ライフサイエンスコーパス: adenosylmethionine decarboxylase

1 ore potent and more specific inhibitors of S-adenosylmethionine decarboxylase.

2 the decarboxylation reaction catalyzed by S-adenosylmethionine decarboxylase.

3 enzyme alphabeta dimer than with wild-type S-adenosylmethionine decarboxylase.

4 Among the new tumour suppressors are adenosylmethionine decarboxylase 1 (AMD1) and eukaryotic

5 stems from mTORC1-dependent regulation of S-adenosylmethionine decarboxylase 1 (AMD1) stability.

6 ry increase in ornithine decarboxylase and S-adenosylmethionine decarboxylase activities.

7 S proteasome caused substantial losses of S-adenosylmethionine decarboxylase activity despite accumu

8 ues diminished ornithine decarboxylase and S-adenosylmethionine decarboxylase activity.

9 ic genes encoding spermidine biosynthesis: S-adenosylmethionine decarboxylase (AdoMetDC) and spermidi

10 S-adenosylmethionine decarboxylase (AdoMetDC) catalyzes a

11 S-adenosylmethionine decarboxylase (AdoMetDC) catalyzes a

12 Trypanosoma cruzi S-adenosylmethionine decarboxylase (AdoMetDC) catalyzes th

13 orspermine [DENSPM]) at 1 microM; however, S-adenosylmethionine decarboxylase (AdoMetDC) depletion wa

14 The polyamine biosynthetic enzyme, S-adenosylmethionine decarboxylase (ADOMETDC) has been adv

15 with DFMO in combination with SAM486A, an S-adenosylmethionine decarboxylase (AdoMetDC) inhibitor, h

16 S-adenosylmethionine decarboxylase (AdoMetDC) is a critica

17 S-adenosylmethionine decarboxylase (AdoMetDC) is a critica

18 S-Adenosylmethionine decarboxylase (AdoMetDC) is a key enz

19 S-Adenosylmethionine decarboxylase (AdoMetDC) is a key enz

20 S-Adenosylmethionine decarboxylase (AdoMetDC) is a pyruvoy

21 S-Adenosylmethionine decarboxylase (AdoMetDC) is a pyruvoy

22 S-Adenosylmethionine decarboxylase (AdoMetDC) is a pyruvoy

23 S-Adenosylmethionine decarboxylase (AdoMetDC) is a pyruvoy

24 S-Adenosylmethionine decarboxylase (AdoMetDC) is a pyruvoy

25 S-Adenosylmethionine decarboxylase (AdoMetDC) is synthesiz

26 e 5' leader of the mammalian mRNA encoding S-adenosylmethionine decarboxylase (AdoMetDC) serves as a

27 ing and decarboxylation reactions of human S-adenosylmethionine decarboxylase (AdoMetDC), a critical

28 S-adenosylmethionine decarboxylase (AdoMetDC), a key enzym

29 Previously we showed that trypanosomatid S-adenosylmethionine decarboxylase (AdoMetDC), a key enzym

30 Synthesis of S-adenosylmethionine decarboxylase (AdoMetDC), a key regul

31 bitor of the polyamine biosynthetic enzyme S-adenosylmethionine decarboxylase (AdoMetDC), is presentl

32 Instead trypanosomatid S-adenosylmethionine decarboxylase (AdoMetDC), which catal

33 Instead they have two paralogs of the S-adenosylmethionine decarboxylase (AdoMetDC).

34 fusions of polyamine biosynthetic enzymes S-adenosylmethionine decarboxylase (AdoMetDC, speD) and am

35 ort X-ray structures of Trypanosoma brucei S-adenosylmethionine decarboxylase alone and in functional

36 trescine amidohydrolase in archaea, and of S-adenosylmethionine decarboxylase and ornithine decarboxy

37 rmidine from putrescine by the key enzymes S-adenosylmethionine decarboxylase and spermidine synthase

38 imental frameshift frequencies measured in S-adenosylmethionine-decarboxylase and antizyme mutants, a

39 thetic enzymes ornithine decarboxylase and S-adenosylmethionine decarboxylase, and upregulates spermi

40 rboxylase activity despite accumulation of S-adenosylmethionine decarboxylase antigen.

41 in COS-7 cells prevents the degradation of S-adenosylmethionine decarboxylase antigen; however, even

42 cause of a deletion in the gene coding for S-adenosylmethionine decarboxylase are very sensitive to e

43 In contrast, plant S-adenosylmethionine decarboxylases are fully active in th

44 mination accelerates normal degradation of S-adenosylmethionine decarboxylase, as the rate of degrada

45 S-Adenosylmethionine decarboxylase belongs to a small clas

46 ess that is accelerated by inactivation of S-adenosylmethionine decarboxylase by substrate-mediated t

47 We have determined the structures of S-adenosylmethionine decarboxylase complexed with the comp

48 deletion-insertion in the gene coding for S-adenosylmethionine decarboxylase (Deltaspe2) have an abs

49 hyltetrahydrofolate:Hcy methyltransferase, S-adenosylmethionine decarboxylase, DNA methyltransferase

50 S-Adenosylmethionine decarboxylase from Escherichia coli i

51 We have determined the structure of the S-adenosylmethionine decarboxylase from potato, Solanum tu

52 rated by isolation of His-tagged AdoMetDC (S-adenosylmethionine decarboxylase) from COS-7 cells co-tr

53 We expressed a yeast S-adenosylmethionine decarboxylase gene (ySAMdc; Spe2) fus

54 S-Adenosylmethionine decarboxylase has a four-layer alphab

55 S-Adenosylmethionine decarboxylase has been implicated in

56 activities of ornithine decarboxylase and S-adenosylmethionine decarboxylase in a similar fashion.

57 the constitutively high activity of plant S-adenosylmethionine decarboxylases in the absence of putr

58 in the optimal structural requirements for S-adenosylmethionine decarboxylase inhibition and potentia

59 provide a framework for interpretation of S-adenosylmethionine decarboxylase inhibition data and sug

60 bitor alpha-difluoromethylornithine or the S-adenosylmethionine decarboxylase inhibitor MDL-73811 low

61 zone (MGBG), a polyamine analog and potent S-adenosylmethionine decarboxylase inhibitor, decreases HI

62 reading frame (uORF) in the mRNA encoding S-adenosylmethionine decarboxylase is a cis-acting element

63 reading frame (uORF) in the mRNA encoding S-adenosylmethionine decarboxylase is a polyamine-responsi

64 S-Adenosylmethionine decarboxylase is a pyruvate-dependent

65 In mammals, S-adenosylmethionine decarboxylase is active as a dimer in

66 Ubiquitination of S-adenosylmethionine decarboxylase is demonstrated by isol

67 Human S-adenosylmethionine decarboxylase is synthesized as a pro

68 Here we demonstrate that S-adenosylmethionine decarboxylase is ubiquitinated and de

69 anosomatid spermidine biosynthetic enzyme, S-adenosylmethionine decarboxylase, is regulated by hetero

70 The availability of the recombinant H243A S-adenosylmethionine decarboxylase proenzyme provides a us

71 deoxyadenosine (MDL73811), an inhibitor of S-adenosylmethionine decarboxylase, resulted in increased

72 In the present study, S-adenosylmethionine decarboxylase (SAMDC), a key gene inv

73 thesis, ornithine decarboxylase (ODC), and S-adenosylmethionine decarboxylase (SAMdc), were measured

74 ase), speC (ornithine decarboxylase), spe D (adenosylmethionine decarboxylase), speE (spermidine synt

75 n levels of ornithine decarboxylase and of S-adenosylmethionine decarboxylase, two essential enzymes

76 ect evidence of peptide synthesis from the S-adenosylmethionine decarboxylase uORF using an in vitro

77 The short-lived enzyme S-adenosylmethionine decarboxylase uses a covalently bound

78 The catalytic mechanism of human S-adenosylmethionine decarboxylase was investigated via mu

79 Both wild-type and C82A mutant S-adenosylmethionine decarboxylases were inactivated by su