ライフサイエンスコーパス: adaptive response

1 ng innate immune activation to afford better adaptive response.

2 f innate immunity and consequently shape the adaptive response.

3 disease, allowing the host time to mount an adaptive response.

4 ough the latter group exhibits a more robust adaptive response.

5 ng evidence that the inhibition of NMD is an adaptive response.

6 t, phosphorus deprivation induced a stepwise adaptive response.

7 ault GFRs and adjusted for the single kidney adaptive response.

8 le for circulating factors in the intestinal adaptive response.

9 ependent, programmed response is part of the adaptive response.

10 flammatory pathways, with down-regulation of adaptive responses.

11 revailing flooding conditions and subsequent adaptive responses.

12 ncertainty representations to engender fast, adaptive responses.

13 r role in orchestrating master regulators of adaptive responses.

14 e stress sensor that largely acts to promote adaptive responses.

15 rated to be important for the development of adaptive responses.

16 ate cells, and promoting Th1 polarization of adaptive responses.

17 rgannellar communication in shaping cellular adaptive responses.

18 e also improving OVA-specific humoral B cell adaptive responses.

19 eron response and control of both innate and adaptive responses.

20 nd nutrient availability and thereby trigger adaptive responses.

21 links energetic substrate flux with cellular adaptive responses.

22 mmune activation and subsequent induction of adaptive responses.

23 rates internal and external cues to initiate adaptive responses.

24 f contingency that may reflect strategically adaptive responses.

25 7 treatment, further bridging the innate and adaptive responses.

26 n many cases social perception should favour adaptive responses.

27 cal functions that influence both innate and adaptive responses.

28 neuronal disorders associated with impaired adaptive responses.

29 or overlapping functions of MEcPP and SA in adaptive responses.

30 dependent signaling cascades instrumental in adaptive responses.

31 Delayed adaptive responses, a hallmark of M. tuberculosis infect

32 like autoimmunity, represents a dysregulated adaptive response: a stress response that has gone awry.

33 ds to a unique antiviral IFN-I signature and adaptive response after virus infection that protects fr

34 ith aquatic larvae, and thus they might lack adaptive responses against waterborne chytrids.

35 lated macromolecular synthesis, the extended adaptive response also includes inhibited glycolysis, an

36 beta to Axl(-/-) mice restored the antiviral adaptive response and control of infection.

37 That this represented an adaptive response and not an adverse toxic effect was in

38 addressed phenotypic dynamics by considering adaptive response and persister formation separately.

39 ria, yet the carbohydrate starvation induced adaptive response and the roles of SR in this response i

40 ic and proteomic platform to understand this adaptive response and thereby design rational combinator

41 stimuli to roots in ways that evoke natural adaptive responses and in providing tools for studying t

42 transcription 3 (STAT3) signalling to favour adaptive responses and shift cell fate from apoptosis to

43 ne photoreceptors (S-cones) did not show the adaptive response, and we found they also lacked a promi

44 nsulin; however, the pathways governing this adaptive response are not entirely established.

45 eption of salient stimuli to execution of an adaptive response are poorly understood.

46 ry microvascular changes responsible for the adaptive response are unknown.

47 tent infection suggest that innate and rapid adaptive responses are critical to preventing active tub

48 cells and developing functional human T-cell adaptive responses are in critical demand to test human-

49 However, the mechanisms of these adaptive responses are incompletely understood, and it i

50 However, more rapid adaptive responses are possible if selectable or plastic

51 bacteria to couple environmental stimuli to adaptive responses, are absent in mammals, and are embed

52 anism where A20 is induced by stress-induced adaptive response as a result of modulation of sphingoli

53 th omics data sets and allow acclimation and adaptive response at the phenotype level (i.e. traits) t

54 However, adaptive responses at the earliest stages of learning ha

55 inished capacity for short-term (reversible) adaptive responses (both biochemical and signal transduc

56 not only induction of mycobacterial-specific adaptive responses but also signaling via MyD88 and Fas

57 These results support the induction of an adaptive response by BPA co-exposure that alters the mic

58 These data point towards an agonist-induced adaptive response by KOR, the dynamics of which have not

59 d, human mitoribosome biogenesis displays an adaptive response by switching to the incorporation of m

60 also contribute to the orchestration of the adaptive response by their ability to produce immunoregu

61 ially conserved strategy for interference in adaptive responses by attaching and effacing E. coli.

62 of the immune system function in innate and adaptive responses by directing activity of various effe

63 vitable catalyst of change and that promotes adaptive responses by ecosystems and residential communi

64 vealed that the mechanism for these critical adaptive responses by eIF2alpha-P involved induced expre

65 Protection against helminths consists of adaptive responses by TH2 cells and innate responses by

66 challenge is the loss of a metabolic enzyme, adaptive responses can also shed significant insight int

67 activities of premotor populations and their adaptive responses can be used, after brief training, to

68 Antagonizing these adaptive responses could improve drug effects, thereby t

69 importance by active management or species' adaptive responses, declines of some amphibians may be p

70 This adaptive response developed between 6 and 12 months of a

71 Dendritic cells (DC), which trigger the adaptive response, do not mature despite EBOV infection.

72 t EGFRvIII, EGFR inhibition triggers a rapid adaptive response driven by increased tumor necrosis fac

73 d innate immunity and its connections to the adaptive response during this infection.

74 lling networks displaying ultrasensitive and adaptive response dynamics.

75 apable of displaying both ultrasensitive and adaptive response dynamics.

76 As part of this adaptive response, eIF2alpha-P also induces a feedback m

77 and disease as well as probes of innate and adaptive responses employed by the host to deal with the

78 innate responses and/or rapid recruitment of adaptive responses, especially in the airway, should be

79 Before resistance emerges, adaptive responses establish a mutation-independent drug

80 in ATP level caused by HSF1 loss invoked an adaptive response featuring the inhibition of energetica

81 d as a critical step in the understanding of adaptive responses following infection or vaccination or

82 creased prosocial behavior is a contextually adaptive response for lower-SES individuals that serves

83 However, the single-trial adaptive responses for vFF and pFF perturbations were cl

84 cell death pathways with distinct innate and adaptive responses from classical apoptosis that can sha

85 d in lymph nodes (LNs), but how this affects adaptive responses has not been extensively studied.

86 Although host innate and adaptive responses have a role in viral clearance and pr

87 We examined the renal adaptive response in mice subjected to 7 days of a low s

88 of mitochondrial FAO also initiates a local, adaptive response in muscle that invokes mitochondrial b

89 aturation of the fetal lung, which may be an adaptive response in preparation for the successful tran

90 n and surfactant maturation, which may be an adaptive response in preparation for the successful tran

91 terization of the glucose starvation induced adaptive response in S. suis makes a great contribution

92 Here we show that stromal cues elicit an adaptive response in the cancer cell including the rapid

93 It is the first 'anti-arrhythmic' adaptive response in the setting of AF and appears to co

94 -155 has recently been described to regulate adaptive responses in allergic inflammation.

95 Pharmacologically induced glycosuria elicits adaptive responses in glucose homeostasis and hormone re

96 Our findings thus demonstrate that adaptive responses in glucose metabolism contribute to m

97 tin levels fall during starvation and elicit adaptive responses in many other physiologic systems, th

98 e the plant with the environment to generate adaptive responses in plants to improve growth.

99 the DeltawaaL mutant promoted Th1-associated adaptive responses in previous studies, we assessed NU14

100 Stressors trigger adaptive responses in the body that are essential for su

101 At the cellular level, such adaptive responses include the "strengthening" of existi

102 IRE1 activation orchestrates adaptive responses, including lipid anabolism, metabolic

103 he NF-kappaB transcription factor is a major adaptive response induced upon treatment with EGFR kinas

104 The adaptive response initiated by FVB/N mice was not involv

105 enic tumor models via a concerted innate and adaptive response involving neutrophils, NK cells, macro

106 esence of a PI3Kbeta inhibitor identified an adaptive response involving the IGF1R-PI3Kalpha axis.

107 , and RNAi approaches demonstrates that this adaptive response is critical for HRas-induced prolifera

108 es of deleterious mutations and the cellular adaptive response is imperative so that therapeutic targ

109 One example of such an adaptive response is the buildup of acquired neuroprotec

110 An unexpected benefit of this adaptive response is the complete resistance to diet-ind

111 duced stress it is important to know if this adaptive response is truly localised in the context of o

112 wever, the molecular basis for this enhanced adaptive response is unknown.

113 hether the temporal structure of the initial adaptive response is, in fact, stereotyped and non-speci

114 importance of cell type specificity in plant adaptive responses is widely accepted, only a limited nu

115 required for the activation of the antiviral adaptive response, it has a regulatory role in early cyt

116 To achieve an optimally tuned adaptive response, it is critical that the magnitude of

117 ereas closely related progenitors exhibit an adaptive response leading to their survival.

118 system is part of a previously unrecognized adaptive response linking ribosome homeostasis with basi

119 a-induced increases in hemoglobin levels, an adaptive response mainly regulated by HIF-2alpha.

120 ing Gln metabolism in combination with these adaptive responses may yield clinical benefits for patie

121 Mitochondrial biogenesis may be an adaptive response necessary for meeting the increased me

122 Adaptive responses observed in wild-type mice on the MCD

123 ese effects appear to reflect a homeostatic, adaptive response of auditory nerve synapses to reduced

124 imaging and microfluidics to investigate the adaptive response of budding yeast to temporally control

125 A combined adaptive response of carbon-catabolism and enzyme produc

126 nal activity of HIF-1alpha and strengthening adaptive response of cells to hypoxia.

127 ntly deleted, and copy number influences the adaptive response of NKG2C(+) NK cells.

128 imed to investigate the role of magnitude in adaptive response of osteoblasts exposed to compressive

129 rogen-suppressed gene upregulated during the adaptive response of prostate tumors to ATTs and a progn

130 ity in patients with PAH, with an inadequate adaptive response of the cholinergic system in the RV.

131 hat these changes may represent a short-term adaptive response of the heart in response to acute chan

132 r-1 receptor system as a major player in the adaptive response of the myocardium.

133 data indicate that hepatic XBP1 controls the adaptive response of the UPR and is critical to restorin

134 reveal genetic assimilation as a potentially adaptive response of Trichodesmium and importantly eluci

135 heparan sulfate proteoglycans (HSPG) in the adaptive response of tumor cells to hypoxia and acidosis

136 .5% cholic acid chow for 6 days, resulted in adaptive responses of altered expression of hepatic gene

137 Local mRNA translation mediates the adaptive responses of axons to extrinsic signals, but di

138 To understand the adaptive responses of group A Streptococcus (GAS) to zin

139 ved oxygen, salinity, and upwelling; and (4) adaptive responses of marine organisms to climate-driven

140 ver, enhanced SK activity contributes to the adaptive responses of MNCs to physiological challenge, s

141 the role of mitochondrial biogenesis in the adaptive responses of skeletal muscle to exercise is wel

142 uced obesity influence underlying innate and adaptive responses of the intestinal immune system.

143 The lack of inclusion of adaptive responses of vegetation communities to the envi

144 ABSTRACT: 'Adaptive' responses of the liver to chronic alcohol cons

145 firing rate triggered synaptic and intrinsic adaptive responses operating as global homeostatic mecha

146 hout impinging on UPR-dependent survival and adaptive responses or normal immune responses.

147 ization constitute physiologically relevant, adaptive responses, pointing to a pivotal role of the en

148 a are consistent with the delayed innate and adaptive responses previously observed in immunocompeten

149 nymous family member is an Escherichia coli "adaptive response" protein that protects the bacterial g

150 This may be an adaptive response providing protection against organ dam

151 ne expression, necessary for development and adaptive responses, relies not only on RNA transcription

152 Patients with symptoms presumably have an adaptive response resulting in lower blood levels of AOP

153 ion across single environments, the species' adaptive response should be constrained along few major

154 xt of projected warming up to 2100 indicates adaptive responses should focus on increasing wheat tole

155 vironment, notably by developing a metabolic adaptive response, some of these modifications may likel

156 ese dysregulated responses might impair more adaptive responses such as containment of distress, safe

157 proproliferative role for PKD1 in epidermal adaptive responses, suggesting a potential therapeutic t

158 perturbations in ER homeostasis activates an adaptive response termed the unfolded protein response (

159 inst liver steatosis via an oxidative stress adaptive response that activates the AMPK pathway.

160 tes and macrophages as part of an endogenous adaptive response that can be enhanced therapeutically t

161 process appears to represent a conserved and adaptive response that contributes to optimal survival d

162 and plays a key role triggering the delayed adaptive response that ensures an efficient defense agai

163 order, the cellular pathways involved in the adaptive response that is activated upon exposure to HPb

164 n synthase kinase-3 (GSK-3)beta represent an adaptive response that might limit the extent of adverse

165 endothelial cells of inflamed mucosa were an adaptive response that modulated the severity of tissue

166 -regulation in inflamed colonic mucosa is an adaptive response that modulates the severity of tissue

167 rt) functions as an 'alerting' mechanism, an adaptive response that positions stem cells to respond r

168 table client proteins, many of which mediate adaptive responses that allow organisms to adapt and thr

169 erate as an inhibitor of T lymphocyte immune adaptive responses that are not required until later in

170 and systemic DDR mechanisms that orchestrate adaptive responses that augment maintenance of the aging

171 vation of IL-1alpha and, thus, initiation of adaptive responses that cause graft rejection.

172 l consequences of this metabolic stress, the adaptive responses that cells utilize under this conditi

173 tic changes at OXTR may represent predictive adaptive responses that could impart readiness to respon

174 ygen deprivation induces a range of cellular adaptive responses that enable to drive cancer progressi

175 jury of the target organ, attempts to invoke adaptive responses that protect against acute kidney inj

176 its downstream effects function initially as adaptive responses that serve as compensatory mechanisms

177 This study provides a window into the adaptive responses that the host animal and its symbiont

178 Adaptive responses, though essential for survival, can b

179 e Unfolded Protein Response (UPR) to trigger adaptive responses through the effectors, PERK, IRE1 and

180 ment-binding protein (ChREBP) coordinates an adaptive response to a high-fructose diet in mice and th

181 ropsychiatric model of resilience, a crucial adaptive response to adversity.

182 Emulating this endogenous adaptive response to alpha-synuclein overexpression coul

183 Autophagy is a fundamental adaptive response to amino acid starvation orchestrated

184 es to massive introgression can permit rapid adaptive response to anthropogenic selection and (2) tha

185 There is an observed perturbation of the adaptive response to antigens from the microbiota in all

186 The transcription factor Nrf2 coordinates an adaptive response to chemical and oxidative stress chara

187 ion of FGF19 and other genes relevant to the adaptive response to cholestasis in tissues from non-cir

188 in the fossil record therefore indicates an adaptive response to complex ecological pressures.

189 g that temporal discounting is a functional, adaptive response to deprivation.

190 The molecular profiles that generate the adaptive response to different exercise modes have under

191 nfer aggressive molecular features, being an adaptive response to endogenous DNA damage and oncogene-

192 key mediator of the UPR, in controlling the adaptive response to ER stress in the liver.

193 e research exploring the role of IL-6 in the adaptive response to exercise.-Hennigar, S.

194 ates the initiation of rib broadening was an adaptive response to fossoriality.

195 SIRT6 is highly expressed in MM cells, as an adaptive response to genomic stability, and that high SI

196 Cardiac hypertrophy is often initiated as an adaptive response to haemodynamic stress or myocardial i

197 ciated with a low socioeconomic status is an adaptive response to having relatively little control ov

198 on of mNT is a key component of the cellular adaptive response to help stress-sensitive Fe-S proteins

199 Myocardial hypertrophy is an adaptive response to hemodynamic demands.

200 r, the cancer cells often quickly develop an adaptive response to HER2 kinase inhibitors.

201 genes during clinical UTI in patients as an adaptive response to host-derived Cu.

202 or (HIF), a master regulator of the cellular adaptive response to hypoxia.

203 ble factors that play important roles in the adaptive response to hypoxia.

204 neuron dendritic remodeling in ataxia is an adaptive response to increases in intrinsic membrane exc

205 lcohol-induced FGF21 expression is a hepatic adaptive response to lipid dysregulation.

206 sis that reduced root secondary growth is an adaptive response to low phosphorus availability and mer

207 that HSPGs may have an important role in the adaptive response to major stress factors of the tumor m

208 ed protein kinase in vitro and in vivo As an adaptive response to manassantin-induced bioenergetic de

209 sting that their accumulation represented an adaptive response to metabolic stress.

210 facet to the regulatory basis that underpins adaptive response to N stress.

211 Sleep loss is an adaptive response to nutrient deprivation that alters be

212 tion of ribosome biogenesis may be a general adaptive response to overcome functional insufficiencies

213 changes in ribosomes may be involved in the adaptive response to oxidative stress.

214 It is proposed that thalamic bursts are an adaptive response to pain that de-synchronizes cortical

215 toring for previously defined markers of the adaptive response to purine starvation, we determined th

216 a novel and distinct cellular and molecular adaptive response to rapid cardiac activation.

217 that acts as signalling molecule regulating adaptive response to salt stress.

218 ventricular hypertrophy (LVH) develops as an adaptive response to sarcomere dysfunction.

219 As part of the immune system's adaptive response to specific infections or neoplasms, a

220 eveal an unrecognized aspect of the cellular adaptive response to starvation, mediated by LDs.

221 First described in yeast as an adaptive response to starvation, this pathway is also pr

222 se of ER stress induced by tunicamycin as an adaptive response to stimulate mitochondrial bioenergeti

223 ning bHLH transcription factor that mediates adaptive response to stress via its downstream transcrip

224 ess, suggesting that LSD1 is involved in the adaptive response to stress.

225 ces cell survival by promoting the immediate adaptive response to stress.

226 e stress response is an innate, stereotypic, adaptive response to stressors that has evolved in the s

227 acy of SSRIs likely depends upon the brain's adaptive response to sustained increases in serotonin le

228 urrent upregulation of autophagic flux as an adaptive response to TAE-like ischemia was found by the

229 role of mitochondrial activity changes in an adaptive response to the development of PE.

230 er this is part of the disease process or an adaptive response to the pathology.

231 As an adaptive response to this exaggerated immune state, affe

232 Fear, which represents a highly conserved adaptive response to threatening environmental stimuli,

233 kinetics, and consistency of the innate and adaptive response to vaccination with the seasonal influ

234 In this study, we examined the adaptive response to VEGF-A inhibition by a loss-of-func

235 The latter represents an adaptive response to viability selection favouring juven

236 cellular dormant state, thereby providing an adaptive response to what would otherwise be a deleterio

237 elucidate the signaling networks involved on adaptive responses to (CrVI) toxicity in plants.

238 controllers of neutrophil-driven innate and adaptive responses to a broad range of pathogens.

239 house gases-and from the demand side-through adaptive responses to a changing environment.

240 etory neurons (MNCs), as well as homeostatic adaptive responses to a physiological challenge.

241 previous work, we found these earliest stage adaptive responses to be more similar than the perturbat

242 Many bacterial adaptive responses to changes in growth conditions due t

243 Plant adaptive responses to changing environments involve comp

244 potential for phenotypic plasticity to allow adaptive responses to climate change, few experiments ha

245 ort Pepper and Nettle's (P&N's) hypothesised adaptive responses to deprivation.

246 that will build our understanding of organic adaptive responses to desertification.

247 r of stress may be beneficial if it enhances adaptive responses to ecological stressors in the shared

248 nases and response regulators, which mediate adaptive responses to environmental cues.

249 ern our daily lives, providing efficient and adaptive responses to environmental demands.

250 ant cell wall-loosening proteins involved in adaptive responses to environmental stimuli and various

251 lesterol homeostasis and a core component of adaptive responses to excess cellular cholesterol.

252 an independent influence on redox-sensitive adaptive responses to exercise and exercise recovery.

253 ly, represents a key molecule that regulates adaptive responses to foreign Ags.

254 d miR-429 regulates the switch between HIF-1 adaptive responses to HIF-3 survival responses by rapidl

255 tion factors (HIFs) regulate a wide array of adaptive responses to hypoxia and are often activated in

256 its transcriptional activity and leading to adaptive responses to hypoxia.

257 nnate responses while decreasing Ag-specific adaptive responses to infectious Ags.

258 IF1) is a transcription factor that mediates adaptive responses to ischemia.

259 Homeostatic systems mount adaptive responses to meet the energy demands of the cel

260 t vascular permeability in shaping beta-cell adaptive responses to metabolic demand by modulating the

261 Moths and songbirds show contrasting but adaptive responses to migrating through a moving flow, w

262 crucial for controlling the large palette of adaptive responses to NO3(-) mediated by NRT1.1 as they

263 esticide exposure have the ability to induce adaptive responses to novel agrochemicals?

264 cribe specific gene sets, activate bacterial adaptive responses to noxious environments.

265 but not sustainable integration of beta cell-adaptive responses to nutrient overabundance, obesity de

266 However, its long-term adaptive responses to ongoing anthropogenic CO2 increase

267 Meanwhile, human cells launch adaptive responses to overcome SiO2 NP toxicity.

268 fatty acid utilization, were consistent with adaptive responses to perturbations of O2/CO2 balance in

269 role in fetal growth and development through adaptive responses to perturbations of the maternal envi

270 These findings demonstrate that the initial adaptive responses to physical perturbations are not ste

271 However, we argue that adaptive responses to stress shift with age.

272 AMPs), as they die in the context of failing adaptive responses to stress.

273 c acid and have been implicated in mediating adaptive responses to stress.

274 ntal cortex (mPFC) is known to control these adaptive responses to stress.

275 Adaptive responses to stressful stimuli involving behavi

276 r Zn(2+) that are associated with regulating adaptive responses to subsequent lethal injury, includin

277 ing agents that concurrently target distinct adaptive responses to tamoxifen-mediated metabolic repro

278 Compensatory/adaptive responses to targeted inhibitors are frequently

279 Remarkably, loci controlling adaptive responses to the environment are the most frequ

280 y use receiver (REC) domains, which regulate adaptive responses to the environment as a function of t

281 Thus, Metrnl links host-adaptive responses to the regulation of energy homeostas

282 Fear promotes adaptive responses to threats.

283 d nutrient absorption, and may impair normal adaptive responses to training.

284 ems approaches to investigate the innate and adaptive responses to trivalent inactivated influenza va

285 settle this debate, we directly measured the adaptive responses to velocity-dependent and position-de

286 ther, we demonstrate that AdcR regulates GAS adaptive responses to zinc limitation and identify molec

287 n the Control group, which suggests a rapid, adaptive response toward threat.

288 Cardiac hypertrophy is an adaptive response triggered by pathological stimuli.

289 pha) is a transcription factor that triggers adaptive responses upon low oxygen conditions and plays

290 ntextualize the insult and inform a tailored adaptive response via T and B lymphocytes.

291 In the absence of adaptive response, we show that these mortality costs wo

292 Both the humoral and cellular Ag-specific adaptive responses were significantly reduced in Aim2-de

293 at difference between SC-19 and DeltarelA on adaptive responses when suffering glucose starvation, an

294 erved these differences between single-trial adaptive responses when vFF and pFF perturbations were r

295 cal environment eventually leads to a mature adaptive response whereby feedforward changes in motor o

296 wo additional days of training amplified the adaptive response, which appears to be mediated by PGC-1

297 ubthreshold levels required for a particular adaptive response while preventing entry into apoptosis.

298 e motor adaptation and the evolution of this adaptive response with continued training.

299 nutrient limitation, etc., not only trigger adaptive responses within bacteria to these specific str

300 Contributing factors that elicit important adaptive responses within the mucosa include the transcr