ライフサイエンスコーパス: advanced

1 Average date of kestrel nesting advanced 15 days in the past 24 years and was positively

2 Here, by using advanced 3D fabrication techniques we integrated a micro

3 NCODE) project, have been generated, we have advanced a newer more memory-efficient version of the al

4 Subsequently, ice advanced across and retreated from the Sabrina Coast con

5 e ORR or the OER; however, the origin of the advanced activity of oxygen electrocatalysts is still so

6 tive diagnosed at >/=60 years with CRC or an advanced adenoma can be offered average-risk screening o

7 tein combinations that differentiated CRC or advanced adenoma from control samples.

8 erformed hemoglobin in discriminating CRC or advanced adenoma from control samples.

9 with a family history of CRC or a documented advanced adenoma in a first-degree relative age <60 year

10 Large polyps, advanced neoplasia (advanced adenomas and cancer), and invasive cancer were

11 of cancer, including colorectal cancer (and advanced adenomas), endometrial cancers, and breast canc

12 intake and the prevalence of any adenomas or advanced adenomas.

13 nce, and rapid progression of some polyps to advanced adenomas.

14 In our cohort, advanced age (>67) was the strongest predictor of overal

15 as cholangiocarcinoma (n = 594); patients of advanced age at diagnosis had an increased incidence com

16 Among risk factors for CDI, the advanced age threshold was younger for Chinese patients

17 fusal in patients considered "too well" were advanced age, male sex, university hospital admission, c

18 of cholinergic hypofunction in patients with advanced Alzheimer's disease.

19 ALA intake was not associated with advanced AMD in either time period.

20 ion leads to a large increase in the risk of advanced AMD in some genotype subgroups.

21 Using advanced analytical and imaging techniques, such as vibr

22 Advanced analytical techniques currently used for charac

23 The observations of the additive effects of advanced and delayed precipitation peaks indicate semiar

24 During warmer spring and autumn, GSstart is advanced and GSend delayed, respectively.

25 ussion, with stronger consensus in high-risk/advanced and metastatic setting.

26 Advanced applications of polymeric self-assembled struct

27 metabolomics (SIRM) is an approach that uses advanced approaches of NMR and mass spectrometry to anal

28 201 patients (2011-2013) identified 68 with advanced ASS1-deficient malignant pleural mesothelioma.

29 thymus after dexamethasone treatment and in advanced atherosclerotic lesions in fat-fed Ldlr(-/-) mi

30 atherosclerotic plaques in humans as well as advanced atherosclerotic lesions in mice demonstrated ac

31 nhibitor, is approved for use in adults with advanced basal-cell carcinoma.

32 h as vismodegib, are effective therapies for advanced BCCs.

33 inuous, clinical-quality health monitors and advanced, bioelectronic therapeutics.

34 use gas emissions include their capture into advanced biofuels, such as butanol.

35 in wearable electronics systems, and toward advanced bionic skin applications.

36 al metastases, the leading cause of death in advanced breast cancer patients, depend on tumor cell in

37 ears) with centrally confirmed HER2-positive advanced breast cancer previously treated with both tras

38 t in patients with hormone receptor-positive advanced breast cancer who were not given dexamethasone

39 tients with previously treated HER2-positive advanced breast cancer, and validate HER2 as a therapeut

40 ated into major advances in the treatment of advanced breast cancer, with several targeted therapies

41 que cohort of more than 10,000 patients with advanced cancer and available pathological and clinical

42 mmonly in neoplasia but its contributions to advanced cancer have not been assessed directly.

43 These challenges demonstrate the need for advanced cancer imaging informatics tools that can help

44 This expression significantly increases at advanced cancer stages, providing an improved opportunit

45 tion training and coaching for patients with advanced cancer was effective in improving patient-cente

46 ear after diagnosis, 71% of individuals with advanced cancer were hospitalized, 16% had three or more

47 Since May 2015, 1040 of these patients with advanced cancer were referred by their oncologists for g

48 inal cohort study of 265 adult patients with advanced cancer who visited 38 oncologists within commun

49 tively characterized cohort of patients with advanced cancer, 642 of 1,168 (55%) with KRAS mutations

50 vailable treatment options for patients with advanced cancer.

51 he clinical benefit of ICIs in patients with advanced cancer.

52 y of life (QOL) and mood among patients with advanced cancer.

53 GFbeta appears to promote the progression of advanced cancers.

54 SILMs have been proposed for advanced carbon capture materials.

55 the results from the cohort of patients with advanced cervical cancer.

56 VIM sequence were performed on 30 women with advanced cervical cancers at three time points (within 2

57 re (CEC) initiative-to include patients with advanced chronic kidney disease and kidney transplant re

58 routine laboratory data was able to predict advanced chronic kidney disease following hospitalizatio

59 Advanced chronic kidney disease was defined by a sustain

60 ugh further validation in patients with more advanced cirrhosis and renal dysfunction is required.

61 intervention over provision of care only for advanced CKD is still evolving in many countries.

62 late 2016 and several other compounds are in advanced clinical trials.

63 Advanced colorectal cancer (CRC) remains a critical heal

64 with a new primary endpoint in patients with advanced colorectal cancer.

65 ) in information processing, for example, in advanced computational systems, smart actuators, and pro

66 Advanced congenic lines were developed to reduce the phy

67 velopment, and function of primary cilia has advanced considerably in recent years, revealing pathoge

68 ted signaling pathways that are important in advanced CRC.

69 In 1 patient with locally advanced cSCC who was treated with pembrolizumab, nearly

70 Patients and Methods Patients with locally advanced (cT3-4 or cN+) rectal cancer who were treated w

71 onists induce profound clinical responses in advanced cutaneous melanoma, but complete remissions are

72 Recent advanced developments in biosensing approaches for cance

73 mineralocorticoid receptor antagonists, and advanced device therapies.

74 or noncentral GA and at least 1 eye without advanced disease (n = 317).

75 ilable to relieve suffering in patients with advanced disease and at the end of life.

76 We show that Aurora A levels increase in advanced disease and AURKA is an AR-V target gene demons

77 eference values were poorer among those with advanced disease compared with patients with limited or

78 More advanced disease may require chemotherapy, radiotherapy,

79 om were followed up) were older and had more advanced disease than trial participants.

80 cular involvement is common, particularly in advanced disease, and that left-dominant forms occur.

81 In advanced disease, chemotherapy with anthracyclines and/o

82 with a diffuse pattern had more features of advanced disease, higher international staging system sc

83 y of patients with colon cancer will develop advanced disease, with the liver being the most common s

84 lone suggesting similar stromal signaling in advanced disease.

85 should detect early-stage cancer and prevent advanced disease.

86 d allowed good progression detection even in advanced disease.

87 ts is increasing beyond the scope of locally advanced disease.

88 ymphocytes early in disease and B cells with advanced disease.

89 ects of puerarin in an experimental model of advanced DN and provide a molecular mechanism by which p

90 Specific concerns raised by advanced donation include the management of uncertainty,

91 liposomal structures with high potential as advanced drug delivery vehicles, bioreactors and artific

92 re, we describe a total of 119 patients with advanced EGFR-TKI-naive NSCLC and 15 EGFR-TKI-resistant

93 Indeed, various advanced electrocatalysts have been designed for the ORR

94 or metastatic pancreatic adenocarcinoma and advanced epithelial ovarian cancer.

95 enia in the multimodal management of locally advanced esophageal cancer (LAEC), and to assess its ind

96 Consequently, advanced extraction techniques showed good lipid yields

97 ne level was the only factor associated with advanced fibrosis (adjusted OR, 1.044; P = 0.025).

98 We aimed to prospectively assess the risk of advanced fibrosis in first-degree relatives of probands

99 c scar in NASH is actively remodeled even in advanced fibrosis, a disease that is generally regarded

100 mice with ethanol-induced liver disease and advanced fibrosis, and controls, were given injections o

101 FLD-cirrhosis have a 12 times higher risk of advanced fibrosis.

102 reases in total follicles and percentages of advanced follicles.

103 ructure of these regeneration tracks has not advanced for decades and the structure of the cells that

104 in sediment porewater has been sufficiently advanced for organic compounds in the low- to midrange o

105 targeted drug delivery system, which can be advanced for the treatment of atherosclerosis and other

106 tailored sequences that are associated with advanced functions.Nature can precisely control monomer

107 es, for the first time, the applicability of advanced FWI methods to three-dimensional seismic field

108 atients previously treated for HER2-positive advanced gastric cancer (unresectable, locally advanced,

109 Eligible patients had HER2-positive advanced gastric cancer and progressed during or after f

110 re for first-line treatment of HER2-positive advanced gastric cancer, there is no established therapy

111 rtion of patients responding to treatment in advanced gastric cancer.

112 ocal density approximation (LDA) to our most advanced general purpose meta-generalized gradient appro

113 rapid life cycle, small (440-Mb) genome, and advanced germplasm resources make birch an attractive mo

114 inib, in a large population of patients with advanced GIST.

115 op microcystoid macular changes increased at advanced glaucoma and epiretinal membrane stages.

116 ents and compared global change over time in advanced glaucoma eyes.

117 While the utility of NFL declines in advanced glaucoma, GCC remains a sensitive progression d

118 In advanced glaucoma, more GC-IPL tissue remains above the

119 tly discordant in eyes with thin corneas and advanced glaucoma.

120 lglyoxal (MG) is a predominant precursor for advanced glycation end products (AGEs) due to its protei

121 g the effects of consumption of diets low in advanced glycation end products (AGEs) on cardiometaboli

122 we investigated the role of the receptor for advanced glycation end products (RAGE) in neuroinflammat

123 The receptor for advanced glycation end products (RAGE) is highly express

124 9 (S100A8/A9) interact with the receptor for advanced glycation end products (RAGE) on hepatic Kupffe

125 einase cleavage product soluble receptor for advanced glycation end products were significantly atten

126 s receptors TLR4/MD-2 and RAGE (receptor for advanced glycation end products) are not involved.

127 n of the nuclear isoform of the Receptor for Advanced Glycation End-products (nRAGE) in DSB-repair.

128 nd effective strategy with which to engineer advanced graphene-based functional nanocomposites with r

129 nse to radiotherapy and cetuximab in locally advanced head and neck squamous cell carcinoma (HNSCC) a

130 Invasion is a hallmark of advanced head and neck squamous cell carcinoma (HNSCC).

131 We randomly assigned patients with advanced heart failure to receive either the new centrif

132 ssociated with recurrence and mortality were advanced heart failure, VT cycle length, and a left-side

133 obstructive hypertrophic cardiomyopathy and advanced heart failure.

134 the therapy of choice for all patients with advanced heart failure.

135 y chemotherapeutic approved for treatment of advanced hepatocellular carcinoma (HCC).

136 baseline quantities of TILs in patients with advanced HER2-positive breast cancer treated with either

137 y provide a blueprint for the development of advanced heterogeneous catalysts with similar degrees of

138 The authors randomized 150 patients with advanced HF between August 15, 2012, and June 25, 2015,

139 disciplinary palliative care intervention in advanced HF patients showed consistently greater benefit

140 IV prevalence, patients present to care with advanced HIV infection and with a low CD4 cell count or

141 wana, there is still a substantial burden of advanced HIV, with 2013-2014 incidence of CM comparable

142 With wide ART availability, the burden of advanced human immunodeficiency virus (HIV) and associat

143 e combined a nanoscale imaging approach with advanced image analysis to detect individual vesicle fus

144 p visits (every 6 months) in the multicenter Advanced Imaging for Glaucoma Study.

145 f Atrophy Meeting [CAM]) on conventional and advanced imaging modalities used to detect and quantify

146 Advanced imaging showed promise for evaluating RP progre

147 Recent studies utilizing advanced imaging technologies have helped clarify these

148 Among HIV-infected patients with advanced immunosuppression, enhanced antimicrobial proph

149 e highest degree of protection and should be advanced in clinical development.

150 We utilize some advanced in situ characterisation techniques including s

151 der oxygen at atmospheric pressure, by using advanced in situ electron microscopy.

152 Implementation of more advanced in situ measurement devices could be easily acc

153 tors against this complex have been recently advanced in the clinic and have shown significant activi

154 ecently, there have been increased calls for advanced in vitro multi-cellular models that provide rel

155 ss to wireless optofluidic neural probes for advanced in vivo pharmacology and optogenetics in freely

156 ustomized hardware, expensive apparatus, and advanced informatics or can only be used in single exper

157 to inefficient mixing, aggregation, and the advanced instrumentation required for effective actuatio

158 erally time consuming and require the use of advanced instrumentation.

159 uencing of resident CD45(-) joint cells from advanced interval-specific recombinant congenic lines id

160 pan-JAK inhibitor 2 (PF-06263276), which was advanced into clinical studies.

161 , along with the southern margin of the CIS, advanced into recently deglaciated regions during the Bo

162 Compound 3 is thus a promising advanced lead compound for the development of drugs for

163 for compact accelerator building blocks and advanced light sources.

164 with the biocatalytic properties of hSOX for advanced light-controlled bioelectronics.

165 g eribulin with dacarbazine in patients with advanced liposarcoma (LPS) or leiomyosarcoma showed a si

166 lerates tumour progression when activated in advanced lung adenocarcinomas.

167 studies focused exclusively on patients with advanced lung and thymic carcinoids.

168 We advanced LUR models for benzene, toluene, ethylbenzene,

169 anding brain network architecture, employing advanced magnetic resonance imaging methods that quantif

170 RTS,S is an advanced malaria vaccine candidate and confers significa

171 lume to value are discussed, from the use of advanced management strategies that improve workflow to

172 ality of life, and survival of patients with advanced mastocytosis are expected to improve in the com

173 tures have found interesting applications as advanced materials in biomedicine, tissue engineering, r

174 s, agrochemicals and biologically active and advanced materials.

175 ABSTRACT: Advanced maternal age (>/=35 years) is associated with i

176 Pregnancies in women of advanced maternal age (AMA) are susceptible to fetal gro

177 To test whether advanced maternal age at birth independently increases t

178 g trend to utilize nanoplasmonic sensors for advanced measurement capabilities, including positional

179 that alpha-synuclein is highly beneficial to advanced melanoma because it ensures that autophagy is m

180 Although the treatment landscape for advanced melanoma has changed since this study was initi

181 s MD Anderson Cancer Center of patients with advanced metaplastic TNBC.

182 n humans were investigated in a patient with advanced metastatic PCa via sequential planar whole-body

183 e efficacy of PD-1 blockade in patients with advanced mismatch repair-deficient cancers across 12 dif

184 otosynthesis in soybeans was tested using an advanced model of canopy photosynthesis.

185 y structures has been instrumental to enable advanced molecular understanding of their intriguing pro

186 rophyll a and chlorophyll b is necessary for advanced monitoring of plant growth.

187 predicted model, setting the stage for more advanced motors for functional dynamic systems.

188 here is great enthusiasm for clinical use of advanced MRI-guided radiotherapy systems.

189 apeutic applications, but the identification advanced much faster than our understanding of stem/prog

190 bly into genes and genomes has significantly advanced multiple scientific disciplines.

191 y of enasidenib in patients with mutant-IDH2 advanced myeloid malignancies.

192 oach forms a foundation for the formation of advanced nanocomposite membranes comprising diverse buil

193 Large polyps, advanced neoplasia (advanced adenomas and cancer), and i

194 trials to improve and guide therapeutics via advanced neurobiological understanding of each disorder.

195 tifying tumor-driving genes in patients with advanced non-small cell lung carcinoma (NSCLC), especial

196 (IMRT) is increasingly used to treat locally advanced non-small-cell lung cancer (NSCLC), IMRT and th

197 emotherapy with bevacizumab in patients with advanced nonsquamous NSCLC.

198 ompares 3D-CRT and IMRT outcomes for locally advanced NSCLC in a large prospective clinical trial.

199 cetuximab with chemotherapy in patients with advanced NSCLC who are EGFR FISH-positive.

200 Of the 119 patients with advanced NSCLC, 27.7% (33/119) were suitable for treatme

201 rognosis in chemotherapy-naive patients with advanced NSCLC, we recruited all those who underwent (18

202 -line standard of care for PD-L1-expressing, advanced NSCLC.

203 ocetaxel in previously treated patients with advanced NSCLC.

204 s that do not experience helium swelling for advanced nuclear reactor applications.

205 SiC is considered for applications in advanced nuclear systems, as well as for electronic or s

206 However, ClusPro also offers a number of advanced options to modify the search; these include the

207 ne-receptor-positive, HER2-negative, locally advanced or metastatic breast cancer, who had relapsed o

208 Among patients with KRAS wt untreated advanced or metastatic colorectal cancer, there was no s

209 (aged >/=18 years) with unresectable locally advanced or metastatic gastric or gastro-oesophageal jun

210 l clinical applications for the treatment of advanced or metastatic pancreatic adenocarcinoma and adv

211 It recruits men with high-risk, locally advanced or metastatic prostate cancer who were initiati

212 Purpose Systemic Therapy for Advanced or Metastatic Prostate Cancer: Evaluation of Dr

213 many years, first-line treatment for locally advanced or metastatic soft-tissue sarcoma has been doxo

214 n selecting first-line treatment for locally advanced or metastatic soft-tissue sarcoma.

215 vanced gastric cancer (unresectable, locally advanced, or metastatic gastric cancer, including adenoc

216 While many studies advanced our understanding of how microtubule-associated

217 tic resonance spectroscopy (NMR) has greatly advanced our understanding of the composition of organic

218 ome analysis on diseased tissues has greatly advanced our understanding of the regulatory networks th

219 Only 40% of patients with advanced ovarian cancer survive more than 5 years.

220 nogenic acridine products known to form when advanced oxidation methods are used in water treatment.

221 aviolet (UV) and free chlorine (UV-chlorine) advanced oxidation process that produces highly reactive

222 -C(254 nm) photolysis, and the corresponding advanced oxidation processes (AOPs) (i.e., O3/H2O2 and U

223 UV-based advanced oxidation processes (AOPs) effectively degrade

224 y of these probes for use in electrochemical advanced oxidation processes (EAOPs), due to the neglect

225 Plasma oxidative stress (advanced oxidative protein product) was higher in SAH ve

226 care chemotherapies in preclinical models of advanced pancreatic and ovarian cancer.

227 patients with histologically proved locally advanced pancreatic cancer 5 cm or smaller (13 women, 12

228 reversible electroporation (IRE) for locally advanced pancreatic cancer and (b) evaluate the quality

229 usual care in reducing distress in men with advanced PC.

230 abine has shown efficacy in the treatment of advanced PDAC and was considered to improve survival in

231 Further inquiry into why advanced perioperative care did not reduce cardiac compl

232 rate of NFL thinning slowed dramatically in advanced PG, but GCC thinning rate remained relatively s

233 s. 38.7%, P < .001), but not in moderate and advanced PG.

234 treatment-free phase, no progression toward advanced phase CML occurred, and all relapsing patients

235 having an 'older'-appearing brain relates to advanced physiological and cognitive ageing and the risk

236 hree hundred three nurses, intensivists, and advanced practice providers.

237 alutamide is widely used in the treatment of advanced prostate cancer (PCa) in many countries, but it

238 nregulation was consistently observed in the advanced prostate cancer in 18 available clinical data s

239 a candidate therapeutic target for treating advanced prostate cancer.

240 .8) closer to adult height and reported more advanced pubertal development (P < 0.04).

241 Further, meticulous surgical techniques and advanced radiation protocols must be applied.

242 In the PRT setting of locally advanced RC, SRCC patients had significantly worse progn

243 cs and texture analysis in the management of advanced RCC will also be discussed.

244 For the past decade, advanced renal cell carcinoma (RCC) has been at the fore

245 Liver transplant candidates with advanced renal dysfunction and HCC may be considered for

246 ter lens-sparing vitrectomy (LSV) surgery in advanced retinopathy of prematurity (ROP).

247 However, more advanced right-sided lesions were detected at follow-up

248 treated with both trastuzumab and lapatinib (advanced setting) and a taxane (any setting) and with pr

249 on two or more HER2-directed regimens in the advanced setting.

250 anib is US FDA approved for the treatment of advanced soft tissue sarcomas.

251 ed cell death receptor 1 [PD-1] antibody) in advanced solid tumours expressing programmed cell death

252 with cobalt-nitrogen sites, confirmed by the advanced spectroscopic characterization.

253 Here, we combine advanced spectroscopy and microscopy on model Pd/C sampl

254 25 Gy) for early stage (IA, IB, and IIA) and advanced stage (IIB-IV) with bulky disease.

255 lped to elucidate the general picture of the advanced stage of plant cell specialization and to revea

256 eral ocular involvement at presentation, and advanced stage were significantly correlated with shorte

257 ase progressing from the intermediate to the advanced stage.

258 , 31; 4-6 months, 31; and 7-9 months, 43) or advanced-stage disease (cases per 1000 8-30 days, 8; 2 m

259 the success of future targeted therapies in advanced-stage disease.

260 in a large national population of women with advanced-stage EOC.

261 firms the favorable outcome of patients with advanced-stage FL treated with immunochemotherapy.

262 might represent a new therapeutic option for advanced-stage follicular lymphoma.

263 when added to platinum-based chemotherapy in advanced-stage non-squamous NSCLC.

264 Patients with suspected advanced-stage ovarian cancer who qualified for PCS were

265 -617 radioligand therapy (RLT) is applied in advanced-stage prostate cancer.

266 or-initiating cells (TIC) is vital to combat advanced-stage recurrent cancers.

267 ve increased survival times of patients with advanced-stage tumors, such as melanoma or lung cancer.

268 This isoform is highly expressed in advanced stages of breast and cervical tumors.

269 At advanced stages of FSGS, fawn-hooded hypertensive rat ki

270 g on episodic memory and motor function with advanced stages of HIV infection suggests that these two

271 anhydroglucitol (1,5-AG) are associated with advanced stages of kidney disease independent of kidney

272 Advanced stages of liver cirrhosis lead to a dramaticall

273 sults show that the retinal transcriptome at advanced stages of RP is very similar to that of other r

274 n increase in proinflammatory MC function in advanced stages of the disease.

275 ogs, rcd1 and xlpra2, at clinically relevant advanced stages of the two diseases.

276 ; thus, novel approaches to the treatment of advanced stages of this non-Hodgkin lymphoma are clearly

277 sensitive progression detector from early to advanced stages.

278 hin fully MH Ericaceae plastomes suggests an advanced state of degradation.

279 nts and neurological outcomes reporting have advanced substantially.

280 ia reaction then enabled the synthesis of an advanced synthetic intermediate containing the EF and G

281 For patients with locally advanced (T3, T4) disease, organ-preservation surgery, c

282 The advanced techniques of Deep Learning can be used to iden

283 opportunities for applications that require advanced temperature and heat regulations.

284 crystallization particles have significantly advanced the area of polymer assembly.

285 The GRN approach has advanced the fields of genomics and development, and we

286 l, we show that Californian bird communities advanced their breeding phenology by 5-12 d over the las

287 absorption spectroscopy (XAS)) coupled with advanced theoretical calculations has been applied for t

288 nctioning neural elements is a major goal of advanced therapeutic systems for brain cancer.

289 Compound 25 was advanced to first-in-man trials for the treatment of psy

290 how that the West Antarctic Ice Sheet (WAIS) advanced to the eastern Ross Sea shelf edge during the L

291 mechanisms, multiple vaccine strategies have advanced to the stage of clinical evaluation with unprec

292 Here advanced tractography was combined with quantitative ind

293 n the four-channel case is expected to yield advanced transmission and absorption regimes.

294 ng through reverse osmosis (RO) units within advanced treatment trains for the potable reuse of munic

295 ir elevated expression is associated with an advanced tumor state and a poor prognosis.

296 mpact of neoadjuvant pretreatment in locally advanced tumors should be considered with caution in ter

297 ged 15 years or older with a diagnosis of an advanced unresectable or metastatic soft-tissue sarcoma,

298 study if they had pathologically confirmed, advanced (unresectable or metastatic), non-functional, w

299 Three patients with advanced VHL-related juxtapapillary RCH treated with sys

300 Many explanations for TLD have been advanced, with recent efforts focused on recombination p