1 ty of the mutant form of Gsalpha to regulate adenylylcyclase.

2 r content of cAMP generated by activation of adenylylcyclase (AC) through the beta-adrenergic recepto

3 r content of cAMP generated by activation of adenylylcyclase (AC; EC 4.6.1.1) is a key determinant of

4 evels of G protein alpha subunits regulating adenylylcyclase activity (Gs alpha-both 45- and 52-kDa f

5  (1) beta 1-mRNA and receptor expression and adenylylcyclase activity and (2) beta 1-mRNA and recepto

6 gnificant attenuation of SKF81297-stimulated adenylylcyclase activity in D(1) dopamine receptor-expre

7 s showed no reduction of SKF81297-stimulated adenylylcyclase activity in D(5) dopamine receptor-expre

8 eceptors, particularly at the mRNA level, or adenylylcyclase activity in isolated cardiac myocytes ex

9 e of the gamma7 subunit in the regulation of adenylylcyclase activity in response to isoproterenol.

10 A and receptor expression but does not alter adenylylcyclase activity stimulated at either the recept

11                                              Adenylylcyclase activity stimulated by isoproterenol, so

12 enol-, but not prostaglandin E1-, stimulated adenylylcyclase activity.

13 ne receptor, G protein gamma(7) subunit, and adenylylcyclase are selectively expressed in the striatu

14 4)/Gsalpha produced a chimera that activated adenylylcyclase but abolished progression to primitive e

15 signaling of beta2-adrenergic receptors from adenylylcyclase coupling to the mitogen-activated protei

16  beta 1-mRNA and receptor downregulation and adenylylcyclase desensitization in response to isoproter

17  beta 1-mRNA and receptor downregulation and adenylylcyclase desensitization induced by prolonged nor

18  of distinct betagamma subunits to stimulate adenylylcyclase in HEK 293 cells.

19 or downregulation and desensitization of the adenylylcyclase response.

20 recognized that the beta-adrenergic receptor-adenylylcyclase system is altered during myocardial isch