ライフサイエンスコーパス: adeno-associated virus

1 ll enough to be packaged efficiently into an adeno-associated virus.

2 er a single systemic delivery of recombinant adeno-associated virus.

3 ckout mice and mice injected with 3xMyc-FXR1 adeno-associated virus.

4 he murine heart was performed by means of an adeno-associated virus.

5 nd a donor template delivered by recombinant adeno-associated virus.

6 ns of somatic brain transgenesis mediated by adeno-associated virus.

7 2 and a reporter through the injection of an adeno-associated virus.

8 d safety of gene therapy through infusion of adeno-associated virus 1 (AAV1)/SERCA2a in patients with

9 time mice were intracranially injected with adeno-associated virus 1 expressing murine IL-6 (AAV1-mI

10 Adeno-associated virus 2 (AAV2) and adenovirus 5 (Ad5) a

11 been studied mostly in the dependoparvovirus adeno-associated virus 2 (AAV2) and the protoparvovirus

12 Adeno-associated virus 2 (AAV2) depends on the simultane

13 che for either virus to replicate.IMPORTANCE Adeno-associated virus 2 (AAV2) differs from most other

14 On the other hand, adeno-associated virus 2 (AAV2) is a helper-dependent de

15 ector, rAAV2/HBoV1, in which the recombinant adeno-associated virus 2 (rAAV2) genome is pseudopackage

16 Both adeno-associated virus 2 and adenovirus 5 are currently

17 Suppression of Sema3e using adeno-associated virus 2 carrying short hairpin RNA targ

18 efficacy of gene therapy with a recombinant adeno-associated virus 2/2 (rAAV2/2) vector carrying the

19 AMT-060 combines an adeno-associated virus-5 (AAV5) vector with a liver-spec

20 lso was performed in mice given infusions of adeno-associated virus 6-NF-kappaB-luciferase, to assess

21 d by live imaging of mice given infusions of adeno-associated virus 6-NF-kappaB-luciferase.

22 ntrols, were given injections of recombinant adeno-associated virus 8 vector that expressed the prima

23 In proof-of-concept experiments, we used Adeno-Associated Virus 9 (AAV9) to deliver single-guide

24 Similarly, adeno-associated virus 9 (AAV9)-mediated restoration of

25 or JNCL by generating two self-complementary adeno-associated virus 9 (scAAV9) constructs to address

26 livery approach using two self-complementary adeno-associated virus 9 (scAAV9) constructs to address

27 In the present study, we delivered adeno-associated virus 9 carrying green fluorescent prot

28 holesterolaemia liver chimeric mice using an adeno-associated virus 9-based gene therapy and restore

29 -type levels in a mouse model of I/R, as did adeno-associated virus 9-mediated ATF6 overexpression.

30 Adeno-associated virus 9-mediated Cdk5 inhibitory peptid

31 in postnatal muscle tissue in vivo, we used adeno-associated virus-9 (AAV9) to deliver gene-editing

32 Adeno-associated virus (AAV) -delivered gene therapy has

33 We applied STN-DBS in an adeno-associated virus (AAV) 1/2-driven human mutated A5

34 finger nuclease mRNA via electroporation and adeno-associated virus (AAV) 6 delivery of donor constru

35 , we assessed the therapeutic efficacy of an adeno-associated virus (AAV) 9-mbetagal vector infused s

36 ession in 1-month old mdx:utr (-/-) mice via adeno-associated virus (AAV) 9-mediated RNA interference

37 The use of adeno-associated virus (AAV) as a gene therapy vector ha

38 The Rep68 protein from adeno-associated virus (AAV) combines a DNA binding and

39 c applications that use the highly versatile adeno-associated virus (AAV) delivery vehicle.

40 ese cytokines in a murine model of CHB using adeno-associated virus (AAV) delivery.

41 g RNP delivery with naturally recombinogenic adeno-associated virus (AAV) donor vectors enables site-

42 Adeno-associated virus (AAV) effectively targets therape

43 icistronic gene transfer vector derived from Adeno-associated virus (AAV) enables a wide range of app

44 roteostasis in AMD, we delivered recombinant adeno-associated virus (AAV) encoding Abeta42 and Abeta4

45 Adeno-associated virus (AAV) entry is determined by its

46 Stable delivery of adeno-associated virus (AAV) expressing cKL to diabetic

47 The clinical utility of the adeno-associated virus (AAV) gene delivery system has be

48 fective therapy for corneal vascularization, adeno-associated virus (AAV) gene therapy, exploiting a

49 al cord via intrathecal administration of an adeno-associated virus (AAV) gene transfer vector signif

50 Adeno-associated virus (AAV) has become a popular and su

51 Adeno-associated virus (AAV) has become the vector of ch

52 Adeno-associated virus (AAV) has been shown to transduce

53 Gene delivery vectors based on adeno-associated virus (AAV) have been utilized in a lar

54 Viral vectors based on the adeno-associated virus (AAV) hold great promise for in v

55 CRISPR-Cas9 delivery by adeno-associated virus (AAV) holds promise for gene ther

56 n, we show that overexpression of Arg1 using adeno-associated virus (AAV) in the CNS of rTg4510 tau t

57 However, in vivo delivery of mAgrin via adeno-associated virus (AAV) into FKRP mutant mice was u

58 Adeno-associated virus (AAV) is a dependent virus of the

59 Adeno-associated virus (AAV) is a replication-deficient

60 Adeno-associated virus (AAV) is frequently used to manip

61 therapy using nonintegrating viruses such as adeno-associated virus (AAV) is not optimal in this sett

62 The life cycle of the human parvovirus adeno-associated virus (AAV) is orchestrated by four Rep

63 Intracellular transport of recombinant adeno-associated virus (AAV) is still incompletely under

64 Adeno-associated virus (AAV) is the only eukaryotic viru

65 Delivery by adeno-associated virus (AAV) of clustered regularly inte

66 Vectors based on adeno-associated virus (AAV) present a number of advanta

67 ating protein (AAP) is a recently discovered adeno-associated virus (AAV) protein that promotes capsi

68 e (ZFN) mRNA with donor template delivery by adeno-associated virus (AAV) serotype 6 vectors directs

69 Many adeno-associated virus (AAV) serotypes efficiently trans

70 placement of SDS-PAGE for purity analysis of adeno-associated virus (AAV) therapeutic products of dif

71 To this end, we created an adeno-associated virus (AAV) to express hGRbeta in the m

72 We used adeno-associated virus (AAV) to express these isoforms i

73 Using adeno-associated virus (AAV) to inhibit the calcineurin-

74 The ability to target the adeno-associated virus (AAV) to specific types of cells,

75 We have previously shown that the adeno-associated virus (AAV) variant, ShH10, transduces

76 previously reported compassionate use of an adeno-associated virus (AAV) vector containing the human

77 ateral subretinal injection of a recombinant adeno-associated virus (AAV) vector containing the RPE65

78 Following subretinal injection of an adeno-associated virus (AAV) vector encoding ARES, lucif

79 The adeno-associated virus (AAV) vector gene delivery system

80 ssion in the dorsal striatum, we injected an adeno-associated virus (AAV) vector producing a short ha

81 vity-dependent neurotrophic factor, using an adeno-associated virus (AAV) vector significantly increa

82 d for IDUA production and function following adeno-associated virus (AAV) vector transduction of MPS1

83 dministered a single intravenous dose of the adeno-associated virus (AAV) vector, AAV-BR1-CAG-NEMO, d

84 ed in the brains of transgenic mice using an adeno-associated virus (AAV) vector, decreased parenchym

85 ood, Crudele et al describe a novel study of adeno-associated virus (AAV) vector-mediated gene therap

86 age it with two gRNAs in a single functional adeno-associated virus (AAV) vector.

87 ) directed against CVB3 were delivered by an adeno-associated virus (AAV) vector.

88 Adeno-associated virus (AAV) vectors are currently being

89 Adeno-associated virus (AAV) vectors are currently the l

90 ants identified Anc80L65 from a set of other adeno-associated virus (AAV) vectors as a potent vector

91 Adeno-associated virus (AAV) vectors can stably express

92 reprogramming of MFs into hepatocytes using adeno-associated virus (AAV) vectors expressing hepatic

93 the astrocytic CN/NFAT pathway in rats using adeno-associated virus (AAV) vectors expressing the astr

94 Herein, we review the use of adeno-associated virus (AAV) vectors for delivery of HIV

95 We investigated adeno-associated virus (AAV) vectors for gene delivery t

96 Immune responses in gene therapy with adeno-associated virus (AAV) vectors have been the objec

97 Adeno-associated virus (AAV) vectors have been used succ

98 Adeno-associated virus (AAV) vectors have been widely ad

99 Adeno-associated virus (AAV) vectors have made great pro

100 eover, cardiac overexpression of HMGB1 using adeno-associated virus (AAV) vectors induced inflammatio

101 Here, we created several adeno-associated virus (AAV) vectors to deliver genes th

102 itution, Y704A, near the 2-fold interface of adeno-associated virus (AAV) was defective for transcrip

103 We combined the adeno-associated virus (AAV) with the Cre-loxP site-spec

104 retrograde functionality into the capsid of adeno-associated virus (AAV), a vector that has shown pr

105 n mouse are systematically investigated with adeno-associated virus (AAV), an anterograde viral trace

106 ere we present two methods for radiolabeling adeno-associated virus (AAV), one of the most commonly u

107 ct design, RAM can be packaged into a single adeno-associated virus (AAV), providing great versatilit

108 teps in the life cycle of a human virus, the adeno-associated virus (AAV), that causes no known disea

109 Second, we package the library into adeno-associated virus (AAV), thereby allowing delivery

110 Adeno-associated virus (AAV)-Cre-mediated Vgf ablation i

111 Here, we describe a lineage-specific, adeno-associated virus (AAV)-derived endogenous viral el

112 ticospinal neurons specifically by injecting adeno-associated virus (AAV)-expressing Cre-dependent DR

113 Adeno-associated virus (AAV)-hepcidin was injected into

114 We prepared adeno-associated virus (AAV)-IFN-gamma and AAV-IL-4 and

115 Here we report that a system of adeno-associated virus (AAV)-mediated clustered regularl

116 we report a genome editing approach in which adeno-associated virus (AAV)-mediated CRISPR/Cas9 delive

117 on ARVC cardiac manifestations in mice after adeno-associated virus (AAV)-mediated gene delivery of m

118 enerated mice with elevated expression using adeno-associated virus (AAV)-mediated gene delivery.

119 We use adeno-associated virus (AAV)-mediated gene editing to kn

120 While the recent success of adeno-associated virus (AAV)-mediated gene therapy in cl

121 Adeno-associated virus (AAV)-mediated gene therapy is cu

122 We sought to develop an efficient adeno-associated virus (AAV)-mediated RNAi gene therapy

123 plore the therapeutic potential of naked and adeno-associated virus (AAV)-packaged AONs in vitro and

124 ST input, and the right CST was treated with adeno-associated virus (AAV)-Sox11 or AAV-EBFP control,

125 lar dystrophy, dystrophin restoration during adeno-associated virus (AAV)-U7-mediated exon-skipping t

126 irect intrahippocampal administration of the adeno-associated virus (AAV)-vectored anti-phospho-tau a

127 These aptayzmes efficiently regulated adeno-associated virus (AAV)-vectored transgene expressi

128 essed CRY in SCN of Cry-deficient mice using adeno-associated virus (AAV).

129 dystrophic mice more than a decade ago using adeno-associated virus (AAV).

130 he efficient delivery of donor template with adeno-associated virus (AAV).

131 c efficacy of telomerase activation by using adeno-associated virus (AAV)9 gene therapy vectors carry

132 We performed intramuscular injection of an adeno-associated virus (AAV)9 vector expressing GAA (AAV

133 To address this, we developed a novel adeno-associated virus (AAV-GLP-1R) that utilizes short

134 The adeno-associated viruses (AAV) are promising therapeutic

135 Adeno-associated viruses (AAV) are thought to spread thr

136 In the case of recombinant adeno-associated viruses (AAV), proteasome inhibitors ar

137 Here, we discovered that adeno-associated viruses (AAV1 and AAV9) exhibit anterog

138 ta pathology, we investigated the effects of adeno-associated virus (AAV2/1)-mediated expression of I

139 Adeno-associated viruses (AAVs) are attractive gene ther

140 Adeno-associated viruses (AAVs) are commonly used for in

141 Recombinant adeno-associated viruses (AAVs) are promising vectors fo

142 The adeno-associated viruses (AAVs) are promising vectors fo

143 Adeno-associated viruses (AAVs) currently are being deve

144 Adeno-associated viruses (AAVs) display a highly conserv

145 9 presents challenges in packaging it within adeno-associated viruses (AAVs) for clinical application

146 The use of adeno-associated viruses (AAVs) has proven to be an effe

147 sting neutralizing antibodies (NAbs) against adeno-associated viruses (AAVs) pose a major, unresolved

148 Despite the fact that a majority of adeno-associated viruses (AAVs) utilize sialic acid (SIA

149 The adeno-associated viruses (AAVs), which are being develop

150 amine neurons in both the MPP(+)-lesioned or adeno-associated virus alpha-synuclein rat models of Par

151 D1-MSNs versus D2-MSNs using a Cre-inducible adeno-associated virus and Cre lines during cocaine cond

152 urb a specific molecular interaction between adeno-associated virus and its host cell, which can be r

153 Here we designed a hybrid adeno-associated virus and phage (AAVP) vector displayin

154 han HepG2 cells after HBV genome delivery by adeno-associated virus, and stable expression of NTCP in

155 cargo including nucleic acids, polypeptides, adeno-associated viruses, and nanodots.

156 therapy include the emergence of recombinant adeno-associated virus as the vector of choice, capsid e

157 Systemic injection of adeno-associated virus-BAG3(Ile81) (n=9), but not BAG3(M

158 e treatment of a mouse model of OPMD with an adeno-associated virus-based gene therapy combining comp

159 from transgenic mice and from WT mice after adeno-associated virus-based gene transfer of ChR2.

160 We developed an adeno-associated virus-based model exhibiting rapid tau

161 Leading the way has been the use of adeno-associated virus-based strategies for factor IX ge

162 ntramuscular administration of a recombinant adeno-associated virus-based vector (rAAV vector) expres

163 Bovine adenovirus 3, bovine adeno-associated virus, bovine influenza D virus, bovine

164 We introduced adeno-associated virus carrying the gene for either the

165 Using Cre-inducible adeno-associated viruses combined with D1-Cre and D2-Cre

166 We injected recombinant adeno-associated virus containing the CRRY coding sequen

167 we lineage-labeled hepatocytes by injecting adeno-associated virus containing thyroxine-binding glob

168 d deep sequencing results confirmed that our adeno-associated virus-CRISPR/Cas9 strategy was very eff

169 Adeno-associated virus-CYP46A1 infection in R6/2 mice al

170 e, using a combination of electrophysiology, adeno-associated virus-delivered fluorescent proteins, a

171 iabetes and two models of type 2 diabetes by adeno-associated virus delivery of renin (ReninAAV).

172 Here, we show that adeno-associated virus-driven expression of progranulin

173 2 expression in the rostral striatum through adeno-associated virus effectively disrupted or restored

174 BALB/c mice treated with adeno-associated virus encoding the BL6 BAG3 variant (Il

175 We treated mice with either adeno-associated viruses encoding a control (green fluor

176 particle-mediated delivery of Cas9 mRNA with adeno-associated viruses encoding a sgRNA and a repair t

177 We investigated whether exosome-associated adeno-associated virus, (exo-AAV) enabled broad retinal

178 ta signaling in the substantia nigra through adeno-associated virus expressing a constitutively activ

179 With neonatal administration of adeno-associated virus expressing arginase, there is nea

180 g 5-HT system by stereotaxic injection of an adeno-associated virus expressing Cre recombinase (AAV-C

181 of stress-susceptible or mice injected with adeno-associated virus expressing shRNA against Cldn5 ca

182 e that overproduce sclerostin as a result of adeno-associated virus expression from the liver.

183 rate that particular groups of drugs enhance adeno-associated virus gene delivery by unknown mechanis

184 animal models to determine if they increased adeno-associated virus gene delivery.

185 tential for FDA-approved drug enhancement of adeno-associated virus gene therapy, which could result

186 Additionally, adeno-associated virus has demonstrated outstanding pote

187 n of c-Fos using photoreceptor-specific AAV (adeno-associated virus)-hRK (human rhodopsin kinase)-sh_

188 Adeno-associated virus IL-12-treated mice developed hist

189 constructs in mouse rod photoreceptors using adeno-associated virus in Xenopus laevis rod photorecept

190 ng reporter genes into the safe-harbor locus adeno-associated virus integration site 1 in human embry

191 In addition, introduction of 3xMyc-FXR1 via adeno-associated virus into mice leads to the redistribu

192 We used a DREADD, hM3Dq, administered via adeno-associated virus into the LC under a synthetic pro

193 s when the packaging capacity of recombinant adeno-associated virus is limited while tissue-specific

194 Systemic delivery of dCas9/gRNA by adeno-associated virus led to reductions in pathological

195 Moreover, they demonstrated that adeno-associated virus-mediated (AAV-mediated) delivery

196 Furthermore, selective adeno-associated virus-mediated deletion of Esr1 in the

197 nuclein in the adult rat substantia nigra by adeno-associated virus-mediated delivery of a short hair

198 n the R6/2 Huntington's disease mouse model, adeno-associated virus-mediated delivery of CYP46A1 into

199 n CYP46A1 expression in the striatum, via an adeno-associated virus-mediated delivery of selective sh

200 ethylmalonic encephalopathy, liver-targeted adeno-associated virus-mediated ETHE1 gene transfer dram

201 llel, we explored the effects of recombinant adeno-associated virus-mediated expression of Abeta38 an

202 Adeno-associated virus-mediated expression of glucocereb

203 Here we have used anterograde tracing with adeno-associated virus-mediated expression of green fluo

204 llowing high over-expression of WT hAIPL1 by adeno-associated virus-mediated gene delivery, which was

205 u scFvs and tested their efficacy in vivo by adeno-associated virus-mediated gene transfer to the bra

206 ubcellular localizations of each fragment by adeno-associated virus-mediated gene transfer.

207 The effects of adeno-associated virus-mediated Hrd1 knockdown and overe

208 Three approaches were compared: 1) adeno-associated virus-mediated in utero transfer of the

209 Adeno-associated virus-mediated increase in AKT activati

210 Efficient adeno-associated virus-mediated knockdown of ZSCAN21 in

211 ma cells and in mice by peptide injection or adeno-associated virus-mediated overexpression.

212 Adeno-associated virus-mediated PSD-95 KD in the IL, but

213 Adeno-associated virus-mediated restoration of CRALBP ex

214 Adeno-associated virus-mediated Snapin overexpression in

215 We also show that targeted adeno-associated virus-mediated suppression of claudin-5

216 Adeno-associated virus-mediated targeting of RGMa to mou

217 Using a novel adeno-associated virus-mediated technique to label AII a

218 In contrast, transgenic or adeno-associated virus-mediated TNFAIP3 gene delivery in

219 Here we developed an adeno-associated virus-mediated, autochthonous genetic C

220 R-155) in an in vivo model of PD produced by adeno-associated-virus-mediated expression of alpha-syn.

221 A mitochondria-targeted adeno-associated virus (MTS-AAV) containing the mutant h

222 d via stereotactic hippocampal injections of adeno-associated virus particles in APP/PS1 mice, locali

223 n via stereotactic hippocampal injections of adeno-associated virus particles in mutant hAPP Tg mouse

224 ected strategies based on SNTRVAP-displaying adeno-associated virus/phage (AAVP) particles in mice be

225 Adeno-associated virus-progranulin also corrected lysoso

226 The adeno-associated virus-progranulin vector only transduce

227 teral, intranigral injections of recombinant adeno-associated virus pseudotype 2/5 to overexpress wil

228 At day 28, recombinant adeno-associated virus (rAAV) (5 x 10(12) viral particle

229 on of a replication-incompetent, recombinant adeno-associated virus (rAAV) designed to express an ant

230 We administered recombinant adeno-associated virus (rAAV) expressing miS1, an artifi

231 Recombinant adeno-associated virus (rAAV) is an attractive tool for

232 highly efficient CRISPR directed recombinant Adeno-Associated Virus (rAAV) mediated gene targeting ap

233 that gene therapy mediated by a recombinant adeno-associated virus (rAAV) vector expressing human G6

234 n mice receiving high doses of a recombinant adeno-associated virus (rAAV) vector expressing shRNAs (

235 that the non-tumor-bearing (NT), recombinant adeno-associated virus (rAAV) vector-treated GSD-Ia mice

236 lionic or intrathecal injection, recombinant adeno-associated virus (rAAV) vectors can also infect se

237 tional microdystrophin genes and recombinant adeno-associated virus (rAAV) vectors is an attractive s

238 ne therapy in G6pt-/- mice using recombinant adeno-associated virus (rAAV) vectors, directed by eithe

239 ology, we explored the effect of recombinant adeno-associated virus (rAAV)-mediated overexpression of

240 Here we perform recombinant adeno-associated virus (rAAV)-mediated promoterless gene

241 sought to investigate this using recombinant adeno-associated viruses (rAAV)-mediated expression of g

242 Recombinant adeno-associated viruses (rAAVs) are commonly used vehic

243 Adeno-associated virus receptor (AAVR) (also named KIAA0

244 pression of DISC1 in the hippocampus with an adeno-associated virus reduced the levels of BACE1, solu

245 Hepatic arginase 1 gene therapy using adeno-associated virus rescued nearly all these abnormal

246 c brain transgenesis was utilized to deliver adeno-associated virus serotype 1 (AAV1) encoding human

247 Specifically, we labeled adeno-associated virus serotype 10 expressing the coding

248 the inverted terminal repeats (ITRs) in the adeno-associated virus serotype 2 (AAV2) genome signific

249 Assembly-activating protein (AAP) of adeno-associated virus serotype 2 (AAV2) is a nucleolar-

250 rated the virus particle, self-complementary adeno-associated virus serotype 2 carrying the mutated g

251 teral dorsal amygdala Ce-region infusions of adeno-associated virus serotype 2 containing the CRF con

252 control of energy homeostasis, via specific adeno-associated virus serotype 2-mediated overexpressio

253 single intravenous dose of a codon-optimized adeno-associated virus serotype 5 (AAV5) vector encoding

254 rphysiological doses of MIS, using either an adeno-associated virus serotype 9 (AAV9) gene therapy ve

255 acy of gene therapy for NPC1, we constructed adeno-associated virus serotype 9 (AAV9) vectors to deli

256 h SMA1 received a single dose of intravenous adeno-associated virus serotype 9 carrying SMN complemen

257 a potent inducer of premature senescence, by adeno-associated virus serotype 9 gene transfer, resulte

258 CRISPR/Cas9-based cardiac gene editing using adeno-associated virus serotype 9 to deliver a single sh

259 Adeno-associated virus serotype 9 viral vectors carrying

260 In vivo, AAV9 (adeno-associated virus serotype 9)-mediated cardiac over

261 Using intrathecal adeno-associated virus serotype 9-based delivery, the gl

262 ic implications, we found that prior in vivo Adeno-associated virus serotype 9-mediated gene delivery

263 METHODS AND Using an in vivo Adeno-associated virus serotype 9-mediated gene transfer

264 the heart of 7-month-old SJ13 mice using an adeno-associated virus serotype-9 Cre recombinase vector

265 Adeno-associated virus-Sesn2 was delivered to aged heart

266 Knockdown of VTA CTR via adeno-associated virus short hairpin RNA resulted in hyp

267 R induced by intraparenchymal delivery of an adeno-associated virus-short hairpin RNA construct was s

268 We used mice with a mutation in Npas2 and adeno-associated virus-short hairpin RNA mediated knockd

269 Cardiac-specific overexpression of FGF16 via adeno-associated virus subtype 9 (AAV9) in the mutant he

270 g within the VTA, we delivered Cre-inducible adeno-associated virus that drives the expression of flu

271 Here we describe a novel recombinant adeno-associated virus that restricts gene expression to

272 on subretinal or intravitreal injections of adeno-associated virus to deliver the therapeutic gene.

273 c retrograde tracing to label the inputs and adeno-associated virus to trace axonal projections, we i

274 We injected RE with adeno-associated virus to transduce cells with channelrh

275 ntify integrations of murine leukemia virus, adeno-associated virus, Tol2 transposons or Ac/Ds transp

276 rat spinal cord after dorsal root crush and adeno-associated virus transgene expression in dorsal ro

277 ene expression using aerosolized delivery of adeno-associated virus type 1 (AAV1) in a large animal m

278 d with our therapeutic vector, a recombinant adeno-associated virus type 1 (rAAV1) expressing our RNA

279 Vectors based on adeno-associated virus type 2 (AAV2) are powerful tools

280 lind sham-surgery-controlled trial assessing adeno-associated virus type 2 (AAV2)-neurturin injected

281 integration site (IS) analysis of wild-type adeno-associated virus type 2 (wtAAV2) in human dermal f

282 Adeno-associated virus type 2 is known to inhibit replic

283 Moreover, adeno-associated virus type 2-mediated IGF2 overexpressi

284 G of CXCL10(-/-) mice, using the neurotropic adeno-associated virus type 8 (AAV8) vector, boosted the

285 ation of RS1 via retina-specific delivery of adeno-associated virus type 8-RS1 (AAV8-RS1) vector resc

286 ty and tolerability of escalated doses of an adeno-associated virus vector (AAV) expressing a normal

287 cus aureus) and guide RNA constructs into an adeno-associated virus vector and systemically delivered

288 the use of a dominant-negative forkhead boxO adeno-associated virus vector delivered directly to the

289 We transduced NAcore astrocytes with an adeno-associated virus vector expressing hM3D designer r

290 t NOD scid gamma (NSG) mice by the use of an adeno-associated virus vector, followed by engraftment o

291 Intrahippocampal injections of adeno-associated virus vectors containing the astrocyte-

292 we show that expression of these genes from adeno-associated virus vectors in C57BL/6 mice is able t

293 gnaling in a common mouse model of AD, using adeno-associated virus vectors normalized glutamate sign

294 human patients, and gene augmentation using adeno-associated virus vectors robustly sustained the re

295 ts within the packaging limit of recombinant adeno-associated virus vectors that have been shown to b

296 Here we compare the effects of adeno-associated virus vectors with neurotrophin gene in

297 assemblies, similar to the best recombinant adeno-associated virus vectors.

298 In this study, adeno-associated virus was used to deliver the clustered

299 l vectors can package larger transgenes than adeno-associated viruses, yet lentiviral vectors remain

300 liver-specific overexpression of human ZIP8 (adeno-associated virus-ZIP8 [AAV-ZIP8]) resulted in incr