ライフサイエンスコーパス: adenine moiety

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1 her functionalities at the 2-position of the adenine moiety.

2 dA:dC mismatches in duplex DNA, excising the adenine moiety.

3 n fold motif) as the-site for binding of the adenine moiety.

4 oribose (2'-P-cADPR), cyclized at N-1 of the adenine moiety.

5 ere is reason to believe that binding of the adenine moiety also involves a beta-sheet region located

6 e stacking of Tyr-245 side chain against the adenine moiety, an interaction seen in the structure of

7 s a cosolvent disrupts pi-pi stacking of the adenine moieties and causes the excimer states in all fi

8 ue to the slower ET dynamics (2 ns) with the adenine moiety and a faster ET dynamics (250 ps) with th

9 highly selective for ATP, and that both the adenine moiety and the beta-phosphate contribute to spec

10 eatured interactions of TM3 (His95) with the adenine moiety and TMs 6 and 7 with the ribose 5'-region

11 the A-loop (a small loop near the nucleotide adenine moiety), and the P-loop.

12 sugar puckering), non-glycosyl bonds to the adenine moiety, and a phosphate group shift.

13 nd Gln-92 in TM3 interact with the adenosine adenine moiety, and Leu-88 and Pro-86 play roles in conf

14 points toward an alpha-helix involved in the adenine moiety binding as a participant of this communic

15 volved in forming the binding pocket for the adenine moiety differ substantially both from the previo

16 diverse pharmacophore motifs for binding the adenine moiety, fewer, but still diverse, motifs for nic

17 in part due to the MTAP-dependent salvage of adenine moieties from endogenously generated MTA, becaus

18 In particular, deamination of adenine moiety in (deoxy)nucleoside triphosphates, resul

19 ydroquinone states donate an electron to the adenine moiety in 12 ps and 2 ns, respectively.

20 miquinone states absorb an electron from the adenine moiety in 19 and 135 ps, whereas the excited ani

21 r electron transfer between the ring and the adenine moiety in 5-9 ps as well as subsequent charge re

22 Substrate binding of the adenine moiety is mediated almost exclusively by hydroge

23 denosine also are bound, indicating that the adenine moiety is the primary positive determinant of li

24 with the substrate, whereas the intervening adenine moiety mediates electron tunneling for repair of

25 ransfer (ET) dynamics between the flavin and adenine moieties of flavin adenine dinucleotide in four

26 ts suggest that specific interaction between adenine moieties of Poly A nanocapsules and thymine/urac

27 ilized by base-pair interactions between the adenine moieties of the bound AcCoA molecules.

28 the closed form is highly specific with the adenine moiety of a substrate as the main recognition fa

29 n atoms closely corresponded when the docked adenine moiety of agonists and 1 were overlaid.

30 olecular determinants for recognition of the adenine moiety of ATP by proteins.

31 f the molecular basis for recognition of the adenine moiety of ATP in proteins will directly impact m

32 actions) to the overall binding force of the adenine moiety of ATP in proteins.

33 )methane 2 complementarily H-bond paired the adenine moiety of ATP, the boronic acid substituent of t

34 ogen bond between the hinge backbone and the adenine moiety of ATP.

35 how that under these conditions, ET from the adenine moiety of FAD becomes a competitive relaxation p

36 ng are limited to the residues that bind the adenine moiety of NAD(+).

37 37 with a 90 degrees rotation related to the adenine moiety of NAD, concomitant with clamping the act

38 trajectory of IDH was modified (i) after the adenine moiety of nicotinamide adenine dinucleotide phos

39 n isoleucine residue that interacts with the adenine moiety of the NAD(+) cofactor, 20 A from the nic

40 Significantly, we found that the adenine moiety of the unusual bent flavin cofactor is es

41 cted sharing of a proton with atom N7 of the adenine moiety possessing unconventional hydrogen-bond g

42 cer chain linking bisphosphate groups to the adenine moiety provided many moderately potent antagonis

43 The ADP molecule is bound with its adenine moiety sandwiched between the side-chains of Arg

44 also employ protonation at N1 and N3 of the adenine moiety to activate the substrate during catalysi

45 ne diphosphate (ADP) and substitution of the adenine moiety to enhance affinity and selectivity for t

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