ライフサイエンスコーパス: adrenal cortex

1 5 may have tumor suppressor functions in the adrenal cortex.

2 nce of optimal steroidogenic capacity in the adrenal cortex.

3 -induced release of corticosteroids from the adrenal cortex.

4 deglycosylation of DLIF isolated from bovine adrenal cortex.

5 n or by autonomous cortisol release from the adrenal cortex.

6 me is caused by tumors or hyperplasia of the adrenal cortex.

7 n that leads to release of cortisol from the adrenal cortex.

8 dogenic cells in the zona fasciculata of the adrenal cortex.

9 alamic control of the anterior pituitary and adrenal cortex.

10 a is an aggressive, lethal malignancy of the adrenal cortex.

11 ple organs, including the testis, ovary, and adrenal cortex.

12 chain fatty acids, particularly in brain and adrenal cortex.

13 GP prior to the separation between gonad and adrenal cortex.

14 g in the release of glucocorticoids from the adrenal cortex.

15 timulation of aldosterone secretion from the adrenal cortex.

16 roidogenic tissues, including the gonads and adrenal cortex.

17 of several steroidogenic genes in the human adrenal cortex.

18 ase that is upregulated during growth of the adrenal cortex.

19 marily expressed in the liver, intestine and adrenal cortex.

20 ly modified and was similar to normal bovine adrenal cortex.

21 of the bovine adrenodoxin (Adx) gene in the adrenal cortex.

22 system, which results in hyperplasia of the adrenal cortex.

23 immunohistochemistry to the liver and to the adrenal cortex.

24 pathway different from that existing in the adrenal cortex.

25 elevated glucocorticoid concentrations after adrenal cortex activation; and e) release of bacterial p

26 lished the anti-apoptotic action of serum in adrenal cortex adenocarcinoma (SW13) cells.

27 In the human adrenal cortex, adrenocorticotropin (ACTH) activates CYP

28 It is produced by the adrenal cortex after angiotensin II activation of angiot

29 that PKA 1) induces metabolic changes in the adrenal cortex and 2) phosphorylates CtBP proteins, part

30 g in increased steroidogenic activity in the adrenal cortex and an elevation of cortisol levels in th

31 udes the release of glucocorticoids from the adrenal cortex and catecholamines from the adrenal medul

32 It has been proposed that the mammalian adrenal cortex and gonad are derived from the same primo

33 uclear receptor selectively expressed in the adrenal cortex and gonads, where it mediates the hormona

34 mice exhibited highly reduced Tspo levels in adrenal cortex and gonads.

35 athway--in both embryonic development of the adrenal cortex and in maintenance of the adult organ.

36 pituitary-adrenal (LHPA) axis, with enlarged adrenal cortex and increased glucocorticoid levels.

37 rect Sf1 expression exclusively in the fetal adrenal cortex and is bound by both Sf1 and Dax1.

38 a dual-specificity PDE that is expressed in adrenal cortex and is partially inhibited by tadalafil a

39 the expression of CYP2D16 in the guinea pig adrenal cortex and its relationship to adrenal xenobioti

40 orticoid/catecholamine) interactions in both adrenal cortex and medulla is much greater in fetal shee

41 rticosterone content and hyperplasia of both adrenal cortex and medulla.

42 ter usage of IL-18 gene and suggest that the adrenal cortex and not immune cells may be the source of

43 e adrenal gland, some of which traversed the adrenal cortex and reached the adrenal medulla.

44 ituitary, with consequent stimulation of the adrenal cortex and release of glucocorticoids critical f

45 t levels in the inner zone of the guinea pig adrenal cortex and suggest a major role for this isozyme

46 n the human stomach and, very weakly, in the adrenal cortex and the brain.

47 und, type II PtdIns 4-kinase activity of the adrenal cortex and the type III enzyme of bovine brain.

48 that depends in part on the integrity of the adrenal cortex and vagus.

49 lt adrenocortical steroidogenic cells (fetal adrenal cortex and/or the adrenal capsule).

50 otein specific to the inner zones of the rat adrenal cortex, and called inner zone antigen (IZAg), wa

51 ency that impairs cortisol production by the adrenal cortex, and can lead to sexual ambiguity in both

52 , which ultimately gives rise to the kidney, adrenal cortex, and gonad.

53 ing hsp70 (the liver, pancreas, heart, lung, adrenal cortex, and intestine).

54 67 that is produced in human islets, testis, adrenal cortex, and perhaps other endocrine tissues, but

55 ng pancreatic islets, parathyroids, thyroid, adrenal cortex, and pituitary are seen by 16 months.

56 ogenic tissues, including the testis, ovary, adrenal cortex, and placenta.

57 ally drives glucocorticoid production in the adrenal cortex, and the sympathetic-adrenal-medullary ax

58 in the locus coeruleus, inferior olive, and adrenal cortex; and decreased AT(2) receptor binding in

59 adrenal capsular cells to the differentiated adrenal cortex are not fully understood.

60 roxylase, an intracellular key enzyme of the adrenal cortex, are found in >90% of patients, but these

61 e III PI 4-kinases were isolated from bovine adrenal cortex as [3H]WT-labeled 110- and 210-kDa protei

62 nco-developmental genes present in the fetal adrenal cortex, as well as local adrenal paracrine and a

63 al alterations in the hypothalamic-pituitary-adrenal cortex axis and the sympathetic nervous system,

64 i) theca interna cells in the ovary; and (j) adrenal cortex (but not adrenal medulla).

65 y in the zona fasciculata/reticularis of the adrenal cortex, but also in the Leydig cell, kidney and

66 pha is involved in similar regulation in the adrenal cortex, but it also substantially modulates gluc

67 thus of angiotensin, and (3) stimulation of adrenal cortex by angiotensin is consistent with all the

68 ation of SF-1-dependent transcription in the adrenal cortex by signaling molecules such as protein ki

69 Aldosterone, synthesized in the adrenal cortex by the enzyme CYP11B2, induces positive s

70 A), the predominant androgen secreted by the adrenal cortex, can be converted to both potent androgen

71 tervention and induction of immunity against adrenal cortex cancer.

72 Adrenal Cortex Carcinoma (ACC) is an aggressive tumour w

73 iency of 21-hydroxylase is a disorder of the adrenal cortex characterised by cortisol deficiency, wit

74 of EG-VEGF in a responsive cell type, bovine adrenal cortex-derived endothelial (ACE) cells.

75 gene transcription, and cell cycle arrest in adrenal cortex-derived Y1 cells.

76 high levels in peripheral tissues, including adrenal cortex (E16-E21) and cochlear ganglia (E19-P3),

77 Here we report that VEGF treatment of bovine adrenal cortex endothelial cells resulted in a 5-fold in

78 Bovine adrenal cortex endothelial cells were incubated with 200

79 Finally, treatment of adrenal cortex endothelial cells with VEGF or phorbol es

80 nchiolar epithelium of the lung, myocardium, adrenal cortex, epithelium of the seminal vesicles, prox

81 in, is synthesized in mammalian placenta and adrenal cortex from cholesterol through the novel acidic

82 hways involved in the differentiation of the adrenal cortex from the adrenogonadal primordium (AGP) h

83 ed2 is required for the specification of the adrenal cortex from the AGP.

84 sis, were identified that distinguish normal adrenal cortex from tumor.

85 The tissue distribution of DAX-1 (adrenal cortex, gonads, hypothalamus, and pituitary) is

86 placenta, brain, testis, ovary, spleen, and adrenal cortex have the highest levels of expression of

87 amplified from RNA of interrenal tissue (the adrenal cortex homolog) from the southern stingray (Dasy

88 y-adrenal (HPA) axis, resulting in increased adrenal cortex hyperplasia and corticosterone production

89 20alpha-DHOPA paralleled the development of adrenal cortex hyperplasia, hypercortisolism, and spleen

90 tary and counterregulative adaptation of the adrenal cortex in abused women without major depressive

91 Cortisol, secreted in the adrenal cortex in response to stress, is an informative

92 promoting effect of high levels of LH on the adrenal cortex in the absence of ovarian tumors.

93 , theca cells of the ovary, and cells of the adrenal cortex in transgenic animals.

94 timulated SAPK activity 3-4-fold both in the adrenal cortex in vivo and in the Y1 adrenocortical cell

95 K by ACTH, ERK activity was inhibited in the adrenal cortex in vivo and in Y1 adrenal cells.

96 ybridization showed that, in contrast to the adrenal cortex, in spleen and duodenum IL-18 is primaril

97 egulation of these synthetic pathways in the adrenal cortex inner zone during acute inflammation.

98 logical control of cortisol synthesis in the adrenal cortex involves stimulation of adrenocorticotrop

99 Glucocorticoid production in the adrenal cortex is activated in response to an increase i

100 goxin-like immunoreactive factor (DLIF) from adrenal cortex is an endogenous molecule with structural

101 Steroid hormone biosynthesis in the adrenal cortex is controlled by adrenocorticotropin (ACT

102 nduced and maintained and how renewal of the adrenal cortex is ensured remain a mystery.

103 al medullae denervation, suggesting that the adrenal cortex mediates this effect.

104 Histologically, the adrenal cortex of StAR knockout mice contained florid li

105 Here we report that the patches in mosaic adrenal cortex of the mouse and rat are also fractal and

106 gh levels of glucocorticoids produced by the adrenal cortex of the stressed subject reduce neurogenes

107 Adrenal cortex physiology relies on functional zonation,

108 As distinct from the adrenal cortex, production of A, B, Aldo, 18OHdeoxycorti

109 ortical blunting resides at the level of the adrenal cortex rather than higher up the axis.

110 effects of stress and with mediation by the adrenal cortex, restraint stress evoked repeated transie

111 lysis showed that IGIF is synthesized in the adrenal cortex, specifically in the zona reticularis and

112 rom the inner zone (zona reticularis) of the adrenal cortex than from the outer zones, coinciding wit

113 osolic PtdIns 4-kinase (cPI4K) in the bovine adrenal cortex that is distinguished from previously kno

114 n a sea of the other cell type, while in the adrenal cortex the pattern is one of alternating cords o

115 In the human adrenal cortex, the peptide hormone adrenocorticotropin

116 that during organogenesis in both liver and adrenal cortex, the same basic mechanism is directed to

117 It is expressed exclusively in the outer adrenal cortex, the site of cell proliferation, and in t

118 athology, and to disorders that affected the adrenal cortex, the spinal cord, the cerebellum and the

119 In the human adrenal cortex this process may be a precursor of adrena

120 that PKA acts as a tumour suppressor in the adrenal cortex, through repression of WNT signalling.

121 steroidogenic capacity is maintained in the adrenal cortex throughout life.

122 apidly secrete catecholamines (CAs), and the adrenal cortex to release progesterone (PROG), which may

123 e from the pituitary, which then acts on the adrenal cortex to stimulate the secretion of corticoster

124 lls with nuclear p21 and p53 appeared in the adrenal cortex together with DNA damage detected by in s

125 investigate the role of beta-catenin in the adrenal cortex, we used two Sf1/Cre transgenes to inacti

126 reticularis and the zona fasciculata of the adrenal cortex, where its levels are elevated by acute s

127 Finally, mice deficient for SR-BI in the adrenal cortex, where the receptor provides lipoprotein-

128 Tumors of the adrenal cortex, whether benign or malignant, are often a

129 To investigate this, we studied the adrenal cortex, which is composed of functionally distin

130 from resistance to the action of ACTH on the adrenal cortex, which stimulates glucocorticoid producti

131 , we compared the expression of IL-18 in the adrenal cortex with that of spleen and duodenum, two oth

132 Abnormal lipid storage is evident in the adrenal cortex, with characteristic lamellar-lipid inclu