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1  life history has greatly benefited from the advent and development of molecular epidemiology.
2                                          The advent and growth of synthetic biology has demonstrated
3                                          The advent and proliferation of mass drug administration (MD
4 ereal grains, a fundamental component of the advent and spread of farming.
5            It highlights current progresses, advents, and pitfalls within the field and discusses fut
6                                    Since its advent, iPSC technology has expanded with 3 major applic
7                                     With the advent of 16s rRNA sequencing replacing traditional cult
8                            Nevertheless, the advent of 2-sample approaches (in which exposure and out
9                                     With the advent of 3D printing, we predict that single-step fabri
10                                     With the advent of 7 T fMRI, it is increasingly feasible to map s
11  as a material and an energy source, and the advent of a lignocellulosic fuel industry will elevate i
12                        We are witnessing the advent of a new era of robots - drones - that can autono
13 y (EM) is experiencing a revolution with the advent of a new generation of Direct Electron Detectors,
14                                          The advent of a new generation of electron microscopes and d
15 tunability of MOFs, these results herald the advent of a new generation of supercapacitors whose acti
16                                          The advent of a viable vaccine and its deployment, coupled w
17                                          The advent of ablative fractional photothermolysis within th
18                       Observations: With the advent of advanced molecular diagnostic methods, a new p
19                                 However, the advent of advanced molecular tools and the rise of synth
20 istence lifestyle that was common before the advent of agriculture (see Supplemental Experimental Pro
21  has been a struggle for humankind since the advent of agriculture.
22                                          The advent of and recent advances in mouse genomics, epigeno
23                                          The advent of anti-vascular endothelial growth factor treatm
24                                          The advent of antibody-drug conjugates as pharmaceuticals ha
25 ritional homeostasis, as demonstrated by the advent of antidiabetes therapies that alter gastrointest
26  had a refined ecology shortly following the advent of ants.
27                                          The advent of aqueous symmetric sodium-ion battery with high
28                                          The advent of array-based genome-wide DNA methylation method
29                               Today with the advent of automated algorithms, vibrational microspectro
30                                          The advent of autonomous self-propulsion has instigated rese
31                                          The advent of bacterial artificial chromosome technologies h
32 ts with cancer is increasing, reflecting the advent of better and more efficient therapies.
33  innovations in drug discovery including the advent of biologic therapeutic agents, has propelled Ras
34                                     With the advent of biosimilars to the U.S. market, it is importan
35 d a great deal of current attention with the advent of C-H functionalization reactions.
36                                     With the advent of camera-based imaging FCS, which measures the d
37                                          The advent of cancer immunotherapy has generated renewed hop
38 The 3-month survival rate improved after the advent of cART (38% vs 69%), with no difference between
39                                          The advent of cell reprogramming and induced pluripotent ste
40 eady state during growth was critical to the advent of cellular life.
41 lized olefins, from the first reports to the advent of chiral Crabtree-like catalysts.
42 ctionalized substrates, respectively, to the advent of chiral phosphoramidite ligands.
43                                   Before the advent of combination antiretroviral therapy (cART), rou
44                                          The advent of combined modalities such as PET/CT and PET/MR
45                                     With the advent of combined PET/MR imaging scanners, we are enter
46                                   The recent advent of commercial microwave source in the terahertz r
47                                          The advent of complex multicellularity (CM) was a pivotal ev
48                    Here, we propose that the advent of controlled fire use in early humans created th
49                                          The advent of controlled/living radical polymerisation (CLRP
50 een a topic of debate and revision since the advent of corrole chemistry.
51                                          The advent of counterfactual-based mediation analysis has tr
52                                     With the advent of covalent organic frameworks (COFs), the chemis
53                                          The advent of cross-linking immunoprecipitation coupled with
54         However, over the last 10 years, the advent of deep sequencing and other powerful technologie
55 Language (SBML) format, has evolved with the advent of different modeling formalisms in systems biolo
56                                          The advent of diffusion-weighted magnetic resonance imaging
57                                          The advent of Dirac materials has made it possible to realiz
58                          However, the recent advent of direct electron detectors has greatly improved
59                                          The advent of dissolution Dynamic Nuclear Polarization (dDNP
60                                          The advent of DNA footprinting with DNase I more than 35 yea
61 m millions of lives every year, but with the advent of drug resistance, therapeutic options to treat
62  though it was dramatically reduced with the advent of drug-eluting stents.
63                                     With the advent of drug-resistant bacteria, it is necessary to un
64                                    Until the advent of effective antivirals or monoclonal antibodies,
65 the past five decades, most notably with the advent of effective conjugate vaccines since the 1990s.
66                                     With the advent of effective modern chemotherapeutic and biologic
67                                          The advent of efficient approaches to the genetic modificati
68                                     With the advent of efficient in vitro selection technologies, the
69 olevel in the mid-twentieth century with the advent of electron microscopy.
70                                          The advent of Electronic Medical Records (EMR) with large el
71 tection system has been accelerated with the advent of emerging miniaturization techniques, advanced
72 atients and at least partly explained by the advent of endocrine therapy that is less effective in Af
73                                Yet, with the advent of endovascular thrombectomy and the ability to i
74                                          The advent of engineered DNA methyltransferases (MTases) to
75                                     With the advent of enhanced neuroimaging and functional neurosurg
76 ly events in primordial chemistry before the advent of enzymes.
77                            We infer that the advent of eusociality led automatically and unavoidably
78 be incompatible with life; however, with the advent of ex-utero intrapartum procedure, a few cases of
79                            However, with the advent of exome sequencing, humans with mutations in gen
80                                          The advent of facile genome engineering using the bacterial
81 extent of environmental influence before the advent of farming.
82                                          The advent of fluorescent proteins (FPs) for genetic labelin
83                   This was attributed to the advent of fully active and better-tolerated antiretrovir
84 blems were anticipated to be solved with the advent of fully biodegradable devices.
85                                          The advent of functional genomics has enabled the genome-wid
86 nced rapidly during the past decade with the advent of genome-wide association studies (GWAS).
87                                          The advent of genomic-, transcriptomic- and proteomic-based
88                                     With the advent of genomics technologies and genetic tools, impor
89                                          The advent of genotyping arrays enabled large-scale genome-w
90                                          The advent of Google Street View, which provides publicly av
91                                          The advent of graphene and related 2D materials has recently
92                                          The advent of hard x-ray free electron lasers (XFELs) capabl
93                                          The advent of hard x-ray free-electron lasers (XFELs) has op
94                         In recent years, the advent of high performance computing has facilitated org
95                                     With the advent of high throughput combination screening there is
96                                          The advent of high throughput data has led to a massive incr
97                                          The advent of high throughput RNA-seq at the single-cell lev
98                                     With the advent of high-definition SD-OCT imaging, we are now abl
99                                          The advent of high-intensity lasers enables us to recreate a
100                                          The advent of high-intensity, broadly tunable quantum cascad
101                                          The advent of high-resolution mass spectrometers provides a
102                                          The advent of high-speed time-lapse microscopy and its use i
103 sed 9-fold since 1995, partly reflecting the advent of high-throughput and virtual screens against mo
104                                          The advent of high-throughput DNA methylation profiling tech
105                                          The advent of high-throughput next generation sequencing tec
106        These genomic studies, as well as the advent of high-throughput sequencing and genome engineer
107                                          The advent of high-throughput sequencing has led to a tremen
108                                     With the advent of high-throughput sequencing of RNA (RNA-Seq), t
109                                          The advent of high-throughput sequencing technologies has br
110                                          The advent of high-throughput sequencing technology has resu
111                                   The recent advent of high-throughput sequencing-based structure pro
112                                          The advent of high-throughput techniques including sequencin
113                                     With the advent of high-throughput technologies making large-scal
114                                     With the advent of high-throughput, next-generation sequencing (N
115                                          The advent of high-throughput/high-content single cell techn
116                         Importance: With the advent of highly effective antiretroviral therapy and im
117                                     With the advent of highly efficient antiviral therapies for hepat
118 tina evolved in jawless vertebrates with the advent of highly photosensitive rod-like photoreceptors.
119 adays the major application of the WGSR, the advent of homogeneous catalysis in the 1970s marked the
120                                          The advent of hybrid cameras that combine MRI with either SP
121 modest response rates and duration until the advent of ibrutinib.
122 show that the timing of exposure matches the advent of ice-free conditions, strongly suggesting that
123 ug delivery is critical to develop given the advent of immunotherapy and the availability of novel bi
124                              With the recent advent of in vivo Tau-PET tracers it is now possible to
125                                   The recent advent of in-depth immune phenotyping projects in large-
126                                          The advent of induced pluripotent stem cells means that it m
127                                     With the advent of innovative technologies, new threats are conti
128                                          The advent of integrated PET/MR scanners allows us to exploi
129                           ABSTARCT: With the advent of intelligent manufacturing, phase measuring def
130 nd spread of injecting drug use, such as the advent of intravenous medical therapies and devices, and
131                                          The advent of large genome sequencing consortia, such as the
132                                     With the advent of large genotyping studies involving hundreds of
133                                     With the advent of large scale biological data collection for var
134                                          The advent of large-scale population recordings affords the
135                                          The advent of large-scale sequencing projects, such as the P
136                              In light of the advent of larger MSI data sets based on either an increa
137                          However, before the advent of life, it is generally assumed that chemical re
138                                          The advent of light-sheet microscopy now allows users to ove
139 elds and sampling algorithms, as well as the advent of low-cost parallel computing.
140           In this Review we describe how the advent of machines is impacting on organic synthesis pro
141                                     With the advent of magnetic resonance imaging (MRI), in-vivo anal
142                                          The advent of magnetic resonance imaging, which safely allow
143                                          The advent of mass cytometry enables simultaneous assessment
144                                          The advent of mass cytometry has led to an unprecedented inc
145 h techniques have been revolutionized by the advent of mass spectrometers with detectors that afford
146 field of genomics has grown rapidly with the advent of massively parallel sequencing technologies, al
147                                     With the advent of massively parallel sequencing, considerable wo
148                                          The advent of matrix-assisted laser desorption ionization-ti
149                                     With the advent of MDCT and MRI, accurate preoperative diagnosis
150                                    Since the advent of mechanically interlocked molecules (MIMs), man
151       The ubiquity of DNA sequencing and the advent of medical imaging, electronic health records, an
152                                     With the advent of metabolic engineering tools, the successful re
153                                Now, with the advent of metamaterials and their two-dimensional counte
154                                          The advent of microarrays, next-generation sequencing, prote
155             A new approach brought on by the advent of microsecond dwell times in single particle ICP
156                                          The advent of mobile DNA sequencers has made it possible to
157 hese multicellular organisms demonstrate the advent of mobility, heterotrophy by multicellular animal
158 ith the increasing average donor age and the advent of Model for End-stage Liver Diseases (MELD) scor
159 ith the increasing average donor age and the advent of Model for End-stage Liver Diseases (MELD) scor
160                                     With the advent of modern adjuvant chemotherapy strategies, posto
161                                          The advent of modern C-H functionalization chemistries has e
162 metabolism was largely ignored following the advent of modern molecular biology.
163 sociated with arthritis, at least before the advent of modern rheumatologic medications.
164                       Corresponding with the advent of modern surgical repairs, reproductive fitness
165                                          The advent of modern tools in neuroscience has allowed furth
166 metal pollution has been a problem since the advent of modern transportation, which despite efforts t
167 replication, the discovery of oncogenes, the advent of molecular cloning, the search for human cancer
168                                          The advent of molecular genetics has in the past several yea
169 al of vector monitoring has grown due to the advent of molecular methods capable of increasing the se
170                                          The advent of molecular technologies provides an opportunity
171 xperienced a brief fall from grace, with the advent of molecular tools, planarians, such as Schmidtea
172                                   Before the advent of monoclonal antibody (mAb) therapy, infection o
173                                 Although the advent of monoclonal antibody therapy has had a positive
174                             Given the recent advent of mononuclear single-molecule magnets (SMMs), a
175  of significant concern, especially with the advent of more disease-modifying treatments in MS that a
176 f computational chemistry increases, and the advent of more powerful computers decreases the amount o
177                                     With the advent of more sensitive and specific diagnostic tests,
178 nsideration the explosion of "big data," the advent of more sophisticated data collection and analyti
179                                          The advent of MR microscopy (MRM) enables imaging biological
180 ss than 20% improved to 65% to 70% after the advent of multiagent chemotherapy regimens.
181                                   The recent advent of multiparametric approaches for myocardial defo
182                                          The advent of mycobacterial genetics, sophisticated immunolo
183                                          The advent of myelin was instrumental in advancing the nervo
184                                 However, the advent of nanoscale and nanogap electrode geometries tha
185                                     With the advent of nanostructures and new interface materials, th
186                                          The advent of new dedicated solid-state cameras has opened n
187                                          The advent of new genomic technologies has resulted in the p
188 mic changes over the past 2 decades with the advent of new identification methods with higher discrim
189                                     With the advent of new initiatives to develop chemically defined
190                       Only recently with the advent of new technology and creation of highly speciali
191                                Moreover, the advent of new therapies may allow not only the preventio
192 more prevalent in modern society despite the advent of new treatments, representing a major global he
193                                     With the advent of new-generation whole-genome sequencing, many c
194                                     With the advent of newer and emerging forms of targeted biologic
195                                     With the advent of next generation high-throughput DNA sequencing
196                                     With the advent of Next Generation Sequencing the identification
197                                          The advent of next-generation DNA sequencing platforms has r
198  classes has been greatly facilitated by the advent of next-generation RNA sequencing which, by readi
199                                          The advent of next-generation sequencing (NGS) has created u
200                                          The advent of next-generation sequencing (NGS) in 2010 has t
201 tly, and slow to yield new insights, but the advent of next-generation sequencing (NGS) technologies
202 s in diagnostic technology, particularly the advent of next-generation sequencing (NGS).
203                                          The advent of next-generation sequencing has brought about a
204                                   The recent advent of next-generation sequencing has prompted mappin
205               In the past 5 yr, however, the advent of next-generation sequencing has radically chang
206                                     With the advent of next-generation sequencing technologies and th
207                                          The advent of next-generation sequencing technologies enable
208                                          The advent of next-generation sequencing technologies has ma
209                                          The advent of next-generation sequencing technologies will a
210                                     With the advent of next-generation sequencing technologies, the h
211                                          The advent of next-generation sequencing technology has grea
212                                     With the advent of Next-Generation Sequencing, automatic training
213                                          The advent of nonsurgical mechanical interventions for aorti
214                                     With the advent of novel chemotherapeutics and targeted molecular
215 hanged dramatically in recent years with the advent of novel tools for targeting genetically distinct
216                                     With the advent of novel treatment strategies to help widen the t
217 lyzed for RM system components, and with the advent of PacBio sequencing, the recognition sequences o
218 clic nucleotide field that culminated in the advent of PDE5 inhibitors that treat erectile dysfunctio
219 ins are purported serial homologues, and the advent of pelvic fins has been hypothesized to have resu
220 th the emergence of novel treatments and the advent of personalised medicine, and improved HRQOL tool
221                                          The advent of phototransformable fluorescent proteins has le
222                                 However, the advent of platform technologies offers vaccine manufactu
223                                     With the advent of portable touchscreen devices, this association
224 ith any major biological crises nor with the advent of potential competitors.
225 n the era of precision medicine and with the advent of powerful imaging and proteomics technologies,
226                                          The advent of powerful perturbation tools, such as optogenet
227 for studying cortical function, owing to the advent of powerful tools that can record and manipulate
228                                     With the advent of preliminary trial data, it can be reasonably a
229          In 1929, only three years after the advent of quantum mechanics, von Neumann and Wigner show
230                                    Given the advent of quantum technologies, a design for a quantum m
231 ave long fascinated humankind, and since the advent of radar entomology much has been revealed about
232                                          The advent of recombinant DNA technology allowed the express
233                                          The advent of renewable energy conversion systems exacerbate
234 e studied for disease associations since the advent of research molecular amplification assays.
235                                     With the advent of reversible covalent chemistry the study of the
236                                     With the advent of S63845, the targeting of BCL-2, BCL-XL, and MC
237 s field has been dramatically changed by the advent of safe and effective direct-acting antiviral the
238 e locations of the grounding line before the advent of satellite monitoring in the 1990s are poorly d
239                                    After the advent of screening mammography, the proportion of detec
240 ed per 100,000 women in the period after the advent of screening than in the period before screening)
241 rk in other clinical settings.IMPORTANCE The advent of sensitive sequencing platforms has led to an i
242                                     With the advent of sentinel lymph node biopsy, surgical methods f
243                                Even with the advent of sequence-specific nucleases, which stimulate h
244                               Meanwhile, the advent of several high-throughput sequencing techniques
245                                          The advent of sexual reproduction and the evolution of a ded
246                                     With the advent of single-cell sequencing, genomes of uncultivate
247                             Accordingly, the advent of single-cell technologies will be crucial in en
248 les relate to their conformation; the recent advent of single-molecule break-junction techniques prov
249                                 Prior to the advent of single-molecule fluorescence spectroscopy, man
250                                          The advent of small molecule-based targeted therapy has impr
251                                   The recent advent of smaller handheld microscopes is enabling acqui
252                                          The advent of social media and microblogging platforms has r
253  in the USA from 1988 to 1996 (preceding the advent of social media) using the time-space Scan statis
254                                     With the advent of social media, the impressions people make on o
255                                          The advent of soft lithography allowed for an unprecedented
256                                          The advent of species-diagnostic molecular tools in the 1990
257                                          The advent of stem cell-derived retinal organoids has brough
258                                   The recent advent of subcutaneous implantable cardioverter defibril
259                                          The advent of such technologies has rapidly accelerated the
260                                          The advent of super-resolution imaging (SRI) has created a n
261                                     Only the advent of super-resolution optical fluorescence microsco
262                                     With the advent of supramolecular chemistry and later nanotechnol
263                                          The advent of sustainable design or green building strategie
264                              Conversely, the advent of targeted therapies in the clinic has led to a
265 overall survival in white patients since the advent of targeted therapy, survival for African America
266  disease has been precluded until the recent advent of Tau tracer-based neuroimaging.
267                                          The advent of tau-targeted positron emission tomography trac
268                                   The recent advent of technologies enabling cell-type-specific recor
269                                     With the advent of technologies to obtain the complete sequence o
270                                     With the advent of technologies, cells can also be directly spott
271 h a significant drop that coincided with the advent of the 13-valent vaccine (PCV-13) in 2010.
272 om the Department's inception in 1919 to the advent of the Centennial Celebration of the Johns Hopkin
273                                     With the advent of the digital economy, increasing globalization
274                                          The advent of the first metal based therapeutic agent, cispl
275                                          The advent of the genomic era has necessitated the developme
276 isadvantages of the mercury catalyst and the advent of the gold catalysts for this important reaction
277                                 Prior to the advent of the Haber-Bosch process (the industrial fixati
278                                     With the advent of the Internet, drug discovery has become more d
279                                     With the advent of the new IFN-free regimens, highly effective an
280                                     With the advent of the omics era and accelerated development of t
281 A SCIENTIFIC COMMENTARY ON THIS ARTICLE: The advent of the positron emission tomography tracer (18)F-
282                                     With the advent of the Pottery Neolithic, genetic variation withi
283 ogical and computational advances harken the advent of their principal role in discovery.
284 thylation and potentially contributes to the advent of therapeutic agents for human diseases associat
285  correction has regained attention since the advent of time-of-flight PET/MR imaging.
286  for lasers since the 1960s, long before the advent of today's organic electronic devices.
287                                    Since the advent of transcatheter aortic valve replacement, the mu
288  systematic echocardiographic follow-up, the advent of transcatheter heart valve (THV) technologies c
289                                     With the advent of transcranial Doppler, measurement of cerebral
290                                          The advent of transition-metal catalysed strategies for form
291                                 The exciting advent of tuneable quantum cascade lasers allows for the
292                                          The advent of two-photon microscopy now reveals unprecedente
293                      In particular, with the advent of ultra-stable MOF materials, in conjunction wit
294                                          The advent of unbiased high-throughput sequencing and bioinf
295  shift in the late 1970s coincident with the advent of US national fisheries management policy, as we
296                                     With the advent of van der Waals heterostructures, new methods ha
297 o is consistent with the hypotheses that the advent of VT-AANAT contributed to the evolution of the p
298                                          The advent of whole exome/genome sequencing and the technolo
299                                     With the advent of whole genome sequencing we are in the midst of
300                                          The advent of X-ray free electron lasers (XFELs) is opening

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