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1 e were 218 patients in the protocol (98 with advanced stage).
2 in asymptomatic until the disease reaches an advanced stage.
3 ith increased resection correlated with more advanced stage.
4 prognosis, particularly when diagnosed at an advanced stage.
5 omas characterized by only poor prognosis in advanced stage.
6 ase progressing from the intermediate to the advanced stage.
7 pharyngeal cancers are often diagnosed at an advanced stage.
8 est survival when treatment was initiated at advanced stage.
9 sensitive progression detector from early to advanced stages.
10 crospore formation but had no effect on more advanced stages.
11 rcinoma (HCC), which is usually diagnosed at advanced stages.
12 early stages from the referable intermediate/advanced stages.
14 mor diameter, para-aortic nodal involvement, advanced stage, ADC90 and ADC95, nADC75, nADC90, and nAD
15 lable for up to 11,239 cases (including 1654 advanced stage and 1741 aggressive) and 18,541 controls
16 hat the MnSOD/AMPK pathway is most active in advanced stage and aggressive breast cancer subtypes.
18 re its appearance in older male individuals, advanced stage and bilateral manifestation at the time o
19 ocarcinoma (CC) is typically diagnosed at an advanced stage and is refractory to surgical interventio
22 cinoma (CCRCC) is an incurable malignancy in advanced stages and needs newer therapeutic targets.
24 indicate that LGR5 expression was reduced in advanced stages and positively correlated with markers o
25 he elevated TIP-1 levels are associated with advanced staging and poor prognosis in glioma patients.
26 phorus was associated with increased risk of advanced-stage and high-grade disease 0-8 y after exposu
27 ake was associated with an increased risk of advanced-stage and high-grade disease 12-16 y after expo
30 xpress high levels of HSP70, particularly at advanced stages, and that phospho-FAK (PTK2) and BRAF ar
31 8 years or older) with previously untreated, advanced stage (Ann Arbor stage III or IV) follicular ly
33 avorable risk, early stage unfavorable risk, advanced stage [AS] III/IV) and progression-free surviva
37 th early-stage favorable than unfavorable or advanced stage at first diagnosis (15-year cumulative in
41 is, and therapeutic monitoring from early to advanced stage cancer patients and to examine underlying
42 r extrahepatic cancer are considered to have advanced-stage cancer and could benefit from treatment w
44 opulation of immature myeloid cells found in advanced-stage cancer patients and mouse tumor models.
45 sion of CD38(+) MDSCs in peripheral blood of advanced-stage cancer patients and validated targeting C
48 (14.6% vs 0% [GOG trials were restricted to advanced-stage cancer]); and nonserous carcinomas (29.9%
49 wever, most previous studies have focused on advanced stage cancers, and few have evaluated ctDNA det
50 al colorectal adenocarcinomas, including 255 advanced-stage cancers, and 147 deaths from interval col
60 , 31; 4-6 months, 31; and 7-9 months, 43) or advanced-stage disease (cases per 1000 8-30 days, 8; 2 m
62 ches are used for refractory early-stage and advanced-stage disease (IIB-IV) and include bexarotene,
63 1.05-2.08]; 49 cases per 1000 patients) and advanced-stage disease (OR, 1.97 [95% CI, 1.14-3.42]; 19
64 1.89-2.68]; 76 cases per 1000 patients) and advanced-stage disease (OR, 3.22 [95% CI, 2.44-4.25]; 31
65 her likelihood of solid subtype ( P < .001), advanced-stage disease at diagnosis ( P = .02), higher r
69 9; and the HD15 trial enrolled patients with advanced-stage disease from Jan 28, 2003, to April 18, 2
73 biologic agents available, the treatment of advanced-stage disease still represents an unmet medical
75 orld Health Organization classification with advanced-stage disease were identified and paired 1:2 wi
77 re deprived area, nonwhite ethnicity, having advanced-stage disease, having undergone radiotherapy, a
85 association was strongest for patients with advanced-stage EAC: in a stratified analysis, comparison
89 y downregulated in poorly differentiated and advanced-stage endometrial carcinoma compared with level
90 and chemotherapy that induces regression of advanced stage EOC and significantly improves survival.-
96 ed with NACT in otherwise healthy women with advanced-stage epithelial ovarian cancer aged 70 years o
98 0)Y-IT is an effective initial treatment for advanced-stage FL in patients with higher tumor burden r
105 18)F-FDG avidity in the index malignancy, an advanced stage for that malignancy, and a clinician deci
109 d effectiveness of therapy for patients with advanced stage head and neck squamous cell carcinoma (HN
110 e report survival outcomes for patients with advanced-stage hepatocellular carcinoma (HCC) with porta
111 his difference was largely explained by more advanced stage, higher grade tumors, and a greater propo
112 eighty newly diagnosed early unfavorable and advanced-stage HL patients, all scanned at baseline and
116 anuary 2001 and December 2009, patients with advanced-stage Hodgkin lymphoma who had responded comple
117 y during first-line therapy in patients with advanced-stage Hodgkin lymphoma, in terms of providing a
119 ge favourable, early-stage unfavourable, and advanced-stage Hodgkin's lymphoma from the HD13, HD14, a
121 N proto-oncogene is amplified in a number of advanced-stage human tumors, such as neuroblastomas.
123 ed on limited (stages I and II, nonbulky) or advanced (stage III or IV) disease, with stage II bulky
124 ized as localized (stages I and II), locally advanced (stages III and IVB), or metastatic (stage IVC)
125 r-naive patients with EGFR mutation-positive advanced (stage IIIb-IV) lung adenocarcinomas who were g
126 enus Thermus is more abundant in tissue from advanced stage (IIIB, IV) patients, while Legionella is
130 f TF has in clinical studies correlated with advanced stage, increased microvessel density, metastasi
132 confidence interval [CI], 0.39 to 0.69), for advanced-stage interval cancer, 0.43 (95% CI, 0.29 to 0.
134 skin cancer; its prognosis, particularly in advanced stages, is disappointing largely due to the res
137 e good diagnostic and prognostic utility for advanced stage liver disease, and have been adapted into
140 tment option for patients with asymptomatic, advanced-stage, low-tumour-burden follicular lymphoma.
141 I2 gene) and SOX9, which are associated with advanced stage lung cancers and are implicated in the re
143 146 family members of Medicare patients with advanced-stage lung or colorectal cancer in the Cancer C
144 ents and Methods We treated 22 patients with advanced-stage lymphoma in a clinical trial of CAR-19 T
145 y low-dose chemotherapy induced remission of advanced-stage lymphoma, and high serum IL-15 levels wer
146 early stages and gAD supplementation during advanced stages may potentially reduce the cerebral isch
149 shown therapeutic benefit, in both early and advanced stage metastatic disease, especially when used
150 (225)Ac-PSMA-617 alpha-radiation therapy in advanced-stage, metastatic castration-resistant prostate
151 includes the largest cohort of patients with advanced-stage MF/SS and identifies markers with indepen
154 CAI2 expression was significantly higher in advanced-stage neuroblastoma, independently of MYCN ampl
155 ptimal therapy and outcome for patients with advanced-stage nodular lymphocyte-predominant Hodgkin ly
156 we analyzed longitudinal blood samples from advanced stage non-small cell lung cancer (NSCLC) patien
157 -3'-(18)F-fluorothymidine ((18)F-FLT) PET in advanced-stage non-small cell lung carcinoma (NSCLC) pat
159 for elderly patients with a new diagnosis of advanced-stage NSCLC and were treated with antineoplasti
160 sion Considerable shifts in the treatment of advanced-stage NSCLC occurred along with modest gains in
163 c function, without structural injury, to an advanced stage of biventricular dysfunction (H), differe
164 factor at all disease stages, including the advanced stage of castrate-resistant prostate cancer (CR
166 Gastric cancer is usually diagnosed in an advanced stage of disease and treatment options are spar
167 d with pancreatic cancer clearly reflect the advanced stage of disease at diagnosis for most patients
168 cer; delays in diagnosis that result in more advanced stage of disease at presentation; inadequate re
169 of moderate to severe cataracts (P < .0001), advanced stage of glaucoma (P < .0001), and a diagnosis
173 lped to elucidate the general picture of the advanced stage of plant cell specialization and to revea
174 those that hold promise or are already at an advanced stage of testing (OsPSTOL1, AVP1, PHO1 and OsPH
175 f incurable disease status, knowledge of the advanced stage of the disease, and expectation to live m
177 ad centrifugally to tonsils and spleen at an advanced stage of the incubation period, thus explaining
178 nic drugs, but geographic atrophy (GA) is an advanced stage of the more prevalent "dry" form of AMD f
179 taben SUVRs appears to be negligible even in advanced stages of AD with a higher cerebellar Abeta loa
180 ls of complement, only uEVs of patients with advanced stages of ADPKD had increased levels of villin-
181 exaenoic acid (DHA) and the intermediate and advanced stages of age-related macular degeneration (AMD
182 ium of human eyes, particularly in eyes with advanced stages of age-related macular degeneration.
183 ith early (n = 9), intermediate (n = 5), and advanced stages of AMD (geographic atrophy, n = 5; neova
184 While reactive microgliosis is a hallmark of advanced stages of amyotrophic lateral sclerosis (ALS),
185 therefore seems to be a common event in the advanced stages of apoptosis, when caspase-3 is active.
189 el of GIT1 was significantly associated with advanced stages of breast cancer, as well as with lymph
191 cluding diabetes mellitus, hypertension, and advanced stages of chronic kidney disease at baseline.
192 endent prognostic indicator in patients with advanced stages of chronic lymphocytic leukaemia (CLL).
195 s, TGF-beta1 and IL-10, is a hallmark of the advanced stages of cutaneous T cell lymphoma (CTCL), whe
196 tripeptide-based HCV protease inhibitors in advanced stages of development for which cross-resistanc
197 e microscopes, (ii) scalability by analyzing advanced stages of development with up to 20,000 cells p
199 the SOCS1 peptidomimetic at either early or advanced stages of diabetes ameliorated STAT activity an
201 ven percent of eyes in decade 1 demonstrated advanced stages of disease (stage 3B or worse) compared
202 have been documented in patients treated at advanced stages of disease, including improvement in liv
203 lgus macaques when treatment is initiated at advanced stages of disease, including up to 8 d after ch
205 nd factor, in human and rat liver tissue, at advanced stages of fibrosis caused by either biliary or
208 mineralocorticoid receptor blockers in less advanced stages of heart, renal, and vascular disease.
209 g on episodic memory and motor function with advanced stages of HIV infection suggests that these two
211 anhydroglucitol (1,5-AG) are associated with advanced stages of kidney disease independent of kidney
214 8 patients with persistent HCV infection and advanced stages of liver fibrosis or cirrhosis and 20 co
216 (NP-targeting) siRNA in nonhuman primates at advanced stages of MARV or RAVV disease to mimic cases i
217 w being used more commonly for patients with advanced stages of melanoma, can exacerbate autoimmune d
220 ges (with a high peroxide value) and oils in advanced stages of oxidation, with secondary oxidation c
221 ocyte levels were significantly increased in advanced stages of PAOD, while classical and non-classic
223 patients in 3 groups of mild, moderate, and advanced stages of PD were recruited for 18F-DTBZ PET sc
224 ere seen in poorly differentiated and highly advanced stages of prostate cancer and correlated with p
227 sults show that the retinal transcriptome at advanced stages of RP is very similar to that of other r
229 as to determine the association between more advanced stages of temporomandibular joint (TMJ) intra-a
231 the shift from a Th1 to a Th17 imbalance at advanced stages of the disease suggests the necessity to
232 ) is important for progression to the deadly advanced stages of the disease, it is poorly understood
242 ate well with reactive lysine content if the advanced stages of the reaction had not been reached.
244 a acts as a tumor suppressor, whereas in the advanced stages of these cancers, increased TGF-beta exp
246 ; thus, novel approaches to the treatment of advanced stages of this non-Hodgkin lymphoma are clearly
247 ized-system raises a promising treatment for advanced stages of this rare amyloidotic disease, and al
249 alformations of myelin ultrastructure in the advanced stages of Wallerian degradation is known, its s
250 e some form of palliation because of locally advanced stage or distant metastasis, where it cannot be
254 e surgery (PCS) by identifying patients with advanced-stage ovarian cancer in whom > 1 cm of residual
258 P = .01; HR, 6.75; 95% CI: 1.44, 120.5), and advanced stage (P = .03; HR, 3.16; 95% CI: 1.94, 4.56) w
263 diagnosis (and were otherwise untreated) to advanced stage patients with HCC who received no therapy
264 ssociated with melanoma-specific survival in advanced-stage patients (rs10515789, multivariate P=0.02
265 ancer drug therapies almost always occurs in advanced-stage patients even following a significant res
266 identified subsets of BCLC intermediate- and advanced-stage patients for more aggressive treatments t
267 nitial therapeutic response, the majority of advanced-stage patients relapse and succumb to chemoresi
273 no elevated risk for overall, high-grade or advanced-stage prostate cancer, or death due to prostate
275 -year cumulative risk of cancer after LT for advanced-stage PSC was 18.7%, with posttransplant lympho
283 ings of ADC value of early (stage I, II) and advanced stages (stage III, IV) of thymic epithelial tum
284 of the spindle-like tumours with metastasis, advanced stage, suboptimal debulking and poor prognosis.
285 = 15) and inactive older men and women with advanced-stage, symptomatic knee osteoarthritis (OA) (n
286 S are treated with cART alone; patients with advanced-stage (T1) KS receive cART plus liposomal anthr
287 al cancer (EC) are generally diagnosed at an advanced stage, translating into a poor survival rate.
288 multi-center integrated genomic analysis of advanced stage tumors with and without STIC lesions and
289 opean cohort, with a focus on high-grade and advanced-stage tumors, and death due to prostate cancer.
290 5OHD concentrations were lower in women with advanced-stage tumors, and the lowest in premenopausal w
291 ve increased survival times of patients with advanced-stage tumors, such as melanoma or lung cancer.
292 od tumors and their propensity to present at advanced stages, updated long-term data are needed.
293 eral ocular involvement at presentation, and advanced stage were significantly correlated with shorte
295 ith the majority of patients diagnosed at an advanced stage where curative therapeutic options are la
296 osed with epithelial ovarian cancer (EOC) at advanced stage, where therapies have limited effectivene
297 cell response was observed in patients at an advanced stage, whereas the coexpression of markers that
298 y and mortality owing to diagnosis at a more advanced stage, which suggests that nonwhite organ trans
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