ライフサイエンスコーパス: adenylyltransferase

1 o covalent modification (adenylylation by GS adenylyltransferase).

2 s a nicotinic acid mononucleotide-preferring adenylyltransferase.

3 ors is carried out by MccB THIF-type NAD/FAD adenylyltransferases.

4 es of Fic proteins with those of other known adenylyltransferases.

5 rase (NAMPT) and nicotinamide mononucleotide adenylyltransferase 1 (NMNAT-1) constitute a nuclear NAD

6 The nicotinamide nucleotide adenylyltransferase 1 (NMNAT1) enzyme is essential for r

7 verexpression of nicotinamide mononucleotide adenylyltransferase 1 (Nmnat1) or exogenous application

8 ding sequence of nicotinamide mononucleotide adenylyltransferase 1 (Nmnat1), which alone is sufficien

9 Nicotinamide mononucleotide (NMN) adenylyltransferase 2 (Nmnat2) catalyzes the synthesis o

10 thesizing enzyme nicotinamide mononucleotide adenylyltransferase 2 (NMNAT2) is a critical survival fa

11 evels of NMNAT2 (nicotinamide mononucleotide adenylyltransferase 2), a recently identified survival f

12 clear isoform of nicotinamide mononucleotide adenylyltransferase, a rate-limiting enzyme in nicotinam

13 by LigB, thus confirming that the ligase and adenylyltransferase activities are intrinsic to the LigB

14 bose at position -3 markedly stimulates both adenylyltransferase activity and stable binding.

15 igase is thermophilic in vitro, with optimal adenylyltransferase activity at 90 degrees C and nick-jo

16 untingtin yeast interacting protein E), with adenylyltransferase activity but unknown physiological t

17 rate that the PfhB2 Fic domains also possess adenylyltransferase activity that targets the switch 1 t

18 verexpression of GS in glnE mutants (lacking adenylyltransferase activity) also causes poor growth.

19 the primer is absolutely required for VP55's adenylyltransferase activity, but not for stable VP55-RN

20 ereas LigC and LigD, which have ATP-specific adenylyltransferase activity, display weak nick joining

21 her yeast NMNATs, Pof1 exhibits NMN-specific adenylyltransferase activity.

22 lylation (inactivation) by a bifunctional GS adenylyltransferase/adenylyl-removing enzyme (ATase).

23 ggesting that GlnK-UMP is required to signal adenylyltransferase/adenylyl-removing enzyme-mediated de

24 pyrophosphorylase (AGP; glucose-1-phosphate adenylyltransferase; ADP: alpha-D-glucose-1-phosphate ad

25 ucose pyrophosphorylase (glucose-1-phosphate adenylyltransferase; ADP:alpha-D-glucose-1-phosphate ade

26 (ybeN) coding for nicotinate mononucleotide adenylyltransferase, an NAD(P) biosynthetic enzyme, has

27 Adenylyltransferase and DNA ligation activities are pres

28 ses characterized to date have ATP-dependent adenylyltransferase and nick-joining activities.

29 ridylyltransferase/uridylyl-removing enzyme, adenylyltransferase, and the kinase/phosphatase nitrogen

30 , and the C-terminal NT domain contained the adenylyltransferase (AT) active site.

31 In vivo, adenylyltransferase (AT) activity is critical for growth

32 The adenylyltransferase (AT) activity of ATase is activated

33 toglutarate and ADP on PII activation of the adenylyltransferase (AT) activity of ATase.

34 The adenylyltransferase (AT) reaction is activated by glutam

35 enzyme nicotinic acid mononucleotide (NaMN) adenylyltransferase (AT), is essential for the synthesis

36 es of the PII receptors glutamine synthetase adenylyltransferase (ATase) and the kinase/phosphatase n

37 ntrol the activities of glutamine synthetase adenylyltransferase (ATase) but did not affect the abili

38 Glutamine synthetase adenylyltransferase (ATase) regulates the activity of gl

39 II (NRII) and the glutamine synthetase (GS) adenylyltransferase (ATase), and is subject to reversibl

40 ate in a reconstituted system containing GS, adenylyltransferase (ATase), the PII signal transduction

41 Both GlnK and PII also acted through adenylyltransferase (ATase, the glnE product) to regulat

42 A new family of adenylyltransferases, defined by the presence of a Fic d

43 recombinant bifunctional phosphopantetheine adenylyltransferase/dephospho-CoA kinase was kinetically

44 We identify five amino acids in the adenylyltransferase domain (Lys114, Glu266, Gly267, Lys2

45 k depends on contacts to both the N-terminal adenylyltransferase domain and its signature C-terminal

46 no acid polypeptide composed of a C-terminal adenylyltransferase domain fused to a distinctive 126 am

47 stinctive structure composed of a C-terminal adenylyltransferase domain linked to an N-terminal modul

48 Trl1 consists of an N-terminal adenylyltransferase domain that resembles T4 RNA ligase

49 a sudden (NH4)+ upshift, strains lacking GS adenylyltransferase drain their glutamate pool into glut

50 eine decarboxylase (EC ), phosphopantetheine adenylyltransferase (EC ), and dephospho-CoA kinase (EC

51 transferase; ADP:alpha-D-glucose-1-phosphate adenylyltransferase, EC 2.7.7.27) catalyzes a key regula

52 ransferase; ADP: alpha-D-glucose-1-phosphate adenylyltransferase, EC 2.7.7.27), a key starch biosynth

53 Bacterial nicotinate mononucleotide adenylyltransferase encoded by the essential gene nadD p

54 tabolite of WldS/nicotinamide mononucleotide adenylyltransferase enzymatic activity, is sufficient an

55 n by both NMNAT (nicotinamide mononucleotide adenylyltransferase) expression and loss of wallenda/DLK

56 et another member of the pyridine nucleotide adenylyltransferase family.

57 Flavin mononucleotide adenylyltransferase (FMNAT) catalyzes the formation of t

58 s the RFK activity, while the N-terminal FMN-adenylyltransferase (FMNAT) exhibits the FMNAT activity.

59 he core dinucleotide-binding fold with other adenylyltransferases from bacteria to human despite a li

60 These enzymes, NaMN adenylyltransferase (gene nadD) and NAD synthetase (gene

61 or is controlled post-translationally by the adenylyltransferase (GlnE) as in enteric bacteria.

62 utagenic exploration of the PPi motif in any adenylyltransferase is that the residues of the motif pa

63 Nicotinate mononucleotide adenylyltransferase NadD is an essential enzyme in the b

64 nstream enzymes of NAD synthesis, nicotinate adenylyltransferase (NadD family) and NAD synthetase (Na

65 of NAD biogenesis, nicotinate mononucleotide adenylyltransferase (NadD) and NAD synthetase (NadE), ar

66 Bacterial nicotinic acid mononucleotide adenylyltransferase (NaMNAT; EC 2.7.7.18) encoded by the

67 on is catalyzed by nicotinate mononucleotide adenylyltransferase (NMAT), which is essential for bacte

68 The central domain has a weak adenylyltransferase (NMN-AT; EC 2.7.7.1) activity that c

69 f nicotinamide/nicotinic acid mononucleotide adenylyltransferase (NMNAT) act as a powerful suppressor

70 of NAD synthase nicotinamide mononucleotide adenylyltransferase (NMNAT) against activity-induced neu

71 , (ii) a central nicotinamide mononucleotide adenylyltransferase (NMNAT) domain, and (iii) a C-termin

72 synthesis enzyme nicotinamide mononucleotide adenylyltransferase (NMNAT) have uncovered a novel neuro

73 Nicotinamide mononucleotide adenylyltransferase (NMNAT) is a conserved enzyme in the

74 inamide/nicotinate mononucleotide (NMN/ NaMN)adenylyltransferase (NMNAT) is an indispensable enzyme i

75 verexpression of nicotinamide mononucleotide adenylyltransferase (Nmnat), a component of the slow Wal

76 d nicotinamide/nicotinic acid mononucleotide adenylyltransferase (Nmnat), and we examined its effects

77 it is a putative nicotinamide mononucleotide adenylyltransferase (NMNAT).

78 on of Wld(S) and nicotinamide mononucleotide adenylyltransferase (Nmnat).

79 cal to the human nicotinamide mononucleotide adenylyltransferase (NMNAT).

80 synthesis enzyme nicotinamide mononucleotide adenylyltransferase (NMNAT1) is frequently deleted in hu

81 ynthetic enzyme, nicotinamide mononucleotide adenylyltransferase (Nmnat1).

82 cipate; we discuss scenarios in which the 5'-adenylyltransferase of RtcA might play a role.

83 The second step is performed by NMN adenylyltransferase of the NadM family.

84 ferring enzymes such as glutamine synthetase adenylyltransferase or kanamycin nucleotidyltransferase,

85 pathways, including three distantly related adenylyltransferases (orthologs of the E. coli genes nad

86 Pyridine nucleotide adenylyltransferase (PNAT) is an indispensable central e

87 Phosphopantetheine adenylyltransferase (PPAT) catalyzes the penultimate ste

88 Phosphopantetheine adenylyltransferase (PPAT) catalyzes the penultimate ste

89 Phosphopantetheine adenylyltransferase (PPAT) from Escherichia coli is an e

90 Phosphopantetheine adenylyltransferase (PPAT) is an essential enzyme in bac

91 Phosphopantetheine adenylyltransferase (PPAT) is an essential enzyme in the

92 Phosphopantetheine adenylyltransferase (PPAT) regulates the key penultimate

93 Each phosphopantetheine adenylyltransferase (PPAT) subunit displays a dinucleoti

94 nicotinamide mononucleotide (NMN)-preferring adenylyltransferase (slr0787 gene).

95 Enzyme assays showed that one of the adenylyltransferases specifically recognizes aspartic ac

96 , the S. aureus NaMNAT represents a distinct adenylyltransferase subfamily identifiable in part by co

97 termined that Delta97nsP4 possesses terminal adenylyltransferase (TATase) activity, as it specificall

98 in putative sulfate permease and not sulfate adenylyltransferase transcripts, suggesting a role for f

99 nd compare its activity with other known Fic adenylyltransferases, VopS (Vibrio outer protein S) from

100 sed biosynthetic pathway, two genes encoding adenylyltransferases were overexpressed and the resultin

101 Unlike other bacterial adenylyltransferases, where a partially conserved histid