ライフサイエンスコーパス: adventitial

1 reas of patchy or diffuse intimal, medial or adventitial abnormalities with thickening/accumulation o

2 at aortas, and this is markedly increased in adventitial and endothelial cells in Ang II-induced hype

3 r of diseases of the cardiopulmonary system, adventitial and interstitial fibroblasts are subjected t

4 numbers of inflammatory cells, and extensive adventitial and intimal neovascularity.

5 87b can contribute to cell death and loss of adventitial and medial integrity during hypertension-ind

6 al coronary arteries and in nonproliferating adventitial and neointimal cells 14 days after angioplas

7 ings and localized inflammatory cells to the adventitial and periadventitial domains of injured vesse

8 nding into periaortic vascular channels, and adventitial and periaortic inflammatory infiltrates were

9 a and media, less attention has been paid to adventitial and perivascular responses and their potenti

10 The active CMV infections involved adventitial and, less frequently, intimal cells.

11 Our findings indicate that adventitial angiogenesis stimulates intimal thickening b

12 Adventitial application of the O2--generating system xan

13 s included the measurement of neointimal and adventitial area and thickness.

14 - 0.03 mm; p < 0.001) and a 23% reduction in adventitial area normalized to vessel size (0.43 +/- 0.0

15 0 Gy, 0.00+/-0.01 mm(2); P<0.05) and larger adventitial areas (20 Gy, 2.25+/-0.75 mm(2); 30 Gy, 2.38

16 The change in diameter af adventitial arteriolar (14.5 to 42.0 microm initial diam

17 Tracheal adventitial arterioles (12.0 to 47.0 micro m initial dia

18 Tracheal adventitial arterioles (13.0 to 41.0 microns initial dia

19 r space can enter the artery either from the adventitial aspect or from the lumen after absorption by

20 s of medial disruption, predominantly on the adventitial aspect.

21 e progenitor cells provides new insight into adventitial biology and its participation in atheroscler

22 taining showed that Thy-1 was upregulated in adventitial blood vessels after balloon injury to the ca

23 es were drawn at the lumen-intimal and media-adventitial borders.

24 whether antagonism of PDGF signaling alters adventitial cell migration after balloon injury in rat c

25 d in a selective expansion of the outermost, adventitial cell population in the great vessels.

26 crest results in expansion restricted to an adventitial cell population of the developing great vess

27 Opn was also detected in this adventitial cell population, but in addition was express

28 We have previously shown that adventitial cell proliferation increases significantly 4

29 of alpha-smooth muscle actin observed in the adventitial cells after arterial injury may constrict th

30 in-Cre transgene targets perivascular cells (adventitial cells and pericyte-like cells) in WAT, and N

31 es, including both neuronal and non-neuronal adventitial cells and smooth muscle.

32 e the characteristics of coronary medial and adventitial cells and to compare the responses of corona

33 ponse to vascular stress or injury, resident adventitial cells are often the first to be activated an

34 hat reduced PD-L1 expression in VZV-infected adventitial cells contribute to persistent vascular infl

35 eported that only occasional fibroblasts and adventitial cells derived from c-kit positive progenitor

36 ce analyses to test whether VZV infection of adventitial cells downregulates PD-L1 showed decreased P

37 combinant gene expression to endothelial and adventitial cells in Ad.CMVeNOS veins; only endogenous n

38 ecent findings suggesting the involvement of adventitial cells in coronary repair have raised questio

39 n situ hybridization showed that peri-aortic adventitial cells in high fat-fed mice express Msx2.

40 O-1 is expressed in medial smooth muscle and adventitial cells in normotensive rat aortas, and this i

41 ents were designed to study the migration of adventitial cells in response to mechanical injury of th

42 evious studies suggest that the migration of adventitial cells into the neointima after balloon angio

43 n the lung, in myocytes in the heart, and in adventitial cells lining the arteries including the aort

44 d on day 14 suggested that the proliferating adventitial cells may migrate into the neointima.

45 kedly reduced in the stroma of heart valves, adventitial cells of the aortic root, perivascular and i

46 mRNA also was detected in adipocytes and in adventitial cells of vessels.

47 zation of the vascular wall by proliferative adventitial cells that contribute to the repair.

48 To examine the contribution of adventitial cells to the development of neointima, proli

49 All adventitial cells were negative for these proteins.

50 Adventitial cells were stained in situ with PKH26, a flu

51 l, localized to subpopulations of medial and adventitial cells, and the expression of leptin by arter

52 medial cells and growth factor production by adventitial cells, both of which resulted in maladaptive

53 served that large numbers of fibroblasts and adventitial cells, some smooth muscle and endothelial ce

54 rther define the changes in the phenotype of adventitial cells, the expression of three cytoskeletal

55 and bromodeoxyuridine labeling to activated adventitial cells, which translocated to neointima.

56 ut on extensive damage, they are replaced by adventitial cells.

57 restricted to subpopulations of intimal and adventitial cells.

58 n of smooth muscle alpha-actin expression in adventitial cells.

59 oronary arteries, respectively), and various adventitial cells.

60 strated rFGF2-SAP binding to medial SMCs and adventitial cells.

61 and neointima, but not within endothelial or adventitial cells.

62 Adventitial changes in porcine coronary arteries subject

63 These intimomedial interface and adventitial changes may play a role in the natural histo

64 elastic lamina (IEL) rupture, and medial and adventitial changes, including inflammation, fibrosis, a

65 Almost all adventitial ChAT-I bundles and thin fibers, and VIP-I me

66 response 3 days after injury over the entire adventitial circumference.

67 actor-beta1 (TGF-beta1)-related increases in adventitial collagen and reductions in medial elastin, w

68 distribution, however the fiber families of adventitial collagen are obscured by their waviness at n

69 Adventitial collagen content at the site of injury was i

70 normally but neointimal lesion formation and adventitial collagen deposition in response to carotid a

71 ributes to favorable arterial remodeling and adventitial collagen deposition via a mechanism that is

72 Adventitial collagen deposition was apparent after 28 da

73 angiotensin II infusion caused marked aortic adventitial collagen deposition, as quantified by Masson

74 The adventitial collagen exists as large wavy bundles of fib

75 This is accompanied by increased adventitial collagen, which may act as an external "scaf

76 s of interstitial (matrix) and perivascular (adventitial) collagen were analyzed with polarization mi

77 significantly greater when detected from the adventitial compared with the intimal aspect of the arte

78 es only expressed LacZ positive cells in the adventitial compartment; however, after injury in LacZ a

79 t, only diffuse fibrin was identified in the adventitial compartments of arteries from PAI-1(-/-) mic

80 al reference and stented segment luminal and adventitial contours were imported and reconstructed.

81 Adventitial DCN is reduced in abdominal aortic aneurysm

82 Activation of adventitial DCs initiates and maintains T cell responses

83 umatica (PMR), a subclinical variant of GCA, adventitial DCs were mature and produced the chemokines

84 Test the effects of adventitial delivery of Multistem in the peri-infarct pe

85 ne kinase-MB or troponin associated with the adventitial delivery of MultiStem.

86 livery of MultiStem with a first-in-coronary adventitial delivery system to determine the effects of

87 This was particularly true for adventitial delivery.

88 otid artery intima-media thickness and inter-adventitial diameter were measured by ultrasonography an

89 ventitia, along with macrophage recruitment, adventitial expansion, and development of thoracic and s

90 fic for eNOS documented both endothelial and adventitial expression in Ad.CMVeNOS arteries, whereas v

91 l consequences of activating this pathway on adventitial fibroblast (AF) migration in vitro.

92 The locations of MARs in aortic adventitial fibroblast (AoAF) cells were very stable (r

93 r ATP would modulate/mediate hypoxia-induced adventitial fibroblast growth.

94 rectly attenuates integrin-beta(3)-dependent adventitial fibroblast migration after inhibition of OPN

95 tibody (F11) pretreatment markedly inhibited adventitial fibroblast migration directed by exogenous O

96 observations provide direct demonstration of adventitial fibroblast migration into neointima of arter

97 s modulation by estrogen, and its effects on adventitial fibroblast migration.

98 rthermore, immunodepletion of p67(phox) from adventitial fibroblast particulates resulted in the loss

99 The emergence of a distinct adventitial fibroblast population with an epigenetically

100 Losartan reduced Ang II-induced VSMC and adventitial fibroblast proliferation but had no effect o

101 ively, our data demonstrate that ATP-induced adventitial fibroblast proliferation requires activation

102 cell types (ie, endothelial, smooth muscle, adventitial fibroblast) undergo site- and time-dependent

103 re, using a technique to isolate and culture adventitial fibroblasts (AdvFBs) and vasa vasorum endoth

104 wth of medial smooth muscle cells (SMCs) and adventitial fibroblasts (AFBs) that we have shown expres

105 (VZV)-infected primary human brain vascular adventitial fibroblasts (BRAFs), levels of beta interfer

106 mpared to mock-infected human brain vascular adventitial fibroblasts (HBVAFs), perineural cells (HPNC

107 1 induced upregulation of collagen in aortic adventitial fibroblasts and enhanced the expression of c

108 ncreased extracellular ATP concentrations in adventitial fibroblasts and in lung microvascular endoth

109 Thus NAD(P)H oxidases in adventitial fibroblasts and macrophages appear to modula

110 ling in PH, and uncover a cross-talk between adventitial fibroblasts and macrophages in which paracri

111 re the NADH/NAD(+) ratio in bovine and human adventitial fibroblasts and mouse lung tissues.

112 histochemical staining showed marker eGFP in adventitial fibroblasts and some macrophages, indicating

113 -generating activity was localized to aortic adventitial fibroblasts and was enhanced by the potent v

114 Activated adventitial fibroblasts are endowed with synthetic capab

115 ndothelial and smooth muscle cells, vascular adventitial fibroblasts contain a substantial NAD(P)H ox

116 Migration of adventitial fibroblasts contributes to vascular remodeli

117 in response to stimulation, whereas coronary adventitial fibroblasts demonstrated several characteris

118 ne fibroblasts) approaches, we observed that adventitial fibroblasts derived from hypertensive pulmon

119 increase in p21 expression that occurred in adventitial fibroblasts during the cell cycle.

120 We found that adventitial fibroblasts from calves with severe hypoxia-

121 Pulmonary adventitial fibroblasts from chronically hypoxic hyperte

122 rative, apoptosis-resistant, proinflammatory adventitial fibroblasts from human and bovine hypertensi

123 These findings support the involvement of adventitial fibroblasts in coronary repair and remodelin

124 ion in injured arteries as well as that from adventitial fibroblasts in vitro.

125 ting stimulus for subsets of bovine neonatal adventitial fibroblasts largely through Galpha(i/o)-medi

126 ation in both aortic smooth muscle cells and adventitial fibroblasts may contribute to development of

127 er balloon injury of the rat carotid artery, adventitial fibroblasts migrate in a luminal direction a

128 shown to act as a proliferative stimulus for adventitial fibroblasts of the pulmonary artery.

129 In vitro, coculture of monocytes and aortic adventitial fibroblasts produced MCP-1- and IL-6-enriche

130 injury triggers differentiation of activated adventitial fibroblasts to myofibroblasts, which may con

131 GF attenuates remodeling and contribution of adventitial fibroblasts to neointima formation after bal

132 This study demonstrates translocation of adventitial fibroblasts to neointima, their phenotypic m

133 ession of factor(s) controlling migration of adventitial fibroblasts via an ER-dependent mechanism.

134 IRS1 expression in adventitial fibroblasts was predominantly nuclear and nu

135 Primary cultures of VSMCs and adventitial fibroblasts were derived from female Sprague

136 of vascular smooth muscle cells (VSMCs) and adventitial fibroblasts were derived from female Sprague

137 Pulmonary adventitial fibroblasts were isolated from calves and hu

138 Primate aortic smooth muscle cells and adventitial fibroblasts were seeded into collagen I gels

139 Primary syngeneic adventitial fibroblasts were stably transduced with retr

140 Indeed, inhibition of miR-487b protected adventitial fibroblasts, and also medial smooth muscle c

141 rix deposition, an increase in the number of adventitial fibroblasts, and intimal thickening.

142 cells, pulmonary artery smooth muscle cell, adventitial fibroblasts, and pulmonary and systemic infl

143 lymphoid tissue and, when bound to pulmonary adventitial fibroblasts, change their phenotype to one t

144 In primary rat and human arterial adventitial fibroblasts, inhibition of miR-487b leads to

145 In cultured adventitial fibroblasts, TGF-beta1 induced increases in

146 lar inflammation is perpetuated by activated adventitial fibroblasts, which, through sustained produc

147 re required for ATP-induced proliferation of adventitial fibroblasts.

148 of soluble factor(s) directing migration of adventitial fibroblasts.

149 ism whereby estrogen attenuates migration of adventitial fibroblasts.

150 ess includes the activation and migration of adventitial fibroblasts.

151 uscle cells (VSMCs), inflammatory cells, and adventitial fibroblasts.

152 at recombinant eNOS protein was expressed in adventitial fibroblasts.

153 ress markers of smooth muscle precursors and adventitial fibrocytes, respectively, by E13.5.

154 ive remodeling, which coincided with reduced adventitial fibrosis and collagen deposition.

155 TGF-beta isoforms as major factors mediating adventitial fibrosis and negative remodeling after vascu

156 able effect on late remodeling by preventing adventitial fibrosis at the injury site.

157 medial smooth muscle cell degeneration, and adventitial fibrosis.

158 intimal hyperplasia, medial hypertrophy, and adventitial fibrosis.

159 Adventitial gene transfer may serve as a tool to study v

160 Genetic fate tracing indicates that adventitial Gli1(+) MSC-like cells migrate into the medi

161 O2- derived from adventitial gp91(phox)-based NAD(P)H oxidase contributes

162 ocked by KMD3213 (alpha1A-AR antagonist) and adventitial growth by AH11110A (alpha1B-AR antagonist),

163 positive in several biopsy specimens within adventitial histiocytes-macrophages, but these results d

164 matic quantification of intimal, medial, and adventitial histopathological features in 598 human aort

165 The adventitial homing of TGFbeta1+ CD68+ cells places them

166 duced proteoglycan deposition, and inhibited adventitial hypertrophy.

167 ch on the formation and structural nature of adventitial immune aggregates, potential mechanisms of c

168 three patterns: adventitial nodules, diffuse adventitial infiltrates, and neointimal infiltrates.

169 Medial and adventitial inflammation (P=0.01), medial fibrosis (P=0.

170 s characteristic of GCA, and 16 (36%) showed adventitial inflammation adjacent to viral antigen; no i

171 by increased oxidative stress, a promoter of adventitial inflammation and vasa vasorum neovasculariza

172 creased incidence of IEL rupture, medial and adventitial inflammation, medial fibrosis, and medial at

173 ntimal hemorrhage, and increased intimal and adventitial inflammation.

174 cterized by a strikingly increased number of adventitial inflammatory cells, highly proliferative, an

175 Histology demonstrated a marked adventitial inflammatory response in all allografts, wit

176 er intraluminal gene delivery or after intra-adventitial injection in carotid arteries of atheroscler

177 Our hypothesis was that adventitial injection of rapamycin nanoparticles would b

178 re randomized to the double-injury model and adventitial injection of saline (n=2) or 500 mug of nano

179 An intraluminal microinfusion catheter for adventitial injection represents an alternative to stent

180 Yorkshire pigs (20-25 kg; n=7) through intra-adventitial injections of collagenase (5 mL, 0.35 mg/mL)

181 mooth muscle cells (VSMCs) and in associated adventitial/interstitial fibroblasts of intramyocardial

182 centric layers of muscle cells and the outer adventitial layer are assembled and patterned around end

183 n demonstrated active invasion of the aortic adventitial layer by P. gingivalis.

184 with vessel walls stripped of the intimal or adventitial layer identified dendritic cells at the medi

185 hog (Shh) signaling domain restricted to the adventitial layer of artery wall that supports resident

186 IFN-gamma+ T cells aggregated in the adventitial layer of the inflamed artery where they were

187 ta and 37 in allograft) were analyzed in the adventitial layer with a total number of 8568 vectors pr

188 At 3 days, they were mainly present in the adventitial layer, decreasing at 7 days, with no fluores

189 The hypercellularity of the adventitial layer, proliferation of fibroblasts, and mod

190 but also induces profound remodelling of the adventitial layer.

191 Macrophages were present primarily in the adventitial layer; B lymphocytes were notably absent.

192 mphocyte (P<0.0179) invasion into medial and adventitial layers and inhibited associated depletion of

193 its mesenchymal cells to form the medial and adventitial layers of arterioles and venules during the

194 Observed reductions in early adventitial leukocyte infiltration and late medial cell

195 There were significantly fewer adventitial leukocytes at 3 days, P<0.001, but no differ

196 Beneath these lesions, adventitial leukocytes organize in clusters that resembl

197 e dose heterogeneity at both the intimal and adventitial levels.

198 Phenotypic transformation of intimal and adventitial lymphatics in atherosclerosis: a regulatory

199 Despite increased VEGF-C, we found that adventitial lymphatics regress during the course of form

200 ed VEGF-C in the atherosclerotic aortas, how adventitial lymphatics regress.

201 hts to previously unknown dynamic changes of adventitial lymphatics.

202 w of the contributions of the adventitia and adventitial lymphocytes to the development of atheroscle

203 d moderate to severe intimal, medial, and/or adventitial lymphocytic infiltration with intimal expans

204 d chemokine production, as well as transient adventitial macrophage accumulation and activation.

205 ry and characterization of resident vascular adventitial macrophage progenitor cells provides new ins

206 ansfer studies revealed that Sca-1(+)CD45(+) adventitial macrophage progenitor cells were not repleni

207 Rather adventitial macrophage progenitor cells were upregulated

208 Human adventitial macrophages displaying a CD14(+)/CD16(+) res

209 l hyperplasia with increased infiltration of adventitial macrophages expressing MCP-1.

210 In contrast to aortic adventitial macrophages, CD11c(+)MHC II(hi) DCs were poo

211 e CD45 isoform is more prevalent in resident adventitial macrophages.

212 migration and recruitment of mural cells and adventitial macrophages.

213 nd III collagen were largely found in either adventitial/medial or transmural locations.

214 Type VI collagen was adventitial or adventitial/medial.

215 Tofacitinib disrupted adventitial microvascular angiogenesis, reduced outgrowt

216 utral beta-galactosidase and, in contrast to adventitial microvessel endothelium, exhibited weak stai

217 endothelial cells) in large-vessel lumen and adventitial microvessel lumen of arteriopathic vessels.

218 Transduction of adventitial microvessels was enhanced by balloon injury

219 s Wnt2, Wnt5a, and Sca1 expression in aortic adventitial myofibroblast cultures.

220 metalloproteinase (MMP) activation in aortic adventitial myofibroblasts (AMFs) and A7r5 vascular smoo

221 We hypothesize that adventitial myofibroblasts are actively involved in the

222 These data suggest that adventitial myofibroblasts contribute to the process of

223 Aortic adventitial myofibroblasts from SM22-Cre;Msx1(fl/fl);Msx

224 Despite the prominent role that adventitial myofibroblasts seem to have in the postangio

225 We have previously shown that adventitial myofibroblasts synthesize growth factors tha

226 ng demonstrated that TnC expression began in adventitial myofibroblasts three days after injury.

227 Other vascular cells, including adventitial myofibroblasts, calcifying vascular cells, s

228 e in the recruitment and/or proliferation of adventitial myofibroblasts, possibly through the release

229 regions of Msx2 immunoreactivity in adjacent adventitial myofibroblasts, suggesting a potential parac

230 process is associated with the formation of adventitial myofibroblasts, which resemble medial smooth

231 pression early after vascular injury was the adventitial myofibroblasts.

232 Tenascin-C expression begins with adventitial myofibroblasts.

233 tion in alkaline phosphatase (TNAP)-positive adventitial myofibroblasts.

234 Adventitial nab-rapamycin injection was safe and signifi

235 tulated that the interaction between NO. and adventitial NAD(P)H oxidase-derived O2- contributes to i

236 Adventitial neovascularization occurs after balloon inju

237 This study suggests that adventitial neovascularization of vasa vasorum occurs in

238 y histological and biochemical alteration in adventitial nerves and correlated with improved hemodyna

239 mmunohistochemistry to endothelial cells and adventitial nerves of blood vessels.

240 16) and were distributed in three patterns: adventitial nodules, diffuse adventitial infiltrates, an

241 In middle cerebral arteries, all adventitial NOS-I bundles and fine fibers were coinciden

242 m gp91(phox-/-) mice, which lack significant adventitial O2-, exhibited greater EDR and were not affe

243 Adventitial oligoclonal resident B cells of atherosclero

244 Type VI collagen was adventitial or adventitial/medial.

245 racic aorta, which were oriented so that the adventitial or luminal surface could be preferentially e

246 The interaction between medial and adventitial pathology and the intimal atherosclerotic pr

247 st in part, by limiting leukocyte entry from adventitial/periadventitial tissues into injured vessels

248 Transplantation of adventitial pericytes (APCs) improves recovery from tiss

249 onocytes/macrophages in the pulmonary artery adventitial/perivascular areas of animals and humans wit

250 smural panarteritis and TLR5 ligands promote adventitial perivasculitis.

251 In the rat carotid injury model, local adventitial polymer-based delivery of radiolabeled linea

252 We identified a vascular adventitial population containing macrophage progenitor

253 Adventitial progenitors express the stem cell markers, S

254 findings implicate Gli1(+) cells as critical adventitial progenitors in vascular remodeling after acu

255 with a reduction in neointima formation and adventitial reaction after balloon injury.

256 microscopic evidence of a pronounced chronic adventitial reaction, with perivascular infiltration pro

257 or gadolinium chloride, prevented pulmonary adventitial remodeling (ie, production of collagen, fibr

258 facilitates migration of these cells during adventitial remodeling.

259 ury resulted in fibroblast proliferation and adventitial remodeling.

260 pand in number and are major contributors to adventitial remodeling.

261 ents, indicating an inhibitory effect on the adventitial response to injury.

262 Significant adventitial responses were associated with increased neo

263 xpress the stem cell markers, Sca1 and CD34 (adventitial sca1-positive progenitor cells [AdvSca1]), h

264 More recently, pars plana vitrectomy with adventitial sheathotomy has also been shown to be of ben

265 )) and patched-2 (Ptc2(lacZ)) reporter mice, adventitial Shh signaling activity was first detected at

266 Endogenous O2- was increased by treating the adventitial side of the aortas with Ang II (10 pmol/L),

267 In vivo, local application of VEGF to the adventitial side of the decellularized vessel increased

268 Arterial radiation resulted in a decrease in adventitial size, which was maximal for high-activity (3

269 s likely causes the transition of medial and adventitial smooth muscle cells (SMC) into classic myofi

270 Further study into the regulation of this adventitial source of O2- is important in elucidating th

271 EDR impairment was reversed by adventitial suffusion of superoxide dismutase (SOD) of a

272 This study suggests that adventitial superoxide anion can play a role in the path

273 adrenaline (NA) overflow at the blood vessel adventitial surface and vasoconstriction evoked by elect

274 eparin uniformly and at a steady rate to the adventitial surface of balloon-injured rat carotid arter

275 lded VSMC ( > 90%) while digestions from the adventitial surface yielded type 2 cells ( > 90%).

276 Adventitial TGF-beta1-related oxidative stress may play

277 Irradiated vessels demonstrated more adventitial thickening and fibrosis.

278 sis were associated with a significant focal adventitial thickening at 3, 7, 14, and 28 days after in

279 [FGF-R1DN]), respectively, signaling reduced adventitial thickening induced by VEGF and PR39 to the l

280 s initiated, although medial hypertrophy and adventitial thickening still developed.

281 ally by pulmonary artery medial hypertrophy, adventitial thickening, and neointimal proliferation.

282 ypes (intimal thickening, media hypertrophy, adventitial thickening, plexiform lesions, vascular prun

283 iance, decreased ankle-brachial indexes, and adventitial thickening.

284 h higher intimal thickness but not medial or adventitial thickness as measured by histology.

285 intimal area, maximal intimal thickness, and adventitial thickness were significantly reduced in both

286 in the number of macrophages present in the adventitial tissue underlying lesions.

287 nounced dilation and more modestly remodeled adventitial tissue.

288 Whether vector delivery was intraluminal or adventitial, transduction was observed in the adventitia

289 ipidemic ApoE(-/-) and LDL-R(-/-) mice, with adventitial transfer experiments demonstrating their dur

290 Adventitial transgene expression was demonstrated 24 h l

291 Adventitial transplantation of MSCs decreases Mcp-1 gene

292 IP NCs arose directly from adventitial vasa vasorum and were anatomically and quant

293 In balloon-injured coronary arteries, adventitial vasa vasorum density was increased (3.16+/-0

294 CE immunoreactivity was found in luminal and adventitial vasa vasorum endothelium.

295 rPAI-1(23) causes regression or collapse of adventitial vasa vasorum in hypercholesterolemic mice by

296 cellular and molecular mechanisms regulating adventitial vasa vasorum neovascularization, which occur

297 to examine the quantitative response of the adventitial vasa vasorum to balloon-induced coronary inj

298 of diffusion from the artery lumen and outer adventitial vasa vasorum, deposit proatherogenic plasma

299 of the atherosclerotic plaque and associated adventitial vasa vasorum.

300 Interestingly, adventitial vascularity significantly increased, suggest