ライフサイエンスコーパス: adenine

1 ength of the DNA probe (six (A6) or 12 (A12) adenines).

2 at the primer terminus opposite cytosine and adenine.

3 troduction of the phosphonomethoxy group and adenine.

4 promised even with the addition of exogenous adenine.

5 hes guanine, much more so than its precursor adenine.

6 also evaluated according to the detection of adenine.

7 9) adenine adducts and di-ribosylated N(6,9) adenine.

8 used for electrochemical characterization of adenine.

9 overpotential for the oxidation reaction of adenine.

10 obalamin, in which the lower axial ligand is adenine.

11 icin loop (SRL) where it cleaves a conserved adenine.

12 owed by mass spectrometric quantification of adenine.

13 y-2'-[(18)F]fluoro-9-beta-d-arabinofuranosyl-adenine ([(18)F]CFA) and 2'-deoxy-2'-[(18)F]fluoro-9-bet

14 Inhibition of PI3K activity by 3-methyl adenine (3-MA), Wortmannin (WM) and LY294002 (LY) increa

15 he Dnmt2 tRNA methyltransferase, the Mettl4 (adenine-6) DNA methyltransferase, and the Tet DNA demeth

16 Fe3O4 NPs-GO/CPE) for sensitive detection of adenine (A) and guanine (G).

17 However, excitation of a guanine (G) adenine (A) sequence leads to reformation of the intact

18 es (tNTPs) bearing the four genetic bases of adenine (A), cytosine (C), thymine (T), and guanine (G).

19 raction between four single DNA nucleotides (Adenine (A), Guanine (G), Cytosine (C), and Thymine (T))

20 Guanine (G), adenine (A), thymine (T), and cytosine (C) are the four

21 lated and methylene blue (MB)-modified oligo-adenine (A)-guanine (G) DNA probe.

22 etrahydrofuranyl abasic sites replacing loop adenines (A/AP) and tetrad guanines (G/AP) in quadruplex

23 s products of mono-ribosylated N(6) and N(9) adenine adducts and di-ribosylated N(6,9) adenine.

24 t experiment we show that photoexcitation of adenine adjacent to a CPD has no influence on this lesio

25 expand the base-base FRET repertoire with an adenine analogue FRET-pair.

26 ults in the highest average brightness of an adenine analogue inside DNA.

27 ielding route, and both constitute excellent adenine analogues.

28 udies are consistent with the association of adenine and cyanuric acid units into a hexameric rosette

29 methylation at the hydrogen bonding edge of adenine and guanine in mRNA affects translation.

30 everal purine pathway mutants, some in which adenine and guanine nucleotide metabolism is uncoupled.

31 gossypii, we demonstrate that the binding of adenine and guanine nucleotides to the canonical nucleot

32 Adenine and N(4)-acetylcytidine, nucleotide-derived meta

33 vel alternative over the previously reported adenine and pteridone type of agonists.

34 stitution, 5'-esters, deaza modifications of adenine, and ribose restored in place of methanocarba.

35 ine xCT 3'-UTR identified numerous copies of adenine- and uridine-rich elements, raising the possibil

36 with the three known antitrypanosomal agents adenine arabinoside, tubercidin, and cordycepin, or they

37 orbance spectra for reactant MTA and product adenine are similar.

38 egioselective, giving the N-9 nucleotide for adenine as a major product.

39 tation in ATTR where tyrosine is replaced by adenine at position 60.

40 While never shown, protonation of adenines at position N1 has been hypothesized to be crit

41 We found that an ade13Delta mutant is an adenine auxotroph and is unable to successfully cause in

42 g MS (Ppmet6) exhibits methionine as well as adenine auxotrophy indicating that MS is required for me

43 vels and is unable to reverse methionine and adenine auxotrophy of Ppmet6 Thus, nuclear localization

44 Here we describe adenine base editors (ABEs) that mediate the conversion

45 y the slide parameter in the central thymine-adenine base pairs; we also detect 'dynamic' deformation

46 ucleophile on the same side as the departing adenine base.

47 tructure-activity relationship assessment of adenine-based inhibitors using biochemical and docking m

48 s-strand hydrogen bonds mostly involving the adenine bases of the G.A and A.G pairs.

49 hat MS is required for methionine as well as adenine biosynthesis.

50 sertion of 8-oxoG is mutagenic when opposite adenine but not when opposite cytosine.

51 ose selectively formed mono-ribosylated N(6) adenine, but in the presence of (Ade)2Cu complex the rea

52 respond normally to cytosolic Ca(2+) , ATP, adenine, caffeine and to luminal Ca(2+) .

53 adjustment to the aptamer (2AP exchanged for adenine) can increase its specificity for cocaine in phy

54 des and was concentrated in dense methylated adenine clusters surrounding the transcriptional start s

55 s inhibited by both chloroquine and 3-methyl adenine, consistent with trafficking of ER TG through th

56 Especially the adenine containing analogue (PMDTA) was endowed with pot

57 a suggest that perturbation of intracellular adenine-containing nucleotide pools provides a crucial s

58 thdrawing groups at several positions in the adenine core enhance potency.

59 taining 10 deoxy-ribonucleotides of thymine, adenine, cytosine, or guanine results in the growth of f

60 equently, T. brucei grown in the presence of adenine demonstrated increased sensitivity to deoxyadeno

61 lculating relative binding affinities for 23 adenine derivatives, resulting in strong agreement with

62 on Au(111) of (RS)-N(9)-(2,3-dihydroxypropyl)adenine (DHPA), a plausibly prebiotic nucleoside analog

63 Here, we report that adenine, diaminopurine, and hypoxanthine nucleoside phos

64 in two independent models of renal failure, adenine diet induced and 5/6 nephrectomy.

65 re, as measured by BUN levels in mice fed an adenine diet known to cause renal injury followed by fib

66 ide(+) (NAD(+))/reduced form of nicotinamide adenine dinucleotid (NADH) ratio and the NAD(+)-dependen

67 Blue light using flavin adenine dinucleotide (BLUF) proteins are essential for t

68 the direct precursor of the cofactors flavin adenine dinucleotide (FAD) and flavin mononucleotide (FM

69 The riboflavin (RF) cofactors, flavin adenine dinucleotide (FAD) and flavin mononucleotide (FM

70 Flavin-adenine dinucleotide (FAD) dependent glucose dehydrogena

71 h a decrease in the cellular level of flavin adenine dinucleotide (FAD), a metabolic cofactor of LSD1

72 c crystal structures of the catalytic flavin adenine dinucleotide (FAD)- and heme-binding domains of

73 inucleotide (phosphate) (NAD(P)H) and flavin adenine dinucleotide (FAD).

74 ylates the pyridinium ring of nicotinic acid adenine dinucleotide (NaAD) and cleaves the phosphoanhyd

75 We also report that nicotinic acid adenine dinucleotide (NAAD), which was not thought to be

76 man fatty liver, lowers hepatic nicotinamide adenine dinucleotide (NAD(+) ) levels driving reductions

77 dox reactions: oxidized/reduced nicotinamide adenine dinucleotide (NAD(+) and NADH) and nicotinamide

78 e oxidized and reduced forms of nicotinamide adenine dinucleotide (NAD(+) and NADH), oxidized and red

79 rmediate in the biosynthesis of nicotinamide adenine dinucleotide (NAD(+)) and its derivatives in all

80 ADH and its cofactor nicotinamide adenine dinucleotide (NAD(+)) are immobilized onto the O

81 u-H intermediate using oxidized nicotinamide adenine dinucleotide (NAD(+)) as the H(-) source, howeve

82 n mRNAs can also carry a 5' end nicotinamide adenine dinucleotide (NAD(+)) cap that, in contrast to t

83 Nicotinamide adenine dinucleotide (NAD(+)) is an essential substrate

84 and oxidative stress response, nicotinamide adenine dinucleotide (NAD(+)) is emerging as a metabolic

85 ibose from the oxidized form of nicotinamide adenine dinucleotide (NAD(+)) onto substrate proteins.

86 Nicotinamide adenine dinucleotide (NAD(+)) participates in intracellu

87 uding the recently described 5' nicotinamide-adenine dinucleotide (NAD(+)) RNA in bacteria.

88 ich ADP-ribosyltransferases use nicotinamide adenine dinucleotide (NAD(+)) to modify target proteins

89 ratio of the amount of oxidized nicotinamide adenine dinucleotide (NAD(+)) to that of its reduced for

90 ecently, cellular production of nicotinamide adenine dinucleotide (NAD(+)) via nicotinamide phosphori

91 is the sirtuin (SIRT) family of nicotinamide adenine dinucleotide (NAD(+))-dependent deacetylases.

92 metabolic pathways regulated by nicotinamide adenine dinucleotide (NAD(+)).

93 nction, via increased levels of nicotinamide adenine dinucleotide (NAD(+)).

94 Retinal levels of nicotinamide adenine dinucleotide (NAD(+), a key molecule in energy a

95 overy from injury by regulating nicotinamide adenine dinucleotide (NAD) biosynthesis.

96 Stx2a predominantly altered the nicotinamide adenine dinucleotide (NAD) cofactor pathway and the infl

97 the precursor of the universal nicotinamide adenine dinucleotide (NAD) cofactor.

98 eneration, the concentration of nicotinamide adenine dinucleotide (NAD) falls, at least in part due t

99 Nicotinamide adenine dinucleotide (NAD) is produced via de novo biosy

100 Nicotinamide adenine dinucleotide (NAD) is synthesized de novo from t

101 ROUND & AIMS: The mitochondrial nicotinamide adenine dinucleotide (NAD) kinase (NADK2, also called MN

102 plements boosting intracellular nicotinamide adenine dinucleotide (NAD) levels, thus preventing or am

103 ubisco from the C4 grasses with nicotinamide adenine dinucleotide (NAD) phosphate malic enzyme (NADP-

104 ude the adduct of glutamate and nicotinamide adenine dinucleotide (NAD), fragments of NAD detected in

105 Here, we report that the nicotinamide adenine dinucleotide (NAD)-dependent deacetylase SIRT1 a

106 2 (SIRT2), one of the mammalian nicotinamide adenine dinucleotide (NAD)-dependent lysine deacylases,

107 in situ chemical species (beta-nicotinamide adenine dinucleotide (NADH) and H2O2) acting as coreacta

108 o form l-lactate, using reduced nicotinamide adenine dinucleotide (NADH) as the cofactor.

109 Reduced nicotinamide adenine dinucleotide (NADH) can generate a ruthenium-hyd

110 opose that the reduced cofactor nicotinamide adenine dinucleotide (NADH) is a possible hydride source

111 Nicotinamide Adenine Dinucleotide (NADH) is an important coenzyme in

112 profiles of tryptophan, reduced nicotinamide adenine dinucleotide (NADH), and flavin denine dinucleot

113 Autofluorescence, attributed to nicotinamide adenine dinucleotide (NADH), was induced by two-photon l

114 material for the development of nicotinamide adenine dinucleotide (NADH)-based biosensors.

115 es, such as the reduced form of nicotinamide adenine dinucleotide (NADH).

116 d the reduced/oxidized ratio of nicotinamide adenine dinucleotide (NADH/NAD(+) ratio) and protein ace

117 ogenous fluorescence of reduced nicotinamide adenine dinucleotide (phosphate) (NAD(P)H) and flavin ad

118 FLIM of autofluorescent reduced nicotinamide adenine dinucleotide (phosphate), NAD(P)H, has been prev

119 mide adenine dinucleotide phosphate , flavin adenine dinucleotide , glutathione disulfide/glutathione

120 /adenosine monophosphate [AMP], nicotinamide adenine dinucleotide /NAD, nicotinamide adenine dinucleo

121 n-canonical mechanism that uses nicotinamide adenine dinucleotide as a cofactor.

122 dation of d-lactate to pyruvate using flavin adenine dinucleotide as a cofactor; knowledge of its fun

123 In the presence of beta-nicotinamide adenine dinucleotide as cofactor, and ethanol as fuel, t

124 phosphorylating nicotinamide/nicotinic acid adenine dinucleotide at the adenosine 3'-hydroxyl group.

125 vation, electron transfer between the flavin adenine dinucleotide cofactor and tryptophan residues le

126 hondrial calcium content and in nicotinamide adenine dinucleotide fluorescence following pacing and 2

127 neuronal survival by enhancing nicotinamide adenine dinucleotide flux in injured neurons.

128 ential, associated with reduced nicotinamide adenine dinucleotide metabolism and altered citric acid

129 ts of AvrRxo1, 3'-NADP and 3'-nicotinic acid adenine dinucleotide phosphate (3'-NAADP), are substanti

130 Nicotinic acid adenine dinucleotide phosphate (NAADP) and cyclic ADP-ri

131 Nicotinic acid adenine dinucleotide phosphate (NAADP) potently releases

132 Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) stimulates calciu

133 Nicotinic acid adenine dinucleotide phosphate (NAADP), the most potent

134 , oxidized and reduced forms of nicotinamide adenine dinucleotide phosphate (NADP(+) and NADPH), and

135 ucleotide (NAD(+) and NADH) and nicotinamide adenine dinucleotide phosphate (NADP(+) and NADPH); coen

136 strates and the reduced form of nicotinamide adenine dinucleotide phosphate (NADPH) as co-factor.

137 e synthesis and regeneration of nicotinamide adenine dinucleotide phosphate (NADPH) in p53-deficient

138 Reduced nicotinamide adenine dinucleotide phosphate (NADPH) is essential for

139 we show that antibiotics rescue nicotinamide adenine dinucleotide phosphate (NADPH) oxidase 2 (Nox2)-

140 S was generated through reduced nicotinamide adenine dinucleotide phosphate (NADPH) oxidase activatio

141 xhibited reduced (hydrogenated) nicotinamide adenine dinucleotide phosphate (NADPH) oxidase activity

142 n, activating integrin-mediated nicotinamide adenine dinucleotide phosphate (NADPH) oxidase-2 (NOX-2)

143 Nicotinamide adenine dinucleotide phosphate (NADPH) oxidases produce

144 lytic anemia linked to impaired nicotinamide adenine dinucleotide phosphate (NADPH) production and im

145 denine dinucleotide phosphate / nicotinamide adenine dinucleotide phosphate , flavin adenine dinucleo

146 mide adenine dinucleotide /NAD, nicotinamide adenine dinucleotide phosphate / nicotinamide adenine di

147 ein kinase II), which decreases nicotinamide adenine dinucleotide phosphate hydrogen synthesis, there

148 Defects in phagocytic nicotinamide adenine dinucleotide phosphate oxidase 2 (NOX2) function

149 n directly decreases myocardial nicotinamide adenine dinucleotide phosphate oxidase activity via endo

150 iponectin suppresses myocardial nicotinamide adenine dinucleotide phosphate oxidase activity, by prev

151 gh neurohormonal activation of (nicotinamide adenine dinucleotide phosphate oxidase dependent) oxidat

152 ice, genetic deficiency of gp91 nicotinamide adenine dinucleotide phosphate oxidase subunit-2 prevent

153 Adult rats; wild-type/nicotinamide adenine dinucleotide phosphate oxidase subunit-2-deficie

154 sensitivity is associated with nicotinamide adenine dinucleotide phosphate oxidase subunit-2-mediate

155 The NOX (nicotinamide adenine dinucleotide phosphate oxidase) family includes

156 ctin) led to reduced myocardial nicotinamide adenine dinucleotide phosphate oxidase-derived O2 (-), w

157 ffectors such as Rho kinase and nicotinamide adenine dinucleotide phosphate oxidases are also inhibit

158 nvestigate the possible role of nicotinamide adenine dinucleotide phosphate reduced form oxidases (NO

159 include NADPH (reduced form of nicotinamide adenine dinucleotide phosphate) oxidase, xanthine oxidas

160 ility to NADPH (reduced form of nicotinamide adenine dinucleotide phosphate) oxidase-dependent killin

161 tors adenosine triphosphate and nicotinamide adenine dinucleotide phosphate, and have become attracti

162 g and oxidizing glutathione and nicotinamide adenine dinucleotide phosphate, and significantly down-r

163 ium release channels gated by nicotinic acid adenine dinucleotide phosphate, as also as intracellular

164 tinamide adenine nucleotide and nicotinamide adenine dinucleotide phosphate, respectively) serving as

165 The three IDH isoforms (nicotinamide adenine dinucleotide phosphate-dependent IDH1 and IDH2,

166 or acetylcholinesterase (AChE), nicotinamide adenine dinucleotide phosphate-diaphorase (NADPH-d), glu

167 /stromal cell therapy decreased nicotinamide adenine dinucleotide phosphate-oxidase 2 and inducible n

168 yme activity, cellular oxidized nicotinamide adenine dinucleotide phosphate/NADPH levels, phagocytic

169 on electron microscopy, and 3) nicotinamide adenine dinucleotide redox potential and adenosine triph

170 OS production by downregulating nicotinamide adenine dinucleotide(+) (NAD(+))/reduced form of nicotin

171 n VVD residue Cys108 and its cofactor flavin adenine dinucleotide(FAD), and prompts VVD switching fro

172 Ds are NAD(+) (oxidized form of nicotinamide adenine dinucleotide) binding domains that regulate prot

173 M (S-adenosyl methionine), NAD (nicotinamide adenine dinucleotide), and FAD (flavin adenine dinucleot

174 ctivity of the NAD(+) (oxidized nicotinamide adenine dinucleotide)-dependent deacetylase Sir2.

175 amide adenine dinucleotide), and FAD (flavin adenine dinucleotide).

176 ular adenosine triphosphate and nicotinamide adenine dinucleotide, both pathways converging in the fo

177 dial levels of 3 metabolites, nicotinic acid adenine dinucleotide, methylnicotinamide, and N1-methyl-

178 irt3 because of increased NADH (nicotinamide adenine dinucleotide, reduced form) and acetyl-CoA level

179 or of flavin mononucleotide (FMN) and flavin adenine dinucleotide, which are essential coenzymes in a

180 amily is that the sequence of the key flavin adenine dinucleotide-binding domain is split into at lea

181 Sirtuin 1 (SIRT1) is a nicotinamide adenine dinucleotide-dependent deacetylase, and its dysr

182 te-dependent IDH1 and IDH2, and nicotinamide adenine dinucleotide-dependent IDH3) contribute to regul

183 es, such as the reduced form of nicotinamide adenine dinucleotide.

184 FeS and glycerol-dehydrogenase/nicotinamide-adenine-dinucleotide (GlDH-NAD(+)) apoenzyme-coenzyme mo

185 The bacterial MutY (MUTYH in humans) adenine DNA glycosylase is able to initiate the repair o

186 ments of 8-oxoguanine DNA glycosylase, alkyl-adenine DNA glycosylase, MutY DNA glycosylase, uracil DN

187 nvolved in heme biogenesis or to function as adenine DNA methyltransferase.

188 These uracil lesions base-pair with adenines during the completion of reverse transcription

189 ene-modified electrodes in comparison to the adenine-enriched unmethylated DNA.

190 sine by the ability to cleave it and use the adenine for ATP synthesis.

191 hine, hypoxanthine, glucose, malic acid, and adenine) form the basis for an accurate classification/r

192 ased on the interactions between Au(III) and adenine; formation of these complexes rigidifies the met

193 ycosylases prevent DNA mutations by excising adenine from promutagenic 8-oxo-7,8-dihydroguanine (OG):

194 osomal-stalk P-proteins to remove a specific adenine from the sarcin/ricin loop.

195 Adenine-functionalized spongy graphene (FSG) composite,

196 ored under refrigerated conditions in saline adenine glucose mannitol (SAGM) additives have revealed

197 MutY adenine glycosylases prevent DNA mutations by excising a

198 asures that are associated with the cytosine-adenine-guanine (CAG) expansion in individuals before di

199 Although adenine has been previously implicated as a general acid

200 The current techniques for determining adenine have several shortcomings such as high cost, hig

201 cal signals ascribed to guanine/xanthine and adenine/hypoxanthine in human hepatoma (HepG2) cells wer

202 We provide evidence that the adenine immediately 3' to the scissile phosphate (A1) ac

203 8 was demonstrated to specifically methylate adenine in 5'CCCGA and 5'CCTGA sequences.

204 rases, but no enzymes are known to deaminate adenine in DNA.

205 We also noticed that low amounts of adenine in media could lead to higher levels of mitochon

206 ible methylation of the N6 or N1 position of adenine in RNA has recently been shown to play significa

207 s that modify cytosine in one DNA strand and adenine in the opposite strand for host protection.

208 ermore, the reaction of 2-furanmethanol with adenine in the presence of ribose generated kinetin and

209 nsor showed good sensitivity for determining adenine in two ranges from 0.1-1 and 1-10 muM, with a de

210 tracts of rhubarb in a rat model of CRF with adenine-induced chronic tubulointerstitial nephropathy.

211 disorders in key metabolites associated with adenine-induced CRF.

212 In adenine-induced uremia, only a modest increase in serum

213 n genetically modified mice without and with adenine-induced uremia.

214 One of the reaction products, adenine, inhibited the enzyme, which might explain why T

215 ion of target DNA and flipping of the target adenines into extra-helical positions.

216 single HG bp trapped using the N1-methylated adenine (m1A) lesion affects the structural and dynamic

217 tic pressure is severely compromised without adenine methylation at GATC sites.

218 lled by the LysR-type factor OxyR and by DNA adenine methylation.

219 Although the adenine methylome remains stable during drug stress, wit

220 Short-term expression of the bacterial DNA adenine methyltransferase Dam, tethered to the Gad1 gene

221 ic and drug-resistant clinical isolates, DNA adenine methyltransferase deficiency potentiates antibio

222 Neuronal genome tagging in vivo by Mef2c-Dam adenine methyltransferase fusion protein confirmed the l

223 show the results and the validation of a DNA adenine methyltransferase identification (DamID) genome-

224 dition, we examined a number of cytosine and adenine methyltransferases to generate double base modif

225 A novel DNA adenine modification, N(6)-methyladenine (6mA), has rece

226 In particular, deamination of adenine moiety in (deoxy)nucleoside triphosphates, resul

227 Substrate binding of the adenine moiety is mediated almost exclusively by hydroge

228 cted sharing of a proton with atom N7 of the adenine moiety possessing unconventional hydrogen-bond g

229 nsgenic expression of bacterial nicotinamide adenine mononucleotide (NMN) in zebrafish and mice, whic

230 acid catalysis through the N3 position of an adenine nucleobase, thus expanding the repertoire of kno

231 and NADPH (the reduced forms of nicotinamide adenine nucleotide and nicotinamide adenine dinucleotide

232 ulated reperfusion model, a similar trend in adenine nucleotide changes was observed.

233 e 4B (PDE4B) without affecting intracellular adenine nucleotide concentrations.

234 embrane-trafficking machinery, and increased adenine nucleotide levels.

235 enzyme in complex with CoA and show that the adenine nucleotide of this cofactor is bound in a distin

236 -regulated to control the size of the matrix adenine nucleotide pool in response to cellular energeti

237 Adenine nucleotide translocase (ANT) exchanges ADP/ATP t

238 Members of the adenine nucleotide translocase (ANT) family exchange ADP

239 ondria, to interact with and dephosphorylate adenine nucleotide translocase 1 (ANT1), a central molec

240 This study provides evidence for a role of adenine nucleotide translocase in the mechanism underlyi

241 ation/knockdown-induced dysregulation in the adenine nucleotide translocase, which results in a slowe

242 e for cytosolic ADP(3-) via the electrogenic adenine nucleotide translocator (ANT) located in the mit

243 n heavy chain-alpha, cardiac troponin-I, and adenine nucleotide translocator 1 (ANT1), have been iden

244 rmed in mice in which the heart-muscle-brain adenine nucleotide translocator isoform 1 (ANT1) was ina

245 acers strands comprised of phosphorothioated adenine nucleotides (A15*).

246 Adenine nucleotides and nucleosides act on purinoceptors

247 and substrate-binding domain) in response to adenine nucleotides and substrates.

248 arginase 1, asymmetric dimethylarginine, and adenine nucleotides are all products of hemolysis that p

249 also indicate that MMS-induced mutations at adenine nucleotides are significantly enriched on the no

250 Levels of adenine nucleotides change rapidly after reperfusion and

251 Cells release adenine nucleotides into the extracellular space, where

252 Mitochondrial ATP-Mg/Pi carriers import adenine nucleotides into the mitochondrial matrix and ex

253 A rapid shift toward higher energy adenine nucleotides was observed following clinical repe

254 llular metabolism to the membrane by sensing adenine nucleotides, and are thus instrumental in mediat

255 104 functions at the physiological levels of adenine nucleotides.

256 it confers energy sensor function by binding adenine nucleotides.

257 mber of novel hybrid compounds combining the adenine nucleus with a suitable H2S slow-releasing moiet

258 ructure suggest that N1 is protonated on the adenines of every other rAMP-rAMP helix base pair.

259 ferred enhanced cardioprotection compared to adenine or 4-hydroxythiobenzamide.

260 ous electrophiles, model systems composed of adenine or adenosine, glycine, ribose and/or 2-furanmeth

261 g amino acids and other nutrients (inositol, adenine, or p-aminobenzoic acid) in the transformation m

262 d with the acceptor and donor of our current adenine pair, respectively.

263 ard synthesis of a 3'-fluoro-3'-deoxytetrose adenine phosphonate and can be expanded toward the synth

264 nthetic route to a 3'-fluoro-3'-deoxytetrose adenine phosphonate has been developed.

265 opurine as a fluorescent substrate for yeast adenine phosphoribosyltransferase.

266 nsient absorption spectra of DPA(-*) and the adenine polaron (An(+*)) are observed.

267 reprogrammes the assembly of unmodified poly(adenine) (poly(A)) into stable, long and abundant fibres

268 In the presence of adenine, projection of the SHAPE-directed sampling corre

269 ng methylation of the N6 and N1 positions in adenine, pseudouridylation, and methylation of carbon 5

270 for HP resistance identified Mrr (Methylated adenine Recognition and Restriction), a Type IV restrict

271 olysis products corroborates a mechanism for adenine removal with retention of stereochemistry.

272 olving general-acid catalysis by a conserved adenine residue in the active site.

273 NA N-glycosidases that depurinate a specific adenine residue in the conserved sarcin/ricin loop of 28

274 of the Bordetella phage DGR is primed by an adenine residue in TR RNA and is dependent on the DGR-en

275 age at Ap sites in duplex DNA can react with adenine residues on the opposing strand to generate a co

276 and quantification were 12.5 and 37.8 nmol/L adenine, respectively.

277 has a strong preference for DMB-ribose over adenine-ribose as substrate.

278 proach by determining four structures of the adenine riboswitch aptamer domain during the course of a

279 lded and highly extended conformations of an adenine riboswitch aptamer.

280 formational map of the Vibrio vulnificus add adenine riboswitch that reveals five classes of structur

281 approach that uses DpnI to cleave methylated adenine sites in duplex DNA.

282 Adenine-specific mutagenesis occurs during reverse trans

283 t binding is biased toward occupation of the adenine subpocket of the AcCoA binding site by an aromat

284 ated by the viral DNA-sensing cyclic guanine adenine synthase (cGAS) was severely compromised for the

285 ine exclusively were formed by replacing the adenine target recognition domain (TRD) with a cytosine-

286 e main routes for the reaction of (*)OH with adenine, the present work demonstrates that the OH radic

287 de phosphonates with the natural nucleobases adenine, thymine, cytosine, and guanosine has been perfo

288 nine-cytosine (G-C) base pair by zero-to-six adenine-thymine (A-T) base pairs has been investigated.

289 1), adding more stability than an additional adenine-thymine base-pairing interaction, 2.7 kJmol(-1).

290 We identify adenine-thymine-rich interactive domain-3a (Arid3a), a f

291 A recent study shows that methylation of adenine to form N (6)-methyladenine is a rare but readil

292 ly conserved catalytic motif IV and modifies adenine to m6A, and one having an NPPY catalytic motif I

293 R) to a variable repeat (VR) that results in adenine-to-random nucleotide conversions.

294 the presence of RecQ helicase and saturating adenine triphosphate let us deduce that RecQ binds to ss

295 We map three cytosine variants and two adenine variants.

296 The amount of adenine was used to calculate DNA quantity per 3.2 mm DB

297 genomes, we observed that up to 2.8% of all adenines were methylated in early-diverging fungi, far e

298 ric behavior of electrochemical oxidation of adenine, which was indicated by the improvement of anodi

299 l uridines at position -2 relative to the BP adenines, with efficient U2 base-pairing interactions pr

300 The deamination of adenine yields inosine, which is treated as guanine by p