ライフサイエンスコーパス: administration

1 n vivo half-life is an obstacle to long-term administration.

2 in 18 (rIL18) or saline (control) during DSS administration.

3 ted by 1 minute, followed by a 500-mL saline administration.

4 and monkeys, but did not affect cocaine self-administration.

5 induced gastrointestinal AEs than did weekly administration.

6 medication event-monitoring devices for self-administration.

7 l, gastrointestinal, ungual and vaginal drug administration.

8 ]), obtained for up to 1 week after ketamine administration.

9 orting painless and non-invasive transdermal administration.

10 re significantly decreased after bolus fluid administration.

11 duration is affected by gadoxetate disodium administration.

12 mias and lower mortality after isoproterenol administration.

13 cifically reach tumors following intravenous administration.

14 d 7.3x and 4.1x, respectively, at 24 h after administration.

15 proved for treatment by the US Food and Drug Administration.

16 ion for regions most relevant in intrathecal administration.

17 hment-induced suppression of aggression self-administration.

18 Plasma levels were obtained 2.5 h post administration.

19 increased after 6- and 12-month ethanol self-administration.

20 pated and suggest promising potential for QD administration.

21 nd the effects of some drugs on cocaine self-administration.

22 distress associated with nanopharmaceutical administration.

23 aqueous solubility suitable for intravenous administration.

24 ng sex steroid inhibition and growth hormone administration.

25 e tested as Lf encapsulation system for oral administration.

26 via endotracheal (ET) or intravascular (IV) administration.

27 had blood draws before and after medication administration.

28 de the CNS via multiple routes of peripheral administration.

29 rain parenchyma away from the point of local administration.

30 by measuring plasma HIV-1 RNA during MGN1703 administration.

31 ner and showed no accumulation with repeated administration.

32 nitrobenzenesulfonic acid in rats after oral administration.

33 ht examples of inter-organ responses to drug administration.

34 was higher in the THW-aided than rhTSH-aided administrations.

35 larger under pathological conditions or drug administrations.

36 also significantly decreased after anti-IgE administration 24 hour and 48 hour after the last AP cha

37 Folic acid administration 6 or 7 times per week protected more agai

38 ons were performed under intravenous alcohol administration (6% vol/vol infusion to achieve a target

39 eived further medical prescriptions for self-administration: 67% corticosteroids, 83% antihistamines,

40 ient by applying the 2016 U.S. Food and Drug Administration accuracy criteria, determining mean absol

41 ti-compartment compliance aids on medication administration accuracy.

42 The Food and Drug Administration Adverse Event Reporting System (FAERS) re

43 llum), or of the effects of chronic ketamine administration, although consistent increases in cortica

44 Intranasal (IN) administration, an alternative route for non-invasive dr

45 cine could be used for combination mass drug administration and a mass vaccination program approach t

46 n of < 9 mug/dL) after cosyntropin (250 mug) administration and a random plasma cortisol of < 10 mug/

47 otor activation in response to acute cocaine administration and an altered locomotor sensitization pr

48 Both intranasal oxytocin administration and chemogenetic stimulation of oxytocin

49 ce were infected with H1N1 PR8 by intranasal administration and course of influenza pneumonia, inflam

50 Alcohol self-administration and cue-induced reinstatement behavior wa

51 After chronic cocaine administration and following withdrawal, an acute cocain

52 nd emergency department delays in antibiotic administration and in-hospital mortality among patient e

53 Prompt antitoxin administration and meticulous intensive care are essenti

54 ted cocaine seeking in a mouse model of self-administration and relapse, and found that either increa

55 the FST group) withdrew consent before drug administration and was excluded from analysis.

56 ation between the number of macrocyclic GBCA administrations and DeltanSIDN or DeltanSIDNavg.

57 ticipants stayed overnight after the alcohol administration, and discharge occurred on day 7 of the p

58 Analysis of rates and predictors of albumin administration, and estimated costs.

59 ceptability of multiple injections, sites of administration, and safety.

60 New supplemental US Food and Drug Administration approvals, new off-label indications, and

61 In February, 2017, the US Food and Drug Administration approved the blood infection marker proca

62 In April 2016, the Food and Drug Administration approved the first biosimilar monoclonal

63 Clofazimine is a weakly basic, Food and Drug Administration-approved antibiotic recommended by the Wo

64 urposing screening to identify Food and Drug Administration-approved chemotherapeutic compounds posse

65 fectiveness and safety of U.S. Food and Drug Administration-approved devices.

66 hase II to IV cancer trials of Food and Drug Administration-approved immunotherapy drugs and selected

67 ity or adverse immune consequences of vector administration are observed.

68 essed the effect of lipopolysaccharide (LPS) administration at a dose of 2 ng/kg of body weight on mo

69 International support for mass drug administration, bed nets, and other preventive measures

70 comes included blood culture use, antibiotic administration between 24 and 72 hours, clinical outcome

71 serum prolactin levels following Opra Kappa administration, but modest increases in circulating adre

72 ontrol, significantly decreased cocaine self-administration by 67% relative to baseline at greater th

73 rthotopic rat brain tumors in vivo following administration by convection enhanced delivery.

74 Increasing distance to the closest Veterans Administration center was associated with decreased PTUD

75 e data necessary to support US Food and Drug Administration clearance of new diagnostic tests by prom

76 infective costs be measured by patient-level administration data normalized for patient census.

77 Moreover, ketamine administration decreased the expression of urothelial ba

78 d preference in response to low-dose cocaine administration did not differ between genotypes.

79 Furthermore, PFT-mu administration did not impair the anticancer efficacy of

80 uted on the epicardium following pericardial administration, displaying a half-life of 2.5days in th

81 hemotherapy drugs can be used to reduce drug administration dose.

82 ats at 24 h withdrawal from systemic ethanol administration (either by intraperitoneal injection, 2 g

83 Cocaine self-administration elevated BNST PACAP, and BNST PACAP recep

84 Their intraperitoneal administration enabled triggered release of the active M

85 We demonstrated that kisspeptin administration enhanced limbic brain activity specifical

86 The medication administration error rate was calculated as the number o

87 rtunities for error (7.1% overall medication administration error rate).

88 ifferences existed when comparing medication administration error rates between original medication p

89 One hundred and seventy eight medication administration errors were identified from 2493 opportun

90 of Cancer Research, and the US Food and Drug Administration examined specific eligibility criteria (i

91 Upon systemic administration, exogenous Mn exhibited varying transport

92 Exogenous R-spondin administration expands and accelerates proliferation of

93 ning conditions can receive US Food and Drug Administration (FDA) accelerated approval based on showi

94 s that were approved by the US Food and Drug Administration (FDA) and required pharmacogenomic biomar

95 LAAC) was approved by the U.S. Food and Drug Administration (FDA) as a stroke prevention alternative

96 ll products fell within the US Food and Drug Administration (FDA) average bioequivalence (ABE) accept

97 n/Spinraza) was approved by US Food and Drug Administration (FDA) in late 2016 and several other comp

98 ells using a library of 106 US Food and Drug Administration (FDA)-approved anticancer drugs or compou

99 ineurin, with low doses of the Food and Drug Administration (FDA)-approved compound Tacrolimus, block

100 mcitabine and several other US Food and Drug Administration (FDA)-approved oncology drugs.

101 st in goal-directed, restricted-volume fluid administration for major surgery, there remains little c

102 tests are cleared by the U.S. Food and Drug Administration for use with extragenital swab samples.

103 ralasia, and North America from their prison administrations for 2011-14 to calculate suicide rates a

104 e controls submitted to the US Food and Drug Administration from January 1, 2003, through December 31

105 examined the impact that prior cocaine self-administration had on firing in dorsal lateral striatum

106 stay the rule, and the subsequently elected administration has now placed it under review for potent

107 -DOTATATE approval by the U.S. Food and Drug Administration has triggered widespread clinical interes

108 Although a qualified Food and Drug Administration health claim exists for nuts and heart he

109 d excellent muscle transduction following IP administration, highlighting its potential as a new musc

110 OPD, and (2) to test whether low flow oxygen administration improves endothelial function and is prot

111 neuroprotective regimen suitable for prompt administration in emergency departments.

112 In conclusion, daily sulindac administration in FAP patients significantly altered col

113 ory effects in vitro, but not following oral administration in humans.

114 C646 administration in mice afflicted with p53-mutant tumors

115 Systemic administration in mice followed by local light-emitting

116 without inducing motor dysfunction after sc administration in mice.

117 ls ex vivo, followed by intramyocardial cell administration in normal and infarcted mice.

118 ective to reduce food intake within hours of administration in overweight, rather than lean, mice.

119 ment with Ro 61-8048 decreased nicotine self-administration in rats and monkeys, but did not affect c

120 s to a concentration-time profile after oral administration in the cynomolgus monkey that showed a ve

121 The primary outcome was antibiotic administration in the first 24 hours.

122 (Nandrosol) and the beta-agonist ractopamine administration in veal calves, and it investigates diffe

123 Both drugs attenuated alcohol self-administration in Wt rats but not in NOP (-/-) rats.

124 d to without, had lower rates of epinephrine administration (incidence rate per 10,000 students 0.2 a

125 The United States Food and Drug Administration is concerned about the presence of these

126 ologic MR neuroimaging findings (and no GBCA administration), matched for age and sex, were inculded.

127 hotspots have been described after mass drug administration (MDA) for the control of schistosomiasis,

128 2015, 1522 patients at 35 US Veterans Health Administration medical centers who were diagnosed with n

129 A rat heroin self-administration model was used to obtain translational mo

130 and relapse-like behaviors in a cocaine self-administration model.

131 Drug self-administration models of addiction typically require ani

132 use process node (prescribing, distribution, administration, monitoring).

133 After administration of (11)C-MeNER, 15 nondemented patients w

134 They underwent PET/CT after the administration of (68)Ga-THP-PSMA.

135 These results suggest that administration of 5-FU followed by GDC-0941 may suppress

136 l sensation during cold stress following the administration of a graded thermal stimuli delivered to

137 onducted in human subjects demonstrated that administration of a highly purified (>95%) short-chain g

138 ned weight reduction in response to systemic administration of a long-acting analog of the gut-hormon

139 Subcutaneous administration of ALN-GO1 resulted in potent, dose-depen

140 by reducing the neutrophil load with in vivo administration of an anti-Ly6G antibody.

141 Administration of an anti-PAR2 antibody, SAM-11, after t

142 longed circulation of the dendrimer, enabled administration of an efficacious dose of SN-38, achievin

143 randomized controlled trial to test whether administration of an extensively hydrolyzed casein formu

144 Administration of an inhibitor to cyclooxygenase-2, the

145 As we expected, systemic administration of anti-DC-STAMP-mAb downregulated the li

146 1.05; P<0.001), as was a longer time to the administration of antibiotics (odds ratio, 1.04 per hour

147 We also examined the times to the administration of antibiotics and to the completion of a

148 ion is essential to ensure early appropriate administration of antibiotics to save lives of patients,

149 essor response than lactic acid alone, while administration of APETx2 inhibited endomorphin's enhanci

150 Oral administration of azithromycin definitively decreases th

151 We suggest that administration of B. subtilis EPS can be used to broadly

152 targeting inflammatory cytokines and by the administration of beneficial commensal Lachnospiraceae i

153 Administration of bictegravir, a novel, potent, once-dai

154 Weekly administration of bortezomib enhanced tolerability and c

155 1441 dose-dependently decreased alcohol self-administration of both dependent and non-dependent anima

156 Intrathecal administration of BzATP resulted in ROS production in th

157 In mouse xenograft models of human TNBC, administration of C1572 suppressed tumor growth and depl

158 Administration of CD5-2 in tumor-bearing mice enhanced e

159 Administration of CDCexo but not Fbexo after reperfusion

160 In this article, we show that administration of cGAMP, delivered by an ultra-pH-sensit

161 l different forms of TBI in humans, and that administration of cis P-tau targeting antibody to rodent

162 Acute administration of clozapine rapidly increased extracellu

163 Systemic administration of CTDP-32476 alone produced a slow-onset

164 r) under Cu deficiency and that subcutaneous administration of Cu to these animals restore normal ATP

165 Oral administration of Cu(II)(atsm) delayed the onset of neur

166 Administration of D-4F or E06 to rats profoundly amelior

167 In this regard, administration of d-cycloserine (DCS), which is a glycin

168 ngs suggest that therapeutic or prophylactic administration of defined bacterial consortia to individ

169 In anesthetized guinea pigs intratracheal administration of DEPs activated airway C-fibers.

170 estinal homeostasis abnormalities after oral administration of dextran sodium sulfate (DSS).

171 Administration of dibutyl phthalate (DBP) to pregnant ra

172 Anln mRNA developed fewer liver tumors after administration of diethylnitrosamine and carbon tetrachl

173 8 expression in vivo in splenic DC following administration of dimethyl PGE2 in conjunction with LPS.

174 Similarly, administration of either GSK2656157 or overexpression of

175 red drug effects to adverse events following administration of either therapeutic or toxic doses, in

176 take of (11)C-erlotinib was not higher after administration of elacridar.

177 an emergency treatment plan and training in administration of emergency medication.

178 Oral administration of ERG240 reduces the severity of collage

179 Administration of ESAT-6 but not CFP10 induced STAT3 pho

180 d under control conditions and following the administration of etanercept (TNF-alpha inhibitor; 1 mg

181 developed less-severe liver injury following administration of ethanol, injection of anti-MIR122, or

182 on based on baseline risk factors and age of administration of exogenous hormones because of concern

183 Finally, the administration of exogenous NGF to wild-type mice was fo

184 Administration of FGF2 neutralizing antibody to mice bea

185 Calmette-Guerin needles and syringes for the administration of fIPV.

186 The administration of FR167653, p38 MAPK inhibitor, reduced

187 Intrascrotal administration of Gal-3 to CX3CR1(gfp/+) mice confirmed

188 of the DN and GP that are independent of the administration of GBCA occur in patients with brain tumo

189 Moreover, the administration of GOS and the FOS+GOS combination reduce

190 These data suggest that administration of high-dose loop diuretics to patients w

191 The administration of IAP or the antiviral neuraminidase inh

192 Fractional-dose administration of inactivated poliovirus vaccine (fIPV)

193 ypes of ASD, to test the effects of systemic administration of insulin-like growth factor II (IGF-II)

194 ed risk for developing renal toxicity due to administration of intravenous iodine- and gadolinium-bas

195 This may be important, since the administration of lactate during hypoglycemia suppresses

196 Intra-arterial administration of lactic acid (to simulate exercising mu

197 elevated protein in the CNS after peripheral administration of lipopolysaccharide (LPS).

198 g elimination from the circulation after the administration of liposomal formulation was characterize

199 d of having RVH or obstruction compared with administration of lower doses; unnecessary radiation exp

200 The administration of mannitol 24h after BCM-PTX injection f

201 Administration of Manoalide, a PLA2 inhibitor or Zileuto

202 We find that systemic administration of MS0021570_1 attenuates anxiety-like be

203 iants (MSC-oHSV) and found that intracarotid administration of MSC-oHSV, but not of purified oHSV alo

204 racts the behavioral effects of the systemic administration of mu-opioid receptor (MOR) agonists.

205 lated analgesia is reversible by intrathecal administration of naloxone, suggesting an opioid-mediate

206 G-CSF); these effects are reversed following administration of neutralizing anti-G-CSF antiserum.

207 Administration of nitroglycerin causes changes in the sy

208 Here, we show that intracortical administration of NR but not NAD(+) reduces brain damage

209 This suggests that peripheral administration of OT does not lead to central release of

210 Oral administration of ovalbumin (OVA) in Was(-/-) mice induc

211 Although pharmacological administration of oxytocin has implicated this neuropept

212 mine the cost-effectiveness of perioperative administration of pasireotide for reduction of pancreati

213 In conclusion, compared with placebo, administration of perioperative THR-184 through a range

214 est that in these inflammatory models, acute administration of peripherally restricted NaV1.7 inhibit

215 This effect could partly be reversed by administration of PGE2 to COX-2 mice.

216 By contrast, administration of precocene-I (a JH inhibitor) had a ten

217 cquisition of resistance can be modulated by administration of pro- and antiquorum-sensing compounds.

218 Exogenous administration of recombinant CCL5 to C3aR-deficient mic

219 s 1, 3, and 4 received a single subcutaneous administration of RG-101 at 2 mg/kg (n = 14) or 4 mg/kg

220 In the caerulein-induced murine model of CP, administration of ruxolitinib for one week significantly

221 Intraperitoneal administration of S17 significantly inhibited the growth

222 P < 0.05) than the values measured after the administration of Sandostatin LAR.

223 e, dose, related adverse events and route of administration of sedatives as well as image quality.

224 Administration of soluble beta-glucans or a SYK inhibito

225 Furthermore, administration of SPHK1 inhibitors to orthotopic AML pat

226 Elimination of these reservoirs through the administration of synergistic combinations of latency re

227 diabetic (NOD) mouse model reported mucosal administration of T1D-related autoantigens [proinsulin o

228 Co-administration of TGF-beta shRNA and HBV dual-shRNA decr

229 onstrate, for the first time, that transient administration of the cannabinoid receptor 2 antagonist

230 In a population-based study, we associated administration of the cholera vaccine after CRC diagnosi

231 The administration of the ESA epoetin alfa to critically ill

232 al coherence before and 90 minutes after the administration of the first MPH dose to 40 stimulant dru

233 Administration of the kappa-opioid receptor (KOR) antago

234 linium was two- to fourfold higher following administration of the linear agents gadodiamide and gado

235 Oral administration of the plasmid DNA (pDNA) encoding GLP-1

236 r an experimental study involving sequential administration of then-standard influenza vaccines.

237 another set of control and hREG3A-TG mice by administration of trinitrobenzene sulfonic acid; some mi

238 RATIONALE: Administration of tuberculosis (TB) vaccines in particip

239 Oral administration of vancomycin greatly dampened both CT im

240 etermine the immunomodulatory effect of oral administration of vitamin D-enriched mushrooms extracts

241 Intraperitoneal administration of Z2 inhibits vertical transmission of Z

242 l of CIDP to date and the first to study two administrations of immunoglobulins and two doses, showed

243 nuates anxiety-like behavior while intra-BLA administration or knockdown of GPR171 in the BLA reduces

244 ot identify deviations from US Food and Drug Administration or manufacturer recommendations for repro

245 also found no sex differences in heroin self-administration or the strong preference for the palatabl

246 in male mice through central pharmacological administration or virally mediated hypothalamic overexpr

247 elation was found between the number of GBCA administrations or the total amount of GBCA administered

248 rapies in AF) study from the Veterans Health Administration, patients with newly diagnosed, nonvalvul

249 uninhibited alloreactivity, exogenous IL-22 administration posttransplant resulted in increased reco

250 palatable food was enhanced in operant self-administration procedures.

251 After cerulein administration, Ptf1a-Cre(ERTM);LSL-Kras(G12D) mice form

252 Food and Drug Administration published new, more stringent guidelines

253 t-free classrooms did not affect epinephrine administration rates.

254 In a substitution test, cocaine self-administration rats displayed a progressive reduction in

255 or omitted) in error according to medication administration records, compared to the opportunities fo

256 imultaneously or 18 h prior to systemic AMPH administration reduced both AMPH-stimulated dopamine ove

257 ches, and complaints to the US Food and Drug Administration regarding generic products.

258 deficits, but the proposed US Food and Drug Administration regulations may severely limit the abilit

259 s, focusing on whether they reduce drug self-administration, reinstatement of drug seeking, and incub

260 However, due to inadequate drug administration reporting, it was generally unclear if ou

261 nd 0% of mice with Salmonella and Klebsiella administrations, respectively.

262 o 16% of mice with Klebsiella and Salmonella administrations, respectively.

263 Cytokine administration resulted in significant reversal of bioch

264 pecimens with comparable contrast to in vivo administration routes, and demonstrate the feasibility o

265 s that compared different doses of naloxone, administration routes, or transport versus nontransport

266 The US Food and Drug Administration's updated nutrition labeling requirements

267 ns in reward circuits following cocaine self-administration (SA) underlie reinstatement of drug-seeki

268 od was then restricted to daily operant self-administration sessions using fixed ratio 1, 3, and 5 an

269 FPS-ZM1 administration significantly reversed emphysema in the l

270 IV-1 RNA at week 48 (by the US Food and Drug Administration snapshot algorithm), with a prespecified

271 at week 48 (assessed by the US Food and Drug Administration snapshot algorithm), with a prespecified

272 0 copies per mL at week 48 (US Food and Drug Administration snapshot algorithm), with a prespecified

273 receptors (nAChRs) can reduce nicotine self-administration, suggesting that a positive allosteric mo

274 lucidate a novel mechanism whereby oral AM80 administration suppressed lung mucosa-associated Tfh and

275 s that used a combination of both medication administration systems (RR=4.3, 95%CI 2.7 to 6.8, p<0.00

276 and intake of cocaine in an intravenous self-administration test.

277 illance, using data from the Veterans Health Administration, the largest provider of liver-related he

278 erties of this tracer mean that through oral administration, the turnover and flux through a number o

279 We track routine mass drug administration-the large-scale distribution of deworming

280 yes = PLEX(+) , no = PLEX(-) ) and steroids administration timing (prophylactically [proST] or thera

281 f relapse after extinction from cocaine self-administration to assess how cocaine use affects t-SP as

282 lowing single oral (PO) and intravenous (IV) administration to cockatiels (Nymphicus hollandicus).

283 acokinetic evaluation of empagliflozin after administration to Egyptian volunteers, and the results w

284 treatment, data do not support delaying HBAT administration to perform ST in a mass botulinum toxin e

285 Intracerebroventricular administration to rats of a single small dose of Hi1a (2

286 t and has been approved by the Food and Drug Administration to treat refractory multiple sclerosis.

287 s of the study drugs by the US Food and Drug Administration) to May 19, 2016.

288 ly, to our knowledge, the shortest effective administration-to-birth interval is unknown.

289 for five consecutive days during which self-administration took place in the morning.

290 s often via the parenteral route, reliant on administration using hypodermic needles, which can be as

291 doscopy has increased in the Veterans Health Administration (VHA) as in fee-for-service environments,

292 lar cortex) brain regions following oxytocin administration vs placebo.

293 Mass drug administration was predicted to be more effective if con

294 mulates an intervention similar to mass drug administration, we argue that the observed repertoire st

295 -MSNs blocks drug seeking after cocaine self-administration, while enhancing the fission promoting Dr

296 d a progressive reduction in CTDP-32476 self-administration with an extinction pattern of drug-taking

297 model of the association correlation of ECT administration with patient risk of 30-day readmission w

298 All the DC-targeting vaccine administrations with poly-ICLC increased the low-level s

299 antenatal management in FNAIT is weekly IVIG administration, with or without the addition of corticos

300 = 1.22 [1.09-1.36]; p = 0.0006), antibiotic administration within 6 hours (relative risk = 0.20 [0.0