs, with adaptive immune response activation ex vivo/in vivo.

91 a protozoan parasite that evades its host's adaptive immune response by repeatedly replacing its den

92 to assess whether the carbohydrate-specific adaptive immune response exemplified in our previous stu

93 pe I IFN response, suggesting a role for the adaptive immune response in resolving infection.

94 This change in the adaptive immune response is associated with impaired vir

95 The adaptive immune response is regulated primarily by mecha

96 , the memory component of the virus-specific adaptive immune response may improve viral control compa

97 B cells are a major part of the adaptive immune response to inhaled HDM allergen, partic

98 ough IFNgamma is the central mediator of the adaptive immune response to pathogens, it has been shown

99 er, this therapy recruits both an innate and adaptive immune response, as deficiencies in either arm

100 ttern recognition receptors in informing the adaptive immune response, markedly less attention has be

101 n SHRs represent an abnormal proinflammatory adaptive immune response.

102 disease pathology, overriding the protective adaptive immune response.

103 vading pathogens but also for initiating the adaptive immune response.

104 te immune properties to limit an exaggerated adaptive immune response.

105 ect in cell to cell communication during the adaptive immune response.

106 high-affinity T-cell receptors to deepen the adaptive immune response; and reinvigorating older appro

107 crophage infiltration initiates long-lasting adaptive immune responses after TBI.

108 d cytotoxic CD8+ T cells are key players for adaptive immune responses against acute infections with

109 mune cells, mechanisms of their synergy with adaptive immune responses against tumors, and discuss re

110 that lymphadenectomy impairs acquisition of adaptive immune responses and antibody production in res

111 global knockout of PLD4 modulated innate and adaptive immune responses and attenuated the upregulatio

112 Adaptive immune responses are tailored to different type

113 In patients with CHB, both innate and adaptive immune responses are weak and thus rarely lead

114 FN response of mice was suppressed, then the adaptive immune responses became critical.

115 More broadly, they suggest that adaptive immune responses can contribute to innate IEL a

116 re an important site at which the innate and adaptive immune responses converge but their architectur

117 Augmentation of adaptive immune responses during therapy was more impres

118 le of HIV-specific CD4(+) T cells in shaping adaptive immune responses in individuals infected with c

119 L-33 plays critical roles in both innate and adaptive immune responses in mucosal organs.

120 s also capable of modulating host innate and adaptive immune responses in response to sepsis, transpl

121 Effective adaptive immune responses require a large repertoire of

122 nt changes to the microbiome, and innate and adaptive immune responses that are critical to the induc

123 uggests that progestins significantly affect adaptive immune responses to influenza A virus infection

124 n of alarmins in the induction of innate and adaptive immune responses, as well as their contribution

125 multifactorial components of the innate and adaptive immune responses, controls parasitemia, and blo

126 r, the existing models cannot support robust adaptive immune responses, especially the generation of

127 (DCs), which integrate vaccine signals into adaptive immune responses, might enable development of a

128 negatively affected by a range of innate and adaptive immune responses, resulting in alterations in t

129 apies include activation of either innate or adaptive immune responses.

130 ition receptors might also play key roles in adaptive immune responses.

131 ted because of the insufficient induction of adaptive immune responses.

132 information to generate tailored protective adaptive immune responses.

133 crobiota, leading to dysregulated innate and adaptive immune responses.

134 lso involved in the regulation of innate and adaptive immune responses.

135 nes associated with inflammatory, innate and adaptive immune responses.

136 vels, thereby presumably fostering efficient adaptive immune responses.

137 fects of the anti-CCR4 antibody required the adaptive immune system and CD4+ T cells.

138 n at steady state, while the presence of the adaptive immune system elevates their activation state.

139 Historically, only cells of the adaptive immune system have been considered capable of r

140 -Cas9 genome-editing system is a part of the adaptive immune system in archaea and bacteria to defend

141 ies examine the activation of the innate and adaptive immune system in obesity; inflammation within d

142 The type I-F CRISPR adaptive immune system in Pseudomonas aeruginosa (PA14)

143 Activation of cells in the adaptive immune system is a highly orchestrated process

144 lity Complex (MHC) is a key component of the adaptive immune system of all vertebrates and consists o

145 st-stroke autoimmune complications driven by adaptive immune system overactivation, and that CD163 is

146 The enteric microbiota and the innate and adaptive immune system represent prime candidates that i

147 form in-depth systems analysis of innate and adaptive immune system responses to implanted biomateria

148 The ability of the adaptive immune system to respond to arbitrary pathogens

149 ibodies are critical components of the human adaptive immune system, providing versatile scaffolds to

150 metabolites interacting with the innate and adaptive immune system, which would set the basis for pr

151 , delta-opioid receptors, and T cells of the adaptive immune system.

152 of the biological function of CRISPR-Cas as adaptive immune systems in bacteria.

153 CRISPR-Cas are prokaryotic adaptive immune systems that provide protection against

154 the effect of aging on cells of the (mostly adaptive) immune system, on soluble molecules that guide

155 Both innate and adaptive immunities are involved.

156 ecific CD4 TRM cells play a critical role in adaptive immunity against reinfection and memory induced

157 Given this role in adaptive immunity and its highly monomorphic nature in t

158 tion of lymphocytes by antigen is central to adaptive immunity and self-tolerance, yet how this is de

159 fundamental principles of innate control of adaptive immunity are well established, it is not fully

160 HIV-associated dysregulation of adaptive immunity by depletion of CD4 Th cells most like

161 CRISPR-Cas systems provide microbes with adaptive immunity by employing short DNA sequences, term

162 ombinase (RAG1/2) plays an essential role in adaptive immunity by mediating V(D)J recombination in de

163 he coordinated activation of both innate and adaptive immunity can effectively reduce the risk of tum

164 The role of adaptive immunity in early cancer development is controv

165 vely, these findings provide a mechanism for adaptive immunity involvement in the kidney defect in so

166 Adaptive immunity is driven by the expansion, somatic hy

167 Using our experimental model, impact of adaptive immunity on S. aureus colonisation could be ass

168 with immunogenic reprogramming of innate and adaptive immunity within the TME.

169 Adaptive immunity, addressed here, integrates the activi

170 duced neuroinvasiveness, induction of strong adaptive immunity, and protection of mice from wild-type

171 NA recombination, the hallmark of vertebrate adaptive immunity, has the potential to generate a vast

172 ction, suggesting that NK cells, but not HCV adaptive immunity, may contribute to HCV viral control f

173 is is known to produce antigenic peptides in adaptive immunity, our findings demonstrate its new role

174 of B cell activation, as it links innate and adaptive immunity, promoting potent B cell responses.

175 and how Nod1 and Nod2 proteins contribute to adaptive immunity, this study investigated their role in

176 ve a reduced innate immune response and lack adaptive immunity, would be susceptible to the infection

177 ng enzymes, and a wide variety of innate and adaptive immunity-related proteins.

178 tes and is essential for T cell function and adaptive immunity.

179 hich enables disease to progress unabated by adaptive immunity.

180 ietic cells initiate and maintain innate and adaptive immunity.

181 in Down syndrome, suggesting abnormality of adaptive immunity.

182 s neuronal circuits that regulate innate and adaptive immunity.

183 centre (GC) response is a pivotal process in adaptive immunity.

184 ts operating reflexively regulate innate and adaptive immunity.

185 te immune system, and how this may influence adaptive immunity.

186 pathogen-specific Vgamma4 cells function in adaptive immunological memory against B. pertussis.

187 ell death, and whether this process could be adaptive in vivo, are two major unanswered questions con

188 Following adaptive laboratory evolution (ALE), the knockouts incre

189 s for protein engineering, reconstruction of adaptive laboratory evolution experiments, and identific

190 ng slow but continuous reorganization of the adaptive landscape of mutualistic partners under changin

191 he evolutionary dynamics by transforming the adaptive landscape that relates genotype to fitness.

192 Computer adaptive learning method reinforced learning by embeddin

193 between adaptability and precision and thus adaptive learning.

194 we proposed an Image Downsampling Expedited Adaptive Least-squares (IDEAL) fitting algorithm that qu

195 believe that this example of engineering an adaptive Li/electrolyte interface brings about a new and

196 ng of the [YbO2] sub-units controlled by the adaptive Ln/Fe oxygen coordination and the Fe(2/3+) redo

197 dditionally, a substantial proportion of the adaptive lymphocytes that are found in the kidney displa

198 In adaptive lymphoid cells EZH2 prevented the premature exp

199 uitment dynamics of eels and suggest that an adaptive magnetic map, tuned to large-scale features of

200 abundance and productivity may be useful for adaptive management of marine resources, but their suita

201 nt to span across administrative boundaries, adaptive management, markets that incorporate natural ca

202 he harvested area being less available as an adaptive margin to hydrological stress.

203 Perennial plants have evolved an adaptive mechanism involving protection of meristems wit

204 This study reveals an adaptive mechanism that harnesses synergistic paracrine

205 Adaptive mechanisms employed in the control of sickness

206 everal endogenous vasoactive peptides act as adaptive mechanisms, and their augmentation could help t

207 s, and provide direct chemical evidence that adaptive melanism - a biological means used by extant se

208 ptive generalized memories without affecting adaptive memories.

209 that IAH develops through a special type of adaptive memory referred to as habituation.

210 Finally, we incorporate the data adaptive method in order to compare false positive rates

211 rates are controlled after applying the data adaptive method.

212 e et al. miss the crucial difference between adaptive models of storing energy and explanations for t

213 nential, supporting a current hypothesis for adaptive molecular evolution.

214 Adaptive mutations in pathogenesis-associated genes were

215 ptive antiviral therapy, suggesting that the adaptive NK cell response may be inversely related with

216 Moreover, our data suggest that adaptive NK cells are more long-lived than canonical, im

217 dings support the existence of a long-lived, adaptive NK-cell population maintained independently fro

218 ogether, our results indirectly support that adaptive NKG2C(+) NK cells are involved in the control o

219 te clinical and ancillary testing, including adaptive optics, outcomes in autoimmune retinopathy (AIR

220 remained quite similar whatever the methods, adaptive or 41% SUVmax, supporting its use as a strong p

221 Finally, we emphasize the need to use adaptive path-based approach instead of single point tar

222 A poorly understood adaptive pathway links cytoplasmic slicing of target RNA

223 Moreover, our results may suggest that adaptive pathways co-evolved with the expansion of IDDs

224 h genetic changes propel organisms toward an adaptive peak of chemical defense.

225 of a global motion discrimination task with adaptive performance staircasing revealed that noradrene

226 and early findings of the Care Ecosystem, an adaptive, personalized, and scalable dementia care progr

227 lysis from GATSBY, a randomised, open-label, adaptive, phase 2/3 study, done at 107 centres (28 count

228 Dormancy has been hypothesized to be an adaptive physiological mechanism that has been linked to

229 AESOP utilizes PDB2PQR and Adaptive Poisson-Boltzmann Solver to generate grid-based

230 The adaptive policy optimized for middle-income resource set

231 ps of various NK-cell subsets, including the adaptive population, by taking advantage of naturally oc

232 Thus, the adaptive potential of a gene under selection is a system

233 ransfemoral amputees could benefit from load-adaptive powered knee controllers, and controller adjust

234 is a serious human pathogen with remarkable adaptive powers.

235 regulatory RNA (sRNA) is critical for rapid adaptive processes.

236 Homeostatic activation of the UPR enforces adaptive programs that modulate and augment key aspects

237 olution of the supergene is dominated not by adaptive protein evolution or balancing selection, but b

238 Intriguingly, MAGE-F1 has undergone adaptive pseudogenization in select mammalian lineages.

239 n of negative affect is one key mechanism of adaptive psychotherapeutic change in PTSD.

240 e explain how these constraints give rise to adaptive quantal information sampling in time, which max

241 This finding may help explain why adaptive radiation is common on oceanic archipelagoes -

242 lends support to idea that there was a major adaptive radiation of mammals in the mid-Jurassic period

243 n object is, dorsal representations are more adaptive, reflecting what we do with the object.

244 r immune checkpoint blockade, arguing for an adaptive resistance mechanism.

245 enomic reprogramming underlie the innate and adaptive resistance of RISC cells, and both need to be t

246 endencies toward danger and reward, enabling adaptive responding under this basic selection pressure.

247 t EGFRvIII, EGFR inhibition triggers a rapid adaptive response driven by increased tumor necrosis fac

248 aturation of the fetal lung, which may be an adaptive response in preparation for the successful tran

249 , and RNAi approaches demonstrates that this adaptive response is critical for HRas-induced prolifera

250 hether the temporal structure of the initial adaptive response is, in fact, stereotyped and non-speci

251 ese effects appear to reflect a homeostatic, adaptive response of auditory nerve synapses to reduced

252 imaging and microfluidics to investigate the adaptive response of budding yeast to temporally control

253 nal activity of HIF-1alpha and strengthening adaptive response of cells to hypoxia.

254 ment-binding protein (ChREBP) coordinates an adaptive response to a high-fructose diet in mice and th

255 nfer aggressive molecular features, being an adaptive response to endogenous DNA damage and oncogene-

256 It is proposed that thalamic bursts are an adaptive response to pain that de-synchronizes cortical

257 n the Control group, which suggests a rapid, adaptive response toward threat.

258 Cardiac hypertrophy is an adaptive response triggered by pathological stimuli.

259 cal environment eventually leads to a mature adaptive response whereby feedforward changes in motor o

260 ith aquatic larvae, and thus they might lack adaptive responses against waterborne chytrids.

261 However, adaptive responses at the earliest stages of learning ha

262 d in lymph nodes (LNs), but how this affects adaptive responses has not been extensively studied.

263 -155 has recently been described to regulate adaptive responses in allergic inflammation.

264 etory neurons (MNCs), as well as homeostatic adaptive responses to a physiological challenge.

265 r of stress may be beneficial if it enhances adaptive responses to ecological stressors in the shared

266 settle this debate, we directly measured the adaptive responses to velocity-dependent and position-de

267 erved these differences between single-trial adaptive responses when vFF and pFF perturbations were r

268 rated to be important for the development of adaptive responses.

269 The emergence is effectuated through adaptive rewiring: progressive adaptation of structure t

270 s in neuronal cell bodies, hence may play an adaptive role to stresses that impair axonal transport.

271 ons in rodents because they are endowed with adaptive scalability and context dependency.

272 pears to play a versatile and active role in adaptive sensorimotor prioritization.SIGNIFICANCE STATEM

273 investigated whether minute ventilation (MV) adaptive servo-ventilation (ASV) improved cardiovascular

274 Mechanisms of Se hyperaccumulation and its adaptive significance appear to involve constitutive up-

275 s robust to changes in stimulus ensemble and adaptive state.

276 Here we present a novel adaptive statistical method to simultaneously address bo

277 demonstrates that Synechococcus has distinct adaptive strategies to deal with Cu toxicity at both the

278 ed reactive oxygen species (ROS) activate an adaptive stress response to promote longevity.

279 rodents to establish the motor cortex as an adaptive structure that supports motor learning.

280 s that innate lymphoid cells (ILCs) regulate adaptive T cell responses led us to examine the regulato

281 rated during cell motility are essential for adaptive T-cell immunity against infectious pathogens an

282 Adaptive therapy, using patient-specific tumor dynamics

283 ave a direct role in adipocyte metabolism or adaptive thermogenesis.

284 nses of ASP and SSP of A. edgeworthii may be adaptive to the range of low to high light environments

285 NA to generate a potent transcription factor adaptive toward ER stress.

286 pact of recent admixture on the diffusion of adaptive traits across human populations.

287 to the acquisition by domesticated beans of adaptive traits from wild relatives.

288 uence the response to selection, shaping the adaptive trajectories of natural populations in complex

289 combination with BRAF inhibition, halted the adaptive transition and led to prolonged growth inhibiti

290 nt randomized trials to develop personalized adaptive treatment strategies (ATSs)-longitudinal practi

291 behavior-specific cell populations, enabling adaptive tuning of emotional responding and behavioral f

292 H-sensitized acinar cells by suppressing the adaptive unfolded protein response signaling pathway.

293 The dynamics of this adaptive valuation are captured by divisive normalizatio

294 Criticality can be adaptive when the environment is changing, but entails r

295 cide of unrelated young may generally become adaptive when the risks and costs of misdirected care ar

296 ed p < 0.0008) and nontrained WM tests after adaptive WMT (FDR corrected, p </= 0.001), but not after

297 total of 74 of 76 (34 HIV, 42 SN) completed adaptive WMT and all 40 completed nonadaptive WMT (20 HI

298 SN) and were assessed after 1 month, and 55 adaptive WMT participants were also assessed after 6 mon

299 tes, and LMX1A-rs4657412 polymorphism on the adaptive WMT, in human immunodeficiency virus (HIV) part

300 We aimed to evaluate the effectiveness of an adaptive working memory (WM) training (WMT) program, the