ライフサイエンスコーパス: adult neural stem cell

1 cyte emerges as a beguiling companion to the adult neural stem cell.

2 vidence suggests propensity for infection of adult neural stem cells.

3 tors are thought to regulate the activity of adult neural stem cells.

4 em into a transcriptional program activating adult neural stem cells.

5 idence suggests that it is also expressed in adult neural stem cells.

6 y activating the atypical PKC/CBP pathway in adult neural stem cells.

7 es maintain self-renewal and multipotency of adult neural stem cells.

8 al neuronal circuitry has a direct impact on adult neural stem cells.

9 hould be useful in targeting floxed genes in adult neural stem cells.

10 tin signaling in regulating proliferation of adult neural stem cells.

11 es novel insights into in vivo properties of adult neural stem cells.

12 ogenitor proliferation, and specification of adult neural stem cells.

13 ultistage process of generating neurons from adult neural stem cells.

14 umbilical vein endothelial cells, and murine adult neural stem cells.

15 w neurons is believed to be from multipotent adult neural stem cells.

16 to the proliferation and differentiation of adult neural stem cells.

17 tightly regulate the neuronal development of adult neural stem cells.

18 s in the adult brain led to the discovery of adult neural stem cells.

19 y modify the lineage that links neonatal and adult neural stem cells.

20 in IMP1, that is expressed by fetal, but not adult, neural stem cells.

21 ne that labels quiescent subventricular zone adult neural stem cells also labels a subset of endogeno

22 late proliferation and fate determination of adult neural stem cells and describe recent studies conc

23 molecular and cellular mechanisms regulating adult neural stem cells and how these cells may contribu

24 Here we show that FTO is expressed in adult neural stem cells and neurons and displays dynamic

25 a transgenic mouse line to reversibly ablate adult neural stem cells and suppress neurogenesis.

26 g hedgehog signaling is required to maintain adult neural stem cells and that their ability to self-r

27 Recent studies on adult neural stem cells and the developmental biology of

28 the generation of new neurons from a pool of adult neural stem cells and their integration into funct

29 s encompassing the birth of new neurons from adult neural stem cells and their integration into the e

30 e resulted in indelible expression of Tom in adult neural stem cells and their lineage upon tamoxifen

31 also discuss remaining questions related to adult neural stem cells and their niches, underlying reg

32 The ability to prospectively isolate adult neural stem cells and their progeny is crucial to

33 uiding the field toward better understanding adult neural stem cells and ultimately applying these pr

34 on, and material moduli from 10-10,000 Pa on adult neural stem-cell (aNSC) behavior.

35 ws us to investigate how FXR1P deficiency in adult neural stem cells (aNSCs) affects proliferation an

36 Adult neural stem cells (aNSCs) derived from the subvent

37 SIGNIFICANCE STATEMENT: Adult neural stem cells (aNSCs) in the hippocampus self-

38 mC is elevated during the differentiation of adult neural stem cells (aNSCs), and Tet2 is primarily r

39 mbryonic origin and related heterogeneity of adult neural stem cells (aNSCs).

40 n epigenetically regulate specific miRNAs in adult neural stem cells (aNSCs).

41 ial focus is given on issues such as whether adult neural stem cells are activated after neurodegener

42 lished in Science suggests that in primates, adult neural stem cells are allocated during early corti

43 Adult neural stem cells are rare, and little is known ab

44 is issue of Neuron, Jackson et al. show that adult neural stem cells (B cells) express PDGF receptors

45 er present a testable unifying hypothesis of adult neural stem cell behavior in vivo to outline a com

46 indicate that, compared with GFAP expressing adult neural stem cells, CD133(+) ependymal cells repres

47 the platform to study the dynamics of single adult neural stem cell fate decisions in response to com

48 us-dependent learning and FMRP regulates the adult neural stem cell fate through the translational re

49 Adult neural stem cells give rise to neurons, oligodendr

50 Understanding the biology of adult neural stem cells has important implications for n

51 ed in embryonic hypothalamic progenitors and adult neural stem cells, have recently been observed to

52 contribution to remyelination of a subset of adult neural stem cells, identified by their expression

53 Here we show that TLX maintains adult neural stem cells in an undifferentiated, prolifer

54 ctivation and self-renewal mode of quiescent adult neural stem cells in response to neuronal activity

55 t the identity, organization and function of adult neural stem cells in the human SVZ are unknown.

56 tricular zone (SVZ) is a principal source of adult neural stem cells in the rodent brain, generating

57 ional deletion of Pten in a subpopulation of adult neural stem cells in the subependymal zone (SEZ) l

58 Here, we show that ablating Pten in adult neural stem cells in the subgranular zone of hippo

59 y and functionally restricted populations of adult neural stem cells in the subventricular zone.

60 Adult neural stem cells in the ventricular-subventricula

61 roliferation and neuronal differentiation of adult neural stem cells in vivo, which leads to impaired

62 ifferentiate stem cell populations including adult neural stem cells into neurons; however, the in vi

63 hat leads to integration of new neurons from adult neural stem cells into the existing circuitry.

64 The developmental origin of adult neural stem cells is not known.

65 he birth and integration of new neurons from adult neural stem cells, is a striking form of structura

66 generates functional neural cell types from adult neural stem cells, is dynamically regulated by bot

67 onounced evidence of ZIKV infection in these adult neural stem cells, leading to cell death and reduc

68 ese studies show that Prdm16 is required for adult neural stem cell maintenance and neurogenesis as w

69 nergic nigral afferents in the regulation of adult neural stem cell maintenance, identifying the firs

70 r results reveal a remarkable ability of the adult neural stem cell niche to retain proper function e

71 vasculature is an important component of the adult neural stem cell niche, but whether vascular cells

72 ila epithelium and retina, as well as in the adult neural stem cell niche.

73 cts as a mediator of quiescence in the V-SVZ adult neural stem cell niche.

74 nction within the subventricular zone of the adult neural stem cell niche.

75 t that REST/NRSF is required to maintain the adult neural stem cell (NSC) pool and orchestrate stage-

76 Adult neural stem cells (NSCs) are defined by their inhe

77 The mechanism by which adult neural stem cells (NSCs) are established during de

78 re found to be required for the formation of adult neural stem cells (NSCs) in the hippocampal dentat

79 Adult neural stem cells (NSCs) in the ventricular-subven

80 The quiescence of adult neural stem cells (NSCs) is regulated by local par

81 To explore this question, we cultured adult neural stem cells (NSCs) on variable stiffness ECM

82 oenvironment regulate the differentiation of adult neural stem cells (NSCs) toward the neuronal linea

83 Postnatal/adult neural stem cells (NSCs) within the rodent subvent

84 nt DNA damage responses between neonatal and adult neural stem cells (NSCs).

85 Inducible erk5 deletion in adult neural stem cells of transgenic mice inhibits neur

86 The adult neural stem cell pool is composed of orphan nuclea

87 he process of generating mature neurons from adult neural stem cells, proceeds concurrently with ongo

88 Adult neural stem cells/progenitor cells residing in the

89 trate that TLX (also called NR2E1) regulates adult neural stem cell proliferation in a cell-autonomou

90 provide useful experimental tools to advance adult neural stem cell research.

91 Adult neural stem cells reside in specialized niches tha

92 Adult neural stem cells reside in specialized niches.

93 godendrocyte progenitor cells and endogenous adult neural stem cells resident within the subventricul

94 Both embryonic and adult neural stem cells respond, allowing extensive prod

95 The mechanisms that control adult neural stem cell self-renewal are still largely un

96 ct also expressed in other regions harboring adult neural stem cells, suggesting that Sox9 represents

97 Ependyma have been proposed as adult neural stem cells that provide the majority of new

98 vironment controls the fate specification of adult neural stem cells, we discovered that adult astroc

99 molecular mechanisms by which REST regulates adult neural stem cells, we perform chromatin immunoprec