1 monstrated that both variants have a reduced
adenine glycosylase activity and affinity for substrate
2 alanine by site-directed mutagenesis reduces
adenine glycosylase activity of MutY toward OG:A and G:A
3 cognition of substrate DNA necessary for the
adenine glycosylase activity of MutY.
4 s in E.coli MutY revealed a reduction in the
adenine glycosylase activity of the enzymes.
5 Previously, our laboratory analyzed the
adenine glycosylase activity of the homologous variant E
6 Assays of
adenine glycosylase activity of the Tyr82Cys and Gly253A
7 The
adenine glycosylase activity on single-stranded DNA repo
8 MutY also exhibits
adenine glycosylase activity toward adenine in G:A and C
9 This implies that the reduced
adenine glycosylase activity translates to a reduced cap
10 ecombinant MutY(Dr) expressed in E. coli has
adenine glycosylase activity with A/G, A/C, and A/GO mis
11 tant could still bind DNA substrates and had
adenine glycosylase activity.
12 tro studies show that the p26 domain retains
adenine glycosylase and AP lyase activity on DNA contain
13 of SpMYH expressed in yeast cells had normal
adenine glycosylase and DNA binding activities.
14 h lack the cluster are unable to perform the
adenine glycosylase function and bind to DNA.
15 MutY is an
adenine glycosylase in the base excision repair (BER) su
16 MutY, an
adenine glycosylase,
initiates the critical repair of an
17 The Escherichia coli
adenine glycosylase MutY and its human homolog (hMYH) pl
18 The E. coli
adenine glycosylase MutY is a member of the base excisio
19 The Escherichia coli
adenine glycosylase MutY is involved in the repair of 7,
20 The Escherichia coli
adenine glycosylase MutY is involved in the repair of 7,
21 The
adenine glycosylase MutY, which removes misincorporated
22 tures of the catalytic mechanism used by the
adenine glycosylase MutY.
23 The Escherichia coli MutY
adenine glycosylase plays a critical role in repairing m
24 MutY
adenine glycosylases prevent DNA mutations by excising a
25 G:A or G:A substrate, the time course of the
adenine glycosylase reaction exhibits biphasic kinetic b