ライフサイエンスコーパス: admixed population

1 nd Asia rather than settlement by an already admixed population.

2 etween mean fitness of immigrants and in the admixed population.

3 local genetic ancestry of individuals in an admixed population.

4 vious cardiovascular event) and 1 study with admixed population.

5 lation and further extend it to generate the admixed population.

6 d's feral chickens are a highly variable and admixed population.

7 erefore could be a useful test of linkage in admixed populations.

8 ontribute to complex diseases in genetically admixed populations.

9 orical structure in the ancestry of American admixed populations.

10 ilable) and women of heterogeneous origin or admixed populations.

11 he difficulty in replicating associations in admixed populations.

12 d identifying tracts of distinct ancestry in admixed populations.

13 ng probabilities and kinship coefficients in admixed populations.

14 likely exists, e.g., samples collected from admixed populations.

15 or performing genetic association studies in admixed populations.

16 nformative markers for assessing ancestry in admixed populations.

17 l ancestry in genetic association studies of admixed populations.

18 ure population genetic studies of additional admixed populations.

19 of locus-specific ancestry, when applied to admixed populations.

20 the divergence time and migration history of admixed populations.

21 netic architecture of quantitative traits in admixed populations.

22 targeting influential genetic parameters in admixed populations.

23 lation stratification observed in studies of admixed populations.

24 between allele frequencies in unadmixed and admixed populations.

25 of candidate genes and analyses of recently admixed populations.

26 on genetic markers sampled from parental and admixed populations.

27 dividual genotyping in both the parental and admixed populations.

28 satellite markers in 249 individuals from 13 admixed populations across Latin America.

29 nstrate the methods by using data from three admixed populations--African American, African Caribbean

30 For an admixed population, an important question is how much ge

31 the parental ethnicities contributing to the admixed population and (b) an understanding of the exten

32 Results for an admixed population and a phenotype strongly confounded w

33 ions, the genetic drift that occurred to the admixed population and each parental population during t

34 of marker allele frequencies in the current, admixed population and in one of the founding population

35 ence; and (7) when samples are drawn from an admixed population and one of its parent populations, th

36 um (LD) between binary markers in a recently admixed population and use a generalized least-squares m

37 led type I error rates, even when applied to admixed populations and populations with substructure.

38 two founding populations are assumed for the admixed population, and have found that if there is rand

39 association studies, association studies in admixed populations, and homozygosity mapping studies.

40 mbination rates, inferring local ancestry in admixed populations, and importance sampling of coalesce

41 Genetic association studies in admixed populations are underrepresented in the genomics

42 New World admixed populations are unique in that they represent th

43 enetic substructure of a unique and recently admixed population arising approximately 350 years ago a

44 tween FY and AT3 emphasize the importance of admixed populations as a useful resource for mapping tra

45 enetic diversity, a sign of an older or more admixed population but not of a long-term isolate.

46 dmix'em is designed to simulate selection in admixed populations but can also be used as a general po

47 estimate h(2) from unrelated individuals in admixed populations by first estimating the heritability

48 We show how data from unadmixed and admixed populations can be combined to estimate these an

49 Simulations based on an admixed population demonstrate good operating characteri

50 ect selection on the marker locus within the admixed population due to covariance with the trait valu

51 stry analysis of genotype data from recently admixed populations (e.g. Latinos, African Americans) pr

52 nd found that genome-wide statistics vary in admixed populations even once ancestry proportions have

53 d a novel approach (aMAP, ancestry of Modern Admixed Populations) for inferring local phased ancestry

54 se a method, REAP (relatedness estimation in admixed populations), for robust estimation of identity

55 Our method is applicable to an admixed population from an arbitrary number of ancestral

56 he Human Genome Diversity Panel and recently admixed populations from the 1000 Genomes Project.

57 ypes give rise to both the ancestral and the admixed population haplotypes, we employ an infinite hid

58 This approach, especially in admixed populations, has the potential to produce mislea

59 Admixed populations have been used for inferring migrati

60 tical difference: (i) association studies in admixed populations; (ii) association studies in presenc

61 periods of gene flow shaped the diversity of admixed populations in the Americas-70% of the European

62 ariation remains to be discovered in African-admixed populations in the Americas.

63 Hence, researchers who study admixed populations in which AIMs are not available can

64 ference of ancestral information in recently admixed populations, in which every individual is compos

65 risk by linkage-disequilibrium mapping in an admixed population is not critically dependent on assump

66 Admixture mapping based on recently admixed populations is a powerful method to detect disea

67 The extent of recent selection in admixed populations is currently an unresolved question.

68 ribes both the ancestral populations and the admixed population jointly in a unified framework.

69 ization of the genetic variation of recently admixed populations may reveal historical population eve

70 Puerto Ricans, an admixed population of African, European, and Native Amer

71 rgence of formally recognized breeds from an admixed population of working sheepdogs.

72 stions using skin reconstitution assays with admixed populations of genetically labeled, cultured ker

73 Admixed populations offer a unique opportunity for mappi

74 is not significant in other heterogeneous or admixed populations, or in fetal genotype analysis.Popul

75 Association studies among admixed populations pose many challenges including confo

76 erred map with high-resolution maps from non-admixed populations provides evidence of fine-scale diff

77 compare their utility in the case where the admixed population results from the intermating between

78 discrete and admixed cases, we show that in admixed populations, spurious associations are less seve

79 roach efficiently captures both discrete and admixed population structures.

80 ssociation studies, particularly in recently admixed populations such as African Americans.

81 ure, but the performance of these methods in admixed populations (such as African Americans) has not

82 a genome-wide association study (GWAS) of an admixed population, such as Hispanic Americans, ancestry

83 correlates with lighter skin pigmentation in admixed populations, suggesting a key role for the SLC24

84 Color variation in an admixed population suggests that this light Sand Hills p

85 detect selection using individuals from the admixed population than from the nonadmixed population,

86 selection using individuals sampled from the admixed population than from the nonadmixed population.

87 e define the genetic structure of a uniquely admixed population that holds great potential to advance

88 Genetically admixed populations that speak creole languages show hig

89 We hypothesized that, in this admixed population, the association between SES and asth

90 found that if there is random mating in the admixed population, then typically there is a collapsing

91 ation about the founding populations and the admixed population, thereby collapsing the marker into o

92 e it possible to apply AM approaches in many admixed populations throughout the Americas.

93 roach that exploits the genomic structure of admixed populations to date and characterize historical

94 mapping approach uses samples from recently admixed populations to detect susceptibility loci at whi

95 support the advantages of analyzing African-admixed populations to discover new genes influencing sk

96 parameters when using samples drawn from the admixed population under certain conditions.

97 estry-specific allele frequencies within the admixed population under study, allowing for variation b

98 stry (LEA) using Local Ancestry inference in adMixed Populations using Linkage Disequilibrium method

99 te the performance of tests of neutrality in admixed populations using plausible demographic models f

100 en genotypes and local ancestries on a 3-way admixed population, when the phase of each admixed indiv

101 hen inferring the locus-specific ancestry in admixed populations where the ancestral populations are

102 roduce a new method, LAMP (Local Ancestry in adMixed Populations), which infers the ancestry of each

103 to provide a diverse genome map of different admixed populations, which can be used for future pharma

104 Latinas are an admixed population with most of their genetic ancestry f

105 asthma-associated locus that is relevant to admixed populations with African ancestry and highlight

106 llows for rapid and realistic simulations of admixed populations with selection.

107 hods perform very well for both discrete and admixed populations with subject outliers.