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2 onal region and alternative splicing, and of adoptively administering them to patients with relapsed
3 MOG-specific CD8 T cells could also suppress adoptively induced disease using wild-type MOG35-55-spec
4 proach for ovarian and other tumors in which adoptively infused gammadelta T cells are targeted using
5 fector memory T (Tem) cells were transferred adoptively to allergen-sensitized animals before allerge
7 Using allotype markers, it is possible to adoptively transfer memory B cells into a naive mouse an
9 r protection of nude mice was achieved using adoptively transferred 1.0 and 0.1 million, but not 0.01
11 man islet cells under the kidney capsule and adoptively transferred 5 x 10(6) splenocytes from 6-week
12 mation and goblet cell hyperplasia driven by adoptively transferred Ag-specific CD4(+) Th2 cells.
13 rejection and augmented the proliferation of adoptively transferred alloantigen-specific CD4(+) T cel
17 l was carried out to evaluate the ability of adoptively transferred autologous T cells transduced wit
18 o 70% of patients with melanoma who received adoptively transferred autologous tumor-infiltrating lym
20 nic B cell numbers, survival and function of adoptively transferred B cells, Th cell function, and de
24 ion profiles of other chemokine receptors of adoptively transferred BLT1(+)/(+) and BLT1(-)/(-) CD8(+
26 ptor CCR2; 2) compared with CCR2(+/+) cells, adoptively transferred CCR2(-/-) bone marrow-derived DCs
30 28 also enhanced the suppressive capacity of adoptively transferred CD4(+) nTregs by increasing the s
35 , and specific cellular interactions between adoptively transferred CD8 T cells and specific CNS cell
36 -infiltrating myeloid cells is important for adoptively transferred CD8(+) cytotoxic T cells to destr
37 intravascular adhesion and extravasation of adoptively transferred CD8(+) effectors that is indispen
38 imal expansion, trafficking, and function of adoptively transferred CD8(+) T cells are parameters tha
42 ipient mice supported the rapid expansion of adoptively transferred CD8+ T cells against melanoma.
44 d humans correlates with both a high dose of adoptively transferred cells and cells with a minimally
47 ith or without cotransplanted kidneys and/or adoptively transferred cells from long-term tolerant (LT
48 wine received class I mismatched kidney with adoptively transferred cells from LTT SLA(dd) recipients
49 in the spleen (where a major portion of the adoptively transferred cells homed) and in the eyes, whe
50 t the lifespan, safety, and functionality of adoptively transferred cells in the presence of autologo
52 or cells significantly reduced the number of adoptively transferred cells that entered into the perit
53 icide genes can install a 'safety switch' on adoptively transferred cells to allow ablation if necess
54 T-cell expansion improved the persistence of adoptively transferred cells, reduced tumor growth, and
59 f T cell tolerogenesis, we further show that adoptively transferred central but not effector memory T
60 targeted BCR transgenic mice, we showed that adoptively transferred cFLIP-deficient follicular B cell
61 e clinical efficacy and anatomic location of adoptively transferred chemokine receptor-deficient CD4(
63 tive optical control of Ca(2+) signalling in adoptively transferred CTLs enhances T cell activation a
67 Strikingly, we found that the activity of adoptively transferred DGKzeta(-/-) T cells relied partl
68 at this single SNP developed spontaneous or adoptively transferred diabetes at comparable rates and
69 we expanded CD98-null T cells in vitro, they adoptively transferred diabetes, establishing that impai
70 ressing the diabetogenic AI4 T-cell receptor adoptively transferred disease to otherwise unmanipulate
72 curs in the presence of rapamycin or whether adoptively transferred donor Th9 cells would augment or
75 engineered T cells to overexpress TRAIL and adoptively transferred donor-type unsorted TRAIL+ T cell
77 d that persistence and antitumor activity of adoptively transferred effector T cells deficient in TGF
78 s to generate the damaging Ab repertoire, we adoptively transferred either MZBs or follicular B cells
79 k macrophage dynamics in dysferlinopathy, we adoptively transferred enhanced green fluorescent protei
80 ted in the worsening of actively induced and adoptively transferred experimental autoimmune encephalo
87 ivo microscopy corroborated proliferation of adoptively transferred hematopoietic progenitors in the
89 CID/IL2Rg(null) mice, but the persistence of adoptively transferred HSPC-NK cells was not affected.
92 cial pathogenic role played by IL-21 in T1D, adoptively transferred IFN-gamma-deficient CpG-proBs did
95 revent graft-versus-host disease (GVHD) when adoptively transferred in murine models of hematopoietic
98 bakeri-infected mice prevented colitis when adoptively transferred into a murine model of inflammato
100 s plus B-cell-depleted wild-type splenocytes adoptively transferred into B-cell-deficient muMT mice r
101 CD8 T effector cells (Tc17) from OT-1 mice, adoptively transferred into B16-OVA tumor-bearing mice,
102 el was established whereby DsRedOTI-Tc cells adoptively transferred into B6 mice bearing either a ova
104 cs of CD4-mediated help, CD4(+) T cells were adoptively transferred into CD4-deficient mice at variou
105 Monoclonal T. gondii-specific CD8 T cells adoptively transferred into coinfected mice recapitulate
107 ed with cytokines (GM-CSF, IL-4, IL-33) were adoptively transferred into eosinophil-deficient recipie
108 when FcgammaR(+/+) dendritic cells (DCs) are adoptively transferred into FcgammaR(-/-) mice, uptake a
111 ly, neutrophils generated in this way can be adoptively transferred into live animals and tracked dur
115 om unstressed control mice were isolated and adoptively transferred into naive lymphopenic Rag2(-/-)
120 hermore, p47(phox-/-) DCs pulsed with Lm and adoptively transferred into naive WT mice elicited Ab ti
122 ts with undetectable plasma viral loads were adoptively transferred into NOD.Cg-Prkdc(scid)Il2rg(tm1W
123 ogenic than their wild-type counterpart when adoptively transferred into NOD.Rag1(-/-) recipients, ev
125 1(-) thymocytes from Rag1((-)/(-)) mice were adoptively transferred into Rag1((-)/(-))Ly5.1 congenic
126 d capable of inducing stromal keratitis when adoptively transferred into Rag1(-/-) mice, with 95% of
127 of miR-15b/16 in conventional CD4(+) T cells adoptively transferred into Rag2(-/-) mice increased the
128 , which could by themselves mediate AHR when adoptively transferred into Rag2(-/-); Il2rg(-/-) mice t
129 genic cells specific to hen egg lysozyme are adoptively transferred into recipients that express hen
130 by the spontaneous proliferation of T cells adoptively transferred into specific pathogen-free (SPF)
132 ulation responsible, primed CD8 T cells were adoptively transferred into tumor-bearing immunocompromi
133 wild-type counterparts, C5aR(-/-) mast cells adoptively transferred into W/Wv mice were not competent
139 t of infection from a high-dose inoculum, we adoptively transferred large numbers of T cells that wer
140 irect effects of Psgl-1, because Psgl-1(+/+) adoptively transferred leukocytes did not exhibit enhanc
141 roscopy of lymph node explants revealed that adoptively transferred lymphocytes accumulated at lympha
143 Fluorescent imaging analyses revealed that adoptively transferred M2r macrophages specifically home
145 d in C57BL/6J-Kit(W-sh/W-sh) mice containing adoptively transferred mast cells that were either wild
149 was assessed by quantifying proliferation of adoptively transferred monoclonal T-cell receptor transg
150 experiments revealed that the recruitment of adoptively transferred monocytes and neutrophils to the
151 sed expression within primary tumors, as the adoptively transferred MSC develop carcinoma-associated
152 x virus-thymidine kinase (TK) gene] when the adoptively transferred MSC developed endothelial-like ch
159 l population was successfully outcompeted by adoptively transferred naive T cells, and (iii) demonstr
160 e immune milieu, CTX preconditioning allowed adoptively transferred naive tumor-specific CD4+ T cells
164 o optimize the in vivo cytokine milieu where adoptively transferred NK cells compete with other lymph
165 poxia, and transgenic expression of IL-15 in adoptively transferred NKT cells dramatically enhanced t
167 confirmed by experiments in which MBCs were adoptively transferred or depleted before secondary chal
168 le, we show that CD154 expression identifies adoptively transferred or endogenous Ag-specific CD4(+)
171 gely abrogated the proliferative response of adoptively transferred OVA peptide-specific-transgenic C
173 jection, we used a transgenic model in which adoptively transferred ovalbumin (OVA)-specific cytotoxi
178 y, we evaluated the antileukemia activity of adoptively transferred polyclonal cancer antigen-reactiv
179 e mouse spleen and promoted the migration of adoptively transferred pre-activated B cells to the T/B
180 knock-in mice (termed HKIR) were relieved in adoptively transferred recipients in the presence of Sle
184 tion, and clonal expansion of endogenous and adoptively transferred Salmonella-specific CD4 T cells w
187 pled to inadequate cardiac commitment of the adoptively transferred stem cells compromises the improv
189 d manner and lends itself to manipulation of adoptively transferred T cells and characterizing specif
190 results in increased antitumor immunity when adoptively transferred T cells are presensitized, but de
192 is shown that effector cytokines secreted by adoptively transferred T cells expressing a chimeric Ag
193 F/VEGFR-2 axis can increase extravasation of adoptively transferred T cells into the tumor and improv
194 studies also demonstrate that persistence of adoptively transferred T cells is associated with therap
197 esponse and may help prevent inactivation of adoptively transferred T cells thereby improving therape
198 cell surface marker for in vivo tracking of adoptively transferred T cells using both flow cytometry
200 e control of cytotoxic effector functions of adoptively transferred T cells with outstanding spatial
201 hich host tumor Ag cross-presentation primes adoptively transferred T cells, which remain functional
220 tide injection, in vivo Helios expression in adoptively transferred TCR transgenic T cells was more r
221 activation, proliferation, and expansion of adoptively transferred TEa cells in an Ag-specific manne
222 In this study, we show that activation of adoptively transferred Th cells during primary influenza
225 h2-, or IL-17-producing CD4(+) T cells, were adoptively transferred to APP/PS1 mice at 6 to 7 mo of a
226 ) T cells from Il17a fate-mapping mice, were adoptively transferred to assess their persistence in ge
227 normal-mouse infection site tissue Mphi were adoptively transferred to burned mice at the MRSA infect
229 uman peripheral blood mononuclear cells were adoptively transferred to immunodeficient mice lacking a
230 endritic cells cultured with SA-IVIg or IVIg adoptively transferred to mice before OVA challenge indu
231 purified graft-reactive CD4CD25 T cells were adoptively transferred to mice-bearing skin allograft.
233 In gain-of-function experiments, B-1a cells, adoptively transferred to muMT mice with EAE, restored t
236 erior activity against tuberculosis could be adoptively transferred to naive, syngeneic mice by CD4(+
240 have demonstrated impressive responses when adoptively transferred to patients with advanced chronic
242 cells were sorted by flow cytometry and were adoptively transferred to recipient mice through tail ve
243 cells specific to hen egg lysozyme (HEL) are adoptively transferred to recipients and induce inflamma
244 against EAE when A2AAR(-/-) lymphocytes were adoptively transferred to T cell-deficient A2AAR(+/+) mi
245 yte-restricted adiponectin gene promoter was adoptively transferred to wild-type recipient mice.
246 have evolved from a hypothetical mediator of adoptively transferred tolerance to a well-defined popul
248 PC survival niches and their functioning, we adoptively transferred traceable Blimp-1-(GFP) PCs into
251 s) have potent anti-inflammatory effects, we adoptively transferred Tregs into infected C57BL/6 and R
252 ously published studies of ex vivo-activated adoptively transferred tumor antigen-specific CD8+ T cel
253 tion and expansion and/or persistence of the adoptively transferred tumor antigen-specific T cells in
255 the survival and effector differentiation of adoptively transferred tumor-reactive CD8(+) T-cells.
256 t for survival and proper differentiation of adoptively transferred tumor-specific CD4(+) T cells.
259 ring effector phase of chronic infection, we adoptively transferred virus-specific day 8 effector CD8
261 has demonstrated the safety and efficacy of adoptively transferred virus-specific T cells for the pr
262 miquimod-treated skin of CCR6(-/-) mice, but adoptively transferred wild-type (CCR6(+/+)) gammadeltaT
265 cell function was investigated in Rag1 mice adoptively transferred with alloprimed IgG1 B cells.
266 In RAG(-/-) recipients of skin allografts adoptively transferred with CD4(+) T cells, we show that
267 ficantly reduced in wild-type recipient mice adoptively transferred with DNFB immunity generated in P
268 In addition, the recipient mice that are adoptively transferred with JKAP-knockout T cells show e
269 xaggerated response in DeltaLC mice could be adoptively transferred with liver CD49a(+) NK cells.
271 nted onto C57BL/6-RAG-1-deficient recipients adoptively transferred with purified sorted CD4CD25 T ce
272 equently, STING(-/-) mice, or wild-type mice adoptively transferred with STING(-/-) bone marrow, are
277 However, Nfil3/Rag1 double-knockout mice adoptively transferred with wild-type CD4(+) T cells dev
279 ID mice but did occur in SCID mice that were adoptively transferred with wild-type T cells, indicatin
281 in part due to increased M2 macrophages, we adoptively transferred wt macrophages into Cd14(-/-) mic
282 ce were almost completely protected from the adoptively transferred, aggressive form of T1D caused by
284 tantly, induced genetic deletion of Orai1 in adoptively transferred, MOG-specific T cells was able to
285 allergic airway inflammation (AAI) driven by adoptively transferred, traceable ovalbumin-experienced
286 turation, a significantly higher fraction of adoptively transferred, tumor-reactive (reporter) CD8(+)
287 cells exclusively generated B-1a cells when adoptively transferred, whereas sorted CD93(+)IgM(+)CD5(
289 ent T-cell alterations, could be restored by adoptively transferring CCR8-expressing monocytes/macrop
290 cDC-mediated induction pulmonary allergy by adoptively transferring house dust mite (HDM)-pulsed bon
291 nd that providing an accelerated response by adoptively transferring large numbers of antiviral T cel
292 se inhibitor Nor-NOHA but were reproduced by adoptively transferring MDSC or injecting arginase 1 to
293 ion in a genetically deficient strain and by adoptively transferring NK cells into NK-deficient mice.
294 or effective antitumor immunity was shown by adoptively transferring purified CD27(low)KLRG1(+) NK ce
295 progressive depigmentation was evaluated by adoptively transferring purified Treg or using rapamycin
298 f regulatory T (Treg) cells was evaluated by adoptively transferring Treg cells from milk EPIT-treate
299 CD4 depletion was completely neutralized by adoptively transferring tumor-specific Foxp3(+) T cells.
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