ライフサイエンスコーパス: admix

1 pressed (P > 0.05) in rats fed bosentan chow admix.

2 s either in an AB5 structure or with A and B admixed.

3 rats preventatively treated with a chow LPA admix (400 mg/kg per chow).

4 Interestingly, this paramagnetic state admixes a zig-zag spin mode analogous to the zig-zag ord

5 Admixing a variety of aldehydes, dimethyl 2-aminomalonat

6 In admixed African Americans and Hispanic/Latino Americans,

7 al and clinical cardiovascular disease among admixed African Americans compared with other population

8 c basis of variation in renal function among admixed African Americans.

9 y disease discovered by admixture mapping in admixed African Americans.

10 a population-based sample of 1,018 unrelated admixed African Americans.

11 We observed a decline in heterozygosity in admixed Africans and found that the Eurasian admixture c

12 th admixture, depending on the origin of the admixed alleles and the relative magnitude of the diseas

13 address the implications of the creation of admixed American genomes, containing novel allelic combi

14 ed groups--populations that have experienced admixing among continentally divided ancestral populatio

15 APAA (HMM-based analysis of polymorphisms in admixed ancestries), that models the allelic and haploty

16 erences of parental and first generations of admixed ancestries.

17 Our sample includes 12 individuals who have admixed ancestry and who have varying degrees of recent

18 A chromosome in an individual of recently admixed ancestry resembles a mosaic of chromosomal segme

19 As a result of their equally balanced admixed ancestry, the Malagasy may represent an ideal po

20 g relatedness in structured populations with admixed ancestry.

21 or European ancestry groups reflected their admixed ancestry.

22 gtze River, each one connected to a group of admixed ancestry.

23 y detected down to 0.01ng DNA and 1% meat in admixed and burger products.

24 nd 3-aminopropyltriethoxysilane (APTES) were admixed and covalently attached to a polystyrene based-m

25 The population is highly admixed and has a cohesive and conservative lifestyle.

26 the genomes of individuals of P. formosa are admixed and intermediate between Poecilia latipinna and

27 te the genetic correlation structure of both admixed and non-admixed individuals using simulated and

28 Of the four herds, two appeared to be admixed and two were nonadmixed.

29 ferent population structures (admixed or non-admixed) and relatedness (related or independent).

30 hich induce immune responses directed at the admixed antigens.

31 roups, we allow each ancestral population to admix at a different time in history.

32 nd gangliosides, and even in the presence of admixed B subunit, it displayed low cyclic AMP (cAMP) in

33 ut substantially less accurate in samples of admixed background such as African Americans.

34 m European stock, whereas others are clearly admixed between indigenous and European dogs.

35 d control rats fed normal chow or a bosentan admix both produced similar (P > 0.05) panretinal DeltaP

36 uman breast carcinomas promote the growth of admixed breast carcinoma cells significantly more than d

37 U.S. populations are genetically admixed, but surprisingly little empirical data exists d

38 average fitness and population viability of admixed California Tiger Salamanders may be enhanced.

39 rican Americans, Hispanics, East Asians, and admixed cases and controls were successfully genotyped.

40 ematical connection between the discrete and admixed cases, we show that in admixed populations, spur

41 i were differentially retained in the modern admixed Colombian population based on their utility in t

42 human health and fitness via analysis of an admixed Colombian population from Medellin.

43 er" subjects whose ethnicity is different or admixed compared to most other subjects in the genotyped

44 genetic markers and speech recordings in the admixed creole-speaking population of Cape Verde, whose

45 ither a member of such a population or is an admixed descendant of them.

46 nt with water ice that has approximately 15% admixed dust.

47 Admix'em is designed to simulate selection in admixed po

48 We introduce a new forward-time simulator, Admix'em, that allows for rapid and realistic simulation

49 Pharmacogenetic studies of admixed ethnic groups have been limited to small candida

50 y of localizing genes that cause disease, in admixed ethnic groups such as African Americans, with ap

51 Hispanics/Latinos and African Americans and admixed Europeans, Africans, and Asians.

52 and elaborate proinflammatory mediators with admixed features of Th1 and Th2 responses.

53 of our approach is that it incorporates the admixed genomes themselves jointly with public datasets,

54 rmance over existing approaches in sequenced admixed genomes.

55 on owing to heterogeneity in ancestry within admixed groups [25, 26] and idiolectal variation owing t

56 tobacco-derived biomarkers in smokers from 3 admixed groups in the Multiethnic Cohort Study (1993-pre

57 genomewide studies have focused on recently admixed groups--populations that have experienced admixi

58 nant haplotype of population 1 (3D7) and one admixed haplotype of population 5 (FVO) were tested for

59 haplotypes represented in other populations (admixed haplotypes).

60 ile but also conferred increased motility to admixed HeLa cervical cancer cells.

61 102 (9.9%) persons of genetically determined admixed Hispanic ancestry had more impairment by GDS or

62 In multivariate models including persons of admixed Hispanic ancestry, those with haplogroup B had l

63 rican, European, and African segments of the admixed Hispanic/Latino genomes.

64 nd that patterns of linkage-disequilibria in admixed Hispanic/Latino populations are largely affected

65 used a large panel of pedigreed, genetically admixed house mice to study patterns of recombination ra

66 his visualization of the mosaic structure of admixed human chromosomes gives results similar to anoth

67 The use of admixed human populations to scan the genome for chromos

68 the widespread study of genetic variation in admixed human populations, such as African-Americans, th

69 urs on one-electron oxidation, leading to an admixed hybrid orbital for the cation radical form.

70 All five serrated adenomas with admixed hyperplastic glands and adenomatous glands were

71 to 10) hyperplastic polyps, including 5 with admixed hyperplastic glands and adenomatous glands, and

72 ancer, and in 70 HPs, 4 serrated adenomas, 3 admixed hyperplastic-adenomatous polyps, 10 tubular aden

73 radic HPs), 75% of serrated adenomas, 33% of admixed hyperplastic-adenomatous polyps, 30% of tubular

74 ew estimators exist for individuals that are admixed, i.e. have ancestry from more than one populatio

75 ation, indicating that sporadic cases can be admixed in with Lynch syndrome cases, even those meeting

76 By analyzing polymorphisms in the admixed individual against those seen in representatives

77 ferring ancestry along the chromosomes in an admixed individual and thereby delineating the ancestry

78 The genome of an admixed individual with ancestors from isolated populati

79 y admixed population, when the phase of each admixed individual's genotype relative to the pair of lo

80 e ancestry of each chromosomal segment in an admixed individual.

81 stry at each locus in the genome of recently admixed individuals (e.g., Latino Americans) plays a maj

82 mpowering disease mapping studies in African-admixed individuals and will facilitate gene discovery f

83 ates of the genome-wide average ancestry for admixed individuals are consistent between exome sequenc

84 ancestry of specific chromosomal regions in admixed individuals are useful for studies of human evol

85 The inference of local ancestry of admixed individuals at every locus provides the basis fo

86 in whole blood and colorectal tissue of 132 admixed individuals from Colombia, we identified sites w

87 s consensus local ancestry calls in the real admixed individuals from the 1000 Genomes Project.

88 Placement of admixed individuals on the landscape is more complicated

89 ves better localization for both unmixed and admixed individuals than existing methods despite using

90 this overestimation is larger for samples of admixed individuals than for samples of unadmixed indivi

91 xplore the use of local ancestry in recently admixed individuals to find signals of gene-gene interac

92 ry inherited from parental populations among admixed individuals to map associations for diseases, th

93 orrelation structure of both admixed and non-admixed individuals using simulated and real data.

94 two genetic clusters, within which the least admixed individuals were found in Europe/central Asia an

95 Inferring the ancestry of each region of admixed individuals' genomes is useful in studies rangin

96 sweet orange, is the offspring of previously admixed individuals, but sour orange is an F1 hybrid of

97 In sequence association studies of admixed individuals, cryptic relatedness and population

98 y or used for genetic association studies in admixed individuals.

99 terns of ancestry segments in chromosomes of admixed individuals.

100 s classifier to infer the local ancestry for admixed individuals.

101 observation of ancestry switch points among admixed individuals.

102 spersed within the chromosomes of ethnically admixed individuals.

103 ly migrants to Africa, and non-native, breed-admixed individuals.

104 distinct subpopulations or a single pool of admixed individuals.

105 pulation of origin of chromosomal regions in admixed individuals.

106 ancestral origins of chromosomal segments in admixed individuals.

107 re available for inferring local ancestry in admixed individuals.

108 ver genes influencing skin colour in African-admixed individuals.

109 irwise relatedness from genetic data between admixed individuals.

110 software has a capacity for analyzing 6-way admixed individuals.

111 ng populations, except between the large and admixed interior populations.

112 (26)Al radionuclide is thought to have been admixed into the initially (26)Al-poor protosolar molecu

113 to differentiate between forest, savanna and admixed isolates, which has not previously been possible

114 CD4(+) T cells, and an inhibitory effect on admixed lymphocytes.

115 Overall, the admixed map is well predicted by the average proportion

116 al from CAPPA could be used to convert PA of admixed meals, such as cornmeal, directly to utilizable

117 recapitulated in the indigenous ancestry of admixed mestizo individuals across the country.

118 entatives of the parental populations of the admixed Mexican American (MA) and African American (AA)

119 er, Kapingamarangi, is demonstrated to be an admixed Micronesian/Polynesian population.

120 muscle cells (SMC), extracellular matrix and admixed mononuclear leukocytes.

121 ghur samples could be challenging due to the admixed nature of the population.

122 Due to their often aneuploid nature and admixed normal tissue, heterozygous variants found in pr

123 ginal platform deposits are produced through admixing of aragonite-rich sediments, which have relativ

124 Population heterogeneity through admixing of different founder populations can produce sp

125 emperature fluids (<200 degrees C) formed by admixing of seawater, however, are invariably enriched i

126 Admixing of stellar-derived (26)Al to the protoplanetary

127 length among individuals, as well as by the admixing of telomeres inherited from affected parents wi

128 neuropathological lesions in 1,092 Brazilian admixed older adults, their correlation with cognitive a

129 ests across different population structures (admixed or non-admixed) and relatedness (related or inde

130 ations, we infer that Spanish teosinte is of admixed origin, most likely involving Zea mays ssp. mexi

131 the parental ethnicities contributing to the admixed population and (b) an understanding of the exten

132 Results for an admixed population and a phenotype strongly confounded w

133 ions, the genetic drift that occurred to the admixed population and each parental population during t

134 ence; and (7) when samples are drawn from an admixed population and one of its parent populations, th

135 um (LD) between binary markers in a recently admixed population and use a generalized least-squares m

136 enetic substructure of a unique and recently admixed population arising approximately 350 years ago a

137 enetic diversity, a sign of an older or more admixed population but not of a long-term isolate.

138 ect selection on the marker locus within the admixed population due to covariance with the trait valu

139 Our method is applicable to an admixed population from an arbitrary number of ancestral

140 ypes give rise to both the ancestral and the admixed population haplotypes, we employ an infinite hid

141 ribes both the ancestral populations and the admixed population jointly in a unified framework.

142 Puerto Ricans, an admixed population of African, European, and Native Amer

143 rgence of formally recognized breeds from an admixed population of working sheepdogs.

144 compare their utility in the case where the admixed population results from the intermating between

145 roach efficiently captures both discrete and admixed population structures.

146 Color variation in an admixed population suggests that this light Sand Hills p

147 detect selection using individuals from the admixed population than from the nonadmixed population,

148 selection using individuals sampled from the admixed population than from the nonadmixed population.

149 e define the genetic structure of a uniquely admixed population that holds great potential to advance

150 parameters when using samples drawn from the admixed population under certain conditions.

151 estry-specific allele frequencies within the admixed population under study, allowing for variation b

152 Latinas are an admixed population with most of their genetic ancestry f

153 For an admixed population, an important question is how much ge

154 a genome-wide association study (GWAS) of an admixed population, such as Hispanic Americans, ancestry

155 We hypothesized that, in this admixed population, the association between SES and asth

156 en genotypes and local ancestries on a 3-way admixed population, when the phase of each admixed indiv

157 etween mean fitness of immigrants and in the admixed population.

158 local genetic ancestry of individuals in an admixed population.

159 lation and further extend it to generate the admixed population.

160 vious cardiovascular event) and 1 study with admixed population.

161 d's feral chickens are a highly variable and admixed population.

162 nd Asia rather than settlement by an already admixed population.

163 stry analysis of genotype data from recently admixed populations (e.g. Latinos, African Americans) pr

164 ure, but the performance of these methods in admixed populations (such as African Americans) has not

165 satellite markers in 249 individuals from 13 admixed populations across Latin America.

166 led type I error rates, even when applied to admixed populations and populations with substructure.

167 Genetic association studies in admixed populations are underrepresented in the genomics

168 New World admixed populations are unique in that they represent th

169 dmix'em is designed to simulate selection in admixed populations but can also be used as a general po

170 estimate h(2) from unrelated individuals in admixed populations by first estimating the heritability

171 We show how data from unadmixed and admixed populations can be combined to estimate these an

172 nd found that genome-wide statistics vary in admixed populations even once ancestry proportions have

173 he Human Genome Diversity Panel and recently admixed populations from the 1000 Genomes Project.

174 Admixed populations have been used for inferring migrati

175 periods of gene flow shaped the diversity of admixed populations in the Americas-70% of the European

176 ariation remains to be discovered in African-admixed populations in the Americas.

177 Hence, researchers who study admixed populations in which AIMs are not available can

178 Admixture mapping based on recently admixed populations is a powerful method to detect disea

179 The extent of recent selection in admixed populations is currently an unresolved question.

180 ization of the genetic variation of recently admixed populations may reveal historical population eve

181 Admixed populations offer a unique opportunity for mappi

182 Association studies among admixed populations pose many challenges including confo

183 erred map with high-resolution maps from non-admixed populations provides evidence of fine-scale diff

184 ssociation studies, particularly in recently admixed populations such as African Americans.

185 Genetically admixed populations that speak creole languages show hig

186 e it possible to apply AM approaches in many admixed populations throughout the Americas.

187 roach that exploits the genomic structure of admixed populations to date and characterize historical

188 mapping approach uses samples from recently admixed populations to detect susceptibility loci at whi

189 support the advantages of analyzing African-admixed populations to discover new genes influencing sk

190 stry (LEA) using Local Ancestry inference in adMixed Populations using Linkage Disequilibrium method

191 te the performance of tests of neutrality in admixed populations using plausible demographic models f

192 hen inferring the locus-specific ancestry in admixed populations where the ancestral populations are

193 asthma-associated locus that is relevant to admixed populations with African ancestry and highlight

194 llows for rapid and realistic simulations of admixed populations with selection.

195 hods perform very well for both discrete and admixed populations with subject outliers.

196 d a novel approach (aMAP, ancestry of Modern Admixed Populations) for inferring local phased ancestry

197 se a method, REAP (relatedness estimation in admixed populations), for robust estimation of identity

198 roduce a new method, LAMP (Local Ancestry in adMixed Populations), which infers the ancestry of each

199 association studies, association studies in admixed populations, and homozygosity mapping studies.

200 mbination rates, inferring local ancestry in admixed populations, and importance sampling of coalesce

201 This approach, especially in admixed populations, has the potential to produce mislea

202 ference of ancestral information in recently admixed populations, in which every individual is compos

203 is not significant in other heterogeneous or admixed populations, or in fetal genotype analysis.Popul

204 discrete and admixed cases, we show that in admixed populations, spurious associations are less seve

205 correlates with lighter skin pigmentation in admixed populations, suggesting a key role for the SLC24

206 to provide a diverse genome map of different admixed populations, which can be used for future pharma

207 nstrate the methods by using data from three admixed populations--African American, African Caribbean

208 ilable) and women of heterogeneous origin or admixed populations.

209 he difficulty in replicating associations in admixed populations.

210 d identifying tracts of distinct ancestry in admixed populations.

211 ng probabilities and kinship coefficients in admixed populations.

212 likely exists, e.g., samples collected from admixed populations.

213 or performing genetic association studies in admixed populations.

214 nformative markers for assessing ancestry in admixed populations.

215 l ancestry in genetic association studies of admixed populations.

216 ure population genetic studies of additional admixed populations.

217 of locus-specific ancestry, when applied to admixed populations.

218 the divergence time and migration history of admixed populations.

219 targeting influential genetic parameters in admixed populations.

220 netic architecture of quantitative traits in admixed populations.

221 lation stratification observed in studies of admixed populations.

222 between allele frequencies in unadmixed and admixed populations.

223 of candidate genes and analyses of recently admixed populations.

224 on genetic markers sampled from parental and admixed populations.

225 dividual genotyping in both the parental and admixed populations.

226 ontribute to complex diseases in genetically admixed populations.

227 orical structure in the ancestry of American admixed populations.

228 tical difference: (i) association studies in admixed populations; (ii) association studies in presenc

229 from a chromatographic column when hosts are admixed postcolumn.

230 n that sex is costly and typically serves to admix preexisting genetic diversity from genetically div

231 distribution of ancestry in the genetically admixed Puerto Ricans.

232 aques, the effects of a 500-fold range of an admixed recombinant modified vaccinia Ankara (MVA) expre

233 Admixed recruited skin macrophages enhanced transplanted

234 the influence of sleep patterns in a highly admixed rural population with a conservative lifestyle.

235 spin-state change from an S = (5)/(2) or an admixed S = (3)/(2),(5)/(2) state at high temperatures (

236 etic cluster was possible for a historically admixed sample from southern India.

237 RFMix is capable of learning from the admixed samples themselves to boost performance and auto

238 proposed method by simulation under various admixing scenarios and present empirical analysis result

239 inciple--applicable to both the discrete and admixed settings as well as to spatial populations--give

240 dian sources over U.S.-derived lead, with an admixed signature typical of Chinese anthropogenic lead

241 ci in the 1982 Pelotas Birth Cohort Study of admixed Southern Brazilians, the COGENT-BP study of Afri

242 P.t. jacksoni tigers) and determined 52 had admixed subspecies origins.

243 atory cell phenotype responses in allogeneic admixed T cells (>4.8 fold; P < 0.05).

244 -ethylene dimethacrylate) monolith by simply admixing them in the polymerization mixture followed by

245 isolation of primary bone marrow (BM) cells, admixing them with packaging cells producing a Myc-encod

246 eakers migrated to and through the mainland, admixing there before continuing to western Indonesia.

247 An intercalating dye is admixed to label the amplicons; they are detected using

248 D-mannitol was admixed to MAC at 5, 10 and 20 wt% D-mannitol per total

249 Diet-admix treatment of apoE-KO mice with myriocin in Western

250 In addition, we developed a robust admixed tumor model consisting of CD30(+) and CD30(-) ca

251 ass fractionation can be corrected for using admixed U of known isotopic composition.

252 but the genetic determinants of CRP in these admixed United States minority populations are largely u

253 ous study designs, including homogeneous and admixed unrelated-subject and family as well as mixtures

254 find that these enigmatic canids are highly admixed varieties derived from gray wolves and coyotes,

255 evealed that extant mainland populations (i) admixed widely irrespective of ancestry, although admixt

256 the EDC-activated anti-HFA antibody (Ab) was admixed with 1% (v/v) 3-aminopropyltriethoxysilane (APTE

257 y cycle, and 5 patients received the vaccine admixed with 150 microg granulocyte macrophage-colony-st

258 ze of four) to receive rindopepimut (500 mug admixed with 150 mug GM-CSF) or control (100 mug keyhole

259 cipients that received 500 allogeneic islets admixed with 5 x 10(5) - 7 x 10(5) Tregssurvived 83.6 +/

260 CRD mice received a diet admixed with 6.6 or 60 mg/kg of the potent and selective

261 omposed of fascicles of bland myofibroblasts admixed with a prominent inflammatory component.

262 at ambient temperature to give the borole 9 admixed with a small amount of its thermal follow-up pro

263 ice immunized with the epitope-based vaccine admixed with a synthetic oligodeoxynucleotide adjuvant o

264 urine GM-CSF as an adjuvant; 2) MUC1 peptide admixed with adjuvant SB-AS2; and 3) MUC1 peptide-pulsed

265 le out-of-Africa dispersal, and subsequently admixed with archaic populations.

266 CSF-producing bystander cell line (B78H1-GM) admixed with autologous tumor, we assessed the impact of

267 is low-penetrance line, 3% of the genome was admixed with BALB alleles, suggesting a remote contamina

268 shed from primary and metastatic cancers are admixed with blood components and are thus rare, making

269 unt for partial voxel components--myocardium admixed with blood in a single voxel.

270 Nasal application of Protollin or Protollin admixed with BPEx was sufficient to inhibit allergic low

271 ry administrations of Protollin or Protollin admixed with BPEx, followed by consecutive daily BPEx ch

272 Graft experiments showed that CSCs admixed with CAFs produced prostatic glandular structure

273 nated with irradiated autologous tumor cells admixed with Calmette-Guerin bacillus.

274 lls under H2O2-induced oxidative stress when admixed with CAR-CAT T cells.

275 halosporolide E (which is typically obtained admixed with cephalosporolide F) was accomplished.

276 e show that most modern wild rice is heavily admixed with domesticated rice through both pollen- and

277 used to show that purified beta4+ adult AECs admixed with E14.5 lung single-cell suspensions and impl

278 ostimulatory (CpG) oligodeoxyribonucleotides admixed with either Alhydrogel or ISCOMATRIX adjuvant.

279 In some cases, stromal hyperplasia was admixed with epithelial metaplasia, sometimes with kerat

280 composed of more than 90% necrotic material admixed with few macrophages and viable cells at their o

281 nsisted of irradiated autologous tumor cells admixed with GM-CSF-secreting bystander cells.

282 erapy consisted of autologous leukemia cells admixed with granulocyte-macrophage colony-stimulating f

283 l T-helper epitopes of the HER-2/neu protein admixed with granulocyte-macrophage colony-stimulating f

284 r lymphoma (FL), malignant B cells are found admixed with heterogeneous lymphoid-like stromal cells w

285 Multiple myeloma (MM) cell lines admixed with human bone marrow (BM) or peripheral blood

286 lties in accounting for highly soluble salts admixed with less soluble salts, the lack of clay minera

287 fluence the above processes and that resides admixed with microbial ligands for innate receptors gene

288 nd safety of three vaccines: 1) MUC1 peptide admixed with murine GM-CSF as an adjuvant; 2) MUC1 pepti

289 Administration of appropriate antigens admixed with or coupled to these toxins by oral, intrana

290 They purportedly admixed with or displaced indigenous Dravidic-speaking p

291 all-cell carcinoma of the urinary bladder is admixed with other histological types of bladder carcino

292 hyrins with the intermediate spin S = 3/2 or admixed with S = 5/2 or 1/2 are models for a number of h

293 tumor vaccine consisting of leukemic blasts admixed with skin fibroblasts transduced with adenoviral

294 ns of iron-labeled mesenchymal stromal cells admixed with tissue dye were performed in previously inf

295 When admixed with transgenic APC, activated T lymphocytes pro

296 Furthermore, when admixed with tumor cells, CD11b(+)Gr-1(+) cells from tum

297 sfected with green fluorescent protein (GFP) admixed with wild-type HeLa cells at ratios of 1:10(4) t

298 an populations are descended from, or highly admixed with, members of a subsequent migration event.

299 oduced into South America, their descendents admixing with previously introduced European bees, givin

300 Unlike CE-EPCs, CD14(+) leukocytes admixed within tumors did not generate vWF-positive bloo