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1 nificance (P = 1.5 x 10(-13) for rs12777823, additive model).
2 0.003 and p = 0.04, respectively, using the additive model).
3 ff above 60% coverage (p < 0.01; generalized additive models).
4 34) after adjustment for covariates under an additive model.
5 trends, and day of week using a generalized additive model.
6 risk for a variant SNP allele based on a log-additive model.
7 d percent fat mass was investigated under an additive model.
8 ingle-nucleotide polymorphism (SNP) using an additive model.
9 interval 1.10 to 1.56, P=0.002), assuming an additive model.
10 t PD (age > 59 years) were a recessive or an additive model.
11 e, generalized linear model, and generalized additive model.
12 variation for foliage and tuber blight on an additive model.
13 ts a significantly higher V (G) than does an additive model.
14 and 6 (MLS = 0.61 at 112.5 cM), all under an additive model.
15 locus and multiplicative models than for the additive model.
16 .6 +/- 0.4 kJ/mol) when considering a simple additive model.
17 tion in soybean and function in line with an additive model.
18 t climates were examined using a generalized additive model.
19 ned using penalized splines within a general additive model.
20 assessed using log-linear analyses under an additive model.
21 an allelic model, with similar results in an additive model.
22 inations was analyzed by using a generalized additive model.
23 between each SNP and each phenotype under an additive model.
24 4.0%; celiac disease, 4.1%) beyond a simple additive model.
25 AAs; this relationship appears to follow an additive model.
26 ubstantially better goodness of fit than the additive model.
27 ion single nucleotide polymorphisms using an additive model.
28 cancer risk allele for each SNP under a log-additive model.
29 deled baseline mortality using a generalized additive model.
30 ect cannot be approximated adequately by the additive model.
31 in ADCYAP1R1 (rs2267735) and asthma under an additive model.
32 ing stepwise model selection and generalized additive models.
33 , and half require more than five loci under additive models.
34 s, corresponding to dominant, recessive, and additive models.
35 ariation between traits that are not seen in additive models.
36 using change-score analysis and generalized additive models.
37 ctors than observations for both, linear and additive models.
38 r combined exposures under multiplicative or additive models.
39 covariate model with the aid of generalized additive modeling.
40 3.1 ms higher versus CC; 1-sided P=0.04) or additive model (0.06 SD [SE, 0.03] or 1.6 ms higher per
41 wide significance level [odds ratio (OR) for additive model = 1.61, 95%CI, 1.36-1.91, P = 3.2 x 10(-8
42 h overall HCC (odds ratio [OR] per G allele, additive model=1.77; 95% confidence interval [CI]: 1.42-
45 ducted separately in each sample assuming an additive model adjusted for age, sex and relatedness of
47 s was performed on whites for each SNP in an additive model adjusting for baseline BP, age, sex, and
48 a combined meta-analysis under recessive and additive models after adjusting for age, sex, body mass
49 alence) using this marker were 1.37 under an additive model and 1.36 under a multiplicative model.
53 The results were analyzed using generalized additive models and logistic regression, adjusting for r
55 homozygotes, assuming a multiplicative (log-additive) model and attributable fraction of 25% (95% CI
56 ded in an association analysis at 7 951 614 (additive model) and 4 669 537 (genotypic model) loci.
58 Partial Spearman's correlation, generalized additive models, and receiver operating characteristic (
59 hat of the two homozygotes); (2) 6 two-locus additive models; and (3) 16 two-locus heterogeneity mode
60 Risk prediction evaluation identified the additive model as best for describing the effect of APOE
64 ein can identify cases where an independent, additive model cannot be applied and so require addition
65 pared association tests based on a biallelic additive model constraining the effect of a single-nucle
67 h systolic and diastolic BP when a two-locus additive model developed for ACE concentration was used.
70 biomass burning, as detected by generalized additive models fitted to seven pollen and charcoal reco
71 ooled (P = 0.0010-0.00099) samples under the additive model, following correction for multiple testin
73 ve, which verifies the practice of using the additive model for analyzing SNP effects on metabolites.
74 ficients of the log-length correction in the additive model for arbitrary sequences and lengths and (
81 demonstrate how one can use the generalized additive models for location, scale and shape (GAMLSS) d
83 mograms were estimated by use of generalized additive models for location, shape, and scale with Box-
84 s were detected following reanalysis with an additive model (for example, for birth weight, beta = 20
85 ear models (for climate PC1) and generalized additive models (for biology PC1-2) invoking only the cl
87 obal climate model, and create a generalized additive model (GAM) to examine how future changes in te
89 ic (ROC) curves and multivariate generalized additive model (GAM) were applied to predict outcomes.
94 linear regression and nonlinear generalized additive models (GAMs) to estimate on-road concentration
97 y the same role) the predictions differ: the additive model has the same predictions as in the random
98 MELD >/=28 was higher than predicted by the additive model (HR=2.38, 95% CI 1.73-3.27, P<0.001) resu
99 anges in ACTN3 expression consistent with an additive model in the human genotype-tissue expression c
103 in cation/pi interactions is captured by an additive model in which the substituent is isolated from
104 plotype GC1s) was overtransmitted (P = 0.02, additive model) in the entire Boston cohort, in Whites (
106 was assessed by linear regression, using an additive model, in which absolute change in the Disease
108 uman skeletal muscle, but we suggest that an additive model is the most appropriate for use in testin
110 lues are factorized as a product between the additive model matrix and the h - 1 additive effects, an
111 e.g. maximum likelihood methods, generalized additive models, nonparametric kernel density estimators
112 CI], 1.82 to 3.26; P=1.42x10(-9); and in the additive model: odds ratio, 2.19; 95% CI, 1.66 to 2.90;
118 curve during an oral glucose tolerance test (additive model, P = 0.022; dominant model, P = 0.010).
119 R8 rs3764880-G (recessive model: p = 0.0173; additive model: p = 0.0161) were associated with pericar
120 cted mortality under medical treatment, with additive model predictive value (all, p </= 0.04) and a
130 ted SAR cases was analysed using generalized additive models, taking into account confounding factors
135 ndard deviations were detected; but under an additive model, these did not fully account for the obse
136 ical content on temperature is improved over additive models, though further sampling is required to
138 ate holistic system indicator variables, non-additive modelling to estimate alternate attractors, and
139 rmed a retrospective study using generalized additive models to analyze three major livestock populat
142 x proportional hazard models and generalized additive models to examine multivariable-adjusted associ
144 of field observations in the North Sea with additive models to infer spatiotemporal trends of chloro
145 d gene coexpression networks and generalized additive models to predict effects on reproduction in th
147 lies on the use of Time-Varying Group Sparse Additive Models (TV-GroupSpAM) for high-dimensional, fun
150 ation studies on AWT were performed under an additive model using linear regression (adjusted for pac
151 d glaucoma was obtained with the generalized additive model using only three parameters (AROC = 0.854
152 est evidence of an FcgammaR-SLE association (additive model: V/V 176 versus V/F 176 OR 1.51, V/V 176
153 T. aestivum gene expression was compared to additive model values (mid-parent) calculated from paren
154 justed hazard ratio for each L allele in the additive model was 1.91 (1.20 to 3.06; P=0.01) for the r
155 ariance analysis indicated that a completely additive model was adequate to explain the variances obs
157 Using the same covariates in a generalized additive model, we examined the shape of the relationshi
158 s of 272 UM cases and 1782 controls using an additive model, we identified five variants significantl
160 ographic and Health Surveys with generalized additive models, we quantify spatial patterns of measles
161 nfidence intervals) for each L allele in the additive model were 1.99 (1.27 to 3.14; P=0.003) for the
166 tivariate linear, piecewise, and generalized additive models were used to examine dose-response relat
170 nal study of 357 Yup'ik Eskimos, generalized additive models were used to plot covariate-adjusted ass
175 08 on 20p (location, chi = 19.5 cM) under an additive model, whereas the weighted MLS was 2.06 on 20q
177 polymorphisms (SNPs) and expression under an additive model, which ignores interaction and haplotypic
179 Cox proportional hazards regression under an additive model with adjustment for age at onset, sex, an
182 APOL1 risk alleles were associated under an additive model with systolic blood pressure (SBP) and ag
183 tistic is increased by >20%, on average, for additive models with modest genotype relative risks.
184 present study, the authors used generalized additive models with nonparametric smoothing splines to
185 ted to trait and state anxiety using general additive models with penalized splines, while controllin
186 Logistic regression models and generalized additive models with thin-plate splines were fit to the
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