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1 treatment, the nonhydrolyzable ATP analogue, adenyl 5'-(yl iminodiphosphate), does not enhance ADP tr
3 of the nonhydrolyzable ATP analogue AMP-PNP (adenyl-5'-yl imidophosphate), the ectonucleotidase inhib
4 experimental data for the 3-atom-linked bis-adenyl and bis-naphthyl compounds are consistent with th
5 do-photoactive analogues of ATP, ADP, and 5'-adenyl-beta,gamma-imidodiphosphate (AMP-PNP) with the tw
6 mations are sterically accessible to the bis-adenyl compound than to the bis-naphthyl compound becaus
8 atic interactions, why the 3-atom-linked bis-adenyl compounds should stack more than the bis-naphthyl
10 gonist isoproterenol (by 42%), 10 muM of the adenyl cyclase activator forskolin (by 32%), and 500 muM
13 se to catecholamine signals, when it reduced adenyl cyclase activity by upregulating the expression o
16 ast, forskolin and NaF, direct activators of adenyl cyclase and Gs, respectively, elicited comparable
20 -evoked NO release was also abolished by the adenyl cyclase inhibitor 2',5'-dideoxyadenosine, while d
26 n and Paul Greengard of a dopamine-sensitive adenyl cyclase, accordingly, was a giant step forward.
27 c stimulation, it produces reduced levels of adenyl cyclase, and hence, attenuates the beta-adrenergi
28 well-defined site is clearly identified with adenyl cyclase, beta/gamma and regulator of G-protein si
29 rylation by forskolin, a potent activator of adenyl cyclase, decreases HDAC8's enzymatic activity.
30 ent studies show that edema factor, a potent adenyl cyclase, has the ability to make a substantial co
32 ance, including G-protein-coupled receptors, adenyl cyclase, protein kinase A and cAMP response eleme
33 h encode the Ras GDP/GTP exchange factor and adenyl cyclase, respectively, and MDS3, which encodes a
38 ocyanobilin via their cGMP phosphodiesterase/adenyl cyclase/FhlA (GAF) domains and then assume the ph
41 g of the Te-PixJ GAF (cGMP phosphodiesterase/adenyl cyclase/FhlA) domain assembled with phycocyanobil
42 (Per-ARNT-Sim), GAF (cGMP phosphodiesterase/adenyl cyclase/FhlA), and PHY (phytochrome) domains to a
47 based upon NMR data showing stacking for two adenyl groups joined by a 3-atom linker but not for two
48 roups tend to lie further apart than stacked adenyl groups, based upon both quantum calculations and
49 e the linker is attached to the sides of the adenyl groups, but to the ends of the naphthyl groups.
50 ne-5'-O-(3-thiotriphosphate) (ATPgammaS) and adenyl-imidodiphosphate, each stabilized the primer reco
52 the minor conformation, but suggest that the adenyl moiety in the modified nucleoti111S,R, S,RA6 adop
56 sphates over nucleotide diphosphates and for adenyl nucleotides over the corresponding guanyl ones wa
60 of ATP release and the relative abundance of adenyl purines and, hence, to define their biological fu
62 considered to be depurination of a specific adenyl residue of ribosomal RNA, resulting in inhibition
65 N(6)-adenyl)styrene oxide and (S)-beta-(N(6)-adenyl)styrene oxide adducts at position X(6) in d(CGGAC
67 Conformational studies of R- and S-alpha-(N6-adenyl)styrene oxide adducts mismatched with deoxycytosi
69 confirmed the presence of the aminoglycoside adenyl transferase (aadA) gene, conferring St Spc resist
70 tRNA(Trp) and catalyzes the formation of 5' adenyl-Trp and tRNA(Trp), with approximately five times
71 ersion that abolishes secretion, uridyl 9 to adenyl (U9A), is a synonymous codon 3 mutation that reta
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