ライフサイエンスコーパス: administer

1 e, given over 10 minutes, should be promptly administered.

2 tensified or allergy immunotherapy should be administered.

3 endemic and ivermectin cannot be safely mass administered.

4 hrelin/placebo infusion (16.9 ng/kg/min) was administered.

5 VI; 25 mug), or the combination of FF/VI was administered.

6 ease diagnosis anywhere that patient care is administered.

7 ming the findings of the animal studies when administering 1 to healthy human volunteers, a phase I c

8 bust model of metabolic syndrome (MeS), were administered 1000mg/kg of flavanol enriched grape seed p

9 und that subcutaneous (SC) OA-NO2 injections administered 18 h prior to sensitization and elicitation

10 included: IPV shortages (20%), hesitancy to administer 2 injectable vaccines (28%), lack of knowledg

11 s survival in both male and female mice when administered 24 hours after radiation and shows MyD88-de

12 ry records (7DDRs) or up to 4 automated self-administered 24-hour recalls (ASA24s) over a 1-year peri

13 ng of ANS and mortality, a simulation of ANS administered 3 hours before delivery to infants who did

14 tely blocked ethanol-induced NREM sleep when administered 30 min prior to (but not after) ethanol inj

15 Rats self-administered 60% high fat or chow 45 mg pellets and were

16 e metastatic breast cancer were enrolled and administered (89)Zr-pertuzumab.

17 These findings suggest that the campaign to administer a third dose of MMR vaccine improved mumps ou

18 In a mouse model of IP, we administered a single intravenous dose of the adeno-asso

19 We examined this by administering a probabilistic reward learning task to yo

20 These effects are reversed by administering a small FOXO1-derived phospho-mimicking pe

21 This technique administers a very high radiation dose and effectively c

22 Ranibizumab 0.5 mg administered according to a T&E regimen was statisticall

23 The administered activities were high, and long-term toxicit

24 tumor to bone marrow absorbed dose per unit administered activity of (131)I, after THW and rhTSH, wa

25 The absorbed dose per unit administered activity to the bone marrow was 0.13, 0.086

26 uman monoclonal antibodies were systemically administered after acute SCI, and were detected in serum

27 of extended adjuvant therapy with neratinib, administered after chemotherapy and trastuzumab, signifi

28 C-SERS to detect dobutamine, a drug commonly administered after heart surgery.

29 Isoflurane or sevoflurane administered after the ischemic insult reduced brain inf

30 ectiveness of MDPV, methylone, and caffeine, administered alone and as binary mixtures (n=12 per mixt

31 y of long-acting pasireotide and everolimus, administered alone or in combination, in patients with a

32 ltrexone (50 mg) or placebo for 16 weeks and administered an fMRI alcohol cue reactivity task at base

33 Separately, colons of mice administered an mRNA encoding firefly luciferase with ul

34 Dual-task gait testing is easy to administer and may be used by clinicians to decide furth

35 Treg expansion approaches, how many Tregs to administer and when, and how to care for patients after

36 ns (180 questions per examination form) were administered and 3461 questions (96.1%) were mapped into

37 ndividual data on herpes zoster vaccinations administered and consultations for herpes zoster and pos

38 ideation significantly on both the clinician-administered and self-report outcome measures.

39 administrations or the total amount of GBCA administered and signal change for any ROI.

40 lactate, bundle compliance, amount of fluid administered, and hemodynamic goal achievements were not

41 infection it is initiated or how long it is administered, and therapy interruption almost invariably

42 ment NRS to detect gentamicin, a commonly IV-administered antibiotic and EC-SERS to detect dobutamine

43 noclonal antibodies fused to Env gp140, were administered as a boost with poly-ICLC adjuvant either a

44 multiple-ascending-dose trial of inclisiran administered as a subcutaneous injection in patients at

45 ssessed using a food frequency questionnaire administered as part of a population-based case-control

46 Durvalumab was administered at 10 mg/kg every 2 weeks or 1,500 mg every

47 nd brain, respectively, when compound 23 was administered at 50 mg/kg via single dose ip.

48 Adjuvant chemotherapy administered at different time points after surgery.

49 Although MDMA administered at either phase did not affect overall memo

50 , is without significant central action when administered at moderate doses, but fairly simple struct

51 responses to dry eye symptom questionnaires administered at the initial visit and 1 year later, as w

52 was observed when BNN27 (10 mg/kg i.p.) was administered at the onset of diabetes, every other day f

53 or intratracheal plain sildenafil did, when administered at the same dose.

54 Oral glucose tolerance tests were administered at the same time and light phase during the

55 c signaling, MMTV-ErbB2 transgenic mice were administered AZD4547 (2-6 mg/kg/day) for 10 weeks during

56 an ongoing phase Ib clinical trial (TATTON) administering AZD9291 and selumetinib to EGFR-mutant lun

57 Chemotherapy administered before adoptive T-cell transfer has been sh

58 pitulated the protective effects of CpG when administered before allergen sensitization or challenge.

59 roved outcomes when adjuvant chemotherapy is administered before, rather than concurrently with, radi

60 rates of BPAR were 2-fold higher in patients administered belatacept every 8 weeks vs every 4 weeks.

61 month during 4 years of follow-up from self-administered, biennial questionnaires administered in 20

62 e Quick Inventory of Depressive Symptoms was administered bimonthly, and rates of clinically signific

63 animal model of multiple sclerosis (MS), we administered blocking antibody to CLEC12A that significa

64 ilar at day 28 between the microneedle patch administered by a health-care worker versus the intramus

65 antiviral activity and a long half-life when administered by injection that prevented simian-HIV infe

66 Administered by itself, KWAR23 is inert, but given in co

67 1 both caused neuroinflammation in vivo when administered by stereotaxic injection into mouse spinal

68 ysicians to prescribe medications to be self-administered by terminally ill patients to hasten their

69 ns and Whites receiving surgery at hospitals administered by the Department of Defense.

70 The National Vital Statistics System (NVSS), administered by the federal government and based on stat

71 An intravenously (IV) administered calcimimetic could improve adherence and re

72 the present study, the role of systemically-administered CAR-DCN in AAA progression and rupture was

73 care Part D beneficiaries who receive orally administered chemotherapy.

74 nity, has yielded safe and protective orally administered cholera vaccines that are now globally stoc

75 ical practice based on available evidence in administering CNS-directed prophylaxis.

76 Rats were trained to self-administer cocaine (n = 96) or were used as yoked-saline

77 to an enhancement in the motivation to self-administer cocaine as measured using a progressive ratio

78 Rats were trained to self-administer cocaine, during which time each active lever

79 einstatement of cocaine seeking in mice self-administering cocaine.

80 n 100 mg/m(2) given once every 3 weeks, both administered concurrently with curative intent radiother

81 Pomalidomide was administered continuously and dexamethasone was given on

82 sting that lowering the total amount of drug administered could lower toxicities while not compromisi

83 igated the atheroprotective action of orally administered CrP in type 1 diabetic apolipoprotein E-def

84 Drug-naive rats did not self-administer CTDP-32476.

85 red epirubicin and 600 mg/m(2) intravenously administered cyclophosphamide on day 1 every 3 weeks, fo

86 We tested this hypothesis by administering cyclophosphamide and doxorubicin (Cyclo/Do

87 at this dose plus five [11%] of 45 initially administered D who crossed over to D + T).

88 CB0313.1 was administered daily by oral gavage to leptin (db/db) mice

89 CBD or vehicle was administered daily throughout the alcohol feeding study.

90 Adiponectin knock-out mice were orally administered dextran sulfate sodium for 7 days and were

91 ve and Negative Syndrome Scale and Clinician-Administered Dissociative Symptoms Scale.

92 a surveillance period of 2 h after the last administered dose, and a prolonged surveillance after di

93 Conclusion Administered doses of (99m)Tc-MAG3 in the range of 300-3

94 cessary radiation exposure can be avoided by administering doses in the range of 37-185 MBq as recomm

95 ne of three unblinded PrEP regimens for self-administered dosing over 24 weeks: daily; time-driven (t

96 h transmembrane proteins mediating efflux of administered drugs, thereby keeping their intracellular

97 titude of resistance mechanisms necessitates administering drugs in combination, significantly compli

98 rmacologic PKC-theta inhibitor (Compound 20) administered during allergen challenge reduced ILC2 numb

99 butyrate (HB) or placebo (PLA) were rectally administered during fasting and postprandial conditions

100 y benefit from supportive care interventions administered during the second year after diagnosis.

101 The multivariable VE estimate for Tdap administered during the third trimester of pregnancy was

102 subjects prior to giving them access to self-administer each drug.

103 One month later, mice administered Edn2 exhibited breakdown of the BRB with in

104 77 suppressed DNFB-induced inflammation when administered either before or after the DNFB challenge.

105 The next day, they were administered either intranasal insulin (60 IU) or placeb

106 and tolerability of multiple doses of VRC01 administered either subcutaneously or by intravenous (IV

107 ect design, healthy adult men (n = 121) were administered either T or placebo, and subsequently engag

108 xel (four cycles of 90 mg/m(2) intravenously administered epirubicin and 600 mg/m(2) intravenously ad

109 Pharmacokinetic data suggest that 800 mg administered every 12 weeks is a suboptimal regimen; alt

110 375 mg per square meter of body-surface area administered every 2 months for 3 years after transplant

111 midy, the LS4, predicts pediatric falls when administered every day and night shift, but identifies m

112 We examined whether administering extracts of MSCs (MSC-Ex) instead of MSCs

113 ohistochemical data show that a systemically administered fluorescent GLP-1R agonist accesses the LDT

114 Enterally administered fluorophores can identify intestinal injury

115 In contrast, stress administered following a delay led to heightened arousal

116 r Americans and derived from a 137-item self-administered food-frequency questionnaire.

117 ycle) or with 1660 mg/m(2) oral capecitabine administered for 21 days followed by 7 days' rest (one c

118 Chemotherapy was administered for at least 24 weeks followed by antibody

119 travenous immunoglobulin (IVIG) is sometimes administered for presumptive toxic shock syndrome (TSS),

120 To undertake safety testing of oral X-82 administered for the treatment of neovascular AMD.

121 Study drugs were administered for up to 12 months.

122 Autologous thrombus was administered from below the filter in seven swine from 0

123 treated ghrelin receptor-null mice that were administered GcgR monoclonal antibody.

124 in humans, we evaluated whether peripherally administered GLP-1R agonists access the LDTg to affect f

125 Administered hCG reduces risk of carcinogen-induced brea

126 PfSPZ Vaccine at a dose of 9.0 x 10(5) PfSPZ administered i.v. three times at 8-wk intervals to 15 ma

127 We administered IdeS to 25 highly HLA-sensitized patients (

128 y T cells (2 x 106/mouse) were intravenously administered immediately after delayed tPA treatment in

129 e gastrointestinal drug absorption of orally administered immunosuppressive medications posttransplan

130 m self-administered, biennial questionnaires administered in 2010 and 2012.

131 commonly used chemotherapeutic agent and was administered in 21 of 63 patients (33%).

132 Blinatumomab was administered in 28-day cycles by continuous intravenous

133 Adjunctive phenobarbital was administered in 5 of 33 infants (15%) in the buprenorphi

134 erm survivors, imatinib was the sole therapy administered in 69 (48.6%), with additional systemic age

135 Laser photocoagulation was administered in 75 eyes (62.0%), out of which 29 (38.1%)

136 Steroids were administered in 77.7% of patients.

137 f saline and isoproterenol (1 or 2 mug) were administered in a blinded manner while participants cont

138 treatments were identical in appearance and administered in a masked manner; patients, investigators

139 When both enzymes were administered in a prophylactic or therapeutic fashion, a

140 ansferred to other organs.VA supplementation administered in a single high dose during the first mont

141 y of tumors, these small molecules are often administered in combination to prevent emergence of resi

142 rentuximab vedotin (BV) and nivolumab (Nivo) administered in combination were evaluated as initial sa

143 7 inhibitors can only produce analgesia when administered in combination with an opioid.

144 ), a member of the IL-1 family of cytokines, administered in combination with SP (1 microM), markedly

145 let-derived growth factor (PDGF) antagonist, administered in combination with the anti-vascular endot

146 ity of bloodstream MRSA infection, even when administered in conjunction with vancomycin prophylaxis.

147 Study drugs were administered in identical capsules, and interventions, a

148 e low homing efficiency of MSCs systemically administered in inflammatory bowel diseases (IBD).

149 um, normal saline, and gadoterate meglumine, administered in random order in a single session.

150 ily, 7-day course of investigational product administered in sodium bicarbonate 15 minutes after each

151 In addition, garcinol administered in the absence of reconsolidation or at a 6

152 limited evidence that a short course of IVIG administered in the MCI stage of AD reduces brain atroph

153 ry signaling alters drug-taking behavior, we administered intracranial injections of plasmid DNA enco

154 PIV5-RSV F was equally protective when administered intranasally or subcutaneously.

155 Rapamycin was administered intraperitoneally daily for 14 days at 0.5

156 established in C57BL/6 mice, and MSC-Ex was administered intraperitoneally.

157 anlizumab (5.0 mg per kilogram), or placebo, administered intravenously 14 times over a period of 52

158 s significantly improved renal function when administered intravenously 24 and 48 hours after renal i

159 g/m(2) gemcitabine to the paclitaxel cycles, administered intravenously as a 0.5 h infusion on days 1

160 When administered intravenously, PpZEV NPs rapidly accumulate

161 of the use of iodinated contrast media (ICM) administered intravenously.

162 Human MSCs, grown chronically at 5% O2, were administered intravenously.

163 ia vaccine in a mouse model of malaria by co-administering it with vaccine adjuvants.

164 susceptibility to IAV infection in vivo, we administered KGF 120, 48, 24, and 0 h before intrapulmon

165 We administered lentiviral transcription factor activated l

166 mune suppression to more frequently and i.v. administered licensed therapies.

167 cy) and Six-Item Screener (SIS) assessments, administered longitudinally during follow-up.

168 Rodents chronically administered loop diuretics develop DR due to compensato

169 this is the first report showing that orally administered mastic oil induces tumor-suppressing effect

170 ample of comparison participants (N=18) were administered measures of cognitive function and question

171 staff (35 nurses, 6 carers) were observed to administer medications to 823 residents during 90 medica

172 t researcher directly observed solid, orally administered medications in tablet or capsule form at te

173 Nurses and carers administering medications.

174 strate a unique approach to solubilizing and administering membrane-bound proteins for future vaccine

175 Adult male/female rhesus monkeys self-administered methamphetamine (0.03 mg/kg/injection, i.v.

176 AT3(+) CD11c(+) cells was higher in Per a 10-administered mice and was reduced upon PAR-2 blockage.

177 y of the ability of latiglutenase, an orally administered mixture of 2 recombinant gluten-targeting p

178 such studies is the ability of sequentially administered, modified immunogens (designed to bind prog

179 Drugs were administered monthly in each of the groups for a total d

180 Because few intravenously administered MSCs engraft in the myocardium, studies hav

181 Intravenously administered MSCs for acute myocardial infarction attenu

182 nfirm the significance of MT, we exogenously administered MT-I after cerebral I/RI and found that it

183 hanges in EEG patterns during a continuously administered neurofeedback of P4 alpha activity.

184 ctions, number of reactions where NMBAs were administered, number of reactions where serum IgE antibo

185 can be produced in large quantities, easily administered off-the-shelf early after an acute myocardi

186 In addition, both drugs have to be administered on a daily basis due to their short half-li

187 o 4 cycles of combination treatment, with BV administered on day 1 and Nivo on day 8 of the first cyc

188 FGF2 administered on the day after birth facilitated extincti

189 les of either 1000 mg/m(2) gemcitabine alone administered once a week for three of every 4 weeks (one

190 to-treat analysis indicating that exenatide, administered once weekly, was noninferior to placebo wit

191 s calculated as the number of observed doses administered (or omitted) in error according to medicati

192 PT2385 was administered orally at twice-per-day doses of 100 to 1,8

193 Patients and Methods MK-8242 was administered orally twice a day on days 1 to 7 in 21-day

194 ratio, to four regimens: 5 mg of tofacitinib administered orally twice daily (132 patients); 10 mg of

195 The effects of systemic or centrally administered orexin receptor (OXR) antagonists on measur

196 ning antivirals might be more effective than administering oseltamivir alone in the treatment of infl

197 quivocably demonstrate that the peripherally administered OT is entering the CSF.

198 n the OT and opioid systems and suggest that administering OT under opioid antagonism may boost the t

199 care in B-cell non-Hodgkin lymphoma, and is administered over 1.5-6 h.

200 ossover design to determine how intranasally administered oxytocin and vasopressin modulated neural a

201 herichia coli can be manipulated in vitro by administering pairs of antibiotics and switching between

202 We trained rats to self-administer palatable food pellets (6 d, 6 h/d) and metha

203 -like state also developed in guinea pigs IV administered PEO+.

204 creased the number of alcohol infusions self-administered (percent change: 24.97+/-10.65, P=0.04, Coh

205 suggests that a step-wise increase in daily administered primaquine dose would be relatively safe in

206 role in the efficient propagation of orally administered prions toward FDC within Peyer's patches in

207 y of a single dose of GAG from a SELP matrix administered prior to irradiation significantly reduced

208 h) efficacy and safety of ranibizumab 0.5 mg administered pro re nata (PRN) with or without laser usi

209 ents, but HBIG is costly and inconvenient to administer, prompting consideration of alternative regim

210 sessed at each assessment with the Clinician-Administered PTSD Scale.

211 tamine (Glx) were measured using a clinician-administered questionnaire, fMRI during performance of a

212 udy participants completed an anonymous self-administered questionnaire, to collect data on their soc

213 lth data were collected using an interviewer-administered questionnaire.

214 Masked interviewers administered questionnaires by telephone before and afte

215 h malaria rapid diagnostic tests (RDTs), and administered questionnaires on ITN use and other risk fa

216 Results showed that in CAF administered rats the maximum time of plasma flavanol co

217 % CI -5879 to -216; p=0.0362) fewer vaccines administered, respectively.

218 NMNAT2 positive-modulator, when systemically administered restored NMNAT2 expression in rTg4510 tauop

219 ca ochengi that elevated exposures of orally-administered rifampicin can lead to Wolbachia depletions

220 lications for humans; however, rats and mice administered scopolamine showed increased anxiety in sta

221 ermined whether avacopan (CCX168), an orally administered, selective C5a receptor inhibitor, could re

222 ountries and territories (which collectively administered several hundred million doses of tOPV each

223 Stress administered shortly after threat conditioning did not a

224 Intratracheally administered sildenafil particles elicited more pulmonar

225 Orally administered small-molecule inhibitors that suppress inf

226 t extinction often fails to reduce fear when administered soon after trauma.

227 ing, and both mechanisms can be inhibited by administering specific molecules to prevent induction of

228 colon cancer through the creation of orally administered squalenoylated nanoparticles loaded with ci

229 Intranasally administered ST266 accumulated in rodent eyes and optic

230 Four tests were administered (Stroop color word test, letter-digit subst

231 Tildrakizumab was administered subcutaneously at weeks 0 and 4 during part

232 40 mg, according to body weight) or placebo, administered subcutaneously every 2 weeks.

233 toward the potential benefits of a federally administered system in which all patients are treated un

234 red and seventeen patients were using a self-administered systemic therapy; 22.4% were classified as

235 As GLP-1 mimetics are administered systemically in humans, we evaluated whethe

236 In contrast, only memantine, administered systemically or intra-PLmPFC, interacted wi

237 ageenan- or FCA-induced pain in rodents when administered systemically.

238 leted in Aggrecan-expressing chondrocytes by administering tamoxifen at 8-weeks of age.

239 se, we used diet-induced obese rats and rats administered thapsigargin, and by combining metabolic, h

240 ps in the proportion of isotonic crystalloid administered that was saline.

241 r 65 years, and were not already planning to administer the high-dose influenza vaccine to residents.

242 gated catalase to anti-ICAM-1 antibodies and administered the conjugate to 8 wk old C57BL/6J mice 30

243 les to carry specific nucleic acid barcodes, administered the pool of particles, and quantified parti

244 t allocation, and an unmasked team of nurses administered the vaccines.

245 KYNA levels were enhanced by administering the kynurenine 3-monooxygenase (KMO) inhib

246 e, this secondary analysis demonstrates that administering the vaccine to children in the months prio

247 asures were the suicide items from clinician-administered (the Montgomery-Asberg Depression Rating Sc

248 ons, and differences in antibiotic treatment administered, the odds of dying within 14 days were more

249 their own injections and were encouraged to administer them on the same day of each week in the same

250 stinal enzyme that oxidizes more than 60% of administered therapeutics.

251 ne of leptin with Pluronic P85 (LepNP85) and administered this conjugate intranasally using the nose-

252 rst line ALK TKI therapy, another ALK TKI is administered, though collateral sensitivity is not consi

253 st cytotoxic effect on MM cells when BTZ was administered through anti-CD38 chitosan NPs.

254 e, they remain easily suspended, handled and administered through standard microcatheters.

255 (2 puffs of 1.25 mug), or placebo (2 puffs), administered through the Respimat device as add-on to ba

256 sed using repeated 24-hour recalls that were administered throughout pregnancy.

257 Novel but pretested survey tools were administered to 129 patient-parent dyads of hospital-bas

258 Mock page cases (n = 16) were administered to 213 senior medical students from 12 medi

259 uorescens and Flavobacterium johnsoniae were administered to 240 tadpoles of the midwife toad, Alytes

260 Resting-state fMRI was administered to 33 cirrhotic patients with MHE and 43 ci

261 10(13) genome copies of AMT-060/kilogram was administered to 5 participants each.

262 69 (48.6%), with additional systemic agents administered to 54 patients (38.0%).

263 Dantrolene is administered to alleviate MH symptoms, but its mechanism

264 ed concentrations of xDP, xFP, and waDP were administered to chicken and double-crested cormorant hep

265 acterial species from this family, that-when administered to colitis-prone mice-protected them agains

266 nnaire that addressed patients' concerns was administered to consecutive glaucoma patients.

267 imiting angina, sublingual nitroglycerin was administered to half the patients, and all patients cont

268 Finally, ARVs administered to mice and SIV-infected macaques resulted

269 1) was also observed when the particles were administered to mice bearing the same tumours 20min prio

270 Allergen-specific IgG was administered to mice undergoing sensitization and desens

271 ng and prolonged oral environmental toxicity administered to mutant knockin LRRK2 mice over half thei

272 inical studies suggest that anesthetic drugs administered to neonatal animals cause widespread neuron

273 ucose tolerance and insulin sensitivity when administered to obese recipients.

274 efully considered, as such inhibitors can be administered to patients for years.

275 AZD3759 at 200 mg or 300 mg twice a day was administered to patients with either brain or leptomenin

276 When administered to rabbit and monkey eyes, the half-life of

277 IFN-gamma blocking antibody administered to Sphk2(-/-) mice or deletion of Ifng (Sph

278 The Glasgow Sensory Questionnaire (GSQ) was administered to synaesthetes and people with ASC.

279 irus (rAAV5-hSyn-EGFP) were stereotactically administered to the hypoglossal nucleus of C57BL/6J mice

280 ally, vectors were switched and systemically administered to the reciprocal group of animals.

281 ally restored the number of kidney MPCs when administered to THP(-/-) mice.

282 ethasone) and magnesium sulphate (MgSO4) are administered to women in preterm labor to reduce neurolo

283 this limitation to a substantial degree when administered together with the nanoparticles.

284 , who are the seed nodes and responsible for administering treatments.

285 d, and mood and psychological batteries were administered under four stimulation conditions: VIM on,

286 In the first 2 parts, the radiotracer was administered using a bolus-plus-infusion protocol, the a

287 Surveys at each stage were administered via an online survery software tool.

288 tial CT attenuation scan, (11)C-nicotine was administered via intravenous injection.

289 he highest tumor uptake was observed in mice administered with (111)In-D2B-DAR2-MMAE, reaching 119.7

290 onal antibodies against a viral antigen when administered with a needle-free device, although not whe

291 mune destruction was also diminished in mice administered with an anti-CXCL10 antibody.

292 protocol was identified as activated MSC co-administered with antibiotic therapy.

293 as a fixed-dose combination to dolutegravir administered with coformulated emtricitabine and tenofov

294 arm we assessed the response to IM injection administered with electroporation (EP).

295 High-dose intravenous NAC administered with low-dose intravenous nitroglycerin is

296 more serial injections of macrocyclic GBCAs administered with on average 3 months between each injec

297 igh [HFD], medium [MFD], and low [LFD]) were administered with or without the supplementation of Lact

298 However, when administered with subtherapeutic doses of opioids or the

299 was enhanced by >13days compared to controls administered with the drug solution only.

300 Sevoflurane was administered with the MIRUS system targeted to a Richmon

301 lr(-/-)) mice on a high-fat diet were orally administered with vehicle control or UFP (40 mug/mouse/d

302 Two AFR treatments were administered within an area of FDH.