ライフサイエンスコーパス: addictive drug

1 in regulating the behavioral responses to an addictive drug.

2 the reinforcing actions of cocaine and other addictive drugs.

3 receptors in the effects of psychoactive and addictive drugs.

4 at mediate vision, memory, and the action of addictive drugs.

5 m was stimulated by food, sexual arousal, or addictive drugs.

6 liking of various rewards including food and addictive drugs.

7 tural rewards converges with that engaged by addictive drugs.

8 nt role in homeostatic adaptations caused by addictive drugs.

9 r system, modulates the rewarding effects of addictive drugs.

10 mission and a target for antidepressants and addictive drugs.

11 ological reward processes may be affected by addictive drugs.

12 an identifying functional characteristic of addictive drugs.

13 ehaviors involved in responses to stress and addictive drugs.

14 ental conditioned stimuli and the effects of addictive drugs.

15 behavioral markers of the propensity to take addictive drugs.

16 o the rewarding effects of several different addictive drugs.

17 ave been implicated in enhanced responses to addictive drugs.

18 tical site of synaptic plasticity induced by addictive drugs.

19 entral tegmental area in response to several addictive drugs.

20 accompany some of the behavioural effects of addictive drugs.

21 ilar methods to examine the effects of other addictive drugs.

22 ventral tegmental area (VTA) in response to addictive drugs.

23 egion important for the rewarding effects of addictive drugs.

24 vironment or by the inappropriate stimuli of addictive drugs.

25 vational effects of both natural rewards and addictive drugs.

26 er' and become possible treatments for other addictive drugs.

27 Addictive drugs affect acute responses and plasticity in

28 By increasing dopamine in the striatum, addictive drugs alter the balance of dopamine and glutam

29 internally acknowledged that nicotine is an addictive drug and cigarettes are the ultimate nicotine

30 l studies indicate that experimentation with addictive drugs and onset of addictive disorders is prim

31 ystem can modulate the reinforcing effect of addictive drugs and the anxiolytic effect of nicotine.

32 Cocaine is a highly addictive drug, and despite intensive efforts, effective

33 ral tegmental area (VTA) are a key target of addictive drugs, and neuroplasticity in this region may

34 s compulsive motivation or "wanting" to take addictive drugs; and (d) the idea that dysfunction of fr

35 The fundamental principle that unites addictive drugs appears to be that each enhances synapti

36 Alterations in behavior after exposure to addictive drugs are a striking example of chemical alter

37 duced in the central nervous system (CNS) by addictive drugs are of interest because of their relatio

38 The response to novelty and sensitivity to addictive drugs are positively correlated with the hormo

39 esolimbic dopamine-a defining feature of all addictive drugs-as a neural substrate for these drug-ada

40 Environmental stimuli repeatedly linked to addictive drugs become learned associations, and those s

41 vern activity-dependent synaptic plasticity, addictive drugs can derail the experience-driven neural

42 Exposure to addictive drugs can result in maladaptive alterations in

43 Addictive drugs cause persistent restructuring of severa

44 Persistent relapse to addictive drugs constitutes the most challenging problem

45 Not everyone who tries addictive drugs develops a substance use disorder.

46 , and its oligomerization may be relevant to addictive drug effects.

47 Chronic exposure to addictive drugs enhances cAMP response element binding p

48 s motor effects produced by marijuana and by addictive drugs enhancing dopamine levels in the Acb.

49 ug seeking in addicts and animals exposed to addictive drugs, even after abstinence or extinction.

50 a marker for neuroadaptive changes following addictive drug exposure.

51 n for and the reinforcement by both food and addictive drugs extends the argument for a common mechan

52 All addictive drugs facilitate dopamine transmission, and de

53 Addictive drugs have been hypothesized to access the sam

54 How do addictive drugs hijack the brain's reward system?

55 ely used to study motivational properties of addictive drugs in animals, but has rarely been used in

56 tine, one of the most widely used and highly addictive drugs in human use.

57 These cues are also processed like addictive drugs in that they activate mesolimbic reward

58 l rewards, with brain stimulation reward and addictive drugs included in the latter category.

59 Nicotine, like other addictive drugs including psychomotor stimulants, promot

60 Addictive drugs induce a dopamine signal that contribute

61 Addictive drugs induce a truncated form of fosB in the s

62 oadaptations induced by repeated exposure to addictive drugs is a persistent sensitized behavioral re

63 ation and consumption of HP foods as well as addictive drugs is discussed.

64 red the observation that a common feature of addictive drugs is to activate, by a double tyrosine/thr

65 It has been recently discussed that addictive drugs may hijack the learning-and-memory machi

66 Shared adaptations between addictive drugs may mediate core processes of addiction.

67 a (VTA) dopamine (DA) neurons in response to addictive drugs may underlie the transition from casual

68 ysiologically relevant concentrations of the addictive drug nicotine directly cause in vivo hippocamp

69 t of tobacco that drives use, and like other addictive drugs, nicotine reinforces self-administration

70 Methamphetamine is a popular and highly addictive drug of abuse that has raised concerns because

71 Methamphetamine is a highly addictive drug of abuse that is neurotoxic to dopamine t

72 t effective analgesics known but also highly addictive drugs of abuse.

73 SIGNIFICANCE STATEMENT: It is believed that addictive drugs often render an addict's brain reward sy

74 Repeated exposure to addictive drugs or alcohol triggers glutamatergic and ga

75 aal et al. find that exposure to any of five addictive drugs or exposure to a brief stressor produces

76 ressive predominance of rewarding effects of addictive drugs over their aversive properties likely co

77 l area (VTA) are modified during exposure to addictive drugs, producing sensitization, a progressive

78 Questions about the molecular actions of addictive drugs, prominently including the actions of al

79 ences and prolonged exposure of the brain to addictive drugs promote its development.

80 Addictive drug reinforcement and stress signaling involv

81 nistic kinship revealed between learning and addictive drug response behaviors in flies.

82 ine reward circuits known to be activated by addictive drugs (right posterior amygdala, posterior hip

83 Stress facilitates reinstatement of addictive drug seeking in animals and promotes relapse i

84 te into psychotic symptoms and contribute to addictive-drug-seeking behavior, anxiety and phobia.

85 and that it produces the hallmark effects of addictive drugs: sensitization, tolerance, physical depe

86 Addictive drugs share the ability to increase dopamine (

87 Addictive drugs steepen neuronal temporal reward discoun

88 Addictive drugs subvert normal synaptic plasticity mecha

89 inforcing biologically rewarding events, but addictive drugs such as cocaine can inappropriately exer

90 Addictive drugs such as cocaine induce synaptic plastici

91 antagonist of sensitized behavior induced by addictive drugs such as cocaine.

92 Our results suggest that addictive drugs such as ethanol alter NMDAR trafficking

93 as adaptations to chronic administration of addictive drugs such as psychostimulants and therapeutic

94 Exposure to addictive drugs such as psychostimulants produces persis

95 yle but also the immunomodulatory effects of addictive drugs, such as cocaine, may account for their

96 Cocaine is a highly addictive drug that binds to the dopamine transporter (D

97 Cocaine is a highly addictive drug that exerts its effects by increasing the

98 Morphine is a widely abused, addictive drug that modulates immune function.

99 Alcohol is an addictive drug that targets a variety of ion channels an

100 Although cocaine is known to be a highly addictive drug, there appears to be a select subset of i

101 tamate interaction in MSN that is usurped by addictive drugs to elicit persistent behavioural alterat

102 lecular changes induced by administration of addictive drugs to rodents.

103 Addictive drug use causes long-lasting changes in synapt

104 Many studies support a perspective that addictive drugs usurp brain circuits used by natural rew

105 Addictive drugs usurp neural plasticity mechanisms that

106 Methamphetamine is a popular addictive drug whose use is associated with multiple neu

107 Amphetamine, a highly addictive drug with therapeutic efficacy, exerts paradox

108 Nicotine is a widely used addictive drug, with an estimated 73 million Americans 1