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1 nificance (P = 1.5 x 10(-13) for rs12777823, additive model).
2  0.003 and p = 0.04, respectively, using the additive model).
3 ff above 60% coverage (p < 0.01; generalized additive models).
4 34) after adjustment for covariates under an additive model.
5  trends, and day of week using a generalized additive model.
6 risk for a variant SNP allele based on a log-additive model.
7 d percent fat mass was investigated under an additive model.
8 ingle-nucleotide polymorphism (SNP) using an additive model.
9 interval 1.10 to 1.56, P=0.002), assuming an additive model.
10 t PD (age > 59 years) were a recessive or an additive model.
11 e, generalized linear model, and generalized additive model.
12 variation for foliage and tuber blight on an additive model.
13 ts a significantly higher V (G) than does an additive model.
14 and 6 (MLS = 0.61 at 112.5 cM), all under an additive model.
15 locus and multiplicative models than for the additive model.
16 .6 +/- 0.4 kJ/mol) when considering a simple additive model.
17 tion in soybean and function in line with an additive model.
18 t climates were examined using a generalized additive model.
19 ned using penalized splines within a general additive model.
20  assessed using log-linear analyses under an additive model.
21 an allelic model, with similar results in an additive model.
22 inations was analyzed by using a generalized additive model.
23 between each SNP and each phenotype under an additive model.
24  4.0%; celiac disease, 4.1%) beyond a simple additive model.
25  AAs; this relationship appears to follow an additive model.
26 ubstantially better goodness of fit than the additive model.
27 ion single nucleotide polymorphisms using an additive model.
28  cancer risk allele for each SNP under a log-additive model.
29 deled baseline mortality using a generalized additive model.
30 ect cannot be approximated adequately by the additive model.
31 in ADCYAP1R1 (rs2267735) and asthma under an additive model.
32 ing stepwise model selection and generalized additive models.
33 , and half require more than five loci under additive models.
34 s, corresponding to dominant, recessive, and additive models.
35 ariation between traits that are not seen in additive models.
36  using change-score analysis and generalized additive models.
37 ctors than observations for both, linear and additive models.
38 r combined exposures under multiplicative or additive models.
39  covariate model with the aid of generalized additive modeling.
40  3.1 ms higher versus CC; 1-sided P=0.04) or additive model (0.06 SD [SE, 0.03] or 1.6 ms higher per
41 wide significance level [odds ratio (OR) for additive model = 1.61, 95%CI, 1.36-1.91, P = 3.2 x 10(-8
42 h overall HCC (odds ratio [OR] per G allele, additive model=1.77; 95% confidence interval [CI]: 1.42-
43                                  Generalized additive models, a type of semiparametric regression mod
44                               Thus, a simple additive model accurately predicts flowering time for ma
45 ducted separately in each sample assuming an additive model adjusted for age, sex and relatedness of
46                               In generalized additive models adjusted for patient, procedure, and ant
47 s was performed on whites for each SNP in an additive model adjusting for baseline BP, age, sex, and
48 a combined meta-analysis under recessive and additive models after adjusting for age, sex, body mass
49 alence) using this marker were 1.37 under an additive model and 1.36 under a multiplicative model.
50 different from those predicted from a purely additive model and could even aid adaptation.
51                              The generalized additive model and logistic regression were used to dete
52  resistance were evaluated using generalized additive models and Fisher exact tests.
53  The results were analyzed using generalized additive models and logistic regression, adjusting for r
54                                  Generalized additive models and segmented regression analysis were u
55  homozygotes, assuming a multiplicative (log-additive) model and attributable fraction of 25% (95% CI
56 ded in an association analysis at 7 951 614 (additive model) and 4 669 537 (genotypic model) loci.
57            Descriptive analysis, generalized additive models, and alternating logistic regression mod
58  Partial Spearman's correlation, generalized additive models, and receiver operating characteristic (
59 hat of the two homozygotes); (2) 6 two-locus additive models; and (3) 16 two-locus heterogeneity mode
60    Risk prediction evaluation identified the additive model as best for describing the effect of APOE
61 arly focusing on the limitations of existing additive models based on small molecule data.
62                               Derivations of additive models by least-squares and ridge-regression me
63                                   Therefore, additive models can be very useful for the discovery and
64 ein can identify cases where an independent, additive model cannot be applied and so require addition
65 pared association tests based on a biallelic additive model constraining the effect of a single-nucle
66                                  Generalized additive models demonstrated an association between the
67 h systolic and diastolic BP when a two-locus additive model developed for ACE concentration was used.
68               Our main aim is to compare the additive model, due to Mesterton-Gibbons, and the multip
69                        Nonlinear generalized additive models examined the association between timing
70  biomass burning, as detected by generalized additive models fitted to seven pollen and charcoal reco
71 ooled (P = 0.0010-0.00099) samples under the additive model, following correction for multiple testin
72 We used 2-way mixed linear regression and an additive model for all primary analyses.
73 ve, which verifies the practice of using the additive model for analyzing SNP effects on metabolites.
74 ficients of the log-length correction in the additive model for arbitrary sequences and lengths and (
75                Analysis of these two with an additive model for beta(J)(=1) and beta(J)(=3) reveals a
76              Finally, we demonstrate that an additive model for these APOE variants is superior to ot
77                           We fit generalized additive models for associations between pollutant expos
78                   VarWalker fits generalized additive models for each sample based on sample-specific
79 tion accuracy, significantly higher than the additive models for either HILIC or RPLC.
80 ls from 7 cohorts, which were analyzed using additive models for epsilon2 and epsilon4.
81  demonstrate how one can use the generalized additive models for location, scale and shape (GAMLSS) d
82                                  Generalized additive models for location, scale, and shape were used
83 mograms were estimated by use of generalized additive models for location, shape, and scale with Box-
84 s were detected following reanalysis with an additive model (for example, for birth weight, beta = 20
85 ear models (for climate PC1) and generalized additive models (for biology PC1-2) invoking only the cl
86             Two statistical models,a general additive model (GAM) and GAMBOOST model with boosted reg
87 obal climate model, and create a generalized additive model (GAM) to examine how future changes in te
88                        We used a generalized additive model (GAM) to identify significant change poin
89 ic (ROC) curves and multivariate generalized additive model (GAM) were applied to predict outcomes.
90                                A generalized additive modelling (GAM) approach is used to describe th
91                   We also fitted generalized additive models (GAM) and performed two-objective optimi
92                  The widely used generalized additive models (GAM) method is a flexible and effective
93                         Based on Generalized additive models (GAM), the proportional influence of reg
94  linear regression and nonlinear generalized additive models (GAMs) to estimate on-road concentration
95                       Non-linear generalized additive models (GAMs) were used to evaluate the influen
96 t 333 sampling sites by means of generalized additive models (GAMs).
97 y the same role) the predictions differ: the additive model has the same predictions as in the random
98  MELD >/=28 was higher than predicted by the additive model (HR=2.38, 95% CI 1.73-3.27, P<0.001) resu
99 anges in ACTN3 expression consistent with an additive model in the human genotype-tissue expression c
100  (95% CI, 0.90 to 1.37; P=0.35), assuming an additive model in the matched analysis.
101                          The data support an additive model in which individuals heterozygous for the
102                             In a generalized additive model in which the authors accounted for long-t
103  in cation/pi interactions is captured by an additive model in which the substituent is isolated from
104 plotype GC1s) was overtransmitted (P = 0.02, additive model) in the entire Boston cohort, in Whites (
105                                           An additive model, in which a chemical change in the struct
106  was assessed by linear regression, using an additive model, in which absolute change in the Disease
107                                           An additive model (incorporating the contributions of all 2
108 uman skeletal muscle, but we suggest that an additive model is the most appropriate for use in testin
109 D = 1.74; P=.024), compared with a two-locus additive model (LOD = 0.90).
110 lues are factorized as a product between the additive model matrix and the h - 1 additive effects, an
111 e.g. maximum likelihood methods, generalized additive models, nonparametric kernel density estimators
112 CI], 1.82 to 3.26; P=1.42x10(-9); and in the additive model: odds ratio, 2.19; 95% CI, 1.66 to 2.90;
113            Titration experiments indicate an additive model of HIPK3-T splicing activation, requiring
114         Quantitative trait analysis with the additive model of inheritance was analyzed using linear
115 although the TDT can perform better under an additive model of inheritance.
116          A physically motivated, nonpairwise-additive model of water-mediated interactions added to a
117 tivariate system, assuming an infinitesimal, additive, model of inheritance.
118 curve during an oral glucose tolerance test (additive model, P = 0.022; dominant model, P = 0.010).
119 R8 rs3764880-G (recessive model: p = 0.0173; additive model: p = 0.0161) were associated with pericar
120 cted mortality under medical treatment, with additive model predictive value (all, p </= 0.04) and a
121  by proportional hazards using a generalized additive models procedure.
122                                           An additive model, rather than a multiplicative or contrast
123        We also note that, under dominant and additive models, regardless of the statistic used, pedig
124                                  Generalized additive models revealed that long-term increase in Vibr
125                    Multivariable generalized additive models showed that RTL did not differ between c
126                         Predictions from the additive model significantly overshot the actual respons
127          Data were analyzed with generalized additive models (smoothing).
128                                           An additive model specifies that the disutility of costs is
129                                  Generalized additive models supported a linear association between e
130 ted SAR cases was analysed using generalized additive models, taking into account confounding factors
131                 Instead, the data support an additive model that best captures abnormal neural patter
132                          Using a generalized additive model that controlled for season, region, and l
133                                     While in additive models the mutational covariance matrix is alwa
134                            By using a linear additive model, these 4 TH1 pathway SNPs cumulatively ex
135 ndard deviations were detected; but under an additive model, these did not fully account for the obse
136 ical content on temperature is improved over additive models, though further sampling is required to
137 nalysis because current methods often use an additive model to analyze data.
138 ate holistic system indicator variables, non-additive modelling to estimate alternate attractors, and
139 rmed a retrospective study using generalized additive models to analyze three major livestock populat
140                  As a first approach, we use additive models to analyze two independent data sets (n
141                          We used generalised additive models to evaluate the quantitative relation be
142 x proportional hazard models and generalized additive models to examine multivariable-adjusted associ
143                          We used generalized additive models to examine the dose-response curve using
144  of field observations in the North Sea with additive models to infer spatiotemporal trends of chloro
145 d gene coexpression networks and generalized additive models to predict effects on reproduction in th
146                  Under various recessive and additive models, TRANSMIT was slightly more powerful tha
147 lies on the use of Time-Varying Group Sparse Additive Models (TV-GroupSpAM) for high-dimensional, fun
148                                    Using the additive model, two tightly linked functional SNPs in ER
149                          The validity of the additive model used in this analysis can be tested by de
150 ation studies on AWT were performed under an additive model using linear regression (adjusted for pac
151 d glaucoma was obtained with the generalized additive model using only three parameters (AROC = 0.854
152 est evidence of an FcgammaR-SLE association (additive model: V/V 176 versus V/F 176 OR 1.51, V/V 176
153  T. aestivum gene expression was compared to additive model values (mid-parent) calculated from paren
154 justed hazard ratio for each L allele in the additive model was 1.91 (1.20 to 3.06; P=0.01) for the r
155 ariance analysis indicated that a completely additive model was adequate to explain the variances obs
156 with fixed-effects meta-analysis assuming an additive model was used to test for associations.
157   Using the same covariates in a generalized additive model, we examined the shape of the relationshi
158 s of 272 UM cases and 1782 controls using an additive model, we identified five variants significantl
159                    In unadjusted generalized additive models, we observed a significant nonlinear rel
160 ographic and Health Surveys with generalized additive models, we quantify spatial patterns of measles
161 nfidence intervals) for each L allele in the additive model were 1.99 (1.27 to 3.14; P=0.003) for the
162              Synergistic interactions on the additive model were observed between heavy alcohol consu
163                                  Generalized additive models were used to estimate the amount of wate
164                                  Generalized additive models were used to estimate the association be
165                                  Generalized additive models were used to estimate the variation in s
166 tivariate linear, piecewise, and generalized additive models were used to examine dose-response relat
167                        Nonlinear generalized additive models were used to examine the association bet
168                                  Generalized additive models were used to examine the relationship be
169                                  Generalized additive models were used to identify structure in the r
170 nal study of 357 Yup'ik Eskimos, generalized additive models were used to plot covariate-adjusted ass
171                                  Generalized additive models were used to predict ASD odds across the
172                                  Generalized additive models were used to regress time series of dail
173                         Adjusted generalized additive models were used to smooth the association of p
174                                  Generalized additive models were used to test for threshold effects.
175 08 on 20p (location, chi = 19.5 cM) under an additive model, whereas the weighted MLS was 2.06 on 20q
176                                           An additive model, whereby fat is added to the waist and hi
177 polymorphisms (SNPs) and expression under an additive model, which ignores interaction and haplotypic
178 proportional hazards model and a generalized additive model with a logistic link.
179 Cox proportional hazards regression under an additive model with adjustment for age at onset, sex, an
180                                  A two-locus additive model with an additive x additive interaction o
181                     The accuracy of a simple additive model with peptide length correction (R(2) valu
182  APOL1 risk alleles were associated under an additive model with systolic blood pressure (SBP) and ag
183 tistic is increased by >20%, on average, for additive models with modest genotype relative risks.
184  present study, the authors used generalized additive models with nonparametric smoothing splines to
185 ted to trait and state anxiety using general additive models with penalized splines, while controllin
186   Logistic regression models and generalized additive models with thin-plate splines were fit to the

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